Use of the light-dark box to compare the anxiety-related behavior of virgin and postpartum female rats

Pharmacology Biochemistry and Behavior

Volumn 100, Issue 1, 2011, Pages 130-137

  Miller, Stephanie M ^a   Piasecki, Christopher C ^a   Lonstein, Joseph S ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Anxiety; Black white box; Fear; GABA; Lactation; Maternal behavior

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE; BICUCULLINE; N METHYL BETA CARBOLINE 3 CARBOXAMIDE; PENTETRAZOLE; PICROTOXIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BEHAVIOR; BINDING SITE; COMPARATIVE STUDY; CONTROLLED STUDY; EXPERIMENTAL TEST; FEMALE; GABAERGIC TRANSMISSION; LIGHT DARK BOX TEST; LIGHT DARK CYCLE; MAZE TEST; NONHUMAN; POSTPARTUM HEMORRHAGE; PRIORITY JOURNAL; RAT;

ANIMALS; ANXIETY; DARKNESS; FEMALE; LIGHT; MALE; MOTOR ACTIVITY; POSTPARTUM PERIOD; PREGNANCY; RATS; RATS, LONG-EVANS; SEXUAL BEHAVIOR, ANIMAL;

RATTUS; RODENTIA;

EID: 80052530634     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2011.08.002     Document Type: Article

References (75)

