Inhibition of subcutaneous growth of ehrlich ascites carcinoma (EAC) tumor by post-immunization with EAC-cell gangliosides and its anti-idiotype antibody in relation to tumor angiogenesis, apoptosis, cell cycle and infiltration of CD4+, CD8+ lymphocytes, NK cells, suppressor cells and APC-cells in tumor

Indian Journal of Experimental Biology

Volumn 49, Issue 8, 2011, Pages 574-584

  Mondal, Bipasha ^a   Saha, Sandip ^a  

^a CHITTARANJAN NATIONAL CANCER INSTITUTE   (India)

Author keywords

Angiogenesis; Anti idiotype; Apoptosis; Gangliosides; Tumor

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; CANCER VACCINE; GANGLIOSIDE;

ANIMAL; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CYCLE; DRUG EFFECT; EHRLICH ASCITES TUMOR; FEMALE; IMMUNOLOGY; IMMUNOTHERAPY; METHODOLOGY; MOUSE; NATURAL KILLER CELL; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; RAT; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIGEN-PRESENTING CELLS; APOPTOSIS; CANCER VACCINES; CARCINOMA, EHRLICH TUMOR; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL CYCLE; CELL LINE, TUMOR; FEMALE; GANGLIOSIDES; IMMUNOTHERAPY; KILLER CELLS, NATURAL; MICE; NEOVASCULARIZATION, PATHOLOGIC; RATS; RATS, SPRAGUE-DAWLEY;

MUS;

