Prohibitin is overexpressed in Huh-7-HCV and Huh-7.5-HCV cells harboring in vitro transcribed full-length hepatitis C virus RNA

Virology Journal

Volumn 8, Issue , 2011, Pages

  Dang, Shuang Suo ^a   Sun, Ming Zhu ^a   Yang, E ^a   Xun, Meng ^a   Ma, Li ^b   Jia, Zhan Sheng ^b   Wang, Wen Jun ^a   Jia, Xiao Li ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

HCVcc; mRNA level; prohibitin; protein level

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROHIBITIN; MESSENGER RNA; REPRESSOR PROTEIN; VIRUS RNA;

ARTICLE; CONTROLLED STUDY; DNA TRANSCRIPTION; HEPATITIS C VIRUS; HEPATOMA CELL; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; WESTERN BLOTTING; BIOSYNTHESIS; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HEPATITIS C; HOST PATHOGEN INTERACTION; METABOLISM; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; TUMOR CELL CULTURE; VIROLOGY; VIRUS REPLICATION;

HEPATITIS C VIRUS;

BLOTTING, WESTERN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION; HEPACIVIRUS; HEPATITIS C; HOST-PATHOGEN INTERACTIONS; HUMANS; PLASMIDS; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; RNA, MESSENGER; RNA, VIRAL; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION; VIRUS REPLICATION;

EID: 80052569750     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-8-424     Document Type: Article

References (23)

