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Volumn 11, Issue 8, 2011, Pages 1253-1263

Current role and safety profile of aromatase inhibitors in early breast cancer

Author keywords

adjuvant therapy; aromatase inhibitors; breast cancer; estrogens; tamoxifen

Indexed keywords

25 HYDROXYVITAMIN D; AMINOGLUTETHIMIDE; ANASTROZOLE; AROMATASE INHIBITOR; ESTROGEN RECEPTOR; EXEMESTANE; FADROZOLE; FORMESTANE; GABAPENTIN; GONADORELIN DERIVATIVE; LETROZOLE; PLACEBO; PRASTERONE; PROGESTERONE RECEPTOR; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TAMOXIFEN; ZOLEDRONIC ACID;

EID: 80052312353     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/era.11.96     Document Type: Review
Times cited : (28)

References (62)
  • 1
    • 0038688478 scopus 로고    scopus 로고
    • Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer databases
    • Bardou VJ, Arpino G, Elledge RM et al. Progesterone receptor status significantly improves outcome prediction over estrogen receptor status alone for adjuvant endocrine therapy in two large breast cancer databases. J. Clin. Oncol. 21, 1973-1979 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1973-1979
    • Bardou, V.J.1    Arpino, G.2    Elledge, R.M.3
  • 2
    • 78649825336 scopus 로고    scopus 로고
    • Current and emerging biomarkers in breast cancer: Prognosis and prediction
    • Weigel MT, Dowsett M. Current and emerging biomarkers in breast cancer: Prognosis and prediction. Endocr. Relat. Cancer 17(4), R245-R262 (2010).
    • (2010) Endocr. Relat. Cancer , vol.17 , Issue.4
    • Weigel, M.T.1    Dowsett, M.2
  • 3
    • 77955923386 scopus 로고    scopus 로고
    • Molecular therapy of breast cancer: Progress and future directions
    • Lin SX, Chen J, Mazumdar M et al. Molecular therapy of breast cancer: Progress and future directions. Nat. Rev. Endocrinol. 6(9), 485-493 (2010).
    • (2010) Nat. Rev. Endocrinol. , vol.6 , Issue.9 , pp. 485-493
    • Lin, S.X.1    Chen, J.2    Mazumdar, M.3
  • 4
    • 33947246190 scopus 로고    scopus 로고
    • Predictors of early recurrence in postmenopausal women with operable breast cancer
    • (Abstract 2091 100(Suppl. 1) (2006) (Abstract 2091).
    • Mansell J, Monypenny IJ, Skene AI et al. Predictors of early recurrence in postmenopausal women with operable breast cancer. Breast Cancer Res. Treat 100(Suppl. 1) 2006) (Abstract 2091 100(Suppl. 1) (2006) (Abstract 2091).
    • (2006) Breast Cancer Res. Treat , vol.100 , Issue.SUPPL. 1
    • Mansell, J.1    Monypenny, I.J.2    Skene, A.I.3
  • 5
    • 5044223956 scopus 로고    scopus 로고
    • A review of adjuvant hormonal therapy in breast cancer
    • Jones KL, Buzdar AU. A review of adjuvant hormonal therapy in breast cancer. Endocr. Relat. Cancer 11, 391-406 (2004).
    • (2004) Endocr. Relat. Cancer , vol.11 , pp. 391-406
    • Jones, K.L.1    Buzdar, A.U.2
  • 6
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: An overview of the randomised trials. Lancet 351, 1451-1467 (1998).
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 7
    • 38849158565 scopus 로고    scopus 로고
    • GeislerJ. Aromatase inhibitors: Assessment of biochemical efficacy measured by total body aromatase inhibition and tissue estrogen suppression
    • 19
    • Lenning PE, GeislerJ. Aromatase inhibitors: Assessment of biochemical efficacy measured by total body aromatase inhibition and tissue estrogen suppression. J. Steroid Biochem. Mol. Biol. 108(3-5), 19, 600-602 (2008).
