Mycobacterium tuberculosis lineage influences innate immune response and virulence and is associated with distinct cell envelope lipid profiles

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Krishnan, Nitya ^a   Malaga, Wladimir ^b,c   Constant, Patricia ^b,c   Caws, Maxine ^d   Thi Hoang Chau, Tran ^e   Salmons, Jenifer ^a   Thi Ngoc Lan, Nguyen ^f   Bang, Nguyen Duc ^f   Daffé, Mamadou ^b,c   Young, Douglas B ^a,g   Robertson, Brian D ^a   Guilhot, Christophe ^b,c   Thwaites, Guy E ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^c UNIVERSITÉ DE TOULOUSE   (France)

^d OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^e UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^f Pham Ngoc Thach Hospital for Tuberculosis and Lung Disease   (Viet Nam)

^g NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; MEMBRANE LIPID; PHENOLPHTHIOCEROL DIMYCOCEROSATE; PHTHIOCEROL DIMYCOCEROSATE; PHTHIODIOLONE DIMYCOCEROSATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; GLYCOLIPID; LIPID Y;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CELL WALL; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; HOST PATHOGEN INTERACTION; INNATE IMMUNITY; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; STRAIN DIFFERENCE; THIN LAYER CHROMATOGRAPHY; TUBERCULOSIS; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD; CELL WALL; CYTOLOGY; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; LIPID METABOLISM; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PHENOTYPE; PHYLOGENY; SPECIES DIFFERENCE; SPLEEN;

BACTERIA (MICROORGANISMS); MUS; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; BLOOD; CELL WALL; DENDRITIC CELLS; FEMALE; GLYCOLIPIDS; HUMANS; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-1BETA; LIPID METABOLISM; MACROPHAGES; MICE; MICE, INBRED BALB C; MYCOBACTERIUM TUBERCULOSIS; PHENOTYPE; PHYLOGENY; SPECIES SPECIFICITY; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80052530215     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023870     Document Type: Article

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