Design, synthesis and anticancer activity of novel dihydrobenzofuro[4,5-b] [1,8]naphthyridin-6-one derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 19, 2011, Pages 5730-5734

  Kang, Jin Ah ^a   Yang, Zunhua ^a   Lee, Ji Yeon ^a   De, Umasankal ^a   Kim, Tae Hyung ^a   Park, Ji Young ^a   Lee, Hye Jin ^a   Park, Yun Jung ^a   Chun, Pusoon ^a   Kim, Hyung Sik ^a   Jeong, Lak Shin ^b   Moon, Hyung Ryong ^a  

^a Pusan National University   (South Korea)

^b Ewha Womans University   (South Korea)

Author keywords

Anticancer activity; Dihydrobenzofuro 4,5 b 1,8 naphthyridin 6 one; Epoxide; G2 M phase arrest

Indexed keywords

ACRIDONE DERIVATIVE; ACRONINE; DIHYDROBENZOFURAN DERIVATIVE; DIHYDROBENZOFURO[4,5 B][1,8]NAPHTHYRIDIN 6 ONE DERIVATIVE; DOXORUBICIN; NAPHTHYRIDINE DERIVATIVE; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG DESIGN; DRUG DISCOVERY; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; MALE; NAPHTHYRIDINES; STEREOISOMERISM; XANTHONES;

EID: 80052566082     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.08.016     Document Type: Article

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