    • (2008) J. Steroid Biochem. Mol. Biol. , vol.108 , Issue.3-5 , pp. 600-602
    • Lenning, P.E.1
  • 8
    • 33748036987 scopus 로고    scopus 로고
    • Defining the role of aromatase inhibitors in the adjuvant endocrine treatment of early breast cancer
    • Buzdar A, Chlebowski R, Cuzick J et al. Defining the role of aromatase inhibitors in the adjuvant endocrine treatment of early breast cancer. Curr. Med. Res. Opin. 22(8), 1575-1585 2006)
    • (2006) Curr. Med. Res. Opin. , vol.22 , Issue.8 , pp. 1575-1585
    • Buzdar, A.1    Chlebowski, R.2    Cuzick, J.3
  • 9
    • 0037157603 scopus 로고    scopus 로고
    • ATAC Trialists' Group. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial
    • Baum M, Budzar AU, Cuzick J et al. ATAC Trialists' Group. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: First results of the ATAC randomised trial. Lancet 359, 2131-2139 (2002).
    • (2002) Lancet , vol.359 , pp. 2131-2139
    • Baum, M.1    Budzar, A.U.2    Cuzick, J.3
  • 10
    • 0142181118 scopus 로고    scopus 로고
    • The ATAC (Arimidex, Tamoxifen Alone or in Combination) Trialists' Group. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses
    • Baum M, Buzdar A, Cuzick J et al. The ATAC (Arimidex, Tamoxifen Alone or in Combination) Trialists' Group. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses. Cancer 98, 1802-1810 (2003).
    • (2003) Cancer , vol.98 , pp. 1802-1810
    • Baum, M.1    Buzdar, A.2    Cuzick, J.3
  • 11
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of years' adjuvant treatment for breast cancer
    • ATAC Trialists' Group Cornerstone article showing the superiority of the aromatase inhibitor (AI) anastrazole in early breast cancer.
    • Howell A, Cuzick J, Baum M et al. ATAC Trialists' Group. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of years' adjuvant treatment for breast cancer. Lancet 365, 60-62 (2005). Cornerstone article showing the superiority of the aromatase inhibitor (AI) anastrazole in early breast cancer.
    • (2005) Lancet , vol.365 , pp. 60-62
    • Howell, A.1    Cuzick, J.2    Baum, M.3
  • 12
    • 37449028688 scopus 로고    scopus 로고
    • Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial
    • Forbes JF, Cuzick J, Buzdar A et al. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. Lancet Oncol. 9, 45-53 (2008).
    • (2008) Lancet Oncol , vol.9 , pp. 45-53
    • Forbes, J.F.1    Cuzick, J.2    Buzdar, A.3
  • 13
    • 29544433211 scopus 로고    scopus 로고
    • A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer
    • for the Breast International Group (BIG) 1-98 Collaborative Group First study showing the superiority of the AI letrozole in terms of reduction of relapse at the metastatic site
    • Thurlimann B, Keshaviah A, Coates AS et al.; for the Breast International Group (BIG) 1-98 Collaborative Group. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N. Engl. J. Med. 353, 2747-2757 (2005). First study showing the superiority of the AI letrozole in terms of reduction of relapse at the metastatic site.
    • (2005) N. Engl. J. Med. , vol.353 , pp. 2747-2757
    • Thurlimann, B.1    Keshaviah, A.2    Coates, A.S.3
  • 14
    • 33947510501 scopus 로고    scopus 로고
    • Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrineresponsive early breast cancer: Update of study BIG 1-98
    • Coates AS, Keshaviah A, Thurlimann B et al. Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrineresponsive early breast cancer: Update of study BIG 1-98. J. Clin. Oncol. 25, 486-492 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 486-492
    • Coates, A.S.1    Keshaviah, A.2    Thurlimann, B.3
  • 15
    • 65749105712 scopus 로고    scopus 로고
    • BIG 1-98: A randomized doubleblind phase III study evaluating letrozole and tamoxifen given in sequence as adjuvant endocrine therapy for postmenopausal women with receptorpositive breast cancer
    • (Abstract 13
    • Mouridsen H, Giobbie-Hurder A, Mauriac L et al. BIG 1-98: A randomized doubleblind phase III study evaluating letrozole and tamoxifen given in sequence as adjuvant endocrine therapy for postmenopausal women with receptorpositive breast cancer. Proc. SABCS (2008) (Abstract 13).
