Using X-chromosomal markers in relationship testing: Calculation of likelihood ratios taking both linkage and linkage disequilibrium into account

Forensic Science International: Genetics

Volumn 5, Issue 5, 2011, Pages 506-511

  Tillmar, Andreas O ^a   Egeland, Thore ^b,c   Lindblom, Bertil ^a   Holmlund, Gunilla ^a   Mostad, Petter ^d  

^a National Board of Forensic Medicine   (Sweden)

^b UNIVERSITY OF OSLO   (Norway)

^c OSLO METROPOLITAN UNIVERSITY   (Norway)

^d CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

Haplotype frequency estimation; Linkage; Linkage disequilibrium; Simulation; X chromosome

Indexed keywords

ARTICLE; CASE REPORT; CHROMOSOME MARKER; CONTROLLED STUDY; DATA ANALYSIS; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC MODEL; HAPLOTYPE; HUMAN; MALE; MEDICAL RECORD; PRIORITY JOURNAL; SIMULATION; X CHROMOSOME;

CHROMOSOMES, HUMAN, X; FAMILY; FEMALE; GENETIC LINKAGE; GENETIC MARKERS; HAPLOTYPES; HUMANS; LIKELIHOOD FUNCTIONS; MALE; PEDIGREE;

EID: 80052265276     PISSN: 18724973     EISSN: 18780326     Source Type: Journal    
DOI: 10.1016/j.fsigen.2010.11.004     Document Type: Article

References (16)

1. M. Tracey Short tandem repeat-based identification of individuals and parents Croat. Med. J. 42 2001 233 238 (Pubitemid 32606982)
2. R. Szibor X-chromosomal markers: past, present and future Forensic Sci. Int. Genet. 1 2007 93 99 (Pubitemid 46760407)
3. R. Szibor, M. Krawczak, S. Hering, J. Edelmann, E. Kuhlisch, and D. Krause Use of X-linked markers for forensic purposes Int. J. Legal Med. 117 2003 67 74 (Pubitemid 36717446)
4. D.W. Gjertson, C.H. Brenner, M.P. Baur, A. Carracedo, F. Guidet, J.A. Luque, R. Lessig, W.R. Mayr, V.L. Pascali, M. Prinz, P.M. Schneider, and N. Morling ISFG: recommendations on biostatistics in paternity testing Forensic Sci. Int. Genet. 1 2007 223 231 (Pubitemid 47365769)
5. J.S. Buckleton, C.M. Triggs, and S.J. Walsh Forensic DNA Evidence Interpretation 2005 CRC Press Boca Raton
6. J. Ott Analysis of Human Genetic Linkage 3rd ed. 1999 The Johns Hopkins University Press Baltimore
7. R.C. Elston, and J. Stewart A general model for the genetic analysis of pedigree data Hum. Hered. 21 1971 523 542
8. E.S. Lander, and P. Green Construction of multilocus genetic linkage maps in humans Proc. Natl. Acad. Sci. U.S.A. 84 1987 2363 2367 (Pubitemid 17075870)
9. A. Kurbasic, and O. Hössjer A general method for linkage disequilibrium correction for multipoint linkage and association Genet. Epidemiol. 32 2008 647 657
10. D. Becker, H. Rodig, C. Augustin, J. Edelmann, F. Götz, S. Hering, R. Szibor, and W. Brabetz Population genetic evaluation of eight X-chromosomal short tandem repeat loci using Mentype Argus X-8 PCR amplification kit Forensic Sci. Int. Genet. 2 2008 69 74 (Pubitemid 350091442)
11. A.O. Tillmar, P. Mostad, T. Egeland, B. Lindblom, G. Holmlund, and K. Montelius Analysis of linkage and linkage disequilibrium for eight X-STR markers Forensic Sci. Int. Genet. 3 2008 37 41
12. M. Krawczak Kinship testing with X-chromosomal markers: mathematical and statistical issues Forensic Sci. Int. Genet. 1 2007 111 114 (Pubitemid 46760397)
13. G.R. Abecasis, S.S. Cherny, W.O. Cookson, and L.R. Cardon MERLIN-rapid analysis of dense genetic maps using sparse gene flow trees Nat. Genet. 30 2002 97 101
14. Ø. Skare, N. Sheehan, and T. Egeland Identification of distant family relationships Bioinformatics 25 2009 2376 2382
15. G.R. Abecasis, and J.E. Wigginton Handling marker-marker linkage disequilibrium: pedigree analysis with clustered markers Am. J. Hum. Genet. 77 2005 754 767 (Pubitemid 41513278)
16. R. Szibor, S. Hering, E. Kuhlisch, I. Plate, S. Demberger, M. Krawczak, and J. Edelmann Haplotyping of STR cluster DXS6801-DXS6809-DXS6789 on Xq21 provides a powerful tool for kinship testing Int. J. Legal Med. 119 2005 363 369 (Pubitemid 41586731)