A facile synthesis and biological activity of novel tetrahydrobenzo[4′,5′]thieno[3′,2′:5,6]pyrido[4, 3-d]pyrimidin-4(3H)-ones

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 23, 2009, Pages 6713-6716

  Ren, Qingyun ^a   Liang, Yong Ju ^b   He, Hongwu ^a   Fu, Liwu ^b   Gu, Yucheng ^a,c  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

Author keywords

Antifungal activity; Antitumor activity; Aza Wittig reaction; Pyrido 4,3 d pyrimidin 4(3H) one; Synthesis

Indexed keywords

ANTIFUNGAL AGENT; MULTIDRUG RESISTANCE PROTEIN 1; PYRIMIDINE DERIVATIVE; TETRAHYDROBENZO[40,50]THIENO[30,20:5,6]PYRIDO[4,3 D]PYRIMIDIN 4(3H)ONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; BIOASSAY; BOTRYTIS CINEREA; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG INHIBITION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; PROTEIN EXPRESSION;

ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; BOTRYTIS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; KB CELLS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PYRIMIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

BOTRYOTINIA FUCKELIANA;

EID: 72149105345     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.09.117     Document Type: Article

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