Monoclonal antibodies to hyphal exoantigens derived from the opportunistic pathogen Aspergillus terreus

Clinical and Vaccine Immunology

Volumn 18, Issue 9, 2011, Pages 1568-1576

  Nayak, Ajay P ^a,b   Green, Brett J ^a   Janotka, Erika ^a   Hettick, Justin M ^a   Friend, Sherri ^a   Vesper, Steve J ^c   Schmechel, Detlef ^a   Beezhold, Donald H ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CYTOSOL AMINOPEPTIDASE; DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE V; EPITOPE; FUNGAL EXTRACT; HYPHAL EXOANTIGEN; IMMUNOGLOBULIN G1 ANTIBODY; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; ASPERGILLUS TERREUS; CELL STRUCTURE; CONFOCAL LASER MICROSCOPY; CONIDIUM; CONTROLLED STUDY; CROSS REACTION; CYTOPLASM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FUNGUS CULTURE; FUNGUS GROWTH; FUNGUS HYPHAE; IMMUNOLOCALIZATION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEOMICS; ROOM TEMPERATURE; SERODIAGNOSIS; THERMAL STIMULATION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, FUNGAL; ANTIBODIES, MONOCLONAL; ANTIGENS, FUNGAL; ASPERGILLOSIS; ASPERGILLUS; DIPEPTIDYL-PEPTIDASES AND TRIPEPTIDYL-PEPTIDASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; HYPHAE; IMMUNOPRECIPITATION; LEUCYL AMINOPEPTIDASE; MICE; MICROSCOPY, CONFOCAL; OPPORTUNISTIC INFECTIONS; PROTEOMICS; RABBITS; SPECIES SPECIFICITY;

EID: 80052470869     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.05163-11     Document Type: Article

References (74)

1. Al-Fattani, M. A., and L. J. Douglas. 2006. Biofilm matrix of Candida albicans and Candida tropicalis: Chemical composition and role in drug resistance. J. Med. Microbiol. 55:999-1008. (Pubitemid 44215557)
2. Atalla, M. M., N. M. Hassanein, A. A. El-Beih, and Y. A. Youssef. 2003. Mycotoxin production in wheat grains by different aspergilli in relation to different relative humidities and storage periods. Nahrung 47:6-10. (Pubitemid 37372057)
3. Baddley, J. W., P. G. Pappas, A. C. Smith, and S. A. Moser. 2003. Epidemiology of Aspergillus terreus at a university hospital. J. Clin. Microbiol. 41:5525-5529. (Pubitemid 37543239)
4. Balajee, S. A. 2009. Aspergillus terreus complex. Med. Mycol. 47(Suppl. 1): S42-S46.
5. Balajee, S. A., et al. 2009. Aspergillus alabamensis, a new clinically relevant species in the section Terrei. Eukaryot. Cell 8:713-722.
6. Balajee, S. A., et al. 2009. Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network (TRANSNET). J. Clin. Microbiol. 47:3138-3141.
7. Barrios-Gonzalez, J., and R. U. Miranda. 2010. Biotechnological production and applications of statins. Appl. Microbiol. Biotechnol. 85:869-883.
8. Beauvais, A., et al. 1997. Biochemical and antigenic characterization of a new dipeptidyl-peptidase isolated from Aspergillus fumigatus. J. Biol. Chem. 272: 6238-6244. (Pubitemid 27118095)
9. Bendtsen, J. D., H. Nielsen, G. Von Heijne, and S. Brunak. 2004. Improved prediction of signal peptides: SignalP 3.0. J. Mol. Biol. 340:783-795. (Pubitemid 38829638)
10. Berne, S., L. Lah, and K. Sepcic. 2009. Aegerolysins: Structure, function, and putative biological role. Protein Sci. 18:694-706.
11. Berry, D., A. Chmiel, and Z. Al Obaidi (ed.). 1977. Citric acid production by Aspergillus niger. Academic Press, London, United Kingdom.
12. Biguet, J., P. Tran van Ky, and S. Andrieu. 1967. Identification d'une activité chymotrypsique au niveau de fractions remarquables d'Aspergillus fumigatus. Répercussions sur le diagnostic immunologique de l'aspergillose. Rev. Immunol. Ther. Antimicrob. 31:317-328.
