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Volumn 17, Issue 6, 2011, Pages 477-486

Deep sequencing and predictive modeling as a concept for therapeutic decision-making in oncology;"Deep sequencing" und prädiktive Modellierung als Konzept therapeutischer Entscheidungsfindungen in der Onkologie

Author keywords

Omics analysis; Oncogenic pathway modeling; Personalized medicine; Targeted therapy; Tumor

Indexed keywords

ARTICLE; CANCER GENETICS; CANCER THERAPY; COMPUTER MODEL; HUMAN; MEDICAL DECISION MAKING; MOLECULAR INTERACTION; ONCOLOGY; PERSONALIZED MEDICINE; PREDICTION; SIGNAL TRANSDUCTION;

EID: 80052564937     PISSN: 09478965     EISSN: 14330415     Source Type: Journal    
DOI: 10.1007/s00761-011-2025-9     Document Type: Article
Times cited : (3)

References (19)
  • 1
    • 0037435030 scopus 로고    scopus 로고
    • Mass spectrometry-based proteomics
    • DOI 10.1038/nature01511
    • Aebersold R, Mann M (2003) Mass spectrometry-based proteomics. Nature 422:198-207. (Pubitemid 36362757)
    • (2003) Nature , vol.422 , Issue.6928 , pp. 198-207
    • Aebersold, R.1    Mann, M.2
  • 3
    • 0030882666 scopus 로고    scopus 로고
    • Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation
    • DOI 10.1074/jbc.272.39.24113
    • Finco TS, Westwick JK, Norris JL et al (1997) Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation. J Biol Chem 272:24113-24116. (Pubitemid 27418602)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.39 , pp. 24113-24116
    • Finco, T.S.1    Westwick, J.K.2    Norris, J.L.3    Beg, A.A.4    Der, C.J.5    Baldwin Jr., A.S.6
  • 4
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 5
    • 74849109743 scopus 로고    scopus 로고
    • Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF
    • Heidorn SJ, Milagre C, Whittaker S et al (2010) Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF. Cell 140:209-221.
    • (2010) Cell , vol.140 , pp. 209-221
    • Heidorn, S.J.1    Milagre, C.2    Whittaker, S.3
  • 6
    • 77951115122 scopus 로고    scopus 로고
    • International network of cancer genome projects
    • Hudson TJ, Anderson W, Artez A et al (2010) International network of cancer genome projects. Nature 464:993-998.
    • (2010) Nature , vol.464 , pp. 993-998
    • Hudson, T.J.1    Anderson, W.2    Artez, A.3
  • 7
    • 61449182121 scopus 로고    scopus 로고
    • Principles of cancer therapy: Oncogene and non-oncogene addiction
    • Luo J, Solimini NL, Elledge SJ (2009) Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 136:823-837.
    • (2009) Cell , vol.136 , pp. 823-837
    • Luo, J.1    Solimini, N.L.2    Elledge, S.J.3
  • 8
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • DOI 10.1038/nrc1097
    • Malumbres M, Barbacid M (2003) RAS oncogenes: the first 30 years. Nat Rev Cancer 3:459-465. (Pubitemid 37328850)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 10
    • 70450164376 scopus 로고    scopus 로고
    • Oncogenic RAS enables DNA damage- and p53-dependent differentiation of acute myeloid leuk-emia cells in response to chemotherapy
    • Meyer M, Rubsamen D, Slany R et al (2009) Oncogenic RAS enables DNA damage- and p53-dependent differentiation of acute myeloid leukemia cells in response to chemotherapy. PLoS One 4:e7768.
    • (2009) PLoS One , vol.4
    • Meyer, M.1    Rubsamen, D.2    Slany, R.3
  • 11
    • 53749099948 scopus 로고    scopus 로고
    • Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: A Cancer and Leukemia Group B study
    • Neubauer A, Maharry K, Mrozek K et al (2008) Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study. J Clin Oncol 26:4603-4609.
    • (2008) J Clin Oncol , vol.26
    • Neubauer, A.1    Maharry, K.2    Mrozek, K.3
  • 12
    • 15744372810 scopus 로고    scopus 로고
    • KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
    • Pao W, Wang TY, Riely GJ et al (2005) KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2:e17.
    • (2005) PLoS Med , vol.2
    • Pao, W.1    Wang, T.Y.2    Riely, G.J.3
  • 13
    • 68049102319 scopus 로고    scopus 로고
    • Inhibition of PI3 K and MEK: It is all about combinations and biomarkers
    • Rexer BN, Ghosh R, Arteaga CL (2009) Inhibition of PI3 K and MEK: it is all about combinations and biomarkers. Clin Cancer Res 15:4518-4520.
    • (2009) Clin Cancer Res , vol.15 , pp. 4518-4520
    • Rexer, B.N.1    Ghosh, R.2    Arteaga, C.L.3
  • 14
    • 78650373172 scopus 로고    scopus 로고
    • Drug discovery: How melanomas bypass new therapy
    • Solit D, Sawyers CL (2010) Drug discovery: How melanomas bypass new therapy. Nature 468:902- 903.
    • (2010) Nature , vol.468 , pp. 902-903
    • Solit, D.1    Sawyers, C.L.2
  • 15
    • 58149352266 scopus 로고    scopus 로고
    • MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis
    • Stein U, Walther W, Arlt F et al (2009) MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nat Med 15:59-67.
    • (2009) Nat Med , vol.15 , pp. 59-67
    • Stein, U.1    Walther, W.2    Arlt, F.3
  • 16
    • 47649124124 scopus 로고    scopus 로고
    • A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome
    • Sultan M, Schulz MH, Richard H et al (2008) A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. Science 321:956-960.
    • (2008) Science , vol.321 , pp. 956-960
    • Sultan, M.1    Schulz, M.H.2    Richard, H.3
  • 17
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • DOI 10.1038/nm1087
    • Vogelstein B, Kinzler KW (2004) Cancer genes and the pathways they control. Nat Med 10:789-799. (Pubitemid 39070849)
    • (2004) Nature Medicine , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 19
    • 80052566144 scopus 로고    scopus 로고
    • Prediction in the face of uncertainty: A Monte Carlo-based simulation strategy for systems biology of cancer treatment
    • Wierling C, Kühn A, Daskalaki A et al (2011) Prediction in the face of uncertainty: a Monte Carlo-based simulation strategy for systems biology of cancer treatment. Mutat Res under review.
    • (2011) Mutat Res under Review
    • Wierling, C.1    Kühn, A.2    Daskalaki, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.