The d-galacturonic acid catabolic pathway in botrytis cinerea

Fungal Genetics and Biology

Volumn 48, Issue 10, 2011, Pages 990-997

  Zhang, Lisha ^a   Thiewes, Harry ^a   van Kan, Jan A L ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Grey mould; Pathogen; Pectin degradation; Uronic acid catabolism

Indexed keywords

2 KETO 3 DEOXY LEVO GALACTONATE ALDOLASE; GALACTONATE DEHYDRATASE; GALACTURONATE REDUCTASE; GALACTURONIC ACID; PECTIN; UNCLASSIFIED DRUG;

APPLE; ARTICLE; ASPERGILLUS NIDULANS; ASPERGILLUS NIGER; BCGAR1 GENE; BCGAR2 GENE; BCLGD1 GENE; BELL PEPPER; BOTRYTIS CINEREA; CATABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; FUNGAL GENE; FUNGAL GENOME; FUNGAL VIRULENCE; GENE IDENTIFICATION; HYPOCREA JECORINA; NONHUMAN; ORGANISMS BY CARBON SOURCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TOMATO;

ALCOHOL OXIDOREDUCTASES; ALDEHYDE-LYASES; BOTRYTIS; CAPSICUM; CARBOHYDRATE DEHYDROGENASES; DISACCHARIDES; MALUS; METABOLIC NETWORKS AND PATHWAYS; MUTATION; PECTINS; SUGAR ACIDS;

BOTRYOTINIA FUCKELIANA; BOTRYTIS; CAPSICUM; EMERICELLA NIDULANS; ESCHERICHIA COLI; FUNGI; HYPOCREA JECORINA; LYCOPERSICON ESCULENTUM; MALUS X DOMESTICA;

EID: 80052271961     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2011.06.002     Document Type: Article

References (29)