    • (2008) Proc. SABCS
    • Mouridsen, H.1    Giobbie-Hurder, A.2    Mauriac, L.3
  • 16
    • 78649703310 scopus 로고    scopus 로고
    • Central Review of ER, PgR and HER2 in BIG 1-98 evaluating letrozole vs. letrozole followed by tamoxifen vs. tamoxifen followed by letrozole as adjuvant endocrine therapy for postmenopausal women with hormone receptor-positive breast cancer
    • (Abstract 76
    • Viale G, Regan MM, Dell'Orto P et al. Central Review of ER, PgR and HER2 in BIG 1-98 evaluating letrozole vs. letrozole followed by tamoxifen vs. tamoxifen followed by letrozole as adjuvant endocrine therapy for postmenopausal women with hormone receptor-positive breast cancer. Proc. SABCS (2009) (Abstract 76).
    • (2009) Proc. SABCS
    • Viale, G.1    Regan, M.M.2    Dell'Orto, P.3
  • 17
    • 78649297387 scopus 로고    scopus 로고
    • Five years of exemestane as initial therapy compared to 5 years of tamoxifen followed by exemestane: The TEAM trial, a prospective, randomized, phase III trial in postmenopausal women with hormonesensitive early breast cancer
    • (Abstract 11
    • Rea D, Hasenburg A, Seynaeve C et al. Five years of exemestane as initial therapy compared to 5 years of tamoxifen followed by exemestane: The TEAM trial, a prospective, randomized, phase III trial in postmenopausal women with hormonesensitive early breast cancer. Proc. SABCS (2009) (Abstract 11).
    • (2009) Proc. SABCS
    • Rea, D.1    Hasenburg, A.2    Seynaeve, C.3
  • 18
    • 33751321384 scopus 로고    scopus 로고
    • Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormonesensitive early-stage breast cancer: A meta-analysis
    • Jonat W, Gnant M, Boccardo F et al. Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormonesensitive early-stage breast cancer: A meta-analysis. Lancet Oncol. 7, 991-996 (2010).
    • (2010) Lancet Oncol. , vol.7 , pp. 991-996
    • Jonat, W.1    Gnant, M.2    Boccardo, F.3
  • 19
    • 10744223655 scopus 로고    scopus 로고
    • Intergroup Exemestane Study. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
    • Coombes RC, Hall E, Gibson LJ et al. Intergroup Exemestane Study. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N. Engl. J. Med. 350, 1081-1092 2004
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1081-1092
    • Coombes, R.C.1    Hall, E.2    Gibson, L.J.3
  • 20
    • 33846545851 scopus 로고    scopus 로고
    • Intergroup exemestane study. Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup exemestane study): A randomised controlled trial
    • Coombes RC, Kilburn LS, Snowdon CF et al. Intergroup exemestane study. Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup exemestane study): A randomised controlled trial. Lancet 369, 559-570 (2007).
    • (2007) Lancet , vol.369 , pp. 559-570
    • Coombes, R.C.1    Kilburn, L.S.2    Snowdon, C.F.3
  • 21
    • 2442684453 scopus 로고    scopus 로고
    • Ten-year outcomes in a population-based cohort of node-negative, lymphatic, and vascular invasion negative early breast cancers without adjuvant systemic therapies
    • Chia SK, Speers CH, Bryce CJ et al. Ten-year outcomes in a population-based cohort of node-negative, lymphatic, and vascular invasion negative early breast cancers without adjuvant systemic therapies. J. Clin. Oncol. 22, 1630-1637 (2004).
    • (2004) J. Clin. Oncol. , vol.22 , pp. 1630-1637
    • Chia, S.K.1    Speers, C.H.2    Bryce, C.J.3
  • 22
    • 63849184380 scopus 로고    scopus 로고
    • On behalf of the collaboration. adjuvant tamoxifen, longer against shorter: International randomized trial of 10 versus 5 years of adjuvant tamoxifen among 11 500 women: Preliminary results
    • (Abstract 48
    • Peto R, Davies C; on behalf of the Collaboration. Adjuvant Tamoxifen, Longer Against Shorter: International randomized trial of 10 versus 5 years of adjuvant tamoxifen among 11 500 women: Preliminary results. Proc. SABCS (2007) (Abstract 48).