13. Blum, G., et al. 2008. Potential basis for amphotericin B resistance in Aspergillus terreus. Antimicrob. Agents Chemother. 52:1553-1555. (Pubitemid 351522034)
14. Bueno, D. J., J. O. Silva, and G. Oliver. 2001. Mycoflora in commercial pet foods. J. Food Prot. 64:741-743. (Pubitemid 32418089)
15. Caillot, D., et al. 2001. Increasing volume and changing characteristics of invasive pulmonary aspergillosis on sequential thoracic computed tomography scans in patients with neutropenia. J. Clin. Oncol. 19:253-259. (Pubitemid 32063503)
16. Cheetham, H. D. 1964. Subcutaneous infection due to Aspergillus terreus. J. Clin. Pathol. 17:251-253.
17. Chen, C. Y., and G. Seguin-Swartz. 2002. A rapid method for assessing the viability of fungal spores. Can. J. Plant Pathol. 24:230-232. (Pubitemid 34791900)
18. Chumpitazi, B. F. F., C. Pinel, B. Lebeau, P. Ambroise-Thomas, and R. Grillot. 2000. Aspergillus fumigatus antigen detection in sera from patients at risk for invasive aspergillosis. J. Clin. Microbiol. 38:438-443. (Pubitemid 30043338)
19. Chung, C. H., K. H. Ling, S. S. Tung, and T. C. Tung. 1971. Study on fungi of the stored unhulled rice of Taiwan. II. Aflatoxin B1-like compounds from the culture of Aspergillus genus. J. Formosan Med. Assoc. 70:258-266.
20. Dowdells, C., et al. 2010. Gluconic acid production by Aspergillus terreus. Lett. Appl. Microbiol. 51:252-257.
21. Fukuchi, Y. 2001. Interactions between Asp-hemolysin from Aspergillus fumigatus and blood plasma components. Yakugaku Zasshi. 121:423-432. (In Japanese.) (Pubitemid 32578411)
22. Garg, P., S. Mahesh, A. K. Bansal, U. Gopinathan, and G. N. Rao. 2003. Fungal infection of sutureless self-sealing incision for cataract surgery. Ophthalmology 110:2173-2177. (Pubitemid 37337855)
23. Gasteiger, E., et al. 2005. Protein identification and analysis tools on the ExPASy server, p. 571-607. In J. M. Walker (ed.), The proteomics protocols handbook. Humana Press, New York, NY.
24. Han, M. J., N. J. Kim, S. Y. Lee, and H. N. Chang. 2010. Extracellular proteome of Aspergillus terreus grown on different carbon sources. Curr. Genet. 56:369-382.
25. Haynes, K. A., J. P. Latge, and T. R. Rogers. 1990. Detection of Aspergillus antigens associated with invasive aspergillosis. J. Clin. Microbiol. 28:2040-2044. (Pubitemid 20260986)
26. Haynes, K. A., et al. 1996. Purification and characterization of a 93 kDa Aspergillus fumigatus antigen with diagnostic potential. J. Med. Vet. Mycol. 34:421-426. (Pubitemid 26420101)
27. Hill, T. W., and E. Kafer. 2001. Improved protocols for Aspergillus minimal medium: Trace element and minimal medium stock solutions. Fungal Genet. Newsl. 48:20-21.
28. Hilmioglu-Polat, S., et al. 2005. Non- Dermatophytic molds as agents of onychomycosis in Izmir, Turkey- A prospective study. Mycopathologia 160: 125-128. (Pubitemid 41361232)
29. Hope, W. W., and D. W. Denning. 2004. Invasive aspergillosis: Current and future challenges in diagnosis and therapy. Clin. Microbiol. Infect. 10:2-4. (Pubitemid 38128586)
30. Hope, W. W., T. J. Walsh, and D. W. Denning. 2005. Laboratory diagnosis of invasive aspergillosis. Lancet Infect. Dis. 5:609-622. (Pubitemid 41383906)
31. Horn, B. W. 2006. Relationship between soil densities of Aspergillus species and colonization of wounded peanut seeds. Can. J. Microbiol. 52:951-960. (Pubitemid 46144324)
32. Hughes, R. L. 1968. Microbiological degradation of paper, p. 281-290. In A. H. Walters and J. J. Elphick (ed.), Biodeterioration of materials. Elsevier Publishing Co. Ltd., New York, NY.
