Gamma-secretase inhibitor, a potential target therapy for MUC2-positive colorectal carcinoma

Neoplasma

Volumn 58, Issue 4, 2011, Pages 343-347

  Bu, X ^a   Li, N ^a   Tian, X ^a   Huang, P ^a  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

Author keywords

Cancer; Colorectum; Invasion; Notch signaling; Proliferation

Indexed keywords

GAMMA SECRETASE INHIBITOR; MUCIN 2; NOTCH RECEPTOR; TRANSCRIPTION FACTOR HES 1; ANTINEOPLASTIC AGENT; DIPEPTIDE; ENZYME INHIBITOR; MUC2 PROTEIN, HUMAN; N (N (3,5 DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT BUTYL ESTER; N-(N-(3,5-DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT-BUTYL ESTER; SECRETASE;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INVASION; CELL LINE; CELL PROLIFERATION; COLORECTAL CANCER; COLORECTAL CARCINOMA; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULARLY TARGETED THERAPY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; CELL MOTION; COLORECTAL TUMOR; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; TUMOR CELL LINE; WESTERN BLOTTING;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DIPEPTIDES; ENZYME INHIBITORS; HUMANS; MUCIN-2; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 80052523313     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: 10.4149/neo_2011_04_343     Document Type: Article

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