-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin 2009; 59: 225-249.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
2
-
-
4744337716
-
Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer
-
Petrylak DP, Tangen CM, Hussain MH, Lara PN Jr, Jones JA, Taplin ME, et al. Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. N Engl J Med 2004; 351: 1513-1520.
-
(2004)
N Engl J Med
, vol.351
, pp. 1513-1520
-
-
Petrylak, D.P.1
Tangen, C.M.2
Hussain, M.H.3
Lara Jr., P.N.4
Jones, J.A.5
Taplin, M.E.6
-
3
-
-
4744366279
-
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
-
Tannock IF, de Wit R, Berry WR, Horti J, Pluzanska A, Chi KN, et al. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 2004; 351: 1502-1512.
-
(2004)
N Engl J Med
, vol.351
, pp. 1502-1512
-
-
Tannock, I.F.1
de Wit, R.2
Berry, W.R.3
Horti, J.4
Pluzanska, A.5
Chi, K.N.6
-
4
-
-
33644675811
-
Biology of progressive, castration-resistant prostate cancer: Directed therapies targeting the androgen-receptor signaling axis
-
Scher HI, Sawyers CL. Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis. J Clin Oncol 2005; 23: 8253-8261.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8253-8261
-
-
Scher, H.I.1
Sawyers, C.L.2
-
5
-
-
66149161780
-
Castration-resistant prostate cancer: Locking up the molecular escape routes
-
Attar RM, Takimoto CH, Gottardis MM. Castration-resistant prostate cancer: locking up the molecular escape routes. Clin Cancer Res 2009; 15: 3251-3255.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3251-3255
-
-
Attar, R.M.1
Takimoto, C.H.2
Gottardis, M.M.3
-
6
-
-
65649090203
-
Development of a second-generation antiandrogen for treatment of advanced prostate cancer
-
Tran C, Ouk S, Clegg NJ, Chen Y, Watson PA, Arora V, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science. 2009;324: 787-790.
-
(2009)
Science
, vol.324
, pp. 787-790
-
-
Tran, C.1
Ouk, S.2
Clegg, N.J.3
Chen, Y.4
Watson, P.A.5
Arora, V.6
-
7
-
-
77952105685
-
Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study
-
Scher HI, Beer TM, Higano CS, Anand A, Taplin ME, Efstathiou E, et al. Antitumour activity of MDV3100 in castration-resistant prostate cancer: A phase 1-2 study. Lancet 2010; 375: 1437-1446.
-
(2010)
Lancet
, vol.375
, pp. 1437-1446
-
-
Scher, H.I.1
Beer, T.M.2
Higano, C.S.3
Anand, A.4
Taplin, M.E.5
Efstathiou, E.6
-
8
-
-
84857107038
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00974311, Acssesed on: Jul 10, 2010
-
US Institute of Health, Clinical Trials. gov identifier NCT00974311. Available at http://clinicaltrials.gov (Acssesed on: Jul 10, 2010).
-
-
-
-
9
-
-
1842457650
-
Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: A phase III trial (CALGB 9583)
-
Small EJ, Halabi S, Dawson NA, Stadler WM, Rini BI, Picus J, et al. Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: A phase III trial (CALGB 9583). J Clin Oncol 2004;22: 1025-1033.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1025-1033
-
-
Small, E.J.1
Halabi, S.2
Dawson, N.A.3
Stadler, W.M.4
Rini, B.I.5
Picus, J.6
-
10
-
-
77951523950
-
Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castrationresistant prostate cancer who received prior ketoconazole therapy
-
Ryan CJ, Smith MR, Fong L, Rosenberg JE, Kantoff P, Raynaud F, et al. Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castrationresistant prostate cancer who received prior ketoconazole therapy. J Clin Oncol 2010; 28: 1481-1488.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1481-1488
-
-
Ryan, C.J.1
Smith, M.R.2
Fong, L.3
Rosenberg, J.E.4
Kantoff, P.5
Raynaud, F.6
-
11
-
-
68949094223
-
Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer
-
Attard G, Reid AH, A'Hern R Parker C, Oommen NB, Folkerd E, Messiou C, et al. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer. J Clin Oncol 2009; 27: 3742-3748.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3742-3748
-
-
Attard, G.1
Reid, A.H.2
A'Hern, R.3
Parker, C.4
Oommen, N.B.5
Folkerd, E.6
Messiou, C.7
-
12
-
-
84857105278
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00638690, Acssesed on: January 8, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00638690. Available at http://clinicaltrials.gov (Acssesed on: January 8, 2011).
-
-
-
-
13
-
-
84857107036
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00887198, Acssesed on: Jan 8, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00887198. Available at http://clinicaltrials.gov (Acssesed on: Jan 8, 2011).
-
-
-
-
15
-
-
77956235472
-
Overcoming persistent dependency on androgen signaling after progression to castrationresistant prostate cancer
-
Yamaoka M, Hara T, Kusaka M. Overcoming persistent dependency on androgen signaling after progression to castrationresistant prostate cancer. Clin Cancer Res 2010; 16: 4319-4324.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4319-4324
-
-
Yamaoka, M.1
Hara, T.2
Kusaka, M.3
-
16
-
-
80052338353
-
-
American Society of Clinical Oncology Genitourinary Cancers Symposium. San Francisco, USA
-
Dreicer R, Agus DB, MacVicar GR, MacLean D, Zhang T, Stadler WM, et al. Safety, pharmacokinetics, and efficacy of TAK-700 in castration-resistant, metastatic prostate cancer: a phase I/II, openlabel study. American Society of Clinical Oncology Genitourinary Cancers Symposium. San Francisco, USA (2010).
