Adaptive evolution of Staphylococcus aureus during chronic endobronchial infection of a cystic fibrosis patient

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  McAdam, Paul R ^a   Holmes, Anne ^a,b   Templeton, Kate E ^b   Fitzgerald, J Ross ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SIGB; UNCLASSIFIED DRUG;

AIRWAY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIOPHAGE; BACTERIUM ISOLATE; BRONCHITIS; CONTROLLED STUDY; CYSTIC FIBROSIS; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC CORRELATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GROWTH RATE; HEMOLYSIS; MOLECULAR EVOLUTION; NONHUMAN; NUCLEOTIDE SEQUENCE; STAPHYLOCOCCUS AUREUS; ADAPTATION; BRONCHUS; CHRONIC DISEASE; GENETICS; GENOMICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; PATHOGENICITY; PHENOTYPE; PHYSIOLOGY;

STAPHYLOCOCCUS AUREUS;

ADAPTATION, PHYSIOLOGICAL; BRONCHI; CHRONIC DISEASE; CYSTIC FIBROSIS; EVOLUTION, MOLECULAR; GENETIC VARIATION; GENOMICS; HUMANS; PHENOTYPE; STAPHYLOCOCCUS AUREUS;

EID: 80052396609     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024301     Document Type: Article

References (32)

