Detection of C677T mutation of MTHFR in subject with coronary heart disease by hairpin probe with enzymatic color on microarray

Biosensors and Bioelectronics

Volumn 28, Issue 1, 2011, Pages 84-90

  Chen, Qinghai ^a   Sun, Yue ^b   Zhang, Linqun ^a   Deng, Kun ^a   xia, Han ^a   Xing, Hua ^a   Xiang, Yang ^a   Ran, Boli ^a   Zhang, Mohan ^b   Xu, Xiaodong ^b   Fu, Weiling ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Baio Technology Limited Company   (China)

Author keywords

Coronary heart disease (CHD); Emplification effect of enzymatic color; Hairpin DNA probe; Molecular beacon (MB); MTHFR gene C677T mutation; Single base mismatch

Indexed keywords

CORONARY HEART DISEASE; EMPLIFICATION EFFECT OF ENZYMATIC COLOR; HAIRPIN DNA PROBE; MOLECULAR BEACON (MB); MTHFR GENE C677T MUTATION; SINGLE-BASE MISMATCH;

CARDIOLOGY; COLOR; DISEASE CONTROL; FLUORESCENCE; GENES; MOLECULES; PROBES; QUENCHING; SIGNAL DETECTION;

HEART;

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); GENOMIC DNA;

ADULT; ARTICLE; CONTROLLED STUDY; CORONARY RISK; DNA HYBRIDIZATION; DNA PROBE; FEMALE; FLUORESCENCE; GENE; GENE AMPLIFICATION; GENE FREQUENCY; GENE MUTATION; HAIRPIN PROBE WITH ENZYMATIC COLOR ON MICROARRAY; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MOLECULAR BEACON; MTHFR GENE; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; TEMPERATURE SENSITIVITY;

ADULT; AGED; BIOSENSING TECHNIQUES; COLOR; CORONARY DISEASE; DNA PROBES; FEMALE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; MALE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; TEMPERATURE;

EID: 80052364551     PISSN: 09565663     EISSN: 18734235     Source Type: Journal    
DOI: 10.1016/j.bios.2011.07.002     Document Type: Article

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