-
1
-
-
33845739839
-
Domain interdependence in the biosynthetic assembly of CFTR
-
Cui, L., Aleksandrov, L., Chang, X. B., Hou, Y. X., He, L., Hegedus, T., et al. (2007) Domain interdependence in the biosynthetic assembly of CFTR. J. Mol. Biol. 365, 981–994.
-
(2007)
J. Mol. Biol.
, vol.365
, pp. 981-994
-
-
Cui, L.1
Aleksandrov, L.2
Chang, X.B.3
Hou, Y.X.4
He, L.5
Hegedus, T.6
-
2
-
-
11444266284
-
The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR
-
Du, K., Sharma, M., and Lukacs, G. L. (2005) The DeltaF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR. Nat. Struct. Mol. Biol. 12, 17–25.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 17-25
-
-
Du, K.1
Sharma, M.2
Lukacs, G.L.3
-
3
-
-
42149120706
-
Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function
-
Serohijos, A. W., Hegedus, T., Aleksandrov, A. A., He, L., Cui, L., Dokholyan, N. V., et al. (2008) Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function. Proc. Natl. Acad. Sci. USA 105, 3256–3261.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3256-3261
-
-
Serohijos, A.W.1
Hegedus, T.2
Aleksandrov, A.A.3
He, L.4
Cui, L.5
Dokholyan, N.V.6
-
4
-
-
0033559258
-
The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis
-
Meacham, G. C., Lu, Z., King, S., Sorscher, E., Tousson, A., and Cyr, D. M. (1999) The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis. EMBO J. 18, 1492–1505.
-
(1999)
EMBO J
, vol.18
, pp. 1492-1505
-
-
Meacham, G.C.1
Lu, Z.2
King, S.3
Sorscher, E.4
Tousson, A.5
Cyr, D.M.6
-
5
-
-
0028006681
-
Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins
-
Ward, C. L., and Kopito, R. R. (1994) Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins. J. Biol. Chem. 269, 25710–25718.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25710-25718
-
-
Ward, C.L.1
Kopito, R.R.2
-
6
-
-
58149279835
-
Assembly and mis-assembly of CFTR: Folding defects caused by deletion of F508 occur before and after the calnexin-dependent association of MSD1 and MSD2. Mol. Biol
-
Rosser, M. F., Grove, D. E., Chen, L., and Cyr, D. M. (2008) Assembly and mis-assembly of CFTR: Folding defects caused by deletion of F508 occur before and after the calnexin-dependent association of MSD1 and MSD2. Mol. Biol. Cell 19, 4570–4579.
-
(2008)
Cell
, vol.19
, pp. 4570-4579
-
-
Rosser, M.F.1
Grove, D.E.2
Chen, L.3
Cyr, D.M.4
-
7
-
-
0032401771
-
Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome
-
Loo, M. A., Jensen, T. J., Cui, L., Hou, Y., Chang, X. B., and Riordan, J. R. (1998) Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome. EMBO J. 17, 6879–6887.
-
(1998)
EMBO J
, vol.17
, pp. 6879-6887
-
-
Loo, M.A.1
Jensen, T.J.2
Cui, L.3
Hou, Y.4
Chang, X.B.5
Riordan, J.R.6
-
8
-
-
33750842131
-
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
-
Wang, X., Venable, J., LaPointe, P., Hutt, D. M., Koulov, A. V., Coppinger, J., et al. (2006) Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Cell 127, 803–815.
-
(2006)
Cell
, vol.127
, pp. 803-815
-
-
Wang, X.1
Venable, J.2
Lapointe, P.3
Hutt, D.M.4
Koulov, A.V.5
Coppinger, J.6
-
9
-
-
0035142877
-
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
-
Meacham, G. C., Patterson, C., Zhang, W., Younger, J. M., and Cyr, D. M. (2001) The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation. Nat. Cell. Biol. 3, 100–105.
-
(2001)
Nat. Cell. Biol.
, vol.3
, pp. 100-105
-
-
Meacham, G.C.1
Patterson, C.2
Zhang, W.3
Younger, J.M.4
Cyr, D.M.5
-
10
-
-
33746675669
-
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator
-
Younger, J. M., Chen, L., Ren, H. Y., Rosser, M. F., Turnbull, E. L., Fan, C. Y., et al. (2006) Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator. Cell 126, 571–582.
-
(2006)
Cell
, vol.126
, pp. 571-582
-
-
Younger, J.M.1
Chen, L.2
Ren, H.Y.3
Rosser, M.F.4
Turnbull, E.L.5
Fan, C.Y.6
-
11
-
-
0742323006
-
Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway
-
Dalal, S., Rosser, M. F., Cyr, D. M., and Hanson, P. I. (2004) Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway. Mol. Biol. Cell 15, 637–648.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 637-648
-
-
Dalal, S.1
Rosser, M.F.2
Cyr, D.M.3
Hanson, P.I.4
-
12
-
-
44949249968
-
Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTR{Delta}F508
-
Morito, D., Hirao, K., Oda, Y., Hosokawa, N., Tokunaga, F., Cyr, D. M., et al. (2008) Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTR{Delta}F508. Mol. Biol. Cell 19, 1328– 1336.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 1328-1336
-
-
Morito, D.1
Hirao, K.2
Oda, Y.3
Hosokawa, N.4
Tokunaga, F.5
Cyr, D.M.6
-
13
-
-
44649096231
-
BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex
-
Wang, B., Heath-Engel, H., Zhang, D., Nguyen, N., Thomas, D. Y., Hanrahan, J. W., et al. (2008) BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex. Cell 133, 1080–1092.
-
(2008)
Cell
, vol.133
, pp. 1080-1092
-
-
Wang, B.1
Heath-Engel, H.2
Zhang, D.3
Nguyen, N.4
Thomas, D.Y.5
Hanrahan, J.W.6
|