33. Iwen, P. C., M. E. Rupp, A. N. Langnas, E. C. Reed, and S. H. Hinrichs. 1998. Invasive pulmonary aspergillosis due to Aspergillus terreus: 12-year experience and review of the literature. Clin. Infect. Dis. 26:1092-1097. (Pubitemid 28215471)
34. Kobayashi, H., J. P. Debeaupuis, J. P. Bouchara, and J. P. Latge. 1993. An 88-kilodalton antigen secreted by Aspergillus fumigatus. Infect. Immun. 61: 4767-4771. (Pubitemid 23320533)
35. Latge, J. P. 1999. Aspergillus fumigatus and aspergillosis. Clin. Microbiol. Rev. 12:310-350.
36. Latge, J. P., et al. 1991. The 18-kilodalton antigen secreted by Aspergillus fumigatus. Infect. Immun. 59:2586-2594.
37. Loussert, C., et al. 2010. In vivo biofilm composition of Aspergillus fumigatus. Cell Microbiol. 12:405-410.
38. Marr, K. A., R. A. Carter, F. Crippa, A. Wald, and L. Corey. 2002. Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients. Clin. Infect. Dis. 34:909-917. (Pubitemid 34229758)
39. Miller, P. A., P. W. Trown, W. Fulmor, G. O. Morton, and J. Karliner. 1968. An epidithiapiperazinedione antiviral agent from Aspergillus terreus. Biochem. Biophys. Res. Commun. 33:219-221.
40. Monod, M., O. Jousson, and U. Reichard. 2009. Aspergillus fumigatus secreted proteases, p. 87-106. In J. P. Latge and W. J. Steinbach (ed.), Aspergillus fumigatus and aspergillosis. ASM Press, Washington, DC.
41. Moss, M. O. (ed.). 1977. Aspergillus mycotoxins. Academic Press, London, United Kingdom.
42. Muller, F. M. C., M. Seidler, and A. Beauvais. 2011. Aspergillus fumigatus biofilms in the clinical setting. Med. Mycol. 49:S96-S100.
43. Natesan, S., G. Abraham, M. Mathew, M. K. Lalitha, and C. N. Srinivasan. 2007. Secondary sternal Aspergillus osteomyelitis in a diabetic hemodialysis patient with previous allograft rejection. Hemodial Int. 11:403-405. (Pubitemid 47534863)
44. Nayak, A. P., et al. 2011a. Characterization of recombinant terrelysin, a hemolysin of Aspergillus terreus. Mycopathologia 171:23-34.
45. Nayak, A. P., et al. 2011b. Production and characterization of IgM monoclonal antibodies against hyphal antigens of Stachybotrys species. Hybridoma 30:29-36.
46. Nielsen, H., and A. Krogh. 1998. Prediction of signal peptides and signal anchors by a hidden Markov model, p. 122-130.In J. Glasgow et al. (ed.), Proceedings of the Sixth International Conference on Intelligent Systems for Molecular Biology. AAAI Press, Menlo Park, CA.
47. Osmani, S. A., D. B. Engle, J. H. Doonan, and N. R. Morris. 1988. Spindle formation and chromatin condensation in cells blocked at interphase by mutation of a negative cell cycle control gene. Cell 52:241-251.
48. Pore, R. S., and H. W. Larsh. 1967. Aleuriospore formation in four related Aspergillus species. Mycologia 59:318-325.
49. Rippon, J. W., D. N. Anderson, and M. Soo Hoo. 1974. Aspergillosis, comparative virulence, metabolic rate, growth rate and ubiquinone content of soil and human isolates of Aspergillus terreus. Sabouraudia 12:157-161.
50. Sakaguchi, O., H. Shimada, and K. Yokota. 1975. Proceedings: Purification and characteristics of hemolytic toxin from Aspergillus fumigatus. Jpn. J. Med. Sci. Biol. 28:328-331.
51. Schmechel, D., J. P. Simpson, D. Beezhold, and D. M. Lewis. 2006. The development of species-specific immunodiagnostics for Stachybotrys chartarum: The role of cross-reactivity. J. Immunol. Methods 309:150-159. (Pubitemid 43190811)
52. Segal, B. H. 2009. Aspergillosis. N. Engl. J. Med. 360:1870-1884.
53. Segal, B. H., and T. J. Walsh. 2006. Current approaches to diagnosis and treatment of invasive aspergillosis. Am. J. Respir. Crit. Care Med. 173:707-717.
54. Slunt, J. B., E. A. Taketomi, J. A. Woodfolk, M. L. Hayden, and T. A. Platts-Mills. 1996. The immune response to Trichophyton tonsurans: Distinct T cell cytokine profiles to a single protein among subjects with immediate and delayed hypersensitivity. J. Immunol. 157:5192-5197. (Pubitemid 126449604)
55. Speicher, K. D., O. Kolbas, S. Harper, and D. W. Speicher. 2000. Systematic analysis of peptide recoveries from in-gel digestions for protein identifications in proteome studies. J. Biomol. Tech. 11:74-86.
56. Steinbach, W. J., et al. 2004. Infections due to Aspergillus terreus: A multicenter retrospective analysis of 83 cases. Clin. Infect. Dis. 39:192-198. (Pubitemid 38971489)
57. Stone, K. L., and K. R. Williams. 2002. Enzymatic digestion of proteins in solution and in SDS-polyacrylamide gels, p. 511-521. In J. M. Walker (ed.), The protein protocols handbook, 2nd ed. Humana Press, Totowa, NJ.
