Estimated pKa values for specific amino acid residues in daptomycin

Journal of Pharmaceutical Sciences

Volumn 100, Issue 10, 2011, Pages 4225-4233

  Qiu, Jiang ^a   Yu, Liping ^b   Kirsch, Lee E ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Analytical biochemistry; Daptomycin; Fluorescence spectroscopy; Ionization constant; NMR spectroscopy; Peptides; Physicochemical properties

Indexed keywords

4 METHYLGLUTAMIC ACID; ALIPHATIC AMINE; AROMATIC AMINE; ASPARTIC ACID; DAPTOMYCIN; SODIUM CHLORIDE; AMINO ACID; ANTIINFECTIVE AGENT;

ARTICLE; FLUORESCENCE SPECTROSCOPY; IONIZATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHOTON CORRELATION SPECTROSCOPY; POTENTIOMETRIC TITRATION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROSCOPY; AMINO ACID SEQUENCE; CHEMISTRY; MEDICINAL CHEMISTRY; PH; PHARMACEUTICS; PROCEDURES; PROTEIN CONFORMATION; SPECTROFLUOROMETRY; ULTRAVIOLET SPECTROPHOTOMETRY;

AMINO ACID SEQUENCE; AMINO ACIDS; ANTI-BACTERIAL AGENTS; CHEMISTRY, PHARMACEUTICAL; DAPTOMYCIN; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET; TECHNOLOGY, PHARMACEUTICAL;

EID: 80052261676     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22608     Document Type: Article

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