Prepulse inhibition of the startle reflex and response to antipsychotic treatments in two outbred mouse strains in comparison to the inbred DBA/2 mouse

Psychopharmacology

Volumn 215, Issue 3, 2011, Pages 441-454

  Flood, Dorothy G ^a   Zuvich, Eva ^a   Marino, Michael J ^a,b   Gasior, MacIej ^a  

^a CEPHALON INC   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Acoustic startle reflex; Antipsychotics; DBA 2 mouse; Glycine transporter 1 inhibitor; Histamine H3 receptor antagonist; Outbred strains; Prepulse inhibition; Schizophrenia; Sensorimotor gating

Indexed keywords

2 CHLORO N [ALPHA (2 PIPERIDINYL)BENZYL] 3 TRIFLUOROMETHYLBENZAMIDE; CLOZAPINE; HALOPERIDOL; THIOPERAMIDE; NEUROLEPTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DBA 2 MOUSE; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG RESPONSE; MALE; MOUSE; NONHUMAN; OUTBRED STRAIN; PREPULSE INHIBITION; PRIORITY JOURNAL; STARTLE REFLEX; STRAIN DIFFERENCE; ANIMAL; BRAIN; C57BL MOUSE; DBA MOUSE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; METABOLISM; PATHOPHYSIOLOGY; SCHIZOPHRENIA; SPECIES DIFFERENCE;

ANIMALS; ANIMALS, OUTBRED STRAINS; ANTIPSYCHOTIC AGENTS; BRAIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; SCHIZOPHRENIA; SPECIES SPECIFICITY; STARTLE REACTION;

EID: 80052304944     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-011-2196-5     Document Type: Article

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