Asphalt fume dermal carcinogenicity potential: II. Initiation-promotion assay of Type III built-up roofing asphalt

Regulatory Toxicology and Pharmacology

Volumn 61, Issue 1, 2011, Pages 17-22

  Freeman, James J ^a   Schreiner, Ceinwen A ^b   Beazley, S ^c   Burnett, Donald M ^d   Clark, Charles R ^e   Mahagaokar, Suneeta ^f   Parker, Craig M ^g   Stewart, Christopher W ^c   Swanson, Mark S ^g   Arp, Earl W ^h  

^a EXXONMOBIL UPSTREAM RESEARCH COMPANY   (United States)

^b C and C Consulting in Toxicology   (United States)

^c MPI RESEARCH   (United States)

^d BP Corporation ^*  (United States)

^e ConocoPhillips Company ^*  (United States)

^f SHELL OIL COMPANY   (United States)

^g Marathon Petroleum   (United States)

^h ASPHALT INSTITUTE   (United States)

Author keywords

Asphalt; Bitumen; Field matched fume; Fume condensate; Skin carcinogenicity; Skin irritation; Tumor initiation promotion; Type III BURA

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; ASPHALT; PHORBOL 13 ACETATE 12 MYRISTATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOASSAY; BODY WEIGHT; CARCINOGENICITY; CONTROLLED STUDY; EPIDERMIS HYPERPLASIA; FUME; GENOTOXICITY; HISTOPATHOLOGY; KERATOACANTHOMA; MALE; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN CARCINOGENESIS; SKIN INFLAMMATION; SKIN INJURY; SKIN IRRITATION; SKIN PAPILLOMA; TANK; TUMOR PROMOTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ADMINISTRATION, CUTANEOUS; AIR POLLUTANTS, OCCUPATIONAL; ANIMALS; BODY WEIGHT; CARCINOGENS; HYDROCARBONS; MALE; MICE; OCCUPATIONAL EXPOSURE; SKIN; SKIN DISEASES; SKIN NEOPLASMS; TETRADECANOYLPHORBOL ACETATE;

ANIMALIA; MUS;

EID: 80052401456     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2011.05.008     Document Type: Article

References (20)

1. Standard test method for determining carcinogenic potential of virgin base oils in metal working fluids (Designation: E 1687-04) 2004, American Society for Testing and Materials, ASTM, West Conshohocken, PA.
2. Clark, C.R., Burnett, Donald M., Parker, Craig M., Arp, Earl W., Swanson, Mark S., Minsavage, Gary D., Kriech, Anthony J., Osborn, Linda V., Freeman, James J., Barter, Robert A., Newton, Paul E., Stewart, Christopher W., accepted for publication. Asphalt fume dermal carcinogenicity potential: I. Dermal carcinogenicity evaluation of asphalt (bitumen) fume condensates. Regul. Toxicol. Pharmacol.
3. CRC Handbook of Toxicology 1995, 47. CRC Press, Boca Raton, FL. M.J. Derelanko, M.A. Hollinger (Eds.).
4. Freeman J.J., McKee R.H. The objectives and goals of dermal carcinogenicity testing of petroleum liquids. Health Risk Assessment. Dermal and Inhalation Exposure and Absorption of Toxicants 1993, 283-289. CRC Press, Boca Raton FL. R.G.M. Wang, J.B. Knaak, H.I. Maibach (Eds.).
5. Freeman J.J., McKee R.H., Phillips R.D., Plutnick R.T., Scala R.A., Ackerman L.J. A 90-day toxicity study of the effects of petroleum middle distillates on the skin of C3H mice. Toxicol. Ind. Health 1990, 6:475-491.
6. Fuhst R., Creutzenberg O., Ernst H., Hansen T., Pohlmann G., Preiss A., Rittinghausen S. 24months inhalation carcinogenicity study of bitumen fumes in Wistar (WU) rats. J. Occup. Environ. Hyg. 2007, 4(S1):20-43.
7. Kriech A.J., Kurek J.T., Osborn L.V., Wissel H.L., Blackburn G.R. Evaluation of worker exposure to paving fumes using traditional and non-traditional techniques. A. Ind. Hyg. Assoc. J. 2002, 63:628-635.
8. Kriech A.J., Osborn L.V., Wissel H.L., Redman A.P., Smith L.A., Dobbs T.E. Generation of bitumen fumes using two fume generation protocols and comparison to worker industrial hygiene exposures. J. Occup. Environ. Hygiene 2007, 4(1):6-19.
9. Nessel C.S., Priston R.A.J., McKee R.H., Cruzan G., Riley A.J., Hagemann R., Plutnick R.T., Simpson B.J. A comprehensive evaluation of the mechanism of skin tumorigenesis by straight run and cracked petroleum middle distillates. Toxicol. Sci. 1998, 44:22-32.
10. Nessel C.S., Freeman J.J., Forgash R.C., McKee R.H. The role of dermal irritation in the skin tumor promoting activity of petroleum middle distillates. Toxicol. Sci. 1999, 49:48-55.
11. Niemeier R.W., Thayer P.S., Menzies K.T., Von Thuna P., Moss C.E., Burg J. A comparison of the skin carcinogenicity of condensed roofing asphalt and coal tar pitch fumes. In Polynuclear Aromatic Hydrocarbons: A Decade of Progress. Tenth International Symposium 1988, Battelle Press, Columbus, Ohio, pp 609-647.
12. Olsson A.H., Kromhout H., Agostini M., Hansen J., Lassen C.F., Johansen C., Kjaerheim K., Langard S., Stucker I., Ahrens W., Behrens T., Lindbohm M.-L., Heikkila P., Heederik D., Portengen L., Shaham J., Ferro G., de Vocht F., Burstyn I., Boffetta P. A case-control study of lung cancer nested in a cohort of European asphalt workers. Environ. Health Perspect. 2010, 118(10):1418-1424.
13. Peigorsch W., Bailer J. Statistics for Environmental Biology and Toxicology 1997, Chapman and Hall, pp. 234-241.
14. Przygoda R.T., Freeman J.J., Katz S., McKee R.H. Increased frequency of resistance to terminal differentiation in C3H mouse cells produced by genotoxic but not nongenotoxic carcinogens. Fundam. Appl. Toxicol 1994, 23:261-267.
15. Reinke G.M., Swanson M., Paustenbach D., Beach J. Chemical and mutagenic properties of asphalt fume condensate generated under laboratory and field conditions. Mutat. Res. 2000, 469:41-50.
16. Sivak A., Niemeier R., Lynch D., Beltis K., Simon S., Salomon R., Latta R., Belinky B., Menzies K., Lunsford A., Cooper C., Ross A., Bruner R. Skin carcinogenicity of condensed asphalt roofing fumes and their fractions following dermal application to mice. Cancer Lett. 1997, 117:113-123.
17. Snedecor G.W., Cochran W.G. Statistical Methods 1989, Iowa State University Press, Iowa. 8th ed.
18. Steel R.G.D., Torrie J.H. Principles and Procedures of Statistics. A biometrical approach 1980, McGraw-Hill, New York.
19. Watkins D.K., Chiazze L., Fryar C.D., Fayerweather W. A case control study of lung cancer and non-malignant respiratory disease among employees in asphalt roofing manufacturing and asphalt production. J. Occup. Environ. Med. 2002, 44:551-558.
20. Zar J.H. Biostatistical Analysis 1999, Prentice Hall, New Jersey. fourth ed.