    • (2007) Proc. SABCS
    • Peto, R.1    Davies, C.2
  • 23
    • 7444259675 scopus 로고    scopus 로고
    • A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer
    • Goss PE, Ingle JN, Martino S, et al. A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N. Engl. J. Med. 349, 1793-1802 (2003).
    • (2003) N. Engl. J. Med. , vol.349 , pp. 1793-1802
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 24
    • 24744450378 scopus 로고    scopus 로고
    • Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17
    • Goss PE, Ingle JN, Martino S et al. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17. J. Natl Cancer Inst. 97, 1262-1271 (2005).
    • (2005) J. Natl Cancer Inst. , vol.97 , pp. 1262-1271
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 25
    • 34247864457 scopus 로고    scopus 로고
    • Benefit from exemestane (EXE) as extended adjuvant therapy after 5 years of tamoxifen (TAM): Intent-to-treat analysis of NSABP B-33
    • (Abstract 49).
    • Mamounas E, Jeong J-H, Wickerham L et al. Benefit from exemestane (EXE) as extended adjuvant therapy after 5 years of tamoxifen (TAM): Intent-to-treat analysis of NSABP B-33. Breast Cancer Res. Treat 100(Suppl. 1), S22 (2006) (Abstract 49).
    • (2006) Breast Cancer Res. Treat , vol.100 , Issue.SUPPL. 1
    • Mamounas, E.1    Jeong, J-.H.2    Wickerham, L.3
  • 26
    • 1542359096 scopus 로고    scopus 로고
    • Clinical and endocrine data for goserelin plus second line endocrine therapy for premenopausal advanced breast cancer
    • Forward DP, Cheung KL, Lackson L. Clinical and endocrine data for goserelin plus second line endocrine therapy for premenopausal advanced breast cancer. Br. J. Cancer 90, 590-594 (2004).
    • (2004) Br. J. Cancer , vol.90 , pp. 590-594
    • Forward, D.P.1    Cheung, K.L.2    Lackson, L.3
  • 27
    • 60549097419 scopus 로고    scopus 로고
    • Endocrine therapy plus zoledronic acid in premenopausal breast cancer
    • Gnant M., Mineritsch B, Schippinger W. et al. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N. Engl. J. Med. 360, 679-691 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 679-691
    • Gnant, M.1    Mineritsch, B.2    Schippinger, W..3
  • 28
    • 33746455931 scopus 로고    scopus 로고
    • Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial (18233230)
    • Eastell R, Hannon RA, Cuzick J et al. Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial (18233230). J. Bone Miner. Res. 21, 1215-1223 (2006).
    • (2006) J. Bone Miner. Res. , vol.21 , pp. 1215-1223
    • Eastell, R.1    Hannon, R.A.2    Cuzick, J.3
  • 29
    • 33747058527 scopus 로고    scopus 로고
    • Effect of letrozole versus placebo on bone mineral density in women with primary breast cancer completing 5 or more years of adjuvant tamoxifen: A companion study to NCIC CTG MA.17
    • Perez EA, Josse RG, Pritchard KI et al. Effect of letrozole versus placebo on bone mineral density in women with primary breast cancer completing 5 or more years of adjuvant tamoxifen: A companion study to NCIC CTG MA.17. J. Clin. Oncol. 24, 3629-3635 2006)
    • (2006) J. Clin. Oncol. , vol.24 , pp. 3629-3635
    • Perez, E.A.1    Josse, R.G.2    Pritchard, K.I.3
  • 30
    • 77954580167 scopus 로고    scopus 로고
    • Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36 months results of the ZO-FAST Study
    • Eidtmann H, de Boer R, Bundred N, Llombart-Cussac A et al. Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36 months results of the ZO-FAST Study. Ann. Oncol. 21(11), 2188-2194 (2010).
    • (2010) Ann. Oncol. , vol.21 , Issue.11 , pp. 2188-2194
    • Eidtmann, H.1    De Boer, R.2    Bundred, N.3    Llombart-Cussac, A.4
  • 31
    • 49949115926 scopus 로고    scopus 로고
    • Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage brest cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy
    • Gnant M, Mlineritsch B, Luschin G et al. Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage brest cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy. Lancet Oncol. 9(9), 840-849 (2008).
