-
1
-
-
0029051439
-
Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
-
PMID: 7539918; DOI: 10.1073/pnas.92.12.5510
-
Wang G.L., Jiang B.H., Rue E.A., Semenza GL. Hypoxiainducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 1995; 92:5510-4; PMID: 7539918; DOI: 10.1073/pnas.92.12.5510.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5510-5514
-
-
Wang, G.L.1
Jiang, B.H.2
Rue, E.A.3
Semenza, G.L.4
-
2
-
-
31044447666
-
Targeting the molecular basis for tumour hypoxia
-
PMID: 15831177; DOI: 10.1017/ S1462399405009117
-
Carroll V.A., Ashcroft M. Targeting the molecular basis for tumour hypoxia. Expert Rev Mol Med 2005; 7:1-16; PMID: 15831177; DOI: 10.1017/ S1462399405009117.
-
(2005)
Expert Rev Mol Med
, vol.7
, pp. 1-16
-
-
Carroll, V.A.1
Ashcroft, M.2
-
3
-
-
1642387020
-
Hypoxia-inducible factor (HIF-1)alpha: Its protein stability and biological functions
-
PMID: 15031665
-
Lee J.W., Bae S.H., Jeong J.W., Kim S.H., Kim K.W. Hypoxia-inducible factor (HIF-1)alpha: Its protein stability and biological functions. Exp Mol Med 2004; 36:1-12; PMID: 15031665.
-
(2004)
Exp Mol Med
, vol.36
, pp. 1-12
-
-
Lee, J.W.1
Bae, S.H.2
Jeong, J.W.3
Kim, S.H.4
Kim, K.W.5
-
4
-
-
0033571682
-
Overexpression of hypoxiainducible factor-1α in common human cancers and their metastases
-
PMID: 10582706
-
Zhong H., De Marzo A.M., Laughner E., Lim M., Hilton D.A., Zagzag D., et al. Overexpression of hypoxiainducible factor-1α in common human cancers and their metastases. Cancer Res 1999; 59:5830-5835; PMID: 10582706.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
Lim, M.4
Hilton, D.A.5
Zagzag, D.6
-
5
-
-
0034333026
-
Pancreatic tumors show high levels of hypoxia
-
PMID: 11072146; DOI: 10.1016/S0360- 3016(00)00803-8
-
Koong A.C., Mehta V.K., Le Q.T., Fisher G.A., Terris D.J., Brown J.M., et al. Pancreatic tumors show high levels of hypoxia. Int J Radiat Oncol Biol Phys 2000; 48:919-22; PMID: 11072146; DOI: 10.1016/S0360- 3016(00)00803-8.
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.48
, pp. 919-922
-
-
Koong, A.C.1
Mehta, V.K.2
Le, Q.T.3
Fisher, G.A.4
Terris, D.J.5
Brown, J.M.6
-
6
-
-
0034654174
-
Modulation of hypoxiainducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol-3-kinase/PTEN/ AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
PMID: 10749120
-
Zhong H., Chiles K., Feldser D., Laughner E., Hanrahan C., Georgescu M.M., et al. Modulation of hypoxiainducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol-3-kinase/PTEN/ AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics. Cancer Res 2000; 60:1541-1545; PMID: 10749120.
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
Laughner, E.4
Hanrahan, C.5
Georgescu, M.M.6
-
7
-
-
45849149957
-
High expression of HIF1α is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF and bFGF
-
PMID: 18592007
-
Hoffmann A.C., Mori R., Vallbohmer D., Brabender J., Klein E., Drebber U., et al. High expression of HIF1α is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF and bFGF. Neoplasia 2008; 10:674-679; PMID: 18592007.
-
(2008)
Neoplasia
, vol.10
, pp. 674-679
-
-
Hoffmann, A.C.1
Mori, R.2
Vallbohmer, D.3
Brabender, J.4
Klein, E.5
Drebber, U.6
-
8
-
-
0347478156
-
Clinicopathological significance of hypoxiainducible factor-1α expression in human pancreatic carcinoma
-
PMID: 14636255; DOI: 10.1111/j.1365-2559.2003.01733.x
-
Kitada T., Seki S., Sakaguchi H., Sawada T., Hirakawa K., Wakasa K. Clinicopathological significance of hypoxiainducible factor-1α expression in human pancreatic carcinoma. Histopathology 2003; 43:550-5; PMID: 14636255; DOI: 10.1111/j.1365-2559.2003.01733.x.
-
(2003)
Histopathology
, vol.43
, pp. 550-555
-
-
Kitada, T.1
Seki, S.2
Sakaguchi, H.3
Sawada, T.4
Hirakawa, K.5
Wakasa, K.6
-
9
-
-
0842333201
-
Prognostic significance of HIF-1α overexpression in human pancreatic cancer
-
PMID: 14981919
-
Shibaji T, Nagao M, Ikeda N, Kanehiro H, Hisanaga M, Ko S, et al. Prognostic significance of HIF-1α overexpression in human pancreatic cancer. Anticancer Res 2003; 23:4721-4727; PMID: 14981919.