1. D. Agrati, M.J. Zuluaga, A. Fernández-Guasti, A. Meikle, and A. Ferreira Maternal condition reduces fear behaviors but not the endocrine response to an emotional threat in virgin female rats Horm Behav 53 2008 232 240 (Pubitemid 350309382)
2. A receptors Br J Pharmacol 144 2005 357 366 (Pubitemid 40313682)
3. A receptor channel J Gen Physiol 129 2007 145 159 (Pubitemid 46184872)
4. L.J. Bertoglio, and A.P. Carobrez Previous maze experience required to increase open arms avoidance in rats submitted to the elevated plus-maze model of anxiety Behav Brain Res 108 2000 197 203 (Pubitemid 30084836)
5. G. Biala, and M. Kruk Amphetamine-induced anxiety-related behavior in animal models Pharmacol Rep 59 2007 636 644 (Pubitemid 351586554)
6. M.L. Boccia, and C.A. Pedersen Brief vs. long maternal separations in infancy: contrasting relationships with adult maternal behavior and lactation levels of aggression and anxiety Psychoneuroendocrinology 26 2001 657 672 (Pubitemid 32743176)
7. M. Bourin, and M. Hascöet The mouse light/dark box test Eur J Pharmacol 463 2003 55 65 (Pubitemid 36205072)
8. F. Chaouloff, M. Durand, and P. Mormede Anxiety- and activity-related effects of diazepam and chlordiazepoxide in the rat light/dark and dark/light tests Behav Brain Res 85 1997 27 35 (Pubitemid 27116147)
9. B.J. Cole, M. Hillmann, D. Seidelmann, M. Klewer, and G.H. Jones Effects of benzodiazepine receptor partial inverse agonists in the elevated plus maze test of anxiety in the rat Psychopharmacology 121 1995 118 126
10. R.L. Commissaris, J.S. Verbanac, V.L. Markovska, H.J. Altman, and T.J. Hill Anxiety-like and depression-like behavior in Maudsley reactive (MR) and non-reactive (NMRA) rats Prog Neuropsychopharmacol Biol Psychiatry 20 1996 491 501 (Pubitemid 26168826)
11. M.N. Cook, R.W. Williams, and L. Flaherty Anxiety-related behaviors in the elevated zero-maze are affected by genetic factors and retinal degeneration Behav Neurosci 115 2001 468 476 (Pubitemid 32378175)
12. B. Costall, B.J. Jones, M.E. Kelly, R.J. Naylor, and D.M. Tomkins Exploration of mice in a black and white test box: validation as a model of anxiety Pharmacol Biochem Behav 32 1989 777 785 (Pubitemid 19162403)
13. J.N. Crawley Neuropharmacologic specificity of a simple animal model for the behavioral actions of benzodiazepines Pharmacol Biochem Behav 15 1981 695 699 (Pubitemid 12195249)
14. J.N. Crawley, P. Skolnick, and S.M. Paul Absence of intrinsic antagonist actions of benzodiazepine antagonists on an exploratory model of anxiety in the mouse Neuropharmacology 23 1984 531 537 (Pubitemid 14134633)
15. A. Dalvi, and R.J. Rodgers GABAergic influences on plus-maze behaviour in mice Psychopharmacology 128 1996 380 397 (Pubitemid 26417680)
16. L. De Angelis The anxiogenic-like effects of pentylenetetrazole in mice treated chronically with carbamazepine or valproate Meth Find Exp Clinl Pharmacol 14 1992 767 771 (Pubitemid 23076463)
17. A receptor: neurochemical, neurophysiological, and behavioral effects CNS Drug Rev 13 2007 475 501 (Pubitemid 350233472)
18. C. Fernandes, M.I. González, C.A. Wilson, and S.E. File Factor analysis shows that female rat behaviour is characterized primarily by activity, male rats are driven by sex and anxiety Pharmacol Biochem Behav 64 1999 731 738
19. A. Fernandez-Guasti, and O. Picazo Changes in burying behavior during the estrous cycle: effect of estrogen and progesterone Psychoneuroendocrinology 17 1992 681 689 (Pubitemid 23043131)
20. A. Fernández-Guasti, O. Picazo, and A. Ferreira Blockade of the anxiolytic action of 8-OH-DPAT in lactating rats Pharmacol Biochem Behav 59 1998 45 50 (Pubitemid 28053678)
21. A. Fernández-Guasti, A. Ferreira, and O. Picazo Diazepam, but not buspirone, induces similar anxiolytic-like actions in lactating and ovariectomized Wistar rats Pharmacol Biochem Behav 70 2001 85 93 (Pubitemid 32786970)
22. A. Ferreira, O. Picazo, N. Uriarte, M. Pereira, and A. Fernández-Guasti Inhibitory effect of buspirone and diazepam, but not of 8-OH-DPAT, on maternal behavior and aggression Pharmacol Biochem Behav 66 2000 389 396 (Pubitemid 30394628)
23. A. Ferreira, M. Pereira, D. Agrati, N. Uriarte, and A. Fernández-Guasti Role of maternal behavior on aggression, fear and anxiety Physiol Behav 77 2002 197 204 (Pubitemid 35373875)
24. R.J. Figueira, M.F. Peabody, and J.S. Lonstein Oxytocin receptor activity in the ventrocaudal periaqueductal gray modulates anxiety-related behavior in postpartum rats Behav Neurosci 122 2008 618 628 (Pubitemid 351787840)