    • (2008) Lancet Oncol. , vol.9 , Issue.9 , pp. 840-849
    • Gnant, M.1    Mlineritsch, B.2    Luschin, G.3
  • 32
    • 34548537700 scopus 로고    scopus 로고
    • Prevalence of joint symptoms in postmenopausal women taking aromatase inhibitors for early-stage breast cancer
    • Innovative article showing clinical evidence of the risk of AI-related joint symptoms in the adjuvant therapy of early breast cancer
    • Crew KD, Greenlee H, Capodice J et al. Prevalence of joint symptoms in postmenopausal women taking aromatase inhibitors for early-stage breast cancer. J. Clin. Oncol. 25(25), 3877-3883 (2007). Innovative article showing clinical evidence of the risk of AI-related joint symptoms in the adjuvant therapy of early breast cancer.
    • (2007) J. Clin. Oncol. , vol.25 , Issue.25 , pp. 3877-3883
    • Crew, K.D.1    Greenlee, H.2    Capodice, J.3
  • 33
    • 77949720281 scopus 로고    scopus 로고
    • Outcomes of women who were premenopausal at diagnosis of early stage breast cancer in the NCIC CTG MA17 Trial
    • San Antonio, TX, USA, 9-13 December (Abstract 13
    • Goss PE, Ingle JN, Martino S et al. Outcomes of women who were premenopausal at diagnosis of early stage breast cancer in the NCIC CTG MA17 Trial. Presented at: San Antonio Breast Cancer Symposium. San Antonio, TX, USA, 9-13 December 2009 (Abstract 13).
    • (2009) Presented at: San Antonio Breast Cancer Symposium
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 34
    • 0036256991 scopus 로고    scopus 로고
    • Serum 25-hydoxyvitamin D status of adolescents and adults in two seasonal subpopulations from BHANES III
    • Looker AC, Dawson-Hughes B, Calvo MS et al. Serum 25-hydoxyvitamin D status of adolescents and adults in two seasonal subpopulations from BHANES III. Bone 30, 771-777 (2002).
    • (2002) Bone , vol.30 , pp. 771-777
    • Looker, A.C.1    Dawson-Hughes, B.2    Calvo, M.S.3
  • 35
    • 77949887519 scopus 로고    scopus 로고
    • Randomized, blinded, sham-controlled trial of acupuncture for the management of aromatase inhibitor-associated joint symptoms in women with early-stage breast cancer
    • Crew KD, Capodice JL, Greenlee H et al. Randomized, blinded, sham-controlled trial of acupuncture for the management of aromatase inhibitor-associated joint symptoms in women with early-stage breast cancer. J. Clin. Oncol. 28(7), 1154-1160 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.7 , pp. 1154-1160
    • Crew, K.D.1    Capodice, J.L.2    Greenlee, H.3
  • 36
    • 36048965807 scopus 로고    scopus 로고
    • Memory impairments with adjuvant anastrozole versus tamoxifen in women with early-stage breast cancer
    • Bender CM, Sereika SM, Brufsky AM et al. Memory impairments with adjuvant anastrozole versus tamoxifen in women with early-stage breast cancer. Menopause 14(6), 995-998 (2007).
    • (2007) Menopause , vol.14 , Issue.6 , pp. 995-998
    • Bender, C.M.1    Sereika, S.M.2    Brufsky, A.M.3
  • 37
    • 79151479469 scopus 로고    scopus 로고
    • Cognitive function in postmenopausal breast cancer patients one year after completing adjuvant endocrine therapy with letrozole and/or tamoxifen in the BIG 1-98 trial
    • Phillips KA, Aldridge J, Ribi K et al. Cognitive function in postmenopausal breast cancer patients one year after completing adjuvant endocrine therapy with letrozole and/or tamoxifen in the BIG 1-98 trial. Breast Cancer Res Treat. 126(1), 221-226 (2010).
    • (2010) Breast Cancer Res Treat , vol.126 , Issue.1 , pp. 221-226
    • Phillips, K.A.1    Aldridge, J.2    Ribi, K.3
  • 38
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG) Confirmation at 15 years of follow-up in randomized trials of the positive effects on survival of chemotherapy and hormonal therapy for early breast cancer
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials. Lancet 365(9472), 2005). Confirmation at 15 years of follow-up in randomized trials of the positive effects on survival of chemotherapy and hormonal therapy for early breast cancer.
