Cellular infiltration and cytokine expression correlate with fistulizing state in Crohn's disease

Clinical and Vaccine Immunology

Volumn 18, Issue 9, 2011, Pages 1416-1419

  Naser, Saleh A ^a   Romero, Claudia ^a   Urbina, Princess ^a   Naser, Najih ^b   Valentine, John ^c  

^a UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^b Division of Biomedical Research   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 12; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; B LYMPHOCYTE; CELL INFILTRATION; CELL SUBPOPULATION; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HELPER CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTESTINE FISTULA; LYMPHOCYTE DIFFERENTIATION; MALE; MOLECULAR PATHOLOGY; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

ADULT; AGED; CROHN DISEASE; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-12; INTESTINAL FISTULA; INTESTINAL MUCOSA; MACROPHAGES; MALE; MIDDLE AGED; T-LYMPHOCYTES, HELPER-INDUCER; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 80052431869     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.05095-11     Document Type: Article

References (17)

1. Amati, L., et al. 2003. Immune abnormalities and endotoxemia in patients with ulcerative colitis and in their first degree relatives: Attempts at neutralizing endotoxin-mediated effects. Curr. Pharm. Des. 9:1937-1945. (Pubitemid 37010098)
2. Braat, H., M. P. Peppelenbosch, and D. W. Hommes. 2003. Interleukin-10-based therapy for inflammatory bowel disease. Expert Opin. Biol. Ther. 3:725-731. (Pubitemid 36934972)
3. Cavaglieri, C. R., et al. 2003. Differential effects of short-chain fatty acids (SCFA) on proliferation and production of pro- and anti-inflammatory cytokines by cultured lymphocytes. Life Sci. 73:1683-1690. (Pubitemid 36859872)
4. Daig, R., et al. 1996. Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease. Gut 38:216-222.
5. Everhart, J. E. 1994. Digestive diseases in the United States: epidemiology and impact 1994. NIH publication no. 94-1447. NIH, Bethesda, MD.
6. Goerdt, S., et al.1999. Alternative versus classical activation of macrophages. Pathobiology 67:222-226. (Pubitemid 30135909)
7. Kmiec, Z. 1998. Cytokines in inflammatory bowel disease. Arch. Immunol. Ther. Exp. 46:143-155. (Pubitemid 28319262)
8. Mishina, D., P. Katsel, S. T. Brown, E. C. Gilberts, and R. J. Greenstein. 1996. On the etiology of Crohn's disease. Proc. Natl. Acad. Sci. U. S. A. 93:9816-9820.
9. Mitsuyama, K., et al. 1994. IL-8 is an important chemoattractant for neutrophils for ulcerative colitis and Crohn's disease. Clin. Exp. Immunol. 96:432-436. (Pubitemid 24224862)
10. Mohagheghpour, N., A. Van Vollenhoven, J. Goodman, and L. E. Bermudez. 2000. Interaction of Mycobacterium avium with human monocyte-derived dendritic cells. Infect. Immun. 68:5824-5829.
11. Monteleone, I., P. Vavassori, L. Biancone, G. Monteleone, and F. Pallone. 2002. Immunoregulation in the gut: Success and failures in human disease. Gut 50:60-64.
12. Pallone, F., and G. Monteleone. 1998. Interleukin-12 and Th1 responses in inflammatory bowel disease. Gut 43:735-736. (Pubitemid 28539644)
13. Sarsfield, P., D. B. Jones, and D. H. Wright. 1996. Accessory cells in Crohn's disease of the terminal ileum. Histopathology 28:213-219. (Pubitemid 26091912)
14. Savedra, R., Jr., et al. 1996. Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system. J. Immunol. 157:2549-2554.
15. Selby, W. S., G. Janossy, M. Bofill, and D. P. Jewell. 1984. Intestinal lymphocyte subpopulations in inflammatory bowel disease: An analysis by immunohistological and cell isolation techniques. Gut 25:32-40. (Pubitemid 14125744)
16. Silver, R. F., et al. 2003. Recruitment of antigen-specific Th1-like responses to the human lung following bronchoscopic segmental challenge with purified protein derivative of Mycobacterium tuberculosis. Am. J. Respir. Cell Mol. Biol. 29:117-123. (Pubitemid 36783323)
17. Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249:1431-1433.