Localization of Melatonin receptor 1 in mouse retina and its role in the circadian regulation of the electroretinogram and dopamine levels

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Sengupta, Anamika ^a   Baba, Kenkichi ^a   Mazzoni, Francesca ^c   Pozdeyev, Nikita V ^b   Strettoi, Enrica ^c   Iuvone, P Michael ^b   Tosini, Gianluca ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; MELATONIN 1 RECEPTOR; 3,4 DIHYDROXYPHENYLACETIC ACID;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TYPE; CELLULAR DISTRIBUTION; CIRCADIAN RHYTHM; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; ELECTRORETINOGRAM; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PHOTOSENSITIVITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RETINA CONE; RETINA GANGLION CELL; RETINA ROD; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; ANIMAL; ELECTRORETINOGRAPHY; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; METABOLISM; PHYSIOLOGY; RETINA; WESTERN BLOTTING;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCADIAN RHYTHM; DOPAMINE; ELECTRORETINOGRAPHY; IMMUNOHISTOCHEMISTRY; MICE; RECEPTOR, MELATONIN, MT1; RETINA;

EID: 80052554358     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024483     Document Type: Article

References (25)

1. Wiechmann AF, Summers JA, (2008) Circadian rhythms in the eye: the physiological significance of melatonin receptors in ocular tissues. Prog Retin Eye Res 27: 137-160.
2. Jockers R, Maurice P, Boutin JA, Delagrange P, (2008) Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new? Br J Pharmacol 154: 1182-1195.
3. Meyer P, Pache M, Loeffler KU, Brydon L, Jockers R, et al. (2002) Melatonin MT-1-receptor immunoreactivity in the human eye. Br J Ophthalmol 86: 1053-1057.
4. Baba K, Pozdeyev NV, Mazzoni F, Contreras-Alcantara S, Liu C, et al. (2009) Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor. Proc Natl Acad Sci U S A 106: 15043-15048.
5. Goto M, Oshima I, Tomita T, Ebihara S, (1989) Melatonin content of the pineal gland in different mouse strains. J Pineal Res 7: 195-204.
6. Tosini G, Menaker M, (1998) The clock in the mouse retina: melatonin synthesis and photoreceptor degeneration. Brain Res 789: 221-228.
7. Contreras-Alcantara S, Baba K, Tosini G, (2011) Removal of Melatonin Receptor Type 1 Increases Intraocular Pressure and Retinal Ganglion Cells Death in the Mouse. Neurosci Lett 494: 61-64.
8. Storch KF, Paz C, Signorovitch J, Raviola E, Pawlyk B, et al. (2007) Intrinsic circadian clock of the mammalian retina: importance for retinal processing of visual information. Cell 130: 730-41.
9. Cameron MA, Barnard AR, Hut RA, Bonnefont X, van der Horst GT, et al. (2008) Electroretinography of wild-type and Cry mutant mice reveals circadian tuning of photopic and mesopic retinal responses. J Biol Rhythms 23: 489-501.
10. Dubocovich ML, (1983) Melatonin is a potent modulator of dopamine release in the retina. Nature 306: 782-786.
11. Nir I, Haque R, luvone PM, (2000) Diurnal metabolism of dopamine in the mouse retina. Brain Res 870: 118-125.
12. Doyle SE, Grace MS, McIvor W, Menaker M, (2002) Circadian rhythms of dopamine in mouse retina: the role of melatonin. Vis Neurosci 19: 593-601.
13. Pozdeyev NV, Tosini G, Ali F, Rozov S, Lee RH, et al. (2008) Dopamine modulates diurnal and circadian rhythms of protein phosphorylation in photoreceptor cells of mouse retina. Eur J Neurosci 27: 26691-26700.
14. Brydon L, Roka F, Petit L, de Coppet P, Tissot M, et al. (1999) Dual signaling of human Mel1a melatonin receptors via G(i2), G(i3), and G(q/11) proteins. Mol Endocrinol 13: 2025-2038.
15. Fujieda H, Hamadanizadeh SA, Wankiewicz E, Pang SF, Brown GM, (1999) Expression of mt1 melatonin receptor in rat retina: evidence for multiple cell targets for melatonin. Neuroscience 93: 793-799.
16. Rada JA, Wiechmann AF, (2006) Melatonin receptors in chick ocular tissues: implications for a role of melatonin in ocular growth regulation. Invest Ophthalmol Vis Sci 47: 25-33.
17. Liu C, Fukuhara C, Wessel JH, Iuvone PM, Tosini G, (2004) Localization of Aa-nat mRNA in the rat retina by fluorescence in situ hybridization and laser capture microdissection. Cell Tissue Res 315: 197-201.
18. Tosini G, Davidson AJ, Fukuhara C, Kasamatsu M, Castanon-Cervantes O, (2007) Localization of a circadian clock in mammalian photoreceptors. FASEB J 21: 3866-3871.
19. Chen W, Baler R, (2000) The rat arylalkylamine N-acetyltransferase E-box: differential use in a master vs. a slave oscillator. Brain Res Mol Brain Res 81: 43-50.
20. Sakamoto K, Liu C, Kasamatsu M, Pozdeyev NV, Iuvone PM, et al. (2005) Dopamine regulates melanopsin expression in intrinsically photosensitive retinal ganglion cells. Eur J Neuroscience 22: 3536-3544.
21. Tosini G, Pozdeyev NV, Sakamoto K, Iuvone PM, (2008) The Circadian Clock System in Mammalian Retina. BioEssays 30: 624-633.
22. Barnard AR, Hattar S, Hankins MW, Lucas RJ, (2006) Melanopsin regulates visual processing in the mouse retina. Curr Biol 16: 389-395.
23. Liu C, Weaver D, Jin X, Shearman L, Pieschl R, et al. (1997) Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron 19: 91-102.
24. Provencio I, Rollag MD, Castrucci AM, (2002) Photoreceptive net in the mammalian retina. This mesh of cells may explain how some blind mice can still tell day from night. Nature 415: 493.
25. Bradford MM, (1976) A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.