-
(2010)
Safety, Pharmacokinetics, and Efficacy of TAK-700 In Castration-resistant, Metastatic Prostate Cancer: A Phase I/II, Openlabel Study
-
-
Dreicer, R.1
Agus, D.B.2
Macvicar, G.R.3
Maclean, D.4
Zhang, T.5
Stadler, W.M.6
-
17
-
-
84857107037
-
-
Millennium press release, Accessed on: January 10, 2011
-
Millennium press release. Available at: http://investor.millennium.com/ (Accessed on: January 10, 2011).
-
-
-
-
18
-
-
53349101498
-
Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer
-
Vasaitis T, Belosay A, Schayowitz A, Khandelwal A, Chopra P, Gediya LK, et al. Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer. Mol Cancer Ther 2008; 7: 2348-2357.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2348-2357
-
-
Vasaitis, T.1
Belosay, A.2
Schayowitz, A.3
Khandelwal, A.4
Chopra, P.5
Gediya, L.K.6
-
19
-
-
38349186341
-
Synergistic effect of a novel antiandrogen, VN/124-1, and signal transduction inhibitors in prostate cancer progression to hormone independence in vitro
-
Schayowitz A, Sabnis G, Njar VC, Brodie AM. Synergistic effect of a novel antiandrogen, VN/124-1, and signal transduction inhibitors in prostate cancer progression to hormone independence in vitro. Mol Cancer Ther 2008; 7: 121-132.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 121-132
-
-
Schayowitz, A.1
Sabnis, G.2
Njar, V.C.3
Brodie, A.M.4
-
20
-
-
77957238643
-
Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR
-
Schayowitz A, Sabnis G, Goloubeva O, Njar VC, Brodie AM. Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR. Br J Cancer 2010; 103: 1001-1007.
-
(2010)
Br J Cancer
, vol.103
, pp. 1001-1007
-
-
Schayowitz, A.1
Sabnis, G.2
Goloubeva, O.3
Njar, V.C.4
Brodie, A.M.5
-
21
-
-
84857101765
-
-
Tokai Pharmaceuticals press release, Accessed on: January 10, 2011
-
Tokai Pharmaceuticals press release. Available at: http://www.tokaipharma.com/ (Accessed on: January 10, 2011).
-
-
-
-
22
-
-
33750728404
-
Targeting bone metastasis in prostate cancer with endothelin receptor antagonists
-
Carducci MA, Jimeno A. Targeting bone metastasis in prostate cancer with endothelin receptor antagonists. Clin Cancer Res 2006; 12: 6296s-300s.
-
(2006)
Clin Cancer Res
, vol.12
-
-
Carducci, M.A.1
Jimeno, A.2
-
23
-
-
35648968713
-
A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormonerefractory prostate cancer
-
Carducci MA, Saad F, Abrahamsson PA, Dearnaley DP, Schulman CC, North SA, et al. A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormonerefractory prostate cancer. Cancer 2007; 110: 1959-1966.
-
(2007)
Cancer
, vol.110
, pp. 1959-1966
-
-
Carducci, M.A.1
Saad, F.2
Abrahamsson, P.A.3
Dearnaley, D.P.4
Schulman, C.C.5
North, S.A.6
-
24
-
-
55549112219
-
Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer
-
Nelson JB, Love W, Chin JL, Saad F, Schulman CC, Sleep DJ, et al. Phase 3, randomized, controlled trial of atrasentan in patients with nonmetastatic, hormone-refractory prostate cancer. Cancer 2008; 113: 2478-2487.
-
(2008)
Cancer
, vol.113
, pp. 2478-2487
-
-
Nelson, J.B.1
Love, W.2
Chin, J.L.3
Saad, F.4
Schulman, C.C.5
Sleep, D.J.6
-
25
-
-
33749045722
-
Endothelin receptor A blockade enhances taxane effects in prostate cancer in vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer
-
Akhavan A, McHugh KH, Guruli G, Bies RR, Zamboni WC, Strychor SA, et al. Endothelin receptor A blockade enhances taxane effects in prostate cancer in vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer. Neoplasia. 2006; 8: 725-732.
-
(2006)
Neoplasia
, vol.8
, pp. 725-732
-
-
Akhavan, A.1
McHugh, K.H.2
Guruli, G.3
Bies, R.R.4
Zamboni, W.C.5
Strychor, S.A.6
-
26
-
-
34248584876
-
In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer
-
Banerjee S, Hussain M, Wang Z, Saliganan A, Che M, Bonfil D, et al. In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer. Cancer Res 2007; 67: 3818-3826.
-
(2007)
Cancer Res
, vol.67
, pp. 3818-3826
-
-
Banerjee, S.1
Hussain, M.2
Wang, Z.3
Saliganan, A.4
Che, M.5
Bonfil, D.6
-
27
-
-
58149143013
-
A phase I-II study of docetaxel and atrasentan in men with castration-resistant metastatic prostate cancer
-
Armstrong AJ, Creel P, Turnbull J, Moore C, Jaffe TA, Haley S, et al. A phase I-II study of docetaxel and atrasentan in men with castration-resistant metastatic prostate cancer. Clin Cancer Res 2008; 14: 6270-6276.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6270-6276
-
-
Armstrong, A.J.1
Creel, P.2
Turnbull, J.3
Moore, C.4
Jaffe, T.A.5
Haley, S.6
-
28
-
-
84857101766
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00134056, Acssesed on: January 8, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00134056. Available at http://clinicaltrials.gov (Acssesed on: January 8, 2011).