25. S.E. File Behavioural effects of pentylenetetrazole reversed by chlordiazepoxide and enhanced by RO 15-1788 Naunyn Schmiedebergs Arch Pharmacol 326 1984 129 131 (Pubitemid 14091351)
26. S.E. File, and R.G. Lister Do the reductions in social interaction produced by picrotoxin and pentylenetetrazole indicate anxiogenic actions? Neuropharmacology 23 1984 793 796 (Pubitemid 14089162)
27. A.S. Fleming, and C. Luebke Timidity prevents the virgin female rat from being a good mother: emotionality differences between nulliparous and parturient females Physiol Behav 27 1981 863 868 (Pubitemid 12181180)
28. C.A. Frye, S.M. Petralia, and M.E. Rhodes Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3alpha,5alpha-THP Pharmacol Biochem Behav 67 2000 587 596 (Pubitemid 32103570)
29. S.C. Gammie, A.F. Seasholtz, and S.A. Stevenson Deletion of corticotropin-releasing factor binding protein selectively impairs maternal, but not intermale aggression Neuroscience 157 2008 502 512
30. S. Hansen Mechanisms involved in the control of punished responding in mother rats Horm Behav 24 1990 186 197 (Pubitemid 20184132)
31. S. Hansen, A. Ferreira, and M.E. Selart Behavioural similarities between mother rats and benzodiazepine treated non maternal animals Psychopharmacology 86 1985 344 347 (Pubitemid 15064963)
32. E. Hard, and S. Hansen Reduced fearfulness in the lactating rat Physiol Behav 35 1985 641 643 (Pubitemid 16237722)
33. M. Hascöet, and M. Bourin A new approach to the light/dark test procedure in mice Pharmacol Biochem Behav 60 1998 645 653 (Pubitemid 28341925)
34. N.D. Henderson, M.G. Turri, J.C. DeFries, and J. Flint QTL analysis of multiple behavioral measures of anxiety in mice Behav Gen 34 2004 267 293 (Pubitemid 38437623)
35. S. Hogg A review of the validity and variability of the elevated plus-maze as an animal model of anxiety Pharmacol Biochem Behav 54 1996 21 30 (Pubitemid 26146661)
36. A) receptors: mechanism and site of action J Pharmacol Exp Therap 298 2001 986 995 (Pubitemid 32761913)
37. D.C. Llaneza, and C.A. Frye Progestogens and estrogen influence impulsive burying and avoidant freezing behavior of naturally cycling and ovariectomized rats Pharmacol Biochem Behav 93 2009 337 342
38. J.S. Lonstein Reduced anxiety in postpartum rats requires recent physical interactions with pups, but is independent of suckling and peripheral sources of hormones Horm Behav 47 2005 241 255 (Pubitemid 40222731)
39. J.S. Lonstein Regulation of anxiety during the postpartum period Front Neuroendocrinol 28 2007 115 141 (Pubitemid 47031314)
40. J.S. Lonstein, and S.M. Miller Infant touch, neurochemistry, and postpartum anxiety R.S. Bridges, The parental brain 2008 Academic Press 145 173
41. D. Maestripieri, and F.R. D'Amato Anxiety and maternal aggression in house mice (Mus musculus): a look at interindividual variability J Comp Psychol 105 1991 295 301
42. F.K. Marcondes, K.J. Miguel, L.L. Melo, and R.C. Spadari-Bratfisch Estrous cycle influences the response of female rats in the elevated plus-maze test Physiol Behav 74 2001 435 440 (Pubitemid 34076588)
43. C. Mathis, S.M. Paul, and J.N. Crawley Characterization of benzodiazepine-sensitive behaviors in the A/J and C57BL/6J inbred strains of mice Behav Genet 24 1994 171 180 (Pubitemid 24104851)
44. B.A. McCool, and A. Chappell Strychnine and taurine modulation of amygdala-associated anxiety-like behavior is 'state' dependent Behav Brain Res 178 2007 70 81 (Pubitemid 46240341)
45. L.M. McDonald, W.F. Sheppard, S.M. Staveley, B. Sohal, F.D. Tattersall, and P.H. Hutson Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats Psychopharmacology 197 2008 591 600
46. E.S. Mezzacappa, A.Y. Tu, and M.M. Myers Lactation and weaning effects on physiological and behavioral response to stressors Physiol Behav 78 2003 1 9 (Pubitemid 36110546)
47. M.J. Millan The neurobiology and control of anxious states Prog Neurobiol 70 2003 83 244 (Pubitemid 37309295)
48. S.M. Miller, and J.S. Lonstein Lactation and ambient light level, but not the anxiogenic agent FG-7142, affect anxiety in the light-dark box test Society for Behavioral Neuroendocrinology Abstracts 2006
49. A receptor binding in the neural anxiety network of postpartum and non-postpartum laboratory rats Brain Res Bull 86 2011 60 64
50. S.M. Miller, C.C. Piasecki, M.F. Peabody, and J.S. Lonstein GABAA receptor antagonism in the ventrocaudal periaqueductal gray increases anxiety in the anxiety-resistant postpartum rat Pharmacol Biochem Behav 95 2010 457 465
51. S. Mora, N. Dussaubat, and G. Díaz-Véliz Effects of the estrous cycle and ovarian hormones on behavioral indices of anxiety in female rats Psychoneuroendocrinology 21 1996 609 620 (Pubitemid 27107341)