58. Stynen, D., A. Goris, J. Sarfati, and J. P. Latge. 1995. A new sensitive sandwich enzyme-linked immunosorbent assay to detect galactofuran in patients with invasive aspergillosis. J. Clin. Microbiol. 33:497-500.
59. Thom, C., and M. B. Church. 1918. A. fumigatus, A. nidulans, A. terreus n. sp., and their allies. Am. J. Botany. 5:84-104.
60. Tiwari, S., S. M. Singh, and S. Jain. 1995. Chronic bilateral suppurative otitis media caused by Aspergillus terreus. Mycoses 38:297-300.
61. Van Emon, J. M., A. W. Reed, I. Yike, and S. J. Vesper. 2003. ELISA measurement of stachylysin in serum to quantify human exposures to the indoor mold Stachybotrys chartarum. J. Occup. Environ. Med. 45:582-591. (Pubitemid 36702674)
62. Varga, J., et al. 2005. Evolutionary relationships among Aspergillus terreus isolates and their relatives. Antonie Van Leeuwenhoek 88:141-150. (Pubitemid 41222941)
63. Verghese, S., R. Palani, N. Thirunavakarasu, T. Chellamma, and P. Pathipata. 2008. Peritonitis due to Aspergillus terreus in a patient undergoing continuous ambulatory peritoneal dialysis. Mycoses 51:174-176. (Pubitemid 351191119)
64. Vermout, S., A. Baldo, J. Tabart, B. Losson, and B. Mignon. 2008. Secreted dipeptidyl peptidases as potential virulence factors for Microsporum canis. FEMS Immunol. Med. Microbiol. 54:299-308.
65. Vesper, S. J., M. L. Magnuson, D. G. Dearborn, I. Yike, and R. A. Haugland. 2001. Initial characterization of the hemolysin stachylysin from Stachybotrys chartarum. Infect. Immun. 69:912-916. (Pubitemid 32109556)
66. Walsh, T. J., et al. 2003. Experimental pulmonary aspergillosis due to Aspergillus terreus: Pathogenesis and treatment of an emerging fungal pathogen resistant to amphotericin B. J. Infect. Dis. 188:305-319. (Pubitemid 36898165)
67. Woodfolk, J. A., J. B. Slunt, B. Deuell, M. L. Hayden, and T. A. Platts-Mills. 1996. Definition of a Trichophyton protein associated with delayed hypersensitivity in humans. Evidence for immediate (IgE and IgG4) and delayed hypersensitivity to a single protein. J. Immunol. 156:1695-1701. (Pubitemid 26065882)
68. Woodfolk, J. A., L. M. Wheatley, R. V. Piyasena, D. C. Benjamin, and T. A. Platts-Mills. 1998. Trichophyton antigens associated with IgE antibodies and delayed type hypersensitivity. Sequence homology to two families of serine proteinases. J. Biol. Chem. 273:29489-29496. (Pubitemid 28509954)
69. Xiang, X., C. Roghi, and N. R. Morris. 1995. Characterization and localization of the cytoplasmic dynein heavy chain in Aspergillus nidulans. Proc. Natl. Acad. Sci. U. S. A. 92:9890-9894.
70. Yano, S., S. Shishido, K. Kobayashi, H. Nakano, and Y. Kawasaki. 1999. Bronchocentric granulomatosis due to Aspergillus terreus in an immunocompetent and non-asthmatic woman. Respir. Med. 93:672-674. (Pubitemid 29476259)
71. Yokota, K., H. Shimada, A. Kamaguchi, and O. Sakaguchi. 1977. Studies on the toxin of Aspergillus fumigatus VII. Purification and some properties of hemolytic toxin (asp-hemolysin) from culture filtrates and mycelia. Microbiol. Immunol. 21:11-22. (Pubitemid 8084155)
72. Yuanjie, Z., D. Jingxia, W. Hai, C. Jianghan, and G. Julin. 2009. Primary cutaneous aspergillosis in a patient with cutaneous T-cell lymphoma. Mycoses 52:462-464.
73. Zaas, A. K., and B. D. Alexander. 2009. Invasive pulmonary aspergillosis, p. 293-300. In J. P. Latge and W. J. Steinbach (ed.), Aspergillus fumigatus and aspergillosis. ASM Press, Washington, DC.
74. Zhang, M., et al. 2004. Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV and HCV envelopes and influenza hemagglutinin. Glycobiology 14:1229-1246. (Pubitemid 39585357)