    • Lancet , vol.365 , Issue.9472 , pp. 2005
  • 39
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
    • Howell A, Cuzick J, Baum M et al. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 365(9453), 60-62 (2005).
    • (2005) Lancet , vol.365 , Issue.9453 , pp. 60-62
    • Howell, A.1    Cuzick, J.2    Baum, M.3
  • 40
    • 33947510501 scopus 로고    scopus 로고
    • Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrineresponsive early breast cancer: Update of study BIG 1-98
    • Update confirming the positive results of the BIG 1-98 study published in the New England Journal of Medicine in 2005.
    • Coates AS, Keshaviah A, Thurlimann B et al. Five years of letrozole compared with tamoxifen as initial adjuvant therapy for postmenopausal women with endocrineresponsive early breast cancer: Update of study BIG 1-98. J. Clin. Oncol. 25(5), 486-492 (2007). Update confirming the positive results of the BIG 1-98 study published in the New England Journal of Medicine in 2005.
    • (2007) J. Clin. Oncol. , vol.25 , Issue.5 , pp. 486-492
    • Coates, A.S.1    Keshaviah, A.2    Thurlimann, B.3
  • 41
    • 33846545851 scopus 로고    scopus 로고
    • Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): A randomised controlled trial
    • Coombes RC, Kilburn LS, Snowdon CF et al. Survival and safety of exemestane versus tamoxifen after 2-3 years' tamoxifen treatment (Intergroup Exemestane Study): A randomised controlled trial. Lancet 369(9561), 559-570 (2007).
    • (2007) Lancet , vol.369 , Issue.9561 , pp. 559-570
    • Coombes, R.C.1    Kilburn, L.S.2    Snowdon, C.F.3
  • 43
    • 37449028688 scopus 로고    scopus 로고
    • Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial
    • Forbes JF, Cuzick J, Buzdar A, Howell A, Tobias JS, Baum M. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. Lancet Oncol. 9, 45-53 (2008).
    • (2008) Lancet Oncol. , vol.9 , pp. 45-53
    • Forbes, J.F.1    Cuzick, J.2    Buzdar, A.3    Howell, A.4    Tobias, J.S.5    Baum, M.6
  • 44
    • 34447574894 scopus 로고    scopus 로고
    • Improved overall survival in postmenopausal women with early breast cancer after anastrozole initiated after treatment with tamoxifen compared with continued tamoxifen: The ARNO 95 Study
    • Kaufmann M, Jonat W, Hilfrich J et al. Improved overall survival in postmenopausal women with early breast cancer after anastrozole initiated after treatment with tamoxifen compared with continued tamoxifen: The ARNO 95 Study. J. Clin. Oncol. 1, 25(19), 2664-70 (2007).
    • (2007) J. Clin. Oncol. 1 , vol.25 , Issue.19 , pp. 2664-70
    • Kaufmann, M.1    Jonat, W.2    Hilfrich, J.3
  • 45
    • 33644896808 scopus 로고    scopus 로고
    • Quality of life in the Intergroup Exemestane Study: A randomized trial of exemestane versus continued tamoxifen after 2 to 3 years of tamoxifen in postmenopausal women with primary breast cancer
    • Fallowfield L, Bliss J, Porter L et al. Quality of life in the Intergroup Exemestane Study: A randomized trial of exemestane versus continued tamoxifen after 2 to 3 years of tamoxifen in postmenopausal women with primary breast cancer. J. Clin. Oncol. 24, 910-917 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , pp. 910-917
    • Fallowfield, L.1    Bliss, J.2    Porter, L.3
  • 46
    • 36049032413 scopus 로고    scopus 로고
    • Comparison of menopausal symptoms during the first year of adjuvant therapy with either exemestane or tamoxifen in early breast cancer: Report of a Tamoxifen Exemestane Adjuvant Multicenter trial substudy
    • Jones SE, Cantrell J, Vukelja S et al. Comparison of menopausal symptoms during the first year of adjuvant therapy with either exemestane or tamoxifen in early breast cancer: Report of a Tamoxifen Exemestane Adjuvant Multicenter trial substudy. J. Clin. Oncol. 25(30), 4765-4771 2007)
    • (2007) J. Clin. Oncol. , vol.25 , Issue.30 , pp. 4765-4771
    • Jones, S.E.1    Cantrell, J.2    Vukelja, S.3
  • 47
    • 33746408229 scopus 로고    scopus 로고
    • Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: Long-term safety analysis of the ATAC trial. Arimidex, Tamoxifen, Alone or in Combination Trialists' Group
    • Buzdar A, Howell A, Cuzick J et al. Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: Long-term safety analysis of the ATAC trial. Arimidex, Tamoxifen, Alone or in Combination Trialists' Group. Lancet Oncol. 7(8), 633-643 (2006).
