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Volumn 25, Issue 17, 2011, Pages 1871-1880

The microenvironment patterns the pluripotent mouse epiblast through paracrine furin and Pace4 proteolytic activities

Author keywords

Furin; Gastrulation; Microenvironment; Nodal; Progenitor cells; Proprotein convertases

Indexed keywords

FURIN; PACE4 PROTEIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 80052504025     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.16738711     Document Type: Article
Times cited : (39)

References (51)
  • 1
    • 0037066315 scopus 로고    scopus 로고
    • The ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation
    • Anderson ED, Molloy SS, Jean F, Fei H, Shimamura S, Thomas G. 2002. The ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation. J Biol Chem 277: 12879-12890.
    • (2002) J Biol Chem , vol.277 , pp. 12879-12890
    • Anderson, E.D.1    Molloy, S.S.2    Jean, F.3    Fei, H.4    Shimamura, S.5    Thomas, G.6
  • 2
    • 58849097959 scopus 로고    scopus 로고
    • Making a commitment: Cell lineage allocation and axis patterning in the early mouse embryo
    • Arnold SJ, Robertson EJ. 2009. Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. Nat Rev Mol Cell Biol 10: 91-103.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 91-103
    • Arnold, S.J.1    Robertson, E.J.2
  • 5
    • 14044273683 scopus 로고    scopus 로고
    • XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFb proteins in Xenopus development
    • Birsoy B, Berg L, Williams PH, Smith JC, Wylie CC, Christian JL, Heasman J. 2005. XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFb proteins in Xenopus development. Development 132: 591-602.
    • (2005) Development , vol.132 , pp. 591-602
    • Birsoy, B.1    Berg, L.2    Williams, P.H.3    Smith, J.C.4    Wylie, C.C.5    Christian, J.L.6    Heasman, J.7
  • 9
    • 33745256758 scopus 로고    scopus 로고
    • Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo
    • Camus A, Perea-Gomez A, Moreau A, Collignon J. 2006. Absence of Nodal signaling promotes precocious neural differentiation in the mouse embryo. Dev Biol 295: 743-755.
    • (2006) Dev Biol , vol.295 , pp. 743-755
    • Camus, A.1    Perea-Gomez, A.2    Moreau, A.3    Collignon, J.4
  • 10
    • 36549057057 scopus 로고    scopus 로고
    • Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation
    • Chang C, Harland RM. 2007. Neural induction requires continued suppression of both Smad1 and Smad2 signals during gastrulation. Development 134: 3861-3872.
    • (2007) Development , vol.134 , pp. 3861-3872
    • Chang, C.1    Harland, R.M.2
  • 11
    • 0035978752 scopus 로고    scopus 로고
    • The zebrafish Nodal signal Squint functions as a morphogen
    • Chen Y, Schier AF. 2001. The zebrafish Nodal signal Squint functions as a morphogen. Nature 411: 607-610.
    • (2001) Nature , vol.411 , pp. 607-610
    • Chen, Y.1    Schier, A.F.2
  • 13
    • 80052513996 scopus 로고    scopus 로고
    • Intracellular trafficking and signaling in development
    • doi: 10.3410/B1-59
    • Constam DB. 2009. Intracellular trafficking and signaling in development. F1000 Biol Rep 1: 59. doi: 10.3410/B1-59.
    • (2009) F1000 Biol Rep , vol.1 , pp. 59
    • Constam, D.B.1
  • 14
    • 0033545215 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein activities by pro domains and proprotein convertases
    • Constam DB, Robertson EJ. 1999. Regulation of bone morphogenetic protein activities by pro domains and proprotein convertases. J Cell Biol 144: 139-149.
    • (1999) J Cell Biol , vol.144 , pp. 139-149
    • Constam, D.B.1    Robertson, E.J.2
  • 15
    • 0034194471 scopus 로고    scopus 로고
    • SPC4/PACE4 regulates a TGFb signaling network during axis formation
    • Constam DB, Robertson EJ. 2000. SPC4/PACE4 regulates a TGFb signaling network during axis formation. Genes Dev 14: 1146-1155.
    • (2000) Genes Dev , vol.14 , pp. 1146-1155
    • Constam, D.B.1    Robertson, E.J.2
  • 18
    • 21044438948 scopus 로고    scopus 로고
    • Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning
