Linezolid in the treatment of methicillin-resistant staphylococcal post-neurosurgical meningitis: A series of 17 cases

Scandinavian Journal of Infectious Diseases

Volumn 43, Issue 10, 2011, Pages 757-764

  Sipahi, Oguz Resat ^a   Bardak, Selin ^a   Turhan, Tuncer ^b   Arda, Bilgin ^a   Pullukcu, Husnu ^a   Ruksen, Mete ^b   Aydemir, Sohret ^a   Dalbasti, Tayfun ^b   Yurtseven, Taskin ^b   Zileli, Mehmet ^b   Ulusoy, Sercan ^a  

^a EGE UNIVERSITY   (Turkey)

^b Department of Neurosurgery ^*  (Turkey)

Author keywords

Daptomycin; Glycopeptides; Oxazolidinones; Teicoplanin; Vancomycin

Indexed keywords

AMIKACIN; BRAIN PROTEIN; CEFEPIME; CEFTAZIDIME; CEFTIZOXIME; CEFTRIAXONE; DAPTOMYCIN; GLUCOSE; IMIPENEM; LINEZOLID; MEROPENEM; NETILMICIN; PIPERACILLIN PLUS TAZOBACTAM; RIFAMPICIN; TEICOPLANIN; VANCOMYCIN;

ACINETOBACTER BAUMANNII MENINGITIS; ACINETOBACTER BAUMANNII PNEUMONIA; ACINETOBACTER INFECTION; ADULT; AGED; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL MENINGITIS; BACTERIUM CULTURE; BLOOD TOXICITY; BRAIN HEMATOMA; CASE STUDY; CEREBROSPINAL FLUID CULTURE; CEREBROSPINAL FLUID LEVEL; CLINICAL ARTICLE; COAGULASE NEGATIVE STAPHYLOCOCCUS; DEMOGRAPHY; DISEASE PREDISPOSITION; DISEASE SEVERITY; DRUG EFFICACY; DRUG TREATMENT FAILURE; ENTEROBACTER CLOACAE; ENTEROBACTER CLOACAE MENINGITIS; ENTEROBACTERIACEAE INFECTION; FEMALE; GLUCOSE BRAIN LEVEL; HOSPITAL AQUIRED MENINGITIS; HOSPITAL INFECTION; HUMAN; LEUKOCYTOSIS; LIQUORRHEA; LIVER TOXICITY; MALE; MENINGITIS; METHICILLIN RESISTANT COAGULASE NEGATIVE STAPHYLOCOCCAL MENINGITIS; METHICILLIN RESISTANT COAGULASE NEGATIVE STAPHYLOCOCCUS; METHICILLIN RESISTANT COAGULASE NEGATIVE STAPHYLOCOCCUS MENINGITIS; METHICILLIN RESISTANT STAPHYLOCOCCAL MENINGITIS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; METHICILLIN RESISTANT STAPHYLOCOCCUS MENINGITIS; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; NEPHROTOXICITY; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PLEOCYTOSIS; PROTEIN CEREBROSPINAL FLUID LEVEL; PROVIDENCIA STUARTII MENINGITIS; PSEUDOMONAS AERUGINOSA MENINGITIS; PSEUDOMONAS INFECTION; PSEUDOMONAS PNEUMONIA; SHUNT INFECTION; SURVIVAL TIME; TREATMENT DURATION; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

ACETAMIDES; ADULT; ANTI-BACTERIAL AGENTS; CROSS INFECTION; FEMALE; HUMANS; MALE; MENINGITIS, BACTERIAL; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; NEUROSURGICAL PROCEDURES; OXAZOLIDINONES; POSTOPERATIVE COMPLICATIONS; PROSTHESIS-RELATED INFECTIONS; RETROSPECTIVE STUDIES; STAPHYLOCOCCAL INFECTIONS;

EID: 80052449722     PISSN: 00365548     EISSN: 16511980     Source Type: Journal    
DOI: 10.3109/00365548.2011.585177     Document Type: Article

References (25)