-
-
-
-
29
-
-
62649134676
-
Safety and efficacy of the specific endothelin-A receptor antagonist ZD4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: A double-blind, placebo-controlled, randomised, phase 2 trial
-
James ND, Caty A, Borre M, Zonnenberg BA, Beuzeboc P, Morris T, et al. Safety and efficacy of the specific endothelin-A receptor antagonist ZD4054 in patients with hormone-resistant prostate cancer and bone metastases who were pain free or mildly symptomatic: A double-blind, placebo-controlled, randomised, phase 2 trial. Eur Urol 2009; 55: 1112-1123.
-
(2009)
Eur Urol
, vol.55
, pp. 1112-1123
-
-
James, N.D.1
Caty, A.2
Borre, M.3
Zonnenberg, B.A.4
Beuzeboc, P.5
Morris, T.6
-
30
-
-
84857105273
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00626548, Acssesed on: January 8, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00626548. Available at http://clinicaltrials.gov (Acssesed on: January 8, 2011).
-
-
-
-
31
-
-
84857106752
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00554229, Acssesed on: January 8, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00554229. Available at http://clinicaltrials.gov (Acssesed on: January 8, 2011).
-
-
-
-
32
-
-
84857105274
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00617669, Acssesed on: January 8, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00617669. Available at http://clinicaltrials.gov (Acssesed on: January 8, 2011).
-
-
-
-
33
-
-
84857106753
-
-
AstraZeneca press release, Accessed on: January 5, 2011
-
AstraZeneca press release. Available at: http://www.astrazeneca.com/ (Accessed on: January 5, 2011).
-
-
-
-
34
-
-
78649997970
-
Receptor activator for nuclear factor kappa B ligand (RANKL) as an osteoimmune key regulator in bone physiology and pathology
-
Narducci P, Bareggi R, Nicolin V. Receptor activator for nuclear factor kappa B ligand (RANKL) as an osteoimmune key regulator in bone physiology and pathology. Acta Histochem 2009; 17: 17.
-
(2009)
Acta Histochem
, vol.17
, pp. 17
-
-
Narducci, P.1
Bareggi, R.2
Nicolin, V.3
-
35
-
-
33846081104
-
The RANK/RANKL/OPG triad in cancer-induced bone diseases
-
Dougall WC, Chaisson M. The RANK/RANKL/OPG triad in cancer-induced bone diseases. Cancer Metastasis Rev 2006;25: 541-549.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 541-549
-
-
Dougall, W.C.1
Chaisson, M.2
-
36
-
-
0037009822
-
A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma
-
Saad F, Gleason DM, Murray R, Tchekmedyian S, Venner P, Lacombe L, et al. A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma. J Natl Cancer Inst 2002; 94:1458-1468.
-
(2002)
J Natl Cancer Inst
, vol.94
, pp. 1458-1468
-
-
Saad, F.1
Gleason, D.M.2
Murray, R.3
Tchekmedyian, S.4
Venner, P.5
Lacombe, L.6
-
37
-
-
2942518111
-
Long-term efficacy of zoledronic acid for the pre vention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
-
Saad F, Gleason DM, Murray R, Tchekmedyian S, Venner P, Lacombe L, et al. Long-term efficacy of zoledronic acid for the pre vention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J Natl Cancer Inst 2004; 96: 879-882.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 879-882
-
-
Saad, F.1
Gleason, D.M.2
Murray, R.3
Tchekmedyian, S.4
Venner, P.5
Lacombe, L.6
-
38
-
-
67649791971
-
Denosumab treatment of prostate cancer with bone metastases and increased urine N-telopeptide levels after therapy with intravenous bisphosphonates: Results of a randomized phase II trial randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates
-
Fizazi K, Bosserman L, Gao G, Skacel T, Markus R, Lipton A, et al. Denosumab treatment of prostate cancer with bone metastases and increased urine N-telopeptide levels after therapy with intravenous bisphosphonates: Results of a randomized phase II trial randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J Urol 2009; 182: 509-515.
-
(2009)
J Urol
, vol.182
, pp. 509-515
-
-
Fizazi, K.1
Bosserman, L.2
Gao, G.3
Skacel, T.4
Markus, R.5
Lipton, A.6
-
39
-
-
63749094012
-
Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates
-
Fizazi K, Lipton A, Mariette X, Body JJ, Rahim Y, Gralow JR, et al. Randomized phase II trial of denosumab in patients with bone metastases from prostate cancer, breast cancer, or other neoplasms after intravenous bisphosphonates. J Clin Oncol 2009; 27: 1564-1571.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1564-1571
-
-
Fizazi, K.1
Lipton, A.2
Mariette, X.3
Body, J.J.4
Rahim, Y.5
Gralow, J.R.6
-
40
-
-
84857106751
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00321620, Acssesed on: January 9, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00321620. Available at http://clinicaltrials.gov (Acssesed on: January 9, 2011).
-
-
-
-
41
-
-
84857105272
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00266091, Acssesed on: Jan 9, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00266091. Available at http://clinicaltrials.gov (Acssesed on: Jan 9, 2011).
-
-
-
-
42
-
-
78650310984
-
-
American Society of Clinical Oncology Annual Meeting. Chicago, USA
-
Fizazi K, Carducci MA, Smith MR, Damião R, Brown JE, Karsh L, et al. A randomized phase III trial of denosumab versus zoledronic acid in patients with bone metastases from castration-resistant prostate cancer. American Society of Clinical Oncology Annual Meeting. Chicago, USA (2010).