    • Donnison M, Beaton A, Davey HW, Broadhurst R, L'Huillier P, Pfeffer PL. 2005. Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning. Development 132: 2299-2308.
    • (2005) Development , vol.132 , pp. 2299-2308
    • Donnison, M.1    Beaton, A.2    Davey, H.W.3    Broadhurst, R.4    L'huillier, P.5    Pfeffer, P.L.6
  • 20
    • 39949085446 scopus 로고    scopus 로고
    • Secretory cargo composition affects polarized secretion in MDCK epithelial cells
    • Fasciotto BH, Kuhn U, Cohn DV, Gorr SU. 2008. Secretory cargo composition affects polarized secretion in MDCK epithelial cells. Mol Cell Biochem 310: 67-75.
    • (2008) Mol Cell Biochem , vol.310 , pp. 67-75
    • Fasciotto, B.H.1    Kuhn, U.2    Cohn, D.V.3    Gorr, S.U.4
  • 21
    • 77949587674 scopus 로고    scopus 로고
    • Lentiviral vectors to probe and manipulate the Wnt signaling pathway
    • doi: 10.1371/journal.pone.0009370
    • Fuerer C, Nusse R. 2010. Lentiviral vectors to probe and manipulate the Wnt signaling pathway. PLoS ONE 5: e9370. doi: 10.1371/journal.pone.0009370.
    • (2010) PLoS ONE , vol.5
    • Fuerer, C.1    Nusse, R.2
  • 23
    • 34247139339 scopus 로고    scopus 로고
    • Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish
    • doi: 10.1186/1471-213X-7-22
    • Hagos EG, Dougan ST. 2007. Time-dependent patterning of the mesoderm and endoderm by Nodal signals in zebrafish. BMC Dev Biol 7: 22. doi: 10.1186/1471-213X-7-22.
    • (2007) BMC Dev Biol , vol.7 , pp. 22
    • Hagos, E.G.1    Dougan, S.T.2
  • 24
    • 0032544921 scopus 로고    scopus 로고
    • Development of a bicistronic vector driven by the human polypeptide chain elongation factor 1a promoter for creation of stable mammalian cell lines that express very high levels of recombinant proteins
    • Hobbs S, Jitrapakdee S, Wallace JC. 1998. Development of a bicistronic vector driven by the human polypeptide chain elongation factor 1a promoter for creation of stable mammalian cell lines that express very high levels of recombinant proteins. Biochem Biophys Res Commun 252: 368-372.
    • (1998) Biochem Biophys Res Commun , vol.252 , pp. 368-372
    • Hobbs, S.1    Jitrapakdee, S.2    Wallace, J.C.3
  • 25
    • 53249133091 scopus 로고    scopus 로고
    • The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages
    • Kwon GS, Viotti M, Hadjantonakis AK. 2008. The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. Dev Cell 15: 509-520.
    • (2008) Dev Cell , vol.15 , pp. 509-520
    • Kwon, G.S.1    Viotti, M.2    Hadjantonakis, A.K.3
  • 26
    • 0037352031 scopus 로고    scopus 로고
    • A highly efficient recombineering-based method for generating conditional knockout mutations
    • Liu P, Jenkins NA, Copeland NG. 2003. A highly efficient recombineering-based method for generating conditional knockout mutations. Genome Res 13: 476-484.
    • (2003) Genome Res , vol.13 , pp. 476-484
    • Liu, P.1    Jenkins, N.A.2    Copeland, N.G.3
  • 27
    • 2442646459 scopus 로고    scopus 로고
    • Sorting of furin in polarized epithelial and endothelial cells: Expression beyond the Golgi apparatus
    • Mayer G, Boileau G, Bendayan M. 2004. Sorting of furin in polarized epithelial and endothelial cells: expression beyond the Golgi apparatus. J Histochem Cytochem 52: 567-579.
    • (2004) J Histochem Cytochem , vol.52 , pp. 567-579
    • Mayer, G.1    Boileau, G.2    Bendayan, M.3
  • 28
    • 38349112617 scopus 로고    scopus 로고
    • The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates
    • Mayer G, Hamelin J, Asselin MC, Pasquato A, Marcinkiewicz E, Tang M, Tabibzadeh S, Seidah NG. 2008. The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates. J Biol Chem 283: 2373-2384.
    • (2008) J Biol Chem , vol.283 , pp. 2373-2384
    • Mayer, G.1    Hamelin, J.2    Asselin, M.C.3    Pasquato, A.4    Marcinkiewicz, E.5    Tang, M.6    Tabibzadeh, S.7    Seidah, N.G.8
  • 29
    • 0030019863 scopus 로고    scopus 로고
    • Heparan sulfate expression in polarized epithelial cells: The apical sorting of glypican (GPI-anchored proteoglycan) is inversely related to its heparan sulfate content