1. Arda B, Yamazhan T, Sipahi OR, Islekel S, Buke C, Ulusoy S. Meningitis due to methicillin-resistant Staphylococcus aureus (MRSA): review of 10 cases. Int J Antimicrob Agents 2005;25:414-8. (Pubitemid 40558774)
2. Huang CR, Lu CH, Wu JJ, Chang HW, Chien CC, Lei CB, et al. Coagulase-negative staphylococcal meningitis in adults: clinical characteristics and therapeutic outcomes. Infection 2005;33:56-60.
3. Palabiyikoglu I.,Tekeli E.,Cokca F.,Akan O.,Unal N.,Erberktas I.,et al. Nosocomial meningitis in a university hospital between 1993 and 2002. J Hosp Infect 2006; 62: 94-7. (Pubitemid 43103016)
4. Tunkel AR, van de Beek D, Scheld WM. Acute meningitis. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and practice of infectious diseases. 7th ed. Churchill Livingstone, Elsevier, New York; 2010. p. 1189-229.
5. Hardy KJ, Hawkey PM, Gao F, Oppenheim BA. Methicillin-resistant Staphylococcus aureus in the critically ill. Br J Anaesth 2004;92:121-30. (Pubitemid 38054659)
6. Moellering RC. Pharmacokinetics of vancomycin. J Antimi-crob Chemother 1984;14(Suppl D):43-52.
7. Quintilliani R, Cooper B W. Current concepts in the treatment of staphylococcal meningitis. J Antimicrob Chemother 1988;21:107-12.
8. Faella F, Pagliano P, Fusco U, Attanasio V, Conte M. Combined treatment with ceftriaxone and linezolid of pneumo-coccal meningitis: a case series including penicillin resistant strains. Clin Microbiol Infect 2006;12:391-4. (Pubitemid 43337531)
9. Kruse AJ, Peerdeman SM, Bet PM, Debets-Ossenkopp YJ. Successful treatment with linezolid and rifampicin of meningitis due to methicillin-resistant Staphylococcus epidermidis refractory to vancomycin treatment. Eur J Clin Microbiol Infect Dis 2006;25:135-7. (Pubitemid 43333680)
10. Ntziora F, Falagas ME. Linezolid for the treatment of patients with central nervous system infection. Ann Pharmacother 2007;41:296-308. (Pubitemid 46340060)
11. Arman D, Sari N, Ergüt-Sezer B, Ata N, Dizbay M, Hizel K, et al. A case of methicillin-sensitive Staphylococcus aureus (MSSA) meningitis-cerebritis treated with linezolid. Flora 2009;14:139-43.
12. Falagas ME, Manta KG, Ntziora F,Vardakas KZ.Linezolid for the treatment of patients with endocarditis: a systematic review of the published evidence. J Antimicrob Chemother 2006:58;273-80. (Pubitemid 44313381)
13. Villani P, Regazzi MB, Marubbi F, Viale P, Pagani L, Cristini F, et al. Cerebrospinal fluid linezolid concentrations in post-neurosurgical central nervous system infections. Antimicrob Agents Chemother 2002;46:936-7. (Pubitemid 34157696)
14. Viale P, Pagani L, Cristini F, Stefini R, Bergomi R, Colom-bini P, et al. Linezolid for the treatment of central nervous system infections in neurosurgical patients. Scand J Infect Dis 2002;34:456-9. (Pubitemid 34823442)
15. Garner JS, Jarvis WR, Emori TG, Horon TC, Hughes JM. CDC definitions for nosocomial infections. In: Olmsted RN, editor. APIC infection control and applied epidemiology: principles and practice. St Louis: Mosby; 1996. p. A1-20.
16. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: 19th informational supplement. M100-S19. Wayne, PA: CLSI; 2009.
17. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing: 20th informational supplement. M100-S20. Wayne, PA: CLSI; 2010.
18. Sipahi OR, Arda B, Yurtseven T, Sipahi H, Ozgiray E, Suntur BM, et al. Vancomycin versus teicoplanin in the therapy of experimental methicillin-resistant Staphylococcus aureus (MRSA) meningitis. Int J Antimicrob Agents 2005;26:412-5. (Pubitemid 41483473)
19. European Committee on Antimicrobial Susceptibility Testing (EUCAST). Clinical MIC breakpoints. Available at: http://www. eucast.org/clinical- breakpoints/(accessed 1 March 2011).
20. Samra Z, Ofer O, Shmuely H. Susceptibility of methicillin-resistant Staphylococcus aureus to vancomycin, teicoplanin, linezolid, pristinamycin, and other antibiotics. Isr Med Assoc J 2005;7:148-50. (Pubitemid 40424956)
21. Harland S, Tebss SE, Elliott TSJ. Evaluation of the in-vitro activity of the glycopeptide antibiotic LY 333328 in comparison with vancomycin and teicoplanin. J Antimicrob Chemother 1998;41:273-6. (Pubitemid 28083132)
22. Arda B, Sipahi OR, Yamazhan T, Tasbakan M, Pullukcu H, Tunger A, et al. Short-term effect of antibiotic control policy on the usage patterns and cost of antimicrobials, mortality, nosocomial infection rates and antibacterial resistance. J Infect 2007;55:41-8. (Pubitemid 46888080)
23. Calik S, Turhan T, Yurtseven T, Sipahi O, Buke C. Vancomycin versus linezolid in the therapy of experimental methicillin-resistant Staphylococcus aureus meningitis. Abstract P1023. Abstracts of the 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Helsinki, 2009.
24. Moise PA, Sakoulas G, Forrest A, Schentag JJ. Vancomycin in vitro bactericidal activity and its relationship to efficacy in clearance of methicillin-resistant Staphylococcus aureus bac-teremia. Antimicrob Agents Chemother 2007;51:2582-6. (Pubitemid 47047340)
25. Chaudhuri A, Martinez-Martin P, Kennedy PG, Andrew Seaton R, Portegies P, Bojar M, et al. EFNS guideline on the management of community-acquired bacterial meningitis: report of an EFNS Task Force on acute bacterial meningitis in older children and adults. Eur J Neurol 2008;15:649-59. (Pubitemid 351814425)