Negative regulation of cyclin D3 expression by trans-cription factor c-Ets1 in umbilical cord hematopoietic cells

Acta Pharmacologica Sinica

Volumn 32, Issue 9, 2011, Pages 1159-1164

  Meng, Fan Kai ^a   Sun, Han Ying ^a   Tan, Xi You ^a,b   Li, Chun Rui ^a   Zhou, Jian Feng ^a   Liu, Wen Li ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Shanghai Daopei Hospital   (China)

Author keywords

CD34+ cells; cell cycle; cyclins; gene regulation; hematopoietic stem cells; point mutation; Transcription factor c Ets1

Indexed keywords

CD34 ANTIGEN; CYCLIN D3; LUCIFERASE; TRANSCRIPTION FACTOR ETS 1;

ARTICLE; BINDING SITE; CELL PROLIFERATION; CONTROLLED STUDY; DELETION MUTANT; DOWN REGULATION; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; GENE ACTIVITY; GENE DELETION; GENE EXPRESSION; GENETIC TRANSFECTION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PROMOTER REGION; PROTEIN DOMAIN; REPORTER GENE; TRANSCRIPTION REGULATION; UMBILICAL CORD HEMATOPOIETIC STEM CELL; WILD TYPE;

ANTIGENS, CD3; BINDING SITES; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D3; FETAL BLOOD; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; HUMANS; POINT MUTATION; PROTO-ONCOGENE PROTEIN C-ETS-1;

EID: 80052492215     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2011.41     Document Type: Article

References (18)

1. Jude CD, Gaudet JJ, Speck NA, Ernst P. Leukemia and hematopoietic stem cells: balancing proliferation and quiescence. Cell Cycle 2008; 7: 586-91 (Pubitemid 351506325)
2. Della Ragione F, Borriello A, Mastropietro S, Della Pietra V, Monno F, Gabutti V, et al. Expression of G1-phase cell cycle genes during hematopoietic lineage. Biochem Biophys Res Commun 1997; 231: 73-6 (Pubitemid 27212111)
3. Ma Y, Yuan J, Huang M, Jove R, Cress WD. Regulation of the cyclin D3 promoter by E2F1. J Biol Chem 2003; 278: 16770-6 (Pubitemid 36799544)
4. Masamha CP, Benbrook DM. Cyclin D1 degradation is sufficient to nduce G1 cell cycle arrest despite constitutive expression of cyclin E2 in ovarian cancer cells. Cancer Res 2009; 69: 6565-72
5. Kozar K, Ciemerych MA, Rebel VI, Shigematsu H, Zagozdzon A Sicinska E, et al. Mouse development and cell proliferation in the absence of D-cyclins. Cell 2004; 118: 477-91 (Pubitemid 39485667)
6. Ando K, Ajchenbaum-Cymbalista F, Griffin JD. Regulation of G1/S transition by cyclins D2 and D3 in hematopoietic cells. Proc Natl Acad Sci U S A 1993; 90: 9571-5 (Pubitemid 23315827)
7. Dittmer J. The biology of the Ets1 proto-oncogene. Mol Cancer 2003; 2 29
8. Eyquem S, Chemin K, Fasseu M, Chopin M, Sigaux F, Cumano A, et al. The development of early and mature B cells is impaired in mice defcient for the Ets-1 transcription factor. Eur J Immunol 2004; 34 3187-96 (Pubitemid 39549397)
9. Jackers P, Szalai G, Moussa O, Watson DK. Ets-dependent regulation of target gene expression during megakaryopoiesis. J Biol Chem 2004; 279: 52183-90 (Pubitemid 39656592)
10. Marziali G, Perrotti E, Ilari R, Lulli V, Coccia EM, Mazzeo S. Role of Ets-1 in erythroid differentiation. Blood Cells Mol Dis 2002; 29: 553-61
11. Lulli V, Romania P, Riccioni R, Boe A, Lo-Coco F, Testa U, et al. Transcriptional silencing of the ETS1 oncogene contributes to human granulocytic differentiation. Haematologica 2010; 95: 1633-41
12. Lulli V, Romania P, Morsilli O, Gabbianelli M, Pagliuca A, Mazzeo S, et al. Overexpression of Ets-1 in human hematopoietic progenitor cells blocks erythroid and promotes megakaryocytic differentiation. Cel Death Differ 2006; 13: 1064-74 (Pubitemid 43905588)
13. Lee MW, Jang IK, Yoo KH, Sung KW, Koo HH. Stem and progenitor cells in human umbilical cord blood. Int J Hematol 2010; 92: 45-51.
14. Kast C, Wang M, Whiteway M. The ERK/MAPK pathway regulates the activity of the human tissue factor pathway inhibitor-2 promoter. J Bio Chem 2003; 278: 6787-94 (Pubitemid 36800667)
15. Makaula S, Adam T, Essop MF. Upstream stimulatory factor 1 transactivates the human gene promoter of the cardiac isoform of acetyl-Co A carboxylase. Arch Biochem Biophys 2006; 446: 91-100. (Pubitemid 43162396)
16. Kanda S, Shiroi A, Ouji Y, Birumachi J, Ueda S, Fukui H, et al. In vitro differentiation of hepatocyte-like cells from embryonic stem cells promoted by gene transfer of hepatocyte nuclear factor 3 beta Hepatol Res 2003; 26: 225-31 (Pubitemid 36927197)
17. Nesbit CE, Tersak JM, Prochownik EV. MYC oncogenes and human neoplastic disease. Oncogene 1999; 18: 3004-16 (Pubitemid 29276540)
18. Hahm K, Ernst P, Lo K, Kim GS, Turck C, Smale ST. The lymphoid transcription factor Ly F-1 is encoded by specifc, alternatively spliced m RNAs derived from the Ikaros gene. Mol Cell Biol 1994; 14: 7111-23 (Pubitemid 24326375)