-
(2003)
Anticancer Res
, vol.23
, pp. 4721-4727
-
-
Shibaji, T.1
Nagao, M.2
Ikeda, N.3
Kanehiro, H.4
Hisanaga, M.5
Ko, S.6
-
10
-
-
20644470124
-
Expression of hypoxia-inducible factors is correlated with the presence of a fibrotic focus and angiogenesis in pancreatic ductal adenocarcinomas
-
PMID:15910598; DOI: 10.1111/j.1365-2559.2005.02160.x
-
Couvelard A., O'Toole D., Leek R., Turley H., Sauvanet A., Degott C., et al. Expression of hypoxia-inducible factors is correlated with the presence of a fibrotic focus and angiogenesis in pancreatic ductal adenocarcinomas. Histopathology 2005; 46:668-76; PMID:15910598; DOI: 10.1111/j.1365-2559.2005. 02160.x.
-
(2005)
Histopathology
, vol.46
, pp. 668-676
-
-
Couvelard, A.1
O'Toole, D.2
Leek, R.3
Turley, H.4
Sauvanet, A.5
Degott, C.6
-
11
-
-
34447266708
-
Expression of hypoxia-inducible factor-1α and associated proteins in pancreatic ductal adenocarcinoma and their impact on prognosis
-
PMID: 17487356
-
Sun H.C., Qiu Z.J., Liu J., Sun J., Jiang T., Huang K.J., et al. Expression of hypoxia-inducible factor-1α and associated proteins in pancreatic ductal adenocarcinoma and their impact on prognosis. Int J Oncol 2007; 30:1359-1367; PMID: 17487356.
-
(2007)
Int J Oncol
, vol.30
, pp. 1359-1367
-
-
Sun, H.C.1
Qiu, Z.J.2
Liu, J.3
Sun, J.4
Jiang, T.5
Huang, K.J.6
-
12
-
-
77957309341
-
Pancreatic cancer cells expressing hypoxia-inducible factor-1α tend to be adjacent to intratumoral blood vessels
-
PMID: 20924188; DOI: 10.1159/000319876
-
Cheng B.Q., Segersvärd R., Permert J., Wang F. Pancreatic cancer cells expressing hypoxia-inducible factor-1α tend to be adjacent to intratumoral blood vessels. Eur Surg Res 2010; 45:134-7; PMID: 20924188; DOI: 10.1159/000319876.
-
(2010)
Eur Surg Res
, vol.45
, pp. 134-137
-
-
Cheng, B.Q.1
Segersvärd, R.2
Permert, J.3
Wang, F.4
-
13
-
-
0242559086
-
Hypoxia-inducible factor- 1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance
-
PMID: 12919954; DOI: 10.1093/carcin/bgg132
-
Tanimoto K., Yoshiga K., Eguchi H., Kaneyasu M., Ukon K., Kumazaki T., et al. Hypoxia-inducible factor- 1alpha polymorphisms associated with enhanced transactivation capacity, implying clinical significance. Carcinogenesis 2003; 24:1779-83; PMID: 12919954; DOI: 10.1093/carcin/bgg132.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1779-1783
-
-
Tanimoto, K.1
Yoshiga, K.2
Eguchi, H.3
Kaneyasu, M.4
Ukon, K.5
Kumazaki, T.6
-
14
-
-
0030787469
-
Transactivation and inhibitory domains of hypoxiainducible factor 1alpha. Modulation of transcriptional activity by oxygen tension
-
PMID: 9235919; DOI: 10.1074/ jbc.272.31.19253
-
Jiang B.H., Zheng J.Z., Leung S.W., Roe R., Semenza GL. Transactivation and inhibitory domains of hypoxiainducible factor 1alpha. Modulation of transcriptional activity by oxygen tension. J Biol Chem 1997; 272:19253-60; PMID: 9235919; DOI: 10.1074/ jbc.272.31.19253.
-
(1997)
J Biol Chem
, vol.272
, pp. 19253-19260
-
-
Jiang, B.H.1
Zheng, J.Z.2
Leung, S.W.3
Roe, R.4
Semenza, G.L.5
-
15
-
-
17644397056
-
Identification of hypoxia-inducible factor-1alpha (HIF-1alpha) polymorphism as a mutation in prostate cancer that prevents normoxia-induced degradation
-
PMID: 15538748; DOI: 10.1002/ pros.20190
-
Fu X.S., Choi E., Bubley G.J., Balk SP. Identification of hypoxia-inducible factor-1alpha (HIF-1alpha) polymorphism as a mutation in prostate cancer that prevents normoxia-induced degradation. Prostate 2005; 63:215-21; PMID: 15538748; DOI: 10.1002/ pros.20190.
