Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4 DCAF1 to suppress oncogenic gene expression

Science Signaling

Volumn 4, Issue 188, 2011, Pages

  Cooper, Jonathan ^a   Li, Wei ^a   You, Liru ^a   Schiavon, Gaia ^a   Pepe Caprio, Angela ^a   Zhou, Lu ^b   Ishii, Ryohei ^c   Giovannini, Marco ^d   Hanemann, C Oliver ^b   Long, Stephen B ^a   Erdjument Bromage, Hediye ^a   Zhou, Pengbo ^c   Tempst, Paul ^a   Giancotti, Filippo G ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b PLYMOUTH UNIVERSITY PENINSULA SCHOOLS OF MEDICINE AND DENTISTRY   (United Kingdom)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d HOUSE EAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EZRIN; MERLIN; MOESIN; MUTANT PROTEIN; P21 ACTIVATED KINASE; PROTEIN CRL4 DCAF1; RADIXIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; UBIQUITIN PROTEIN LIGASE;

BIOACCUMULATION; CANCER CELL CULTURE; CANCER MODEL; CARCINOGENESIS; CELL MEMBRANE; CELL NUCLEUS; CELL PROLIFERATION; CONFERENCE PAPER; ENZYME INACTIVATION; GENE; GENE EXPRESSION; HUMAN; MITOGENESIS; MUTATION; NEURILEMOMA; NF2 GENE; NUCLEAR LOCALIZATION SIGNAL; ONCOGENE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE; ANIMAL; ARTICLE; ENZYMOLOGY; GENE EXPRESSION REGULATION; MOUSE; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; CELL NUCLEUS; GENE EXPRESSION REGULATION; MICE; NEUROFIBROMIN 2; ONCOGENES; PHOSPHORYLATION; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 80052300279     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2002314     Document Type: Conference Paper

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