1. Characterization of thiobarbituric acid derivatives as inhibitors of hepatitis C virus NS5B polymerase. Lee JH, Lee S, Park MY, Myung H, Virol J 2011 14 8 18
2. Advances in nucleoside monophoaphate prodrugs as anti-HCV agents. Bobeck DR, Schinazi RF, Coats SJ, Antivir Ther 2010 15 7 935 50 10.3851/IMP1667 21041908
3. In-vitro antiviral activity of Solanum nigrum against Hepatitis C Virus. Javed T, Ashfaq UA, Riaz S, Rehman S, Riazuddin S, Virol J 2011 19 8 26
4. Hepatitis C virus infection: a "liasion a trois" amongst the virus, the host, and chronic low-level inflammation for human survival. Bamaba V, J Hepatol 2010 53 4 752 61 10.1016/j.jhep.2010.06.003 20673595
5. Development of novel therapies for hepatitis C. Lemon SM, Mckeating JA, Pietschmann T, Frick DN, Glenn JS, Tellinghuisen TL, Symons J, Furman PA, Antiviral Res 2010 86 1 79 92 10.1016/j.antiviral.2010.02.003 20417376
6. Pegylated interferons for the treatment of chronic hepatitis C: pharmacological and clinical differences between peginterferon-alpha-2a and peginterferon-alpha-2b. Foster GR, Drugs 2010 70 2 147 65 10.2165/11531990- 000000000-00000 20108989
7. Prohibitin deficiency blocks proliferation and induces apoptosis in human hepatoma cells: Molecular mechanisms and functional implications. Sanchez-Quiles V, Santamaria E, Segura V, Sesma L, Prieto J, Corrales FJ, Proteomics 2010 10 8 1609 20 10.1002/pmic.200900757 20186755
8. Prohibitin is a novel target gene of vitamin D involved in its antiproliferative action in breast cancer cells. Peng X, Mthta R, Wang S, Chellappan S, Mthta RG, Cancer Res 2006 66 14 7361 9 10.1158/0008-5472.CAN-06- 1004 16849588 (Pubitemid 44197720)
9. Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication. Rizwani W, Alexandrow M, Chellappan S, Cell Cycle 2009 8 1621 1629 10.4161/cc.8.10.8578 19377303
10. Prohibitin expression is increased in phorbol ester-treated chronic leukemic B-lymphocytes. Woodlock TJ, Bethlendy G, Segel GB, Blood Cells Mol Dis 2001 27 27 34 10.1006/bcmd.2000.0348 11162143 (Pubitemid 32299751)
11. Differential immunization identifies PHB1/PHB2 as blood-borne tumor antigens. Mengwasser J, Piau A, Schlag P, Sleeman JP, Oncogene 2004 23 7430 7435 10.1038/sj.onc.1207987 15286703 (Pubitemid 39382145)
12. The significance of prohibitin and c-Met/hepatocye growth factor receptor in the progression of cervical adenocarcinoma. Tsai HW, Chow NH, Lin CP, Chan SH, Chou CY, Ho CL, Hum Pathol 2006 37 198 204 10.1016/j.humpath.2005.10.012 16426920 (Pubitemid 43099840)
13. Prohibitin: a potential biomarker for tissue-based detection of gastric cancer. Kang X, Zhang L, Sun J, Ni Z, Ma Y, Chen X, Sheng X, Chen T, J Gastroenterol 2008 43 618 625 10.1007/s00535-008-2208-3 18709484
14. Analysis of the expression protein profiles of lung squamous carcinoma cell using shot-gun proteomics strategy. Nan Y, Yang S, Tian Y, Zhang W, Zhou B, Bu L, Huo S, Med Oncol 2009 26 215 221 10.1007/s12032-008-9109-4 18988000
15. Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein. Tsutsumi T, Matsuda M, Aizaki H, Moriya K, Hepatology 2009 50 2 378 86 10.1002/hep.22998 19591124
16. The human prohibitin gene located on chromosome 17q21 is mutated in sporadic breaset cancer. Sato T, Saito H, Swensen J, Olifant A, Wood C, Danner D, Sakamoto T, Takita K, Kasumi F, Miki Y, Cancer Res 1992 52 1643 1646 1540973
17. The prohibitins: emerging roles in diverse functions. Mishra S, Murphy LC, Murphy LJ, J Cell Mol Med 2006 10 353 363 10.1111/j.1582-4934.2006.tb00404.x 16796804 (Pubitemid 44870184)
18. Prohibitin facilitates cellular senescence by recruiting specific corepressors to inhibit E2F target genes. Rastogi S, Joshi B, Dasgupta P, Morris M, Wright K, Chellappan S, Mol Cell Biol 2006 26 4161 4171 10.1128/MCB.02142-05 16705168 (Pubitemid 43788018)
19. Prohibitin induces the transcriptional activity of p53 and is exported from the nucleus upon apoptotic signaling. Fusaro G, Dasgupta P, Rastogi S, Joshi B, Chellappan S, J Biol Chem 2003 278 47853 47861 10.1074/jbc.M305171200 14500729 (Pubitemid 37523233)
20. A putative coiled-coil domain of prohibitin is sufficient to repress E2F1-mediated transcription and induce apoptosis. Joshi B, Ko D, Ordonez-Ercan D, Chellappan SP, Biochem Biophys Res Commun 2003 312 459 466 10.1016/j.bbrc.2003.10.148 14637159 (Pubitemid 37445194)
21. The 3' untranslated region of prohibitin and cellular immortalization. Jupe ER, Liu XT, Kiehlbauch JL, McClung JK, Dell'Orco RT, Exp Cell Res 1996 224 128 135 10.1006/excr.1996.0120 8612677
22. Androgens target prohibitn to regulate proliferation of prostate cancer cells. Gamble SC, Odontiadis M, Waxm an J, Oncogene 2004 23 2996 3004 10.1038/sj.onc.1207444 14968116 (Pubitemid 38648190)
23. Two-dimensional electrophoresis map of the human hepatocellular carcinoma cell line, HCC-M, and identification of the separated proteins by mass spectrometry. Seow TK, Ong SE, Liang RC, Ren EC, Chan L, Ou K, Chung MC, Electrophoresis 2000 21 1787 1813 10.1002/(SICI)1522-2683(20000501)21:9<1787: :AID-ELPS1787>3.0.CO;2-A 10870966 (Pubitemid 30394872)