Increased SIAH expression predicts ductal carcinoma in situ (DCIS) progression to invasive carcinoma

Breast Cancer Research and Treatment

Volumn 129, Issue 3, 2011, Pages 717-724

  Behling, Kathryn C ^a   Tang, Amy ^b   Freydin, Boris ^a   Chervoneva, Inna ^a   Kadakia, Sameep ^a   Schwartz, Gordon F ^a   Rui, Hallgeir ^a   Witkiewicz, Agnieszka K ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b MAYO CLINIC CANCER CENTER   (United States)

Author keywords

DCIS; Ductal carcinoma in situ; SIAH

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; PROTEIN SIAH; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER MORPHOLOGY; CANCER RECURRENCE; CELL NUCLEUS; COMEDO; CONTROLLED STUDY; DISEASE ACTIVITY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRADUCTAL CARCINOMA; INVASIVE CARCINOMA; MAJOR CLINICAL STUDY; MASTECTOMY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; TUMOR NECROSIS;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; DISEASE PROGRESSION; FEMALE; HUMANS; MASTECTOMY; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NUCLEAR PROTEINS; PREDICTIVE VALUE OF TESTS; REFERENCE VALUES; ROC CURVE; UBIQUITIN-PROTEIN LIGASES;

EID: 80052598428     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-1254-8     Document Type: Article

References (22)