    • (2006) Lancet Oncol. , vol.7 , Issue.8 , pp. 633-643
    • Buzdar, A.1    Howell, A.2    Cuzick, J.3
  • 48
    • 33645292020 scopus 로고    scopus 로고
    • Caution: Vaginal estradiol appears to be contraindicated in postmenopausal women on adjuvant aromatase inhibitors
    • Kendall A, Dowsett M, Folkerd E, Smith I. Caution: Vaginal estradiol appears to be contraindicated in postmenopausal women on adjuvant aromatase inhibitors. Ann. Oncol. 17(4), 584-587 (2006).
    • (2006) Ann. Oncol. , vol.17 , Issue.4 , pp. 584-587
    • Kendall, A.1    Dowsett, M.2    Folkerd, E.3    Smith, I.4
  • 49
    • 0037354228 scopus 로고    scopus 로고
    • A cohort study of topical vaginal estrogen therapy in women previously treated for breast cancer
    • Dew JE, Wren BG, Eden JA. A cohort study of topical vaginal estrogen therapy in women previously treated for breast cancer. Climacteric 6(1), 45-52 (2003).
    • (2003) Climacteric , vol.6 , Issue.1 , pp. 45-52
    • Dew, J.E.1    Wren, B.G.2    Eden, J.A.3
  • 50
    • 72249101980 scopus 로고    scopus 로고
    • Effect of intravaginal dehydroepiandrosterone (prasterone) on libido and sexual dysfunction in postmenopausal women
    • Labrie F, Archer D, Bouchard C et al. Effect of intravaginal dehydroepiandrosterone (prasterone) on libido and sexual dysfunction in postmenopausal women. Menopause 16(5), 923-931 (2009).
    • (2009) Menopause , vol.16 , Issue.5 , pp. 923-931
    • Labrie, F.1    Archer, D.2    Bouchard, C.3
  • 51
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomized trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: An overview of the randomized trials. Lancet 351, 1451-1467 (1998).
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 52
    • 11444251764 scopus 로고    scopus 로고
    • Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer
    • The ATAC Trialists' Group
    • The ATAC Trialists' Group. Results of the ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial after completion of 5 years' adjuvant treatment for breast cancer. Lancet 365, 60-62 (2005).
    • (2005) Lancet , vol.365 , pp. 60-62
  • 53
    • 29544433211 scopus 로고    scopus 로고
    • A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer
    • The Breast International Group (BIG 1-98 Collaborative Group
    • The Breast International Group (BIG 1-98 Collaborative Group. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N. Engl. J. Med. 353, 2747-2757 (2006).
    • (2006) N. Engl. J. Med. , vol.353 , pp. 2747-2757
  • 54
    • 78751647876 scopus 로고    scopus 로고
    • Adjuvant tamoxifen and exemestane in early breast cancer (TEAM): A randomised phase 3 trial
    • 9762
    • Van de Velde CJ, Rea D, Seynaeve C et al. Adjuvant tamoxifen and exemestane in early breast cancer (TEAM): A randomised phase 3 trial. Lancet 22, 377(9762), 321-331 (2011).
    • (2011) Lancet , vol.22 , Issue.377 , pp. 321-331
    • Van De Velde, C.J.1    Rea, D.2    Seynaeve, C.3
  • 55
    • 77949624914 scopus 로고    scopus 로고
    • Long-term endometrial effects in postmenopausal women with early breast cancer participating in the intergroup exemestane study (IES) - A randomised controlled trial of exemestane versus continued tamoxifen after 2-3 years tamoxifen
    • Bertelli G, Hall E, Ireland E et al.. Long-term endometrial effects in postmenopausal women with early breast cancer participating in the intergroup exemestane study (IES) - a randomised controlled trial of exemestane versus continued tamoxifen after 2-3 years tamoxifen. Ann. Oncol. 21(3), 498-505 (2010).