1. Kahl BC, (2010) Impact of Staphylococcus aureus on the pathogenesis of chronic cystic fibrosis lung disease. Int J Med Microbiol 300: 514-519.
2. Razvi S, Quittell L, Sewall A, Quinton H, Marshall B, et al. (2009) Respiratory microbiology of patients with cystic fibrosis in the United States, 1995 to 2005. Chest 136: 1554-1560.
3. Vu-Thien H, Hormigos K, Corbineau G, Fauroux B, Corvol H, et al. (2010) Longitudinal survey of Staphylococcus aureus in cystic fibrosis patients using a multiple-locus variable-number of tandem-repeats analysis method. BMC Microbiol 10: 24.
4. Gysin C, Alothman GA, Papsin BC, (2000) Sinonasal disease in cystic fibrosis: clinical characteristics, diagnosis, and management. Pediatr Pulmonol 30: 481-489.
5. Ridder-Schaphorn S, Ratjen F, Dubbers A, Haberle J, Falk S, et al. (2007) Nasal Staphylococcus aureus carriage is not a risk factor for lower-airway infection in young cystic fibrosis patients. J Clin Microbiol 45: 2979-2984.
6. Mainz JG, Naehrlich L, Schien M, Kading M, Schiller I, et al. (2009) Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis. Thorax 64: 535-540.
7. Branger C, Gardye C, Lambert-Zechovsky N, (1996) Persistence of Staphylococcus aureus strains among cystic fibrosis patients over extended periods of time. J Med Microbiol 45: 294-301.
8. Harrison F, (2007) Microbial ecology of the cystic fibrosis lung. Microbiology 153: 917-923.
9. Goerke C, Wolz C, (2010) Adaptation of Staphylococcus aureus to the cystic fibrosis lung. International journal of medical microbiology: IJMM 300: 520-525.
10. Tuchscherr L, Medina E, Hussain M, Völker W, Heitmann V, et al. (2011) Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection. EMBO Mol Med 3: 129-41.
11. Besier S, Smaczny C, von Mallinckrodt C, Krahl A, Ackermann H, et al. (2007) Prevalence and Clinical Significance of Staphylococcus aureus Small-Colony Variants in Cystic Fibrosis Lung Disease. J Clin Microbiol 45: 168-172.
12. Besier S, Zander J, Kahl BC, Kraiczy P, Brade V, et al. (2008) The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. Antimicrob Agents Chemother 52: 2183-2189.
13. Oliver A, (2010) Mutators in cystic fibrosis chronic lung infection: Prevalence, mechanisms, and consequences for antimicrobial therapy. Int J Med Microbiol 300: 563-572.
14. Prunier AL, Malbruny B, Laurans M, Brouard J, Duhamel JF, et al. (2003) High Rate of Macrolide Resistance in Staphylococcus aureus Strains from Patients with Cystic Fibrosis Reveals High Proportions of Hypermutable Strains. J Infect Dis 187: 1709-1716.
15. Prunier A-L, Leclercq R, (2005) Role of mutS and mutL genes in hypermutability and recombination in Staphylococcus aureus. J Bacteriol 187: 3455-3464.
16. Hogardt M, Heesemann J, (2010) Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung. Int J Med Microbiol 300: 557-562.
17. Smith EE, Buckley DG, Wu Z, Saenphimmachak C, Hoffman LR, et al. (2006) Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc Natl Acad Sci (USA) 103: 8487-8492.
18. Mwangi MM, Wu SW, Zhou Y, Sieradzki K, de Lencastre H, et al. (2007) Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing. Proc Natl Acad Sci (USA) 104: 9451-9456.
19. Gao W, Chua K, Davies JK, Newton HJ, Seemann T, et al. (2010) Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection. PLoS Pathogens 6: e1000944.
20. Pohl K, Francois P, Stenz L, Schlink F, Geiger T, et al. (2009) CodY in Staphylococcus aureus: a regulatory link between metabolism and virulence gene expression. J Bacteriol 191: 2953-2963.
21. Rocha EP, Smith JM, Hurst LD, Holden MT, Cooper JE, et al. (2006) Comparisons of dN/dS are time dependent for closely related bacterial genomes. J Theor Biol 239: 226-235.
22. Nagaev I, Björkman J, Andersson DI, Hughes D, (2001) Biological cost and compensatory evolution in fusidic acid-resistant Staphylococcus aureus. Mol Microbiol 40: 433-439.
23. Majerczyk CD, Dunman PM, Luong TT, Lee CY, Sadykov MR, et al. (2010) Direct targets of CodY in Staphylococcus aureus. J Bacteriol 192: 2861-2877.
24. Levdikov VM, Blagova E, Joseph P, Sonenshein AL, Wilkinson AJ, (2006) The structure of CodY, a GTP- and isoleucine-responsive regulator of stationary phase and virulence in gram-positive bacteria. J Biol Chem 281: 11366-11373.
25. Meier S, Goerke C, Wolz C, Seidl K, Homerova D, et al. (2007) sigmaB and the sigmaB-dependent arlRS and yabJ-spoVG loci affect capsule formation in Staphylococcus aureus. Infect Immun 75: 4562-4571.
26. Moisan H, Brouillette E, Jacob CL, Langlois-Bégin P, Michaud S, et al. (2006) Transcription of virulence factors in Staphylococcus aureus small-colony variants isolated from cystic fibrosis patients is influenced by SigB. J Bacteriol 188: 64-76.
27. Mitchell G, Séguin DL, Asselin A-E, Déziel E, Cantin AM, et al. (2010) Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2-heptylquinoline-N-oxide. BMC Microbiol 10: 33.
28. Karlsson-Kanth A, Tegmark-Wisell K, Arvidson S, Oscarsson J, (2006) Natural human isolates of Staphylococcus aureus selected for high production of proteases and alpha-hemolysin are sigmaB deficient. Int J Med Microbiol 296: 229-236.
29. Entenza JM, Moreillon P, Senn MM, Kormanec J, Dunman PM, et al. (2005) Role of sigmaB in the expression of Staphylococcus aureus cell wall adhesins ClfA and FnbA and contribution to infectivity in a rat model of experimental endocarditis. Infect Immun 73: 990-998.
30. Goerke C, Matias y Papenberg S, Dasbach S, Dietz K, Ziebach R, et al. (2004) Increased frequency of genomic alterations in Staphylococcus aureus during chronic infection is in part due to phage mobilization. J Infect Dise 189: 724-734.
31. Holden MTG, Feil EJ, Lindsay JA, Peacock SJ, Day NPJ, et al. (2004) Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci (USA) 101: 9786-9791.
32. Robinson DA, Kearns AM, Holmes A, Morrison D, Grundmann H, et al. (2005) Re-emergence of early pandemic Staphylococcus aureus as a community-acquired meticillin-resistant clone. Lancet 365: 1256-1258.