-
(2010)
A Randomized Phase III Trial of Denosumab Versus Zoledronic Acid In Patients With Bone Metastases From Castration-resistant Prostate Cancer
-
-
Fizazi, K.1
Carducci, M.A.2
Smith, M.R.3
Damião, R.4
Brown, J.E.5
Karsh, L.6
-
43
-
-
0034772250
-
Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480
-
George DJ, Halabi S, Shepard TF, Vogelzang NJ, Hayes DF, Small EJ, et al. Prognostic significance of plasma vascular endothelial growth factor levels in patients with hormone-refractory prostate cancer treated on Cancer and Leukemia Group B 9480. Clin Cancer Res 2001; 7: 1932-1936.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1932-1936
-
-
George, D.J.1
Halabi, S.2
Shepard, T.F.3
Vogelzang, N.J.4
Hayes, D.F.5
Small, E.J.6
-
44
-
-
53249135560
-
Combination of bevacizumab and docetaxel in docetaxelpretreated hormone-refractory prostate cancer: A phase 2 study
-
Di Lorenzo G, Figg WD, Fossa SD, Mirone V, Autorino R, Longo N, et al. Combination of bevacizumab and docetaxel in docetaxelpretreated hormone-refractory prostate cancer: A phase 2 study. Eur Urol 2008; 54: 1089-1094.
-
(2008)
Eur Urol
, vol.54
, pp. 1089-1094
-
-
Di Lorenzo, G.1
Figg, W.D.2
Fossa, S.D.3
Mirone, V.4
Autorino, R.5
Longo, N.6
-
45
-
-
84857107034
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00110214, Acssesed on: July 10, 2010
-
US Institute of Health, Clinical Trials. gov identifier NCT00110214. Available at http://clinicaltrials.gov (Acssesed on: July 10, 2010).
-
-
-
-
47
-
-
52149110148
-
Sunitinib malate (SU-11248) alone or in combination with low-dose docetaxel inhibits the growth of DU-145 prostate cancer xenografts
-
Cumashi A, Tinari N, Rossi C, Lattanzio R, Natoli C, Piantelli M, et al. Sunitinib malate (SU-11248) alone or in combination with low-dose docetaxel inhibits the growth of DU-145 prostate cancer xenografts. Cancer Lett 2008; 270: 229-233.
-
(2008)
Cancer Lett
, vol.270
, pp. 229-233
-
-
Cumashi, A.1
Tinari, N.2
Rossi, C.3
Lattanzio, R.4
Natoli, C.5
Piantelli, M.6
-
48
-
-
77951887506
-
Sunitinib malate for metastatic castrationresistant prostate cancer following docetaxel-based chemotherapy
-
Sonpavde G, Periman PO, Bernold D, Weckstein D, Fleming MT, Galsky MD, et al. Sunitinib malate for metastatic castrationresistant prostate cancer following docetaxel-based chemotherapy. Ann Oncol 2010; 21: 319-324.
-
(2010)
Ann Oncol
, vol.21
, pp. 319-324
-
-
Sonpavde, G.1
Periman, P.O.2
Bernold, D.3
Weckstein, D.4
Fleming, M.T.5
Galsky, M.D.6
-
49
-
-
84857101764
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00676650, Acssesed on: January 10, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00676650. Available at http://clinicaltrials.gov (Acssesed on: January 10, 2011).
-
-
-
-
50
-
-
74949119167
-
Phase I study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors
-
Lockhart AC, Rothenberg ML, Dupont J, Cooper W, Chevalier P, Sternas L, et al. Phase I study of intravenous vascular endothelial growth factor trap, aflibercept, in patients with advanced solid tumors. J Clin Oncol 2010; 28: 207-214.
-
(2010)
J Clin Oncol
, vol.28
, pp. 207-214
-
-
Lockhart, A.C.1
Rothenberg, M.L.2
Dupont, J.3
Cooper, W.4
Chevalier, P.5
Sternas, L.6
-
51
-
-
74949101370
-
Phase 1 study of aflibercept administered subcutaneously to patients with advanced solid tumors
-
Tew WP, Gordon M, Murren J, Dupont J, Pezzulli S, Aghajanian C, et al. Phase 1 study of aflibercept administered subcutaneously to patients with advanced solid tumors. Clin Cancer Res 2010; 16: 358-366.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 358-366
-
-
Tew, W.P.1
Gordon, M.2
Murren, J.3
Dupont, J.4
Pezzulli, S.5
Aghajanian, C.6
-
52
-
-
84857107035
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00519285, Acssesed on: January 10, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00519285. Available at http://clinicaltrials.gov (Acssesed on: January 10, 2011).
-
-
-
-
53
-
-
33845394305
-
Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer
-
Isaacs JT, Pili R, Qian DZ, Dalrymple SL, Garrison JB, Kyprianou N, et al. Identification of ABR-215050 as lead second generation quinoline-3-carboxamide anti-angiogenic agent for the treatment of prostate cancer. Prostate 2006; 66: 1768-1778.
-
(2006)
Prostate
, vol.66
, pp. 1768-1778
-
-
Isaacs, J.T.1
Pili, R.2
Qian, D.Z.3
Dalrymple, S.L.4
Garrison, J.B.5
Kyprianou, N.6
-
54
-
-
34248192988
-
The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts
-
Dalrymple SL, Becker RE, Isaacs JT. The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts. Prostate 2007; 67: 790-797.
-
(2007)
Prostate
, vol.67
, pp. 790-797
-
-
Dalrymple, S.L.1
Becker, R.E.2
Isaacs, J.T.3
-
55
-
-
77952223624
-
Tasquinimod (ABR-215050), a quinoline-3-carboxamide antiangiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
-
Olsson A, Bjork A, Vallon-Christersson J, Isaacs JT, Leanderson T. Tasquinimod (ABR-215050), a quinoline-3-carboxamide antiangiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. Mol Cancer 2010; 9: 107.