52. A receptor complex ligands in two models of anxiety J Neur Trans 104 1997 733 746 (Pubitemid 27474686)
53. I.D. Neumann Brain mechanisms underlying emotional alterations in the peripartum period in rats Depress Anx 17 2003 111 121 (Pubitemid 36644709)
54. I.D. Neumann, H.A. Johnstone, M. Hatzinger, G. Liebsch, M. Shipston, and J.A. Russell Attenuated neuroendocrine responses to emotional and physical stressors in pregnant rats involve adenohypophysial changes J Physiol 508 1998 289 300 (Pubitemid 28167589)
55. L.B. Nicolas, and E.P. Prinssen Social approach-avoidance behavior of a high-anxiety strain of rats: effects of benzodiazepine receptor ligands Psychopharmacology 184 2006 65 74 (Pubitemid 43005758)
56. K. Nosek, K. Dennis, B.M. Andrus, N. Ahmadiyeh, A.E. Baum, L.C. Solberg Woods, and E.E. Redei Context and strain-dependent behavioral response to stress Behav Brain Funct 4 2008 23
57. S. Pellow, and S.E. File Anxiolytic and anxiogenic drug effecst on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat Pharmacol Biochem Behav 24 1986 525 529 (Pubitemid 16145187)
58. O. Picazo, and A. Fernández-Guasti Changes in experimental anxiety during pregnancy and lactation Physiol Behav 54 1993 295 299 (Pubitemid 23211394)
59. G.A. Qureshi, S. Hansen, and P. Sodersten Offspring control of cerebrospinal fluid GABA concentrations in lactating rats Neurosci Lett 75 1987 85 88 (Pubitemid 17029962)
60. A. Ramos Animal models of anxiety: do I need multiple tests? Trends Pharmacol Sci 29 2008 493 498
61. A. Ramos, O. Berton, P. Mormède, and F. Chaouloff A multiple-test study of anxiety-related behaviours in six inbred rat strains Behav Brain Res 85 1997 57 69 (Pubitemid 27116150)
62. A. Rex, U. Sondern, J.P. Voigt, S. Franck, and H. Fink Strain differences in fear-motivated behavior of rats Pharmacol Biochem Behav 54 1996 107 111 (Pubitemid 26143096)
63. R.J. Rodgers, and J.K. Shepherd Influence of prior maze experience on behaviour and response to diazepam in the elevated plus-maze and light/dark tests of anxiety in mice Psychopharmacology 113 1993 237 242 (Pubitemid 24001999)
64. U. Schmitt, and C. Hiemke Strain differences in open-field and elevated plus-maze behavior of rats without and with pretest handling Pharmacol Biochem Behav 59 1998 807 811 (Pubitemid 28237890)
65. J.D. Shepard, and D.A. Myers Strain differences in anxiety-like behavior: association with corticotropin-releasing factor Behav Brain Res 186 2008 239 245 (Pubitemid 350122758)
66. C.D. Smith, and J.S. Lonstein Contact with infants modulates anxiety-generated c-fos activity in the brains of postpartum rats Behav Brain Res 190 2008 193 200
67. J.M. Stern Somatosensation and maternal care in Norway rats J.S. Rosenblatt, C.T. Snowden, Parental care: evolution, mechanisms, and adaptive significance. Advances in the study of behavior Vol 25 1996 Academic San Diego 243 294 (Pubitemid 126141357)
68. J.M. Stern, L. Goldman, and S. Levine Pituitary-adrenal responsiveness during lactation in rats Neuroendocrinology 12 1973 179 191
69. D. Toufexis Region- and sex-specific modulation of anxiety behaviours in the rat J Neuroendocrinol 19 2007 461 473 (Pubitemid 46774038)
70. D.J. Toufexis, J. Rochford, and C.D. Walker Lactation-induced reduction in rats' acoustic startle is associated with changes in noradrenergic neurotransmission Behav Neurosci 113 1999 176 184 (Pubitemid 29138458)
71. T. Uehara, T. Sumiyoshi, T. Matsuoka, K. Tanaka, M. Tsunoda, and H. Itoh Enhancement of lactate metabolism in the basolateral amygdala by physical and psychological stress: role of benzodiazepine receptors Brain Res 1065 2005 86 91 (Pubitemid 41774630)
72. N. Violle, F. Balandras, Y. Le Roux, D. Desor, and H. Schroeder Variations in illumination, closed wall transparency and/or extramaze space influence both baseline anxiety and response to diazepam in the rat elevated plus-maze Behav Brain Res 203 2009 35 42
73. M.R. Zarrindast, P. Rostami, and M. Sadeghi-Hariri GABAA but not GABAB receptor stimulation induces antianxiety profile in rats Pharmacol Biochem Behav 69 2001 9 15 (Pubitemid 32566240)
74. M. Zienowicz, A. Wisłowska-Stanek, M. Lehner, E. Taracha, and A. Skórzewska Fluoxetine attenuates the effects of pentylenetetrazol on rat freezing behavior and c-Fos expression in the dorsomedial periaqueductal gray Neurosci Lett 414 2007 252 256
75. M.J. Zuluaga, D. Agrati, M. Pereira, N. Uriarte, A. Fernandez-Guasti, and A. Ferreira Experimental anxiety in the black and white model in cycling, pregnant and lactating rats Physiol Behav 84 2005 279 286 (Pubitemid 40222722)