1. A Jemal R Siegel E Ward Y Hao J Xu MJ Thun 2009 Cancer statistics, 2009 CA Cancer J Clin 59 4 225 249 19474385 10.3322/caac.20006
2. BA Virnig TM Tuttle T Shamliya RL Kane 2010 Ductal carcinoma in situ of the breast: a systematic review of incidence, treatment, and outcomes J Natl Cancer Inst 102 170 178 20071685 10.1093/jnci/djp482
3. GH Sakorafas DR Farley G Peros 2008 Recent advances and current controversies in the management of DCIS of the breast Cancer Treat Rev 34 6 483 497 18490111 10.1016/j.ctrv.2008.03.001 1:CAS:528:DC%2BD1cXhtV2is7%2FM
4. M Valenzuela TB Julian 2007 Ductal carcinoma in situ: biology, diagnosis, and new therapies Clin Breast Cancer 7 676 681 17919347 10.3816/CBC.2007.n.026 1:CAS:528:DC%2BD2sXhtVOrsbbO (Pubitemid 47344729)
5. ME Sanders PA Schuyler WD Dupont DL Page 2005 The natural history of low-grade ductal carcinoma in situ of the breast in women treated by biopsy only revealed over 30 years of long-term follow-up Cancer 103 12 2481 2484 15884091 10.1002/cncr.21069 (Pubitemid 40800525)
6. RW Carthew GM Rubin 1990 Seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye Cell 63 561 577 2146028 10.1016/0092-8674(90)90452-K 1:CAS:528:DyaK3MXit1ansbg%3D (Pubitemid 20374101)
7. AH Tang TP Neufeld E Kwan GM Rubin 1997 PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism Cell 90 459 467 9267026 10.1016/S0092-8674(00)80506-1 1:CAS:528:DyaK2sXlsVKrs7w%3D (Pubitemid 27347236)
8. CM House A Möller DD Bowtell 2009 Siah proteins: novel drug targets in the Ras and hypoxia pathways Cancer Res 69 23 8835 8838 19920190 10.1158/0008-5472.CAN-09-1676 1:CAS:528:DC%2BD1MXhsV2itLrI
9. RL Schmidt CH Park AU Ahmed JH Gundelach NR Reed S Cheng BE Knudsen AH Tang 2007 Inhibition of RAS-mediated transformation and tumorigenesis by targeting the downstream E3 ubiquitin ligase seven in absentia homologue Cancer Res 67 24 11798 11810 18089810 10.1158/0008-5472.CAN-06-4471 1:CAS:528:DC%2BD2sXhsVCjs7jI
10. AU Ahmed RL Schmidt CH Park NR Reed SE Hesse CF Thomas JR Molina C Deschamps P Yang MC Aubry AH Tang 2008 Effect of disrupting seven-in-absentia homolog 2 function on lung cancer cell growth J Natl Cancer Inst 100 22 1606 1629 19001609 10.1093/jnci/djn365 1:CAS:528:DC%2BD1cXhsVWmsbjJ
11. D Palmieri D Fitzgerald SM Shreeve E Hua JL Bronder RJ Weil S Davis AM Stark MJ Merino R Kurek HM Mehdom G Davis SM Steinberg PS Meltzer K Aldape PS Steeq 2009 Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis Mol Cancer Res 7 9 1438 1445 19723875 10.1158/1541-7786.MCR-09-0234 1:CAS:528:DC%2BD1MXhtFCjtbrE
12. MS Roh SH Hong JS Jeong HC Kwon MC Kim SH Cho JH Yoon TH Hwang 2004 Gene expression profiling of breast cancers with emphasis of beta-catenin regulation J Korean Med Sci 19 2 275 282 15082903 10.3346/jkms.2004.19.2.275 1:CAS:528:DC%2BD2cXksVSkt78%3D (Pubitemid 38591804)
13. LM McShane DG Altman W Sauerbrei SE Taube M Gion GM Clark 2005 Reporting recommendations for tumor marker prognostic studies J Clin Oncol 23 36 9067 9072 16172462 10.1200/JCO.2004.01.0454
14. LC Collins N Achacoso L Nekhlyudov SW Fletcher R Haque CP Quesenberry Jr B Puligandla NS Alshak LC Goldstein AM Gown SJ Schnitt LA Habel 2009 Relationship between clinical and pathologic features of ductal carcinoma in situ and patient age: an analysis of 657 patients Am J Surg Pathol 33 12 1802 1808 19950406 10.1097/PAS.0b013e3181b7cb7a
15. NA Rodrigues D Dillon D Carter N Parisot BG Haffty 2003 Differences in the pathologic and molecular features of intraductal breast carcinoma between younger and older women Cancer 97 6 1393 1403 12627502 10.1002/cncr.11204 (Pubitemid 36297768)
16. DB Cornfield JP Palazzo GF Schwartz SA Goonewardene AJ Kovatich I Chervoneva T Hyslop R Schwarting 2004 The prognostic significance of multiple morphologic features and biologic markers in ductal carcinoma in situ of the breast: a study of a large cohort of patients treated with surgery alone Cancer 100 11 2317 2327 15160334 10.1002/cncr.20260 (Pubitemid 38657878)
17. Hosmer DW, Lemeshow S (2000) Applied logistic regression, 2nd edn. Wiley, New York, pp 346-347
18. PN Peduzzi J Concato E Kemper TR Holford A Feinstein 1996 A simulation study of the number of events per variable in logistic regression analysis J Clin Epidemiol 99 1373 1379 10.1016/S0895-4356(96)00236-3 (Pubitemid 27028925)
19. VL Tsikitis MA Chung 2006 Biology of ductal carcinoma in situ classification based on biologic potential Am J Clin Oncol 29 3 305 310 16755185 10.1097/01.coc.0000198740.33617.2f (Pubitemid 44270940)
20. L Ding CG Kleer 2006 Enhancer of Zeste 2 as a marker of preneoplastic progression in the breast Cancer Res 66 19 9352 9355 17018586 10.1158/0008-5472.CAN-06-2384 1:CAS:528:DC%2BD28XhtVamsr3F (Pubitemid 44623628)
21. L Ding C Erdmann AM Chinnaiyan SD Merajver CG Kleer 2006 Identification of EZH2 as a molecular marker for a precancerous state in morphologically normal breast tissues Cancer Res 66 8 4095 4099 16618729 10.1158/0008-5472.CAN-05-4300 1:CAS:528:DC%2BD28XjsFSltrs%3D
22. DT Chen A Nasir A Culhane C Venkataramu W Fulp R Rubio T Wang D Agrawal SM McCarthy M Gruidl G Bloom T Anderson J White J Quackenbush T Yeatman 2010 Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue Breast Cancer Res Treat 119 2 335 346 19266279 10.1007/s10549-009-0344-y