-
(2010)
Mol Cancer
, vol.9
, pp. 107
-
-
Olsson, A.1
Bjork, A.2
Vallon-Christersson, J.3
Isaacs, J.T.4
Leanderson, T.5
-
56
-
-
70349952393
-
Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer
-
Bratt O, Haggman M, Ahlgren G, Nordle O, Bjork A, Damber JE. Open-label, clinical phase I studies of tasquinimod in patients with castration-resistant prostate cancer. Br J Cancer 2009; 101: 1233-1240.
-
(2009)
Br J Cancer
, vol.101
, pp. 1233-1240
-
-
Bratt, O.1
Haggman, M.2
Ahlgren, G.3
Nordle, O.4
Bjork, A.5
Damber, J.E.6
-
57
-
-
84857101515
-
-
American Society of Clinical Oncology Annual Meeting. Chicago, USA
-
Pili R, Haggman M, Stadler WM, Gingrich JR, Assikis VJ, Björk A, et al. A randomized, multicenter, international phase II study of tasquinimod in chemotherapy naïve patients with metastatic castrate-resistant prostate cancer (CRPC). American Society of Clinical Oncology Annual Meeting. Chicago, USA (2010).
-
(2010)
A Randomized, Multicenter, International Phase II Study of Tasquinimod In Chemotherapy Naïve Patients With Metastatic Castrate-resistant Prostate Cancer (CRPC)
-
-
Pili, R.1
Haggman, M.2
Stadler, W.M.3
Gingrich, J.R.4
Assikis, V.J.5
Björk, A.6
-
58
-
-
66149164441
-
SRC family kinase activity is up-regulated in hormonerefractory prostate cancer
-
Tatarov O, Mitchell TJ, Seywright M, Leung HY, Brunton VG, Edwards J. SRC family kinase activity is up-regulated in hormonerefractory prostate cancer. Clin Cancer Res 2009; 15: 3540-3549.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3540-3549
-
-
Tatarov, O.1
Mitchell, T.J.2
Seywright, M.3
Leung, H.Y.4
Brunton, V.G.5
Edwards, J.6
-
59
-
-
27144547509
-
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
-
Nam S, Kim D, Cheng JQ, Zhang S, Lee JH, Buettner R, et al. Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res 2005; 65: 9185-9189.
-
(2005)
Cancer Res
, vol.65
, pp. 9185-9189
-
-
Nam, S.1
Kim, D.2
Cheng, J.Q.3
Zhang, S.4
Lee, J.H.5
Buettner, R.6
-
60
-
-
67650601930
-
Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis
-
Koreckij T, Nguyen H, Brown LG, Yu EY, Vessella RL, Corey E. Dasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis. Br J Cancer 2009; 101: 263-268.
-
(2009)
Br J Cancer
, vol.101
, pp. 263-268
-
-
Koreckij, T.1
Nguyen, H.2
Brown, L.G.3
Yu, E.Y.4
Vessella, R.L.5
Corey, E.6
-
61
-
-
73149115110
-
Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer
-
Yu EY, Wilding G, Posadas E, Gross M, Culine S, Massard C, et al. Phase II study of dasatinib in patients with metastatic castration-resistant prostate cancer. Clin Cancer Res 2009; 15: 7421-7428.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7421-7428
-
-
Yu, E.Y.1
Wilding, G.2
Posadas, E.3
Gross, M.4
Culine, S.5
Massard, C.6
-
62
-
-
84857105270
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00744497, Acssesed on: January 10, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00744497. Available at http://clinicaltrials.gov (Acssesed on: January 10, 2011).
-
-
-
-
64
-
-
73949094777
-
Clusterin (CLU) and prostate cancer
-
Rizzi F, Bettuzzi S. Clusterin (CLU) and prostate cancer. Adv Cancer Res 2009; 105: 1-19.
-
(2009)
Adv Cancer Res
, vol.105
, pp. 1-19
-
-
Rizzi, F.1
Bettuzzi, S.2
-
65
-
-
76749144766
-
Targeting the cytoprotective chaperone, clusterin, for treatment of advanced cancer
-
Zoubeidi A, Chi K, Gleave M. Targeting the cytoprotective chaperone, clusterin, for treatment of advanced cancer. Clin Cancer Res 2010; 16: 1088-1093.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1088-1093
-
-
Zoubeidi, A.1
Chi, K.2
Gleave, M.3
-
66
-
-
77957957234
-
Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer
-
Chi KN, Hotte SJ, Yu EY, Tu D, Eigl BJ, Tannock I, et al. Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer. J Clin Oncol 2010; 28: 4247-4254.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4247-4254
-
-
Chi, K.N.1
Hotte, S.J.2
Yu, E.Y.3
Tu, D.4
Eigl, B.J.5
Tannock, I.6
-
67
-
-
84857105271
-
-
US Institute of Health, Clinical Trials. gov identifier NCT01188187, Acssesed on: January 10, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT01188187. Available at http://clinicaltrials.gov (Acssesed on: January 10, 2011).
-
-
-
-
68
-
-
84857106749
-
-
US Institute of Health, Clinical Trials. gov identifier NCT01083615, Acssesed on: January 10, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT01083615. Available at http://clinicaltrials.gov (Acssesed on: January 10, 2011).
-
-
-
-
69
-
-
0034064991
-
Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels
-
Tudor G, Aguilera A, Halverson DO, Laing ND, Sausville EA. Susceptibility to drug-induced apoptosis correlates with differential modulation of Bad, Bcl-2 and Bcl-xL protein levels. Cell Death Differ 2000; 7: 574-586.
