Cribriform-morular variant of papillary thyroid carcinoma - Cytological and immunocytochemical findings of 18 cases

Diagnostic Cytopathology

Volumn 38, Issue 12, 2010, Pages 890-896

  Hirokawa, Mitsuyoshi ^a   Maekawa, Miyoko ^a   Kuma, Seiji ^a   Miyauchi, Akira ^a  

^a KUMA HOSPITAL   (Japan)

Author keywords

cribriform morular variant; papillary carcinoma; peculiar nuclear clearing; polyposis coli; tall cell; thyroid

Indexed keywords

BETA CATENIN; BIOTIN;

ADOLESCENT; ADULT; ARTICLE; ASPIRATION BIOPSY; CLINICAL ARTICLE; CYTOPATHOLOGY; DIAGNOSTIC ACCURACY; EARLY DIAGNOSIS; ECHOGRAPHY; FEMALE; HISTIOCYTE; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; PRIORITY JOURNAL; SPINDLE CELL; THYROID PAPILLARY CARCINOMA;

ADENOCARCINOMA; ADOLESCENT; ADULT; CARCINOMA, PAPILLARY; CELL AGGREGATION; CELL NUCLEUS; CELL SHAPE; FEMALE; HUMANS; HYALIN; IMMUNOHISTOCHEMISTRY; THYROID NEOPLASMS; YOUNG ADULT;

EID: 78649668039     PISSN: 87551039     EISSN: 10970339     Source Type: Journal    
DOI: 10.1002/dc.21309     Document Type: Article

References (24)

1. Cetta F, Pelizzo MR, Curia MC, Barbarisi A,. Genetics and clinicopathological findings in thyroid carcinomas associated with familial adenomatous polyposis. Am J Pathol 1999; 155: 7-9.
2. Bell B, Mazzaferri EL,. Familial adenomatous polyposis (Gardner's syndrome) and thyroid carcinoma. A case report and review of the literature. Dig Dis Sci 1993; 38: 185-190.
3. Kelly MD, Hugh TB, Field AS, Fitzsimons R,. Carcinoma of the thyroid gland and Gardner's syndrome. Aust N Z J Surg 1993; 63: 505-509.
4. Cameselle-Teijeiro J, Chan JK,. Cribriform-morular variant of papillary carcinoma: A distinctive variant representing the sporadic counterpart of familial adenomatous polyposis-associated thyroid carcinoma? Mod Pathol 1999; 12: 400-411.
5. Harach HR, Williams GT, Williams ED,. Familial adenomatous polyposis associated thyroid carcinoma: A distinct type of follicular cell neoplasm. Histopathology 1994; 25: 549-561.
6. Tomoda C, Miyauchi A, Uruno T, et al. Cribriform-morular variant of papillary thyroid carcinoma: Clue to early detection of familial adenomatous polyposis-associated colon cancer. World J Surg 2004; 28: 886-889.
7. Ng SB, Sittampalam K, Goh YH, Eu KW,. Cribriform-morular variant of papillary carcinoma: The sporadic counterpart of familial adenomatous polyposis-associated thyroid carcinoma. A case report with clinical and molecular genetic correlation Pathology 2003; 35: 42-46.
8. Xu B, Yoshimoto K, Miyauchi A, Kuma S, Mizusawa N, Hirokawa M, Sano T,. Cribriform-morular variant of papillary thyroid carcinoma: A pathological and molecular genetic study with evidence of frequent somatic mutations in exon 3 of the beta-catenin gene. J Pathol 2003; 199: 58-67.
9. Plail RO, Bussey HJ, Glazer G, Thomson JP,. Adenomatous polyposis: An association with carcinoma of the thyroid. Br J Surg 1987; 74: 377-380.
10. Chong J, Koshiishi N, Kurihara K, Kubono S, Kawai T, Fukayama M,. Aspiration and imprint cytopathology of thyroid carcinoma associated with familial adenomatous polyposis. Diagn Cytopathol 2000; 23: 101-105.
11. Kameyama K, Takami H,. FAP associated thyroid carcinoma in mother and her daughter. Fam Cancer 2001; 1: 83-86.
12. Cameselle-Teijeiro J, Ruiz-Ponte C, Loidi L, Suarez-Penaranda J, Baltar J, Sobrinho-Simoes M,. Somatic but not germline mutation of the APC gene in a case of cribriform-morular variant of papillary thyroid carcinoma. Am J Clin Pathol 2001; 115: 486-493.
13. Kuma S, Hirokawa M, Xu B, Miyauchi A, Kukudo K, Sano T,. Cribriform-morular variant of papillary thyroid carcinoma. Report of a case showing morules with peculiar nuclear clearing. Acta Cytol 2004; 48: 431-436.
14. Chuah KL, Hwang JS, Ng SB, Tan PH, Poh WT, Au VS,. Cytologic features of cribriform-morular variant of papillary carcinoma of the thyroid: A case report. Acta Cytol 2005; 49: 75-80.
15. Hirokawa M, Kuma S, Miyauchi A, et al. Morules in cribriform-morular variant of papillary thyroid carcinoma: Immunohistochemical characteristics and distinction from squamous metaplasia. APMIS 2004; 112: 275-282.
16. Ylagan LR, Dehner LP, Huettner PC, Lu D,. Columnar cell variant of papillary thyroid carcinoma. Report of a case with cytologic findings. Acta Cytol 2004; 48: 73-77.
17. Jayaram G,. Cytology of columnar-cell variant of papillary thyroid carcinoma. Diagn Cytopathol 2000; 22: 227-229.
18. Solomon A, Gupta PK, LiVolsi VA, Baloch ZW,. Distinguishing tall cell variant of papillary thyroid carcinoma from usual variant of papillary thyroid carcinoma in cytologic specimens. Diagn Cytopathol 2002; 27: 143-148.
19. Cristallini EG, Bolis GB, Francucci M,. Diagnosis of thyroid metastasis of colonic adenocarcinoma by fine needle aspiration biopsy. Acta Cytol 1990; 34: 363-365.
20. Kuma S, Hirokawa M, Miyauchi A, Kakudo K, Katayama S,. Cytologic features of hyalinizing trabecular adenoma of the thyroid. Acta Cytol 2003; 47: 399-404.
21. Papi G, Corrado S, LiVolsi VA,. Primary spindle cell lesions of the thyroid gland: An overview. Am J Clin Pathol 2006; 125 (Suppl): S95-S123.
22. Gamachi A, Kashima K, Daa T, Nakatani Y, Tsujimoto M, Yokoyama S,. Aberrant intranuclear localization of biotin, biotin-binding enzymes, and beta-catenin in pregnancy-related endometrium and morule-associated neoplastic lesions. Mod Pathol 2003; 16: 1124-1131.
23. Das DK,. Intranuclear cytoplasmic inclusions in fine-needle aspiration smears of papillary thyroid carcinoma: A study of its morphological forms, association with nuclear grooves, and mode of formation. Diagn Cytopathol 2005; 32: 264-268.
24. Dalal KM, Moraitis D, Iwamoto C, Shaha AR, Patel SG, Ghossein RA,. Clinical curiosity: Cribriform-morular variant of papillary thyroid carcinoma. Head Neck 2006; 28: 471-476.