The neuroanatomical substrate of lexical-semantic decline in MCI APOE ε4 carriers and noncarriers

Alzheimer Disease and Associated Disorders

Volumn 25, Issue 3, 2011, Pages 230-241

  Venneri, Annalena ^a,b,c   McGeown, William J ^a   Biundo, Roberta ^a   Mion, Marco ^b   Nichelli, Paolo ^b   Shanks, Michael F ^a  

^a UNIVERSITY OF HULL   (United Kingdom)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c IRCCS SAN CAMILLO HOSPITAL   (Italy)

Author keywords

age of acquisition; Alzheimer disease; endophenotype; lexical; magnetic resonance imaging

Indexed keywords

APOLIPOPROTEIN E4;

AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN SIZE; CEREBELLUM; CINGULATE GYRUS; CONTROLLED STUDY; ENDOPHENOTYPE; FEMALE; FRONTAL LOBE; GENOTYPE PHENOTYPE CORRELATION; GRAY MATTER; HETEROZYGOTE; HIPPOCAMPUS; HUMAN; LANGUAGE DISABILITY; LANGUAGE TEST; LEFT HEMISPHERE; MAJOR CLINICAL STUDY; MALE; MILD COGNITIVE IMPAIRMENT; NEOCORTEX; NEUROANATOMY; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PARAHIPPOCAMPAL GYRUS; PARIETAL LOBE; PRECUNEUS; PRIORITY JOURNAL; RIGHT HEMISPHERE; SEMANTICS; TEMPORAL LOBE; UNCUS;

AGED; APOLIPOPROTEIN E4; BRAIN; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MILD COGNITIVE IMPAIRMENT; NEUROPSYCHOLOGICAL TESTS; SEMANTICS;

EID: 80052260004     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/WAD.0b013e318206f88c     Document Type: Article

References (72)

