Our experience of treatment of cribriform morular variant of papillary thyroid carcinoma; difference in clinicopathological features of FAP-associated and sporadic patients

Endocrine Journal

Volumn 58, Issue 8, 2011, Pages 685-689

  Ito, Yasuhiro ^a   Miyauchi, Akira ^a   Ishikawa, Hideki ^b   Hirokawa, Mitsuhiro ^a   Kudo, Takumi ^a   Tomoda, Chisato ^a   Miya, Akihiro ^a  

^a KUMA HOSPITAL   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Cribriform morular variant; FAP; Papillary thyroid carcinoma; Prognosis

Indexed keywords

ADENOMATOUS POLYP; ADOLESCENT; ADULT; AGE DISTRIBUTION; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CRIBRIFORM MORULAR VARIANT; DISEASE ASSOCIATION; FAMILIAL POLYPOSIS; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; RECURRENT CANCER; THYROID NODULE; THYROID PAPILLARY CARCINOMA; THYROIDECTOMY; TUMOR DIFFERENTIATION; TUMOR VOLUME;

ADENOCARCINOMA; ADENOMATOUS POLYPOSIS COLI; ADOLESCENT; ADULT; DIAGNOSIS, DIFFERENTIAL; FEMALE; GENES, APC; HUMANS; NEOPLASM METASTASIS; NEOPLASMS, MULTIPLE PRIMARY; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS; THYROID NEOPLASMS; TUMOR BURDEN; YOUNG ADULT;

EID: 80052564695     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ11-0022     Document Type: Article

References (18)

1. Crail HW (1949) Multiple primary malignancies arising in the rectum, brain, and the thyroid: report of a case. U S Nav Med Bull 49: 123-128.
2. Camiel MR, Mule JE, Alexander LL, Benninghoff DL (1968) Association of thyroid carcinoma with Gardner's syndrome in siblings. N Engl J Med 278: 1056-1058.
3. Plail RO, Bussey HJ, Glazer G, Thomspon JP (1987) Adenomatous polyposis: an association with carcinoma of the thyroid. Br J Surg 74: 377-380.
4. Harach HR, Williams GT, Williams ED (1994) Familial adenomatous polyposis associated thyroid carcinoma: a distinct type of follicular cell neoplasm. Histopathology 25: 549-561.
5. Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H, Joslyn G, Stevens J, Spiro L, Robertson M (1991) Identification and characterization of the familial adenomatous polyposis coli. Gene. Cell 66: 589-600.
6. Kinzler KW, Nibert MC, Su LK, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hedge P, McKechnie D (1991) Identification of FAP locus gene from chromosome 5q21. Science 253: 661-665.
7. Cetta F, Pelizzo MR, Caria MC, Barbarisi A (1999) Genetics and clinicopathological findings in thyroid carcinomas associated with familial adenomatous polyposis. Am J Pathol 155: 7-9.
8. Cameselle-Teijeiro J, Chan JK (1999) Cribriformmorular variant of papillary carcinoma: A distinctive variant representing the sporadic counterpart of familial adenomatous polyposis-associated thyroid carcinoma? Mod Pathol 12: 400-411.
9. Ng SB, Sittampalm K, Goh YH, Eu KW (2003) Cribriform-morular variant of papillary carcinoma: The sporadic counterpart of familial adenomatous polyposis- associated thyroid carcinoma. A case report with clinical and molecular genetic correlation. Pathology 35: 42-46.
10. Xu B, Yoshimoto K, Miyauchi A, Kuma S, Mizusawa N, Hirokawa M, Sano T (2003) Cribirform-morular variant of papillary thyroid carcinoma: A pathological and molecular genetic study with evidence of frequent somatic mutations in exon 3 of the beta-catenin gene. J Pathol 199: 58-67.
11. Tomoda C, Miyauchi A, Uruno T, Takamura Y, Ito Y, Kobayashi K, Matsuzuka F, Kuma S, Kuma K, Kakudo K (2004) Cribriform-morular variant of papillary thyroid carcinoma: clue to early detection of familial adenomatous polyposis-associated colon cancer. World J Surg 28: 886-889.
12. Hirokawa M, Maekawa M, Kuma S, Miyauchi A (2010) Cribriform-morular variant of papillary thyroid carcinoma- cytological and immunocytochemical findings of 18 cases. Diag Cytopathol 38: 890-896.
13. Kuma S, HIrokawa M, Xu B, Miyauchi A, Kakudo K, Sano T (2004) Cribriform-morular variant of papillary thyroid carcinoma. Report of a case showing morules with peculiar nuclear clearing. Acta Cytol 48: 431-436.
14. Kurihara K, Shimizu S, Chong J, Hishima T, Funata N, Kashiwagi H, Nagai H, Miyaki M, Fukayama M (2000) Nuclear localization of immunoreactive beta-catenin is specific to familial adenomatous polyposis in papillary thyroid carcinoma. Jpn J Cancer Res 91: 1100-1102.
15. th ed. New York: Wiley- Liss.
16. Perrier ND, van Heerden JA, Goellner JR, Williams ED, Gharib H, Marchesa P, Church JM, Fazio VW, Larson DR (1998) Thyroid cancer in patients with familial adenomatous polyposis. World J Surg 22: 738-742.
17. Cameselle-Teijeiro J, Menasce LP, Yap BK, Colaco RJ, Castro P, Celestino R, Ruiz-Ponte C, Soares P, Sobrinho-Simoes M (2009) Cribriform-morular variant of papillary thyroid carcinoma. Molecular characterization of a case with neuroendocrine differentiation and aggressive behavior. Am J Clin Pathol 131: 134-142.
18. Ito Y, Higashiyama T, Takamura Y, Miya A, Kobayashi K, Matsuzuka F, Kuma K, Miyauchi A (2007) Risk factors for recurrence to the lymph node in papillary thyroid carcinoma patients without preoperatively detectable lateral node metastasis: validity of prophylactic modified radical neck dissection. World J Surg 31: 2085-2091.