The aging gut microbiota: New perspectives

Ageing Research Reviews

Volumn 10, Issue 4, 2011, Pages 428-429

  Biagi, Elena ^a   Candela, Marco ^a   Franceschi, Claudio ^a   Brigidi, Patrizia ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Aging effect; Gut microbiota; Human Intestinal Tract Chip

Indexed keywords

AGING; BACTEROIDETES; DIETARY INTAKE; GEOGRAPHY; HOUSEHOLD; HUMAN; INTESTINE FLORA; REVIEW; SENESCENCE;

AGED, 80 AND OVER; AGING; ANIMALS; GASTROINTESTINAL TRACT; HUMANS; METAGENOME;

EID: 80052307460     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2011.03.004     Document Type: Review

References (17)

1. Biagi E., Nylund L., Candela M., Bucci L., Ostan R., Nikkila J., Monti D., Satokari R., Franceschi C., Brigidi P., de Vos W.M. Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PLoS ONE 2010, 5. e10667.
2. Capri M., Salvioli S., Monti D., Caruso C., Candore G., Vasto S., Olivieri F., Marchegiani F., Sansoni P., Baggio G., Mari D., Passarino G., De Benedictis G., Franceschi C. Human longevity within an evolutionary perspective: the peculiar paradigm of a post-reproductive genetics. Exp. Gerontol. 2008, 43:53-60.
3. Cellini E., Nacmias B., Olivieri F., Ortenzi L., Tedde A., Bagnoli S., Petruzzi C., Franceschi C., Sorbi S. Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians. Mech. Ageing Dev. 2005, 126:826-828.
4. Claesson M.J., O'Sullivan O., Wang Q., Nikkila J., Marchesi J.R., Smidt H., de Vos W.M., Paul Ross R., O'Toole P.W. Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine. PLoS ONE 2009, 4:e6669.
5. Claesson M.J., Cusack S., O'Sullivan O., Greene-Diniz R., de Weerd H., Flannery E., Marchesi J.R., Falush D., Dinan T., Fitzgerald G., Stanton C., van Sinderen D., O'Connor M., Harnedy N., O'Connor K., Henry C., O'Mahony D., Fitzgerald A.P., Shanahan F., Twomey C., Hill C., Paul Ross R., O'Toole P.W. Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proc. Natl. Acad. Sci. U.S.A. 2010, epub ahead of print.
6. Di Bona D., Vasto S., Capurso C., Christiansen L., Deiana L., Franceschi C., Hurme M., Mocchegiani E., Rea M., Lio D., Candore G., Caruso C. Effect of interleukin-6 polymorphisms on human longevity: a systematic review and meta-analysis. Ageing Res. Rev. 2009, 8:36-42.
7. Franceschi C., Valensin S., Bonafè M., Paolisso G., Yashin A.I., Monti D., De Benedictis G. The network and the remodeling theories of aging: historical background and new perspectives. Exp. Gerontol. 2000, 35:879-896.
8. Guigoz Y., Doré J., Schiffrin J. The inflammatory status of old age can be nurtured from the intestinal environment. Curr. Opin. Clin. Nutr. Metab. Care 2008, 11:13-20.
9. Larbi A., Franceschi C., Mazzatti D., Solana R., Wikby A., Pawelec G. Aging of the immune system as a prognostic factor for human longevity. Physiology (Bethesda) 2008, 23:64-74.
10. Mäkivuokko H., Tiihonen K., Tynkkynen S., Paulin L., Rautonen N. The effect of age and non-steroidal anti-inflammatory drugs on human intestinal microbiota composition. Br. J. Nutr. 2010, 103:227-234.
11. Maslowski K.M., Mackay C.R. Diet, gut microbiota and immune responses. Nat. Immunol. 2011, 12:5-9.
12. Mueller S., Saunier K., Hanisch C., Norin E., Alm L., Midtvedt T., Cresci A., Silvi S., Orpianesi C., Verdenelli M.C., Clavel T., Koebnick C., Zunft H.J.F., Doré J., Blaut M. Differences in fecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl. Environ. Microbiol. 2006, 72:1027-1033.
13. Salvioli S., Olivieri F., Marchegiani F., Cardelli M., Santoro A., Bellavista E., Mishto M., Invidia L., Capri M., Valensin S., Sevini F., Cevenini E., Celani L., Lescai F., Gonos E., Caruso C., Paolisso G., De Benedictis G., Monti D., Franceschi C. Genes, ageing and longevity in humans: problems, advantages and perspectives. Free Radic. Res. 2006, 40:1303-1323.
14. Tiihonen K., Ouwehand A.C., Rautonen N. Human intestinal microbiota and healthy ageing. Ageing Res. Rev. 2010, 9:107-116.
15. Van den Bogert B., de Vos W.M., Zoetendal E.G., Kleerebezem M. Microarray analysis and barcoded pyrosequencing provide consistent microbial profiles depending on the source of human intestinal samples. Appl. Environ. Microbiol. 2011, epub ahead of print.
16. Van Tongeren S.P., Slaets J.P.J., Harmsen H.J.M., Welling G.W. Fecal microbiota composition and frailty. Appl. Environ. Microbiol. 2005, 71:6438-6442.
17. Zwielehner J., Liszt K., Handschur M., Lassl C., Lapin A., Haslberger A.G. Combined PCR-DGGE fingerprinting and quantitative-PCR indicates shifts in fecal population sizes and diversity of Bacteroides, bifidobacteria and Clostridium cluster IV in institutionalized elderly. Exp. Gerontol. 2009, 44:440-446.