-
(2000)
Cell Death Differ
, vol.7
, pp. 574-586
-
-
Tudor, G.1
Aguilera, A.2
Halverson, D.O.3
Laing, N.D.4
Sausville, E.A.5
-
70
-
-
0027093255
-
Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgenindependent prostate cancer
-
McDonnell TJ, Troncoso P, Brisbay SM, Logothetis C, Chung LW, Hsieh JT, et al. Expression of the protooncogene bcl-2 in the prostate and its association with emergence of androgenindependent prostate cancer. Cancer Res 1992; 52: 6940-6944.
-
(1992)
Cancer Res
, vol.52
, pp. 6940-6944
-
-
McDonnell, T.J.1
Troncoso, P.2
Brisbay, S.M.3
Logothetis, C.4
Chung, L.W.5
Hsieh, J.T.6
-
71
-
-
65649130832
-
An open-label, multicenter, phase I/II study of single-agent AT-101 in men with castrate-resistant prostate cancer
-
Liu G, Kelly WK, Wilding G, Leopold L, Brill K, Somer B. An open-label, multicenter, phase I/II study of single-agent AT-101 in men with castrate-resistant prostate cancer. Clin Cancer Res 2009; 15: 3172-3176.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3172-3176
-
-
Liu, G.1
Kelly, W.K.2
Wilding, G.3
Leopold, L.4
Brill, K.5
Somer, B.6
-
72
-
-
80052334202
-
-
American Society of Clinical Oncology Annual Meeting. Orlando, USA
-
MacVicar GR, Greco A, Reeves J, Maleski J, Holmlund J, Leopold L. An open -label, multicenter, phase I/II study of AT-101 in combination with docetaxel (D) and predonisone (P) in men with castrate-resistant prostate cancer (CRPC). American Society of Clinical Oncology Annual Meeting. Orlando, USA (2009).
-
(2009)
An Open -label, Multicenter, Phase I/II Study of AT-101 In Combination With Docetaxel (D) and Predonisone (P) In Men With Castrate-resistant Prostate Cancer (CRPC)
-
-
Macvicar, G.R.1
Greco, A.2
Reeves, J.3
Maleski, J.4
Holmlund, J.5
Leopold, L.6
-
73
-
-
84857106750
-
-
US Institute of Health, Clinical Trials. gov identifier NCT00571675, Acssesed on: January 10, 2011
-
US Institute of Health, Clinical Trials. gov identifier NCT00571675. Available at http://clinicaltrials.gov (Acssesed on: January 10, 2011).
-
-
-
-
74
-
-
59449102526
-
Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors
-
Mita AC, Denis LJ, Rowinsky EK, Debono JS, Goetz AD, Ochoa L, et al. Phase I and pharmacokinetic study of XRP6258 (RPR 116258A), a novel taxane, administered as a 1-hour infusion every 3 weeks in patients with advanced solid tumors. Clin Cancer Res 2009; 15: 723-730.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 723-730
-
-
Mita, A.C.1
Denis, L.J.2
Rowinsky, E.K.3
Debono, J.S.4
Goetz, A.D.5
Ochoa, L.6
-
75
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, Kocak I, et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial. Lancet 2010; 376: 1147-1154.
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
de Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
Hansen, S.4
Machiels, J.P.5
Kocak, I.6
-
76
-
-
73949119171
-
Epothilones: Tubulin polymerization as a novel target for prostate cancer therapy
-
Lee JJ, Kelly WK. Epothilones: Tubulin polymerization as a novel target for prostate cancer therapy. Nat Clin Pract Oncol 2009; 6: 85-92.
-
(2009)
Nat Clin Pract Oncol
, vol.6
, pp. 85-92
-
-
Lee, J.J.1
Kelly, W.K.2
-
77
-
-
33644843604
-
Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormonerefractory prostate cancer: A Southwest Oncology Group trial S0111
-
Hussain M, Tangen CM, Lara PN, Jr., Vaishampayan UN, Petrylak DP, Colevas AD, et al. Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormonerefractory prostate cancer: A Southwest Oncology Group trial S0111. J Clin Oncol 2005; 23: 8724-8729.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8724-8729
-
-
Hussain, M.1
Tangen, C.M.2
Lara Jr., P.N.3
Vaishampayan, U.N.4
Petrylak, D.P.5
Colevas, A.D.6
-
78
-
-
34547119271
-
Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients: Randomized phase 2 study of ixabepilone or mitoxantrone and prednisone
-
Rosenberg JE, Weinberg VK, Kelly WK, Michaelson D, Hussain MH, Wilding G, et al. Activity of second-line chemotherapy in docetaxel-refractory hormone-refractory prostate cancer patients: Randomized phase 2 study of ixabepilone or mitoxantrone and prednisone. Cancer 2007; 110: 556-563.
-
(2007)
Cancer
, vol.110
, pp. 556-563
-
-
Rosenberg, J.E.1
Weinberg, V.K.2
Kelly, W.K.3
Michaelson, D.4
Hussain, M.H.5
Wilding, G.6
-
79
-
-
61649126264
-
Phase II trial of weekly patupilone in patients with castration-resistant prostate cancer
-
Hussain A, DiPaola RS, Baron AD, Higano CS, Tchekmedyian NS, Johri AR. Phase II trial of weekly patupilone in patients with castration-resistant prostate cancer. Ann Oncol 2009; 20: 492-497.
