A comprehensive evaluation of the mechanism of skin tumorigenesis by straight-run and cracked petroleum middle distillates

Toxicological Sciences

Volumn 44, Issue 1, 1998, Pages 22-31

  Nessel, Craig S ^a   Priston, Robert A J ^b   McKee, Richard H ^a   Cruzan, George ^a,f   Riley, Anthony J ^c   Hagemann, Randi ^d   Plutnick, Robert T ^a   Simpson, Barry J ^e  

^a EXXONMOBIL UPSTREAM RESEARCH COMPANY   (United States)

^b Shell Chemicals Europe Limited   (United Kingdom)

^c BP EXPLORATION   (United Kingdom)

^d STATOIL   (Norway)

^e Refinery Technology Support Group   (Belgium)

^f Tox Works   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KEROSENE; MINERAL OIL; PETROLEUM DERIVATIVE; POLYCYCLIC AROMATIC COMPOUND;

AMES TEST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL REGENERATION; CONTROLLED STUDY; GENOTOXICITY; MALE; MOUSE; NONHUMAN; SKIN ABSORPTION; SKIN CARCINOGENESIS; SKIN IRRITATION; SKIN PENETRATION; SKIN TUMOR;

EID: 0031846527     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1006/toxs.1998.2477     Document Type: Article

References (25)

1. Biles, R. W., McKee, R. H., Lewis, S. C., Scala, R. A., and DePass, L. R. (1988). Dermal carcinogenic activity of petroleum-derived middle distillate fuels. Toxicology 53, 301-314.
2. Bingham, E., Trosset, R. P., and Warshawsky, D. (1980). Carcinogenic potential of petroleum hydrocarbons: A critical review of the literature. J. Environ. Pathol. Toxicol. 3, 483-563.
3. Blackburn, G. R., Deitch, R. A., Schreiner, C. A., and Mackerer, C. R. (1986). Predicting carcinogenicity of petroleum distillation fractions using a modified Salmonella mutagenicity assay. Cell Biol. Toxicol. 2, 63-84.
4. Blackburn, G. R., Roy, T. A., Deitch, R. A., Dooley, J. F., Schreiner, C. A., and Mackerer, C. R. (1984). "Correlation of in Vitro Mutagenicity with Dermal Carcinogenicity for Complex, Petroleum-Derived Materials." Presented at Symposium Carcinogenese Cutanee, Rouen, France, June 18-22, 1984.
5. Bradley, J. V. (1968). In Distribution Free Statistical Tests, pp. 195-203. Prentice Hall, Englewood Cliffs, NJ.
6. Clark, C. R., Walter, M. K., Ferguson, P. W., and Katchen, M. (1988). Comparative dermal carcinogenesis of shale and petroleum-derived distillates. Toxicol. Ind. Health 4, 11-22.
7. Deininger, G., Jungen, H., and Wenzel-Hartung, R. P. (1991). "Middle Distillates; Analytical Investigations and Mutagenicity Studies," Research Report 412-1. DGMK, Hamburg, Germany.
8. Freeman, J. J., Federici, T. M., and McKee, R. H. (1993). Evaluation of the contribution of chronic skin irritation and selected compositional parameters to the tumorigenicity of petroleum middle distillates in mouse skin. Toxicology 81, 103-112.
9. Freeman, J. J., and McKee, R. H. (1993). The objectives and goals of dermal carcinogenicity testing of petroleum liquids. In Health Risk Assessment. Dermal and Inhalation Exposure and Absorption of Toxicants (R. G. M. Wang, J. B. Knaak, and H. I. Maibach, Eds.), pp. 283-289. CRC Press, Boca Raton, FL.
10. Freeman, J. J., McKee, R. H., Phillips, R. D., Plutnick, R. T., Scala, R. A., and Ackerman, L. J. (1990). A 90-day toxicity study of the effects of petroleum middle distillates on the skin of C3H mice. Toxicol. Ind. Health 6, 475-491.
11. Grasso, P., Sharratt, M., and Ingram, A. J. (1988). Early changes produced in mouse skin by the application of three middle distillates. Cancer Lett. 42, 147-155.
12. Ingram, A. J., and Grasso, P. (1991). Evidence for and possible mechanisms of nongenotoxic carcinogenesis in mouse skin. Mutat. Res. 248, 333-340.
13. Ingram, A. J., King, D. J., Grasso, P., and Sharratt, M. (1993). The early changes in mouse skin following topical application of a range of middle distillate oil products. J. Appl. Toxicol. 13, 247-257.
14. Jungen, H., Mellert, W., and Wenzel-Hartung, R. (1995). Studies on the tumor initiation/promotion potential of six middle distillates (MDs) in mouse skin. Fundam. Appl. Toxicol. 27, 114-120.
15. King, R. W. (1984). Skin carcinogenic potential of petroleum hydrocarbons: Separation and characterization of fractions for bioassay. In The Toxicology of Petroleum Hydrocarbons (H. N. MacFarland, C. E. Holdsworth, J. A. MacGregor, R. W. Call, and M. L. Kane, Eds.), pp. 170-184. American Petroleum Institute, Washington, DC.
16. Lewis, S. C., King, R. W., Cragg, S. T., and Hillman, D. W. (1984). Skin carcinogenic potential of petroleum hydrocarbons: Crude oil, distillate fractions and chemical class subfractions. In The Toxicology of Petroleum Hydrocarbons (H. N. MacFarland, C. E. Holdsworth, J. A. MacGregor, R. W. Call, and M. L. Kane, Eds.), pp. 185-195. American Petroleum Institute, Washington, DC.
17. McKee, R. H., Amoruso, M. A., Freeman, J. J., and Przygoda, R. T. (1994). Evaluation of the genetic toxicity of middle distillate fuels. Environ. Mol. Mutat. 23, 234-238.
18. McKee, R. H., Plutnick, R. T., and Przygoda, R. T. (1989). The carcinogenic initiating and promoting properties of a lightly refined paraffinic oil. Fundam. Appl. Toxicol. 12, 748-756.
19. Nessel, C. S., Freeman, J. J., Forgash, R. C., O'Connor, D. J., and McKee, R. H. (1996). A comparison of the tumor promoting activity of irritating and non-irritating doses of middle distillates in mouse skin. Toxicologist 30, 203.
20. 3H mouse cells produced by genotoxic but not nongenotoxic carcinogens. Fundam. Appl. Toxicol. 23, 261-267.
21. Roy, T. A., Johnson, S. W., Blackburn, G. R., and Mackerer, C. R. (1988). Correlation of mutagenic and dermal carcinogenic activities of mineral oils with polycyclic aromatic compound content. Fundam. Appl. Toxicol. 10, 466-476.
22. Skisak, C. M. (1991). The role of chronic acanthosis and subacute inflammation in tumour promotion in CD-1 mice by petroleum middle distillates. Toxicol. Appl. Pharmacol. 109, 399-411.
23. Thomas, D. G., Breslow, N., and Gart, J. J. (1977). Trend and homogeneity analysis of proportions and life table data. Comp. Biomed. Res. 10, 373-381.
24. Wilson, J. S., and Holland, L. M. (1982). The effect of application frequency on epidermal carcinogenesis bioassays. Toxicology 24, 45-53.
25. Witschi, H. P., Smith, L. H., Frome, E. L., Pequet-Goad, M. E., Griest, W. H., Ho, C. H., and Guerin, M. R. (1987). Skin tumorigenic potential of crude and refined coal liquids and analogous petroleum products. Fundam. Appl. Toxicol. 9, 297-303.