    • Mertens G, Van der Schueren B, van den Berghe H, David G. 1996. Heparan sulfate expression in polarized epithelial cells: the apical sorting of glypican (GPI-anchored proteoglycan) is inversely related to its heparan sulfate content. J Cell Biol 132: 487-497.
    • (1996) J Cell Biol , vol.132 , pp. 487-497
    • Mertens, G.1    van der Schueren, B.2    van den Berghe, H.3    David, G.4
  • 30
    • 77957730538 scopus 로고    scopus 로고
    • Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst
    • Mesnard D, Constam DB. 2010. Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst. J Cell Biol 191: 129-139.
    • (2010) J Cell Biol , vol.191 , pp. 129-139
    • Mesnard, D.1    Constam, D.B.2
  • 31
    • 33746435907 scopus 로고    scopus 로고
    • Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning
    • Mesnard D, Guzman-Ayala M, Constam DB. 2006. Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning. Development 133: 2497-2505.
    • (2006) Development , vol.133 , pp. 2497-2505
    • Mesnard, D.1    Guzman-Ayala, M.2    Constam, D.B.3
  • 32
    • 0033559118 scopus 로고    scopus 로고
    • Rapid modification of bacterial artificial chromosomes by ET-recombination
    • Muyrers JP, Zhang Y, Testa G, Stewart AF. 1999. Rapid modification of bacterial artificial chromosomes by ET-recombination. Nucleic Acids Res 27: 1555-1557.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1555-1557
    • Muyrers, J.P.1    Zhang, Y.2    Testa, G.3    Stewart, A.F.4
  • 33
    • 70350446976 scopus 로고    scopus 로고
    • Site-specific cleavage of BMP4 by furin, PC6 and PC7
    • Nelsen SM, Christian JL. 2009. Site-specific cleavage of BMP4 by furin, PC6 and PC7. J Biol Chem 284: 27157-27166.
    • (2009) J Biol Chem , vol.284 , pp. 27157-27166
    • Nelsen, S.M.1    Christian, J.L.2
  • 34
    • 0036638778 scopus 로고    scopus 로고
    • The Foxh1- dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo
    • Norris DP, Brennan J, Bikoff EK, Robertson EJ. 2002. The Foxh1- dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development 129: 3455-3468.
    • (2002) Development , vol.129 , pp. 3455-3468
    • Norris, D.P.1    Brennan, J.2    Bikoff, E.K.3    Robertson, E.J.4
  • 35
    • 27644458702 scopus 로고    scopus 로고
    • The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases
    • Nour N, Mayer G, Mort JS, Salvas A, Mbikay M, Morrison CJ, Overall CM, Seidah NG. 2005. The cysteine-rich domain of the secreted proprotein convertases PC5A and PACE4 functions as a cell surface anchor and interacts with tissue inhibitors of metalloproteinases. Mol Biol Cell 16: 5215-5226.
    • (2005) Mol Biol Cell , vol.16 , pp. 5215-5226
    • Nour, N.1    Mayer, G.2    Mort, J.S.3    Salvas, A.4    Mbikay, M.5    Morrison, C.J.6    Overall, C.M.7    Seidah, N.G.8
  • 38
    • 77957271489 scopus 로고    scopus 로고
    • Nodal morphogens
    • doi: 10.1101/cshperspect.a003459
    • Schier AF. 2009. Nodal morphogens. Cold Spring Harb Perspect Biol 1: a003459. doi: 10.1101/cshperspect.a003459.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Schier, A.F.1
  • 40
    • 0032913573 scopus 로고    scopus 로고
    • Basolateral sorting of furin in MDCK cells requires a phenylalanine-isoleucine motif together with an acidic amino acid cluster
    • Simmen T, Nobile M, Bonifacino JS, Hunziker W. 1999. Basolateral sorting of furin in MDCK cells requires a phenylalanine-isoleucine motif together with an acidic amino acid cluster. Mol Cell Biol 19: 3136-3144.
    • (1999) Mol Cell Biol , vol.19 , pp. 3136-3144
    • Simmen, T.1    Nobile, M.2    Bonifacino, J.S.3    Hunziker, W.4
  • 41
    • 0036167130 scopus 로고    scopus 로고
    • AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells
    • Simmen T, Honing S, Icking A, Tikkanen R, Hunziker W. 2002. AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells. Nat Cell Biol 4: 154-159.
    • (2002) Nat Cell Biol , vol.4 , pp. 154-159
    • Simmen, T.1    Honing, S.2    Icking, A.3    Tikkanen, R.4    Hunziker, W.5
  • 42
    • 33846022325 scopus 로고    scopus 로고
    • Analysis of furin ectodomain shedding in epididymal fluid of mammals: Demonstration that shedding of furin occurs in vivo