-
(2009)
Ann Oncol
, vol.20
, pp. 492-497
-
-
Hussain, A.1
Dipaola, R.S.2
Baron, A.D.3
Higano, C.S.4
Tchekmedyian, N.S.5
Johri, A.R.6
-
80
-
-
80052342268
-
-
American Society of Clinical Oncology Annual Meeting. Orlando, USA
-
Beardsley EK, Saad F, Eigl B, Venner P, Hotte S, Winquist E, et al. A phase II study of patupilone in patients (PTS) with metastatic castration-resistant prostate cancer (CRPC) who have progressed after docetaxel. American Society of Clinical Oncology Annual Meeting. Orlando, USA (2009).
-
(2009)
A Phase II Study of Patupilone In Patients (PTS) With Metastatic Castration-resistant Prostate Cancer (CRPC) Who Have Progressed After Docetaxel
-
-
Beardsley, E.K.1
Saad, F.2
Eigl, B.3
Venner, P.4
Hotte, S.5
Winquist, E.6
-
81
-
-
8644219658
-
Phase II study of oral bis (aceto) ammine dichloro (cyclohexamine) platinum (IV) (JM-216, BMS-182751) given daily x 5 in hormone refractory prostate cancer (HRPC)
-
Latif T, Wood L, Connell C, Smith DC, Vaughn D, Lebwohl D, et al. Phase II study of oral bis (aceto) ammine dichloro (cyclohexamine) platinum (IV) (JM-216, BMS-182751) given daily x 5 in hormone refractory prostate cancer (HRPC). Invest New Drugs 2005; 23: 79-84.
-
(2005)
Invest New Drugs
, vol.23
, pp. 79-84
-
-
Latif, T.1
Wood, L.2
Connell, C.3
Smith, D.C.4
Vaughn, D.5
Lebwohl, D.6
-
82
-
-
73949098659
-
Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: The SPARC trial
-
Sternberg CN, Petrylak DP, Sartor O, Witjes JA, Demkow T, Ferrero JM, et al. Multinational, double-blind, phase III study of prednisone and either satraplatin or placebo in patients with castrate-refractory prostate cancer progressing after prior chemotherapy: The SPARC trial. J Clin Oncol 2009; 27: 5431-5438.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5431-5438
-
-
Sternberg, C.N.1
Petrylak, D.P.2
Sartor, O.3
Witjes, J.A.4
Demkow, T.5
Ferrero, J.M.6
-
83
-
-
80052328998
-
-
American Society of Clinical Oncology Genitourinary Cancers Symposium. San Francisco, USA
-
De Jager RL, Roman LD, Lopatkin NA, Karlov PA, Breitz HB, Earhart RH, et al. Phase II study of picoplatin with docetaxel and predonisone in first-line treatment of castration-resistant prostate cancer (CRPC). American Society of Clinical Oncology Genitourinary Cancers Symposium. San Francisco, USA (2010).
-
(2010)
Phase II Study of Picoplatin With Docetaxel and Predonisone In First-line Treatment of Castration-resistant Prostate Cancer (CRPC)
-
-
de Jager, R.L.1
Roman, L.D.2
Lopatkin, N.A.3
Karlov, P.A.4
Breitz, H.B.5
Earhart, R.H.6
-
84
-
-
0034554863
-
Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
-
Small EJ, Fratesi P, Reese DM, Strang G, Laus R, Peshwa MV, et al. Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells. J Clin Oncol 2000; 18: 3894-3903.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3894-3903
-
-
Small, E.J.1
Fratesi, P.2
Reese, D.M.3
Strang, G.4
Laus, R.5
Peshwa, M.V.6
-
85
-
-
33746012881
-
Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer
-
Small EJ, Schellhammer PF, Higano CS, Redfern CH, Nemunaitis JJ, Valone FH, et al. Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer. J Clin Oncol 2006; 24: 3089-3094.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3089-3094
-
-
Small, E.J.1
Schellhammer, P.F.2
Higano, C.S.3
Redfern, C.H.4
Nemunaitis, J.J.5
Valone, F.H.6
-
86
-
-
68549135290
-
Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
-
Higano CS, Schellhammer PF, Small EJ, Burch PA, Nemunaitis J, Yuh L, et al. Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer. Cancer 2009; 115: 3670-3679.
-
(2009)
Cancer
, vol.115
, pp. 3670-3679
-
-
Higano, C.S.1
Schellhammer, P.F.2
Small, E.J.3
Burch, P.A.4
Nemunaitis, J.5
Yuh, L.6
-
87
-
-
77955066199
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff PW, Higano CS, Shore ND, Berger ER, Small EJ, Penson DF, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010; 363: 411-422.
-
(2010)
N Engl J Med
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
-
88
-
-
84857105485
-
-
Accessed on: January 11, 2011
-
Northwest Biotherapeutics. Available at: http://www.nwbio.com/clinical_dcvax_prostate.php. (Accessed on: January 11, 2011).
-
Northwest Biotherapeutics
-
-
-
89
-
-
30544449854
-
A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer
-
DiPaola RS, Plante M, Kaufman H, Petrylak DP, Israeli R, Lattime E, et al. A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer. J Transl Med 2006; 4: 1-5.
-
(2006)
J Transl Med
, vol.4
, pp. 1-5
-
-
Dipaola, R.S.1
Plante, M.2
Kaufman, H.3
Petrylak, D.P.4
Israeli, R.5
Lattime, E.6
-
90
-
-
34548452131
-
Clinical safety of a viral vector based prostate cancer vaccine strategy
-
Arlen PM, Skarupa L, Pazdur M, Seetharam M, Tsang KY, Grosenbach DW, et al. Clinical safety of a viral vector based prostate cancer vaccine strategy. J Urol 2007; 178: 1515-1520.
