Dual and triple therapy to prevent mother-to-child transmission of HIV in a resource-limited setting - lessons from a South African programme

South African Medical Journal

Volumn 101, Issue 9, 2011, Pages 651-654

  Geddes, Rosemary ^a   Giddy, Janet ^b   Butler, Lisa M ^c   van Wyk, Erika ^b   Crankshaw, Tamaryn ^b   Esterhuizen, Tonya M ^d   Knight, Stephen ^a  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b MCCORD HOSPITAL   (South Africa)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

DIDANOSINE; EFAVIRENZ PLUS LAMIVUDINE PLUS ZIDOVUDINE; LAMIVUDINE PLUS NEVIRAPINE PLUS STAVUDINE; LAMIVUDINE PLUS ZIDOVUDINE; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; NEVIRAPINE; ZIDOVUDINE;

ARTICLE; CONTROLLED STUDY; DRUG DOSE REGIMEN; FEMALE; FOLLOW UP; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV TEST; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION PREVENTION; INTRAUTERINE INFECTION; MAJOR CLINICAL STUDY; NEWBORN; NEWBORN CARE; PREGNANCY OUTCOME; PREGNANT WOMAN; PRENATAL CARE; SINGLE DRUG DOSE; SOUTH AFRICA; TREATMENT OUTCOME; VERTICAL TRANSMISSION;

ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CHILD; DRUG THERAPY, COMBINATION; FEMALE; HIV INFECTIONS; HUMANS; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; SOUTH AFRICA;

EID: 80052576364     PISSN: 02569574     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. UNAIDS. Report on the Global AIDS Epidemic, 2010. Geneva: UNAIDS, 2010.
2. Working Group on MTCT of HIV. Rates of mother-to-child transmissionof HIV-1 in Africa, America and Europe: results of 13 perinatal studies. J Acquir Immune Defic Syndr Hum Retrovirol 1995;8:506-510.
3. Department of Health. National HIV and Syphilis Antenatal Sero-prevalence Survey South Africa 2009. Pretoria: National Department of Health, 2010.
4. Bradshaw D, Chopra M, Kerber K, et al. Every death counts: use of mortality audit data for decision making to save the lives of mothers, babies, and children in South Africa. Lancet 2008;371:1294-304.
5. Bradshaw D, Bourne D, Nannan N. What are the Leading Causes of Death among South African Children? Cape Town: Medical Research Council of South Africa, 2003.
6. UNICEF. Monitoring Progress on the Implementation of Programs to Prevent Mother to Child Transmission of HIV. PMTCT Reportcard, 2005. New York: UNICEF, 2005.
7. WHO/UNAIDS/UNICEF. Towards Universal Access: Scaling Up Priority HIV/AIDS Interventions in the Health Sector. Progress Report, 2007. Geneva: WHO, 2007.
8. Jourdain G, Ngo-Giang-Huong N, Le Coeur S, et al. Intrapartum exposure to nevirapine and subsequent maternal responses to nevirapine-based antiretroviral therapy. N Engl J Med 2004;351(3):229-240.
9. Lockman S, Shapiro RL, Smeaton LM, et al. Response to antiretroviral therapy after a single, peripartum dose of nevirapine. N Engl J Med 2007;356(2):135-147.
10. Geddes R, Knight S, Reid S, Giddy J, Esterhuizen T, Roberts C. Prevention of mother-to-child transmission of HIV programme: low vertical transmission in KwaZulu-Natal, South Africa. S Afr Med J 2008;98(6):458-462.
11. Branson BM, Handsfield HH, Lampe MA, et al. Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR Recomm Rep 2006;55(RR-14):1-17.
12. World Health Organization. Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants. Geneva: WHO, 2004.
13. Rollins N, Mzolo S, Little K, Horwood C, Newell ML. Surveillance of mother-to-child transmission prevention programmes at immunization clinics: the case for universal screening. AIDS 2007;21(10):1341-1347.
14. Stinson K, Boulle A, Coetzee D, Abrams EJ, Myer L. Initiation of highly active antiretroviral therapy among pregnant women in Cape Town, South Africa. Trop Med Int Health 2010;15(7):825-32.
15. Nassali M, Nakanjako D, Kyabayinze D, Beyeza J, Okoth A, Mutyaba T. Access to HIV/AIDS care for mothers and children in sub-Saharan Africa: adherence to the postnatal PMTCT program. AIDS Care 2009;21(9):1124-1131.
16. South African National AIDS Council. HIV & AIDS and STI National Strategic Plan 2007-2011. Pretoria: Department of Health, 2007.
17. Coetzee D, Hilderbrand K, Boulle A, et al. Effectiveness of the first district-wide programme for the prevention of mother-to-child transmission of HIV in South Africa. Bull World Health Organ 2005;83(7):489-494.
18. Draper B, Abdullah F. A review of the mother-to-child prevention of transmission programme of the Western Cape provincial government, 2003-2004. S Afr Med J 2008;98(6):431-434.