-
(2005)
Prostate
, vol.63
, pp. 215-221
-
-
Fu, X.S.1
Choi, E.2
Bubley, G.J.3
Balk, S.P.4
-
16
-
-
70449569293
-
The association between hypoxia inducible factor-1alpha gene polymorphisms and increased susceptibility to oral cancer
-
PMID: 19717330; DOI: 10.1016/j.oraloncology. 2009.07.015
-
Chen M.K., Chiou H.L., Su S.C., Chung T.T., Tseng H.C., Tsai H.T., et al. The association between hypoxia inducible factor-1alpha gene polymorphisms and increased susceptibility to oral cancer. Oral Oncol 2009; 45:222- 6; PMID: 19717330; DOI: 10.1016/j.oraloncology. 2009.07.015.
-
(2009)
Oral Oncol
, vol.45
, pp. 222-226
-
-
Chen, M.K.1
Chiou, H.L.2
Su, S.C.3
Chung, T.T.4
Tseng, H.C.5
Tsai, H.T.6
-
17
-
-
77955116731
-
Hypoxia inducible factor-1alpha gene polymorphism G1790A and its interaction with tobacco and alcohol consumptions increase susceptibility to hepatocellular carcinoma
-
PMID: 20648588; DOI: 10.1002/jso.21539
-
Hsiao P.C., Chen M.K., Su S.C., Ueng K.C., Chen Y.C., Hsieh Y.H., et al. Hypoxia inducible factor-1alpha gene polymorphism G1790A and its interaction with tobacco and alcohol consumptions increase susceptibility to hepatocellular carcinoma. J Surg Oncol 2010; 102:163- 9; PMID: 20648588; DOI: 10.1002/jso.21539.
-
(2010)
J Surg Oncol
, vol.102
, pp. 163-169
-
-
Hsiao, P.C.1
Chen, M.K.2
Su, S.C.3
Ueng, K.C.4
Chen, Y.C.5
Hsieh, Y.H.6
-
18
-
-
69849088105
-
Associations between hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms and risk of developing breast cancer
-
PMID: 19580347; DOI: 10.4149/neo-2009-05-441
-
Naidu R., Har Y.C., Taib NA. Associations between hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms and risk of developing breast cancer. Neoplasma 2009; 56:441-7; PMID: 19580347; DOI: 10.4149/neo-2009-05-441.
-
(2009)
Neoplasma
, vol.56
, pp. 441-447
-
-
Naidu, R.1
Har, Y.C.2
Taib, N.A.3
-
19
-
-
77956198446
-
Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk
-
PMID: 20572162
-
Knechtel G., Szkandera J., Stotz M., Hofmann G., Langsenlehner U., Krippl P., et al. Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk. Mol Carcinog 2010; 49:805-809; PMID: 20572162.
-
(2010)
Mol Carcinog
, vol.49
, pp. 805-809
-
-
Knechtel, G.1
Szkandera, J.2
Stotz, M.3
Hofmann, G.4
Langsenlehner, U.5
Krippl, P.6
-
20
-
-
33750489434
-
Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients
-
PMID: 16865676; DOI: 10.1002/mc.20209
-
Fransén K., Fenech M., Fredrikson M., Dabrosin C., Söderkvist P. Association between ulcerative growth and hypoxia inducible factor-1alpha polymorphisms in colorectal cancer patients. Mol Carcinog 2006; 45:833- 40; PMID: 16865676; DOI: 10.1002/mc.20209.
-
(2006)
Mol Carcinog
, vol.45
, pp. 833-840
-
-
Fransén, K.1
Fenech, M.2
Fredrikson, M.3
Dabrosin, C.4
Söderkvist, P.5
-
21
-
-
77952973346
-
Predictive and prognostic value of CA 19-9 in resected pancreatic adenocarcinoma
-
PMID: 19756875; DOI: 10.1007/s11605-009-0849-z
-
Barton J.G., Bois J.P., Sarr M.G., Wood C.M., Qin R., Thomsen K.M., et al. Predictive and prognostic value of CA 19-9 in resected pancreatic adenocarcinoma. J Gastrointest Surg 2009; 13:2050-8; PMID: 19756875; DOI: 10.1007/s11605-009-0849-z.
-
(2009)
J Gastrointest Surg
, vol.13
, pp. 2050-2058
-
-
Barton, J.G.1
Bois, J.P.2
Sarr, M.G.3
Wood, C.M.4
Qin, R.5
Thomsen, K.M.6
-
22
-
-
67651005032
-
Polymorphisms in the hypoxia inducible factor-1alpha and the impact on the prognosis of early stages of oral cancer
-
PMID: 19449077; DOI: 10.1245/s10434-009-0503-8
-
Muñoz-Guerra M.F., Fernández-Contreras M.E., Moreno A.L., Martín I.D., Herráez B., Gamallo C. Polymorphisms in the hypoxia inducible factor-1alpha and the impact on the prognosis of early stages of oral cancer. Ann Surg Oncol 2009; 16:2351-8; PMID: 19449077; DOI: 10.1245/s10434-009-0503-8.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 2351-2358
-
-
Muñoz-Guerra, M.F.1
Fernández-Contreras, M.E.2
Moreno, A.L.3
Martín, I.D.4
Herráez, B.5
Gamallo, C.6
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