    • (2010) Ann. Oncol. , vol.21 , Issue.3 , pp. 498-505
    • Bertelli, G.1    Hall, E.2    Ireland, E.3
  • 56
    • 23444446523 scopus 로고    scopus 로고
    • Switching of postmenopausal women with endocrine- responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: Combined results of ABCSG trial 8 and ARNO 95 trial
    • Jakesz R, Jonat W, Mittlboeck M. Switching of postmenopausal women with endocrine- responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: Combined results of ABCSG trial 8 and ARNO 95 trial. Lancet 366, 455-462 (2005).
    • (2005) Lancet , vol.366 , pp. 455-462
    • Jakesz, R.1    Jonat, W.2    Mittlboeck, M.3
  • 57
    • 51549106798 scopus 로고    scopus 로고
    • The intergroup exemestane study: A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer [published erratum appears in N
    • Coombes RC, Hall E, Gibson LJ et al. The intergroup exemestane study: A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer [published erratum appears in N. Engl. J. Med. 351, 2461 (2004).]
    • (2004) Engl. J. Med. , vol.351 , pp. 2461
    • Coombes, R.C.1    Hall, E.2    Gibson, L.J.3
  • 58
    • 10744223655 scopus 로고    scopus 로고
    • Innovative clinical approach demonstrating that exemestane therapy after 2-3 years of tamoxifen therapy significantly improves disease-free survival compared with the standard 5 years of tamoxifen treatment.
    • N. Engl. J. Med. 350, 1081-1092 (2004). Innovative clinical approach demonstrating that exemestane therapy after 2-3 years of tamoxifen therapy significantly improves disease-free survival compared with the standard 5 years of tamoxifen treatment.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1081-1092
  • 59
    • 24644519961 scopus 로고    scopus 로고
    • Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: Preliminary results of the Italian tamoxifen anastrozole trial
    • Boccardo F, Rubagotti A, Puntoni M et al. Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: Preliminary results of the Italian tamoxifen anastrozole trial. J. Clin. Oncol. 23, 5138-5147 2005)
    • (2005) J. Clin. Oncol. , vol.23 , pp. 5138-5147
    • Boccardo, F.1    Rubagotti, A.2    Puntoni, M.3
  • 60
    • 24744450378 scopus 로고    scopus 로고
    • Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17
    • Demonstrates that letrozole, after tamoxifen, improves both disease-free and distant disease-free survival but not overall survival, with the exclusion of node-positive patients
    • Goss PE, Ingle JN, Martino S et al. Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: Updated findings from NCIC CTG MA.17. J. Natl Cancer Inst. Cancer Spec. 97, 1262-1271 (2005). Demonstrates that letrozole, after tamoxifen, improves both disease-free and distant disease-free survival but not overall survival, with the exclusion of node-positive patients.
    • (2005) J. Natl Cancer Inst. Cancer Spec. , vol.97 , pp. 1262-1271
    • Goss, P.E.1    Ingle, J.N.2    Martino, S.3
  • 61
    • 23444435619 scopus 로고    scopus 로고
    • Extended adjuvant treatment with anastrozole: Results from the Austrian breast and colorectal cancer study group trial 6a (ABCSG-6a)
    • Abstract 527
    • Jakesz R. Extended adjuvant treatment with anastrozole: Results from the Austrian breast and colorectal cancer study group trial 6a (ABCSG-6a). ASCO annual meeting (2005) (Abstract 527).
    • (2005) ASCO Annual Meeting
    • Jakesz, R.1
  • 62
    • 70249095048 scopus 로고    scopus 로고
    • A question of duration: Do patients with early stage breast cancer need more than five years of adjuvant endocrine therapy?
    • Burdette-Radoux S, Muss HE. A question of duration: Do patients with early stage breast cancer need more than five years of adjuvant endocrine therapy? Clin. Breast Cancer 9(Suppl. 1), S37-S41 (2009).
    • (2009) Clin. Breast Cancer , vol.9 , Issue.SUPPL. 1
    • Burdette-Radoux, S.1    Muss, H.E.2


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