-
(2007)
J Urol
, vol.178
, pp. 1515-1520
-
-
Arlen, P.M.1
Skarupa, L.2
Pazdur, M.3
Seetharam, M.4
Tsang, K.Y.5
Grosenbach, D.W.6
-
91
-
-
77950473925
-
Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer
-
Gulley JL, Arlen PM, Madan RA, Tsang KY, Pazdur MP, Skarupa L, et al. Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer. Cancer Immunol Immunother 2010; 59: 663-674.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 663-674
-
-
Gulley, J.L.1
Arlen, P.M.2
Madan, R.A.3
Tsang, K.Y.4
Pazdur, M.P.5
Skarupa, L.6
-
92
-
-
77949895922
-
Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer
-
Kantoff PW, Schuetz TJ, Blumenstein BA, Glode LM, Bilhartz DL, Wyand M, et al. Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer. J Clin Oncol 2010; 28: 1099-1105.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1099-1105
-
-
Kantoff, P.W.1
Schuetz, T.J.2
Blumenstein, B.A.3
Glode, L.M.4
Bilhartz, D.L.5
Wyand, M.6
-
94
-
-
62549119511
-
Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing
-
Bharadwaj AG, Kovar JL, Loughman E, Elowsky C, Oakley GG, Simpson MA. Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing. Am J Pathol 2009; 174: 1027-1036.
-
(2009)
Am J Pathol
, vol.174
, pp. 1027-1036
-
-
Bharadwaj, A.G.1
Kovar, J.L.2
Loughman, E.3
Elowsky, C.4
Oakley, G.G.5
Simpson, M.A.6
-
96
-
-
76949095336
-
The role of caveolin-1 in prostate cancer: Clinical implications
-
Thompson TC, Tahir SA, Li L, Watanabe M, Naruishi K, Yang G, et al. The role of caveolin-1 in prostate cancer: Clinical implications. Prostate Cancer Prostatic Dis. 2010;13: 6-11.
-
(2010)
Prostate Cancer Prostatic Dis
, vol.13
, pp. 6-11
-
-
Thompson, T.C.1
Tahir, S.A.2
Li, L.3
Watanabe, M.4
Naruishi, K.5
Yang, G.6
-
97
-
-
80052305409
-
-
WO2010012452
-
Cato, A.B.C., Shatkina, L., Jehle, K., Maddalo, D. Bag-1 peptide that inhibits prostate cancer. WO2010012452 (2010).
-
(2010)
Bag-1 Peptide That Inhibits Prostate Cancer
-
-
Cato, A.B.C.1
Shatkina, L.2
Jehle, K.3
Maddalo, D.4
-
98
-
-
80052336788
-
-
AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics. Boston, USA
-
Maddalo D, Neeb A, Jehle K, Shatkina L, Cato A. Heat shock proteins: Distinct peptides derived from the cochaperone Bag-1L inhibit prostate cancer cell growth. AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics. Boston, USA (2009).
-
(2009)
Heat Shock Proteins: Distinct Peptides Derived From the Cochaperone Bag-1L Inhibit Prostate Cancer Cell Growth
-
-
Maddalo, D.1
Neeb, A.2
Jehle, K.3
Shatkina, L.4
Cato, A.5
-
100
-
-
77953576511
-
N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer
-
Jennbacken K, Tesan T, Wang W, Gustavsson H, Damber JE, Welen K. N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer. Endocr Relat Cancer 2010; 17: 469-479.
-
(2010)
Endocr Relat Cancer
, vol.17
, pp. 469-479
-
-
Jennbacken, K.1
Tesan, T.2
Wang, W.3
Gustavsson, H.4
Damber, J.E.5
Welen, K.6
-
102
-
-
65549168746
-
A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth
-
Guo Z, Yang X, Sun F, Jiang R, Linn DE, Chen H, et al. A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth. Cancer Res 2009; 69: 2305-2313.
-
(2009)
Cancer Res
, vol.69
, pp. 2305-2313
-
-
Guo, Z.1
Yang, X.2
Sun, F.3
Jiang, R.4
Linn, D.E.5
Chen, H.6
-
104
-
-
80052337372
-
-
US7807373
-
Srivastava, S., Moul, J. W, Srikantan, V., Zou, Z. Prostate-specific gene, PCGEM1, and the methods of using PCGEM1 to detect, treat, and prevent prostate cancer. US7807373 (2010).
-
(2010)
Prostate-specific Gene, PCGEM1, and The Methods of Using PCGEM1 to Detect, Treat, and Prevent Prostate Cancer
-
-
Srivastava, S.1
Moul, J.W.2
Srikantan, V.3
Zou, Z.4
-
105
-
-
33645532828
-
Regulation of apoptosis by a prostate-specific and prostate cancerassociated noncoding gene, PCGEM1
-
Fu X, Ravindranath L, Tran N, Petrovics G, Srivastava S. Regulation of apoptosis by a prostate-specific and prostate cancerassociated noncoding gene, PCGEM1. DNA Cell Biol 2006; 25: 135-141.
-
(2006)
DNA Cell Biol
, vol.25
, pp. 135-141
-
-
Fu, X.1
Ravindranath, L.2
Tran, N.3
Petrovics, G.4
Srivastava, S.5
-
106
-
-
77956896027
-
LNCaP Atlas: Gene expression associated with in vivo progression to castration-recurrent prostate cancer
-
Romanuik TL, Wang G, Morozova O, Delaney A, Marra MA, Sadar MD. LNCaP Atlas: Gene expression associated with in vivo progression to castration-recurrent prostate cancer. BMC Med Genomics 2010; 3: 43.
-
(2010)
BMC Med Genomics
, vol.3
, pp. 43
-
-
Romanuik, T.L.1
Wang, G.2
Morozova, O.3
Delaney, A.4
Marra, M.A.5
Sadar, M.D.6
|