EID: 80052569542     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Yamamoto S, Yamamoto T, Saxton RE, Hoon DSB & Irie RF, Anti-idiotype monoclonal antibody carrying the internal image of ganglioside GM3, J. Natl. Cancer Inst, 82 (1990) 1757.
2. McCaffery M, Yao T J, Williams L, Livingston P. O., Houghton A. N. & Chapman P.B., Immunization of melanoma patients with BEC2 anti-idiotypic monoclonal antibody that mimics GD3 ganglioside: enhanced immunogenicity when combined with adjuvant, Clin Cancer Res, 2 (1996) 679.
3. Foon KA, Sen G, Hutchins L, Kashala O, Baral R, Banerjee M, Chakraborty M, Garrison J, Reisfeld R & Bhattacharya- Chatterjee M, Antibody responses in melanoma patients immunized with an anti-idiotype antibody mimicking disialoganglioside GD2, Clin Cancer Res, 4 (1998) 1117.
4. Jinnohara T, Tsujisaka M, Sasaki K, Hinoda Y, Taniguchi M & Imai K, Anti-tumor effect of internal image bearing antiidiotypic monoclonal antibody in relation to GM3 ganglioside, Int J Cancer, 76 (1998)343.
5. Saha S, Mondal S, Suppression of Ehrlich ascites tumor growth by immunization with ganglioside GT1b of its origin, its IgM antibody or anti-idiotype of the anti-GT1b IgM, Indian J Exp Biol, 38 (2000) 1207.
6. Saha S & Mondal S, Suppression of Ehrlich subcutaneous solid tumor growth by immunization with ganglioside GT1b of its origin, its IgM antibody or anti-idiotype antibody, J Exp Clin Cancer Res, 20 (1) (2001) 75.
7. Saha S & Mohanty KC, Secretion of metastasis related gangliosides by mouse B16-melanoma in circulation in vivo and in culture media, Indian J Expt Biol, 42 (2004) 976.
8. Sen G, Chakraborty M, Foon KA, Reisfeld RA & Bhattacharya-chatterjee M, Pre-clinical evaluationin nonhuman primate of murine monoclonal anti-idiotype antibody that mimics the disiao ganglioside GD2, Clinical Cancer Res, 3 (1997) 196
9. Díaz A, Alfonso M, Alonso R, Saurez G, Troche M, Catalá M & María R, Immune response in breast cancer patients immunized with an anti-idiortype antibody mimicking NeuGc containing gangliosides, Biotecnologia Aplicada, 19 (3) (2002) 119.
10. Cheung NKV, Guo HF, Heller G & Cheung IY, Induction of AB3 and AB3/antibody was associated with long term survival after anti-GD2 antibody therapy of stage 4 neuroblastoma 1, Clin Cancer Res, 6 (2000) 2653.
11. Field SK & Morrison DC, An anti-idiotype antibody which mimics the inner-core region of lipopolysaccharide protects mice against a lethal challenge with endotoxin, Infect Immun, 1994 (1994) 3994.
12. Chakrabarti D & Ghosh SK, Induction of syngeneic cytotoxic T lymphocytes against a B cell tumor. III. MHC class I-restricted CTL recognizes the processed form(s) of idiotype, Cell Immunol, 144 (1992) 455.
13. Robbins RA, Denton GWL, Hardcastle JD, Austin EB, Baldwin RW & Durrant L, Antitumor immune response and interleukin 2 production produced in colorectal cancer patients by immunization with human monoclonal antiidiotypic antibody, Cancer Res, 51 (1991) 5425.
14. Chakraborty M, Mukerjee S, Foon KA, Kohler H, Ceriani R L & Bhattachary-Chatterjee M, Induction of human breast cancer-specific antibody responses in cynomolgus monkeys by a murine monoclonal anti-idiotype antibody, Cancer Res, 55 (1995) 1525.
15. Samonigg H, Wilders-Truschnig M, Loibner H, Plot R, Rot A, Kuss I, Werner G, Stoger H, Wrann M, Herlyn D & Koprowski H, Immune response to tumor antigens in a patient with colorectal cancer after immunization with anti-idiotype antibody, Clin Immunol Immunopathol, 65 (1992) 271.
16. Mittelman A, Chen ZJ, Yang H, Wong GY & Ferrone S, Human high molecular weight melanoma-associated antigen (HMW-MAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma, Proc Natl Acad Sci USA, 89 (1992) 466.
17. Lehmann HP, Zwicky C, Waibel R & Stahel RA, Tumor-antigen-specific humoral immune response of animals to anti-idiotypic antibodies and comparative serological analysis of patients with small-cell lung carcinoma, Int J Cancer, 50 (1992) 86.
18. Fagerberg J, Frodin J E, Wigzell H & Mellstedt H, Induction of an immune network cascade in cancer patients treated with monoclonal antibodies (ab1). I. May induction of ab1- reactive T cells and anti-anti-idiotypic antibodies (ab1) lead to tumor regression after mAb therapy?, Cancer Immunol Immunother, 37 (1993) 264.
19. Foon KA, Oseroff AR, Vaickus L, Greenberg SJ, Russell D, Bernstein Z, Pincus S, Kohler H, Seon B, Tahaoglu E, Beers T, Chakraborty M & Bhatacharya- Chatterjee M, Immune responses in patients with T-cell lymphoma treated with an anti-idiotype antibody mimicking a highly restricted T-cell antigen, Clin Cancer Res, 1 (1995)1285.
20. Chetterjee S, Tripathi P, Chakraborty M, Yannelli J Wang H, Foon K, Maier C, Blalock J & Bhattacharya-Chatterjee M, Molecular mimicry of carcinoembryonic antigen by peptides derived from the structure of an anti-idiotype antibody, Cancer Res, 58 (1998) 1217.
21. Ragnhammar P, Fagerberg J, Frodin J-E, Wersall P, Hansson L-O & Mellstedt H, Granulocyte/macrophagecolony- stimulating factor augments the induction of antibodies, especially anti-idiotypic antibodies to therapeutic monoclonal antibodies, Cancer Immunol Immunother, 40 (1995) 367.
22. Fagerberg J, Ragnhammar P, Liljefors M, Hjelm AL, Mellstedt H & Frodin JE, Humoral anti-idiotypic and antiidiotypic immune response in cancer patients treated with monoclonal antibody 17-1A, Cancer Immunol Immunother, 42 (1996) 81.
23. Nepom GT, Nelson KA, Holbeck SL, Hellstrom I & Hellstrom KE, Induction of immunity to a human tumor marker by in vivo administration of anti-idiotypic antibodies in mice, Proc Natl Acad Sci USA, 81 (1984) 2864.
24. Fagerberg J, Frodin JE, Ragnhammar P, Steinitz M, Wigzell H & Mellstedt H, Induction of an immune network cascade in cancer patients treated with monoclonal antibodies (ab1). II. Is induction of anti-idiotype reactive T cells (T3) of importance for tumor response to mAb therapy? Cancer Immunol Immunother, 38 (1994) 149.
25. Foon KA, Chakraborty M, John WJ, Sherratt A, Kohler H & Bhattacharya-Chatterjee M, Immune response to the carcinoembryonic antigen in patients treated with an antiidiotype antibody vaccine, J Clin Investig, 96 (1995) 334.
26. Horiike S, Misawa S, Kaneko H, Sasai Y, Kobayashi M, Fujii H, Tanaka S, Yagita M, Abe T, Kashima K & Taniwaki M, Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of nos. 5 and/or 7 and its possible relationship to replication error phenotype, Leukemia(Baltimore), 13 (1999) 1235.
27. Fagerberg J, Hjelm AL, Ragnhammar P, Frodin J E, Wigzell H & Mellstedt H, Tumor regression in monoclonal antibody-treated patients correlates with the presence of antiidiotype- reactive T lymphocytes, Cancer Res, 55 (1995) 1824.
28. Herlyn D, Ross AH & Koprowski H, Anti-idiotypic antibodies bear the internal image of a human tumor antigen. Science, 232 (1986) 100.