    • Thimon V, Belghazi M, Dacheux JL, Gatti JL. 2006. Analysis of furin ectodomain shedding in epididymal fluid of mammals: demonstration that shedding of furin occurs in vivo. Reproduction 132: 899-908.
    • (2006) Reproduction , vol.132 , pp. 899-908
    • Thimon, V.1    Belghazi, M.2    Dacheux, J.L.3    Gatti, J.L.4
  • 43
    • 0036791359 scopus 로고    scopus 로고
    • Furin at the cutting edge: From protein traffic to embryogenesis and disease
    • Thomas G. 2002. Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat Rev Mol Cell Biol 3: 753-766.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 753-766
    • Thomas, G.1
  • 44
    • 0037474206 scopus 로고    scopus 로고
    • Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix
    • Tsuji A, Sakurai K, Kiyokage E, Yamazaki T, Koide S, Toida K, Ishimura K, Matsuda Y. 2003. Secretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrix. Biochim Biophys Acta 1645: 95-104.
    • (2003) Biochim Biophys Acta , vol.1645 , pp. 95-104
    • Tsuji, A.1    Sakurai, K.2    Kiyokage, E.3    Yamazaki, T.4    Koide, S.5    Toida, K.6    Ishimura, K.7    Matsuda, Y.8
  • 45
    • 23844520920 scopus 로고    scopus 로고
    • A proteoglycan undergoes different modifications en route to the apical and basolateral surfaces of Madin-Darby canine kidney cells
    • Tveit H, Dick G, Skibeli V, Prydz K. 2005. A proteoglycan undergoes different modifications en route to the apical and basolateral surfaces of Madin-Darby canine kidney cells. J Biol Chem 280: 29596-29603.
    • (2005) J Biol Chem , vol.280 , pp. 29596-29603
    • Tveit, H.1    Dick, G.2    Skibeli, V.3    Prydz, K.4
  • 46
    • 0030932236 scopus 로고    scopus 로고
    • Nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation
    • Varlet I, Collignon J, Robertson EJ. 1997. nodal expression in the primitive endoderm is required for specification of the anterior axis during mouse gastrulation. Development 124: 1033-1044.
    • (1997) Development , vol.124 , pp. 1033-1044
    • Varlet, I.1    Collignon, J.2    Robertson, E.J.3
  • 47
    • 0027295514 scopus 로고
    • Characterization of a secreted form of human furin endoprotease
    • Vidricaire G, Denault JB, Leduc R. 1993. Characterization of a secreted form of human furin endoprotease. Biochem Biophys Res Commun 195: 1011-1018.
    • (1993) Biochem Biophys Res Commun , vol.195 , pp. 1011-1018
    • Vidricaire, G.1    Denault, J.B.2    Leduc, R.3
  • 48
    • 0037663390 scopus 로고    scopus 로고
    • Cell fate decisions within the mouse organizer are governed by graded Nodal signals
    • Vincent SD, Dunn NR, Hayashi S, Norris DP, Robertson EJ. 2003. Cell fate decisions within the mouse organizer are governed by graded Nodal signals. Genes Dev 17: 1646-1662.
    • (2003) Genes Dev , vol.17 , pp. 1646-1662
    • Vincent, S.D.1    Dunn, N.R.2    Hayashi, S.3    Norris, D.P.4    Robertson, E.J.5
  • 49
    • 0032549806 scopus 로고    scopus 로고
    • Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo
    • Waldrip WR, Bikoff EK, Hoodless PA, Wrana JL, Robertson EJ. 1998. Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo. Cell 92: 797-808.
    • (1998) Cell , vol.92 , pp. 797-808
    • Waldrip, W.R.1    Bikoff, E.K.2    Hoodless, P.A.3    Wrana, J.L.4    Robertson, E.J.5
  • 50
    • 0025606360 scopus 로고
    • Expression of a human proprotein processing enzyme: Correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site
    • Wise RJ, Barr PJ, Wong PA, Kiefer MC, Brake AJ, Kaufman RJ. 1990. Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site. Proc Natl Acad Sci 87: 9378-9382.
    • (1990) Proc Natl Acad Sci , vol.87 , pp. 9378-9382
    • Wise, R.J.1    Barr, P.J.2    Wong, P.A.3    Kiefer, M.C.4    Brake, A.J.5    Kaufman, R.J.6
  • 51
    • 77954055939 scopus 로고    scopus 로고
    • Shaping morphogen gradients by proteoglycans
    • doi: 10.1101/cshperspect.a002493
    • Yan D, Lin X. 2009. Shaping morphogen gradients by proteoglycans. Cold Spring Harb Perspect Biol 1: a002493. doi: 10.1101/cshperspect.a002493.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Yan, D.1    Lin, X.2


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