1. Buchanan C.L., Connaris H., Danson M.J., Reeve C.D., Hough D.W. An extremely thermostable aldolase from Sulfolobus solfataricus with specificity for non-phosphorylated substrates. Biochem. J. 1999, 343:563-570.
2. Cabanne C., Doneche B. Purification and characterization of two isozymes of polygalacturonase from Botrytis cinerea: effect of calcium ions on polygalacturonase activity. Microbiol. Res. 2002, 157:183-189.
3. Dewey F.M., Hill M., DeScenzo R. Quantification of Botrytis and laccase in winegrapes. Am. J. Enol. Vitic. 2008, 59:47-54.
4. Dulermo T., Rascle C., Chinnici G., Gout E., Bligny R., Cotton P. Dynamic carbon transfer during pathogenesis of sunflower by the necrotrophic fungus Botrytis cinerea: from plant hexoses to mannitol. New Phytol. 2009, 183:1149-1162.
5. Hilditch S., Berghall S., Kalkkinen N., Penttila M., Richard P. The missing link in the fungal D-galacturonate pathway: identification of the L-threo-3-deoxy-hexulosonate aldolase. J. Biol. Chem. 2007, 282:26195-26201.
6. Hondmann D.H., Busink R., Witteveen C.F., Visser J. Glycerol catabolism in Aspergillus nidulans. J. Gen. Microbiol. 1991, 137:629-636.
7. Kars I., van Kan J.A.L. Extracellular enzymes and metabolites involved in pathogenesis of Botrytis. Botrytis: Biology, Pathology and Control 2004, 99-118. Kluwer Academic Publishers, The Netherlands. Y. Elad, B. Williamson, P. Tudzynski, N. Delen (Eds.).
8. Kars I., Krooshof G.H., Wagemakers L., Joosten R., Benen J.A., van Kan J.A.L. Necrotizing activity of five Botrytis cinerea endopolygalacturonases produced in Pichia pastoris. Plant J. 2005, 43:213-225.
9. Kars I., Wagemakers C.A.M., McCalman M., van Kan J.A.L. Functional analysis of Botrytis cinerea pectin methylesterase genes by PCR-based targeted mutagenesis: Bcpme1 and Bcpme2 are dispensable for virulence of strain B05.10. Mol. Plant Pathol. 2005, 6:641-652.
10. Kravtchenko T.P., Voragen A.G.J., Pilnik W. Analytical comparison of three industrial pectin preparations. Carbohydr. Polym. 1992, 18:17-25.
11. Kuorelahti S., Kalkkinen N., Penttilä M., Londesborough J., Richard P. Identification in the mold Hypocrea jecorina of the first fungal D-galacturonic acid reductase. Biochemistry 2005, 44:11234-11240.
12. Kuorelahti S., Jouhten P., Maaheimo H., Penttilä M., Richard P. L-galactonate dehydratase is part of the fungal path for D-galacturonic acid catabolism. Mol. Microbiol. 2006, 61:1060-1068.
13. Liepins J., Kuorelahti S., Penttila M., Richard P. Enzymes for the NADPH-dependent reduction of dihydroxyacetone and D-glyceraldehyde and L-glyceraldehyde in the mould Hypocrea jecorina. FEBS J. 2006, 273:4229-4235.
14. Martens-Uzunova E.S., Schaap P.J. An evolutionary conserved D-galacturonic acid metabolic pathway operates across filamentous fungi capable of pectin degradation. Fungal Genet. Biol. 2008, 45:1449-1457.
15. Meyer U., Dewey F. Efficacy of different immunogens for raising monoclonal antibodies to Botrytis cinerea. Mycol. Res. 2000, 104:979-987.
16. Mojzita D., Wiebve M., Hilditch S., Boer H., Penttilä M., Richard P. Metabolic engineering of fungal strains for conversion of D-galacturonate to meso-galactarate. Appl. Environ. Microbiol. 2010, 76:169-175.
17. Rha E., Park H.J., Kim M.O., Chung Y.R., Lee C.W., Kim J.W. Expression of exo-polygalacturonases in Botrytis cinerea. FEMS Microbiol. Lett. 2001, 201:105-109.
18. Richard P., Hilditch S. D-galacturonic acid catabolism in microorganisms and its biotechnological relevance. Appl. Microbiol. Biotechnol. 2009, 82:597-604.
19. Sealy-Lewis H.M., Fairhurst V. An NADP(+)-dependent glycerol dehydrogenase in Aspergillus nidulans is inducible by D-galacturonate. Curr. Genet. 1992, 22:293-296.
20. ten Have A., Mulder W., Visser J., van Kan J.A.L. The endopolygalacturonase gene Bcpg1 is required for full virulence of Botrytis cinerea. Mol. Plant-Microbe Interact. 1998, 11:1009-1016.
21. ten Have A., Tenberge K.B., Benen J.A.E., Tudzynski P., Visser J., van Kan J.A.L. The contribution of the cell wall degrading enzymes to pathogenesis of fungal plant pathogens. The Mycota XI, Agricultural Applications 2002, 341-358. Springer-Verlag, Berlin. F. Kempken (Ed.).
22. Uitzetter J.H., Bos C.J., Visser J. Characterization of Aspergillus nidulans mutants in carbon metabolism isolated after D-galacturonate enrichment. J. Gen. Microbiol. 1986, 132:1167-1172.
23. van Kan J.A.L. Licensed to kill: the lifestyle of a necrotrophic plant pathogen. Trends Plant Sci. 2006, 11:247-253.
24. van Kan J.A.L., van 't Klooster J.W., Dees D.C.T., Wagemakers C.A.M., van der Vlugt-Bergmans C.J.B. Cutinase A of Botrytis cinerea is expressed, but not essential, during penetration of gerbera and tomato. Mol. Plant-Microbe Interact. 1997, 10:30-38.
25. Visser J., Van Rooijen R., Dijkema C., Swart K., Sealy-Lewis H.M. Glycerol uptake mutants of the hyphal fungus Aspergillus nidulans. J. Gen. Microbiol. 1988, 134:655-659.
26. Wiebe M.G., Mojzita D., Hilditch S., Ruohone L., Penttilä M. Bioconversion of D-galacturonate to keto-deoxy-L-galactonate (3-deoxy-L-threo-hex-2-ulosonate) using filamentous fungi. BMC Biotechnol. 2010, 10:63.
27. Williamson B., Tudzynski B., Tudzynski P., van Kan J.A.L. Botrytis cinerea: the cause of grey mould disease. Mol. Plant Pathol. 2007, 8:561-580.
28. Wubben J.P., Mulder W., ten Have A., van Kan J.A.L., Visser J. Cloning and partial characterization of endopolygalacturonase genes from Botrytis cinerea. Appl. Environ. Microbiol. 1999, 65:1596-1602.
29. Wubben J.P., ten Have A., van Kan J.A.L., Visser J. Regulation of endopolygalacturonase gene expression in Botrytis cinerea by galacturonic acid, ambient pH and carbon catabolite repression. Curr. Genet. 2000, 37:152-157.