1. Petersen RC, Smith GE, Waring SC, et al. Mild cognitive impairment: Clinical characterization and outcome. Arch Neurol. 1999;56:303-308. (Pubitemid 29120227)
2. Petersen RC, Ivnik RJ, Boeve BF, et al. Outcome of clinical subtypes of mild cognitive impairment. Neurology. 2004;62: A29S.
3. Dubois B, Feldman HH, Jacova C, et al. Research criteria for the diagnosis of Alzheimer's disease: Revising the NINCDSADRDA criteria. Lancet Neurol. 2007;6:734-746. (Pubitemid 47058377)
4. Forbes-McKay KE, Ellis AW, Shanks MF, et al. The age of acquisition of words produced in a semantic fluency task can reliably differentiate normal from pathological age related cognitive decline. Neuropsychologia. 2005;43:1625-1632. (Pubitemid 40961683)
5. Venneri A, Forbes-Mckay KE, Shanks MF. Impoverishment of spontaneous language and the prediction of Alzheimer's disease. Brain. 2005;128:E27.
6. Venneri A, McGeown WJ, Hietanen HM, et al. The anatomical bases of semantic retrieval deficits in early Alzheimer's disease. Neuropsychologia. 2008;46:497-510. (Pubitemid 351186552)
7. McGeownWJ, Shanks MF, Forbes-McKay KE, et al. Patterns of brain activity during a semantic task differentiate normal aging from early Alzheimer's disease. Psychiatry Res Neuroimaging. 2009;173:218-227.
8. Lambon Ralph MA, Graham KS, Ellis AW, et al. Naming in semantic dementia-what matters? Neuropsychologia. 1998;36: 775-784.
9. Biundo R, Gardini S, Concari L, et al. Genetic influences on the decline of semantic skills in Mild Cognitive Impairment. J Int Neuropsychol Society. 2010. In press.
10. Arango-Lasprilla JC, Cuetos F, Valencia C, et al. Cognitive changes in the preclinical phase of familial Alzheimer's disease. J Clin Exp Neuropsychol. 2007;29:892-900. (Pubitemid 350145777)
11. Reiman EM, Chen KW, Alexander GE, et al. Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia. Proc Natl Acad Sci U S A. 2004;101: 284-289. (Pubitemid 38084242)
12. Smith CD, Andersen AH, Kryscio RJ, et al. Altered brain activation in cognitively intact individuals at high risk for Alzheimer's disease. Neurology. 1999;53:1391-1396. (Pubitemid 29491926)
13. Smith CD, Andersen AH, Kryscio RJ, et al. Women at risk for AD show increased parietal activation during a fluency task. Neurology. 2002;58:1197-1202. (Pubitemid 34411863)
14. Seidenberg M, Guidotti L, Nielson KA, et al. Semantic memory activation in individuals at risk for developing Alzheimer disease. Neurology. 2009;73:612-620.
15. Raber J. The impact of APOE on cognition and behavior. Alzheimer Dement: J Alzheimer Assoc. 2009;5:168.
16. Jack CR Jr, Petersen RC, Xu YC, et al. Hippocampal atrophy and apolipoprotein E genotype are independently associated with Alzheimer's disease. Ann Neurol. 1998;43: 303-310. (Pubitemid 28113592)
17. Reiman EM, Uecker A, Caselli RJ, et al. Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease. Ann Neurol. 1998;44:288-291. (Pubitemid 28374124)
18. Plassman BL, Welsh-Bohmer KA, Bigler ED, et al. Apolipoprotein E epsilon 4 allele and hippocampal volume in twins with normal cognition. Neurology. 1997;48:985-989.
19. Burggren AC, Zeineh MM, Ekstrom AD, et al. Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers. Neuroimage. 2008; 41:1177-1183.
20. Mueller SG, Schuff N, Raptentsetsang S, et al. Selective effect of Apo e4 on CA3 and dentate in normal aging and Alzheimer's disease using high resolution MRI at 4 T. Neuroimage. 2008;42:42-48.
21. Petersen RC, Doody R, Kurz A, et al. Current concepts in mild cognitive impairment. Arch Neurol. 2001;58:1985-1992. (Pubitemid 33143977)
22. Petersen RC. Mild cognitive impairment as a diagnostic entity. J Intern Med. 2004;256:183-194. (Pubitemid 39222988)
23. McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer's disease: Report of the NINCDSADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944.
24. Brun A, Englund B, Gustafson L, et al. Clinical and Neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry. 1994;57:416-418. (Pubitemid 24118135)
25. Roman GC, Tatemichi TK, Erkinjuntti T, et al. Vascular dementia: Diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology. 1993;43: 250-260. (Pubitemid 23060253)
26. McKeith IG, Galasko D, Kosaka K, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology. 1996;47:1113-1124. (Pubitemid 26374873)
27. Lawton MP, Brody EM. Assessment of older people: Selfmaintaining and instrumental activities of daily living. Gerontologist. 1969;9:179-186.
28. Wechsler D. Wechsler Adult Intelligence Scale. 3rd ed. San Antonio: The Psychological Corporation; 1997.
29. Wechsler D. Wechsler Memory Scale III. San Antonio: The Psychological Corporation, Harcourt Brace & Co.; 1997.
30. Measso G, Cavarzeran F, Zappala G, et al. The mini-mental state examination: Normative study of an Italian random sample. Develop Neuropsychol. 1993;9:77-85.
31. De Renzi E, Faglioni P. Normative data and screening power of a shortened version of the Token Test. Cortex. 1978;14: 41-49. (Pubitemid 8327451)
32. Novelli G, Papagno C, Capitani E, et al. Tre test clinici di produzione lessicale. Taratura su soggetti normali. Arch Psicol Neurol Psichiatr. 1986;47:477-506.
33. Novelli G, Papagno C, Capitani E, et al. Tre test clinici di memoria verbale a lungo termine. Taratura su soggetti normali. Arch Psicol Neurol Psichiatr. 1986;47:278-296.
34. Spinnler H, Tognoni G. Standardizzazione e taratura italiana di test neuropsicologici. Ital J Neurol Sci. 1987;6:1-120.
35. Caffarra P, Vezzadini G, Dieci F, et al. Rey-Osterrieth complex figure: Normative values in an Italian population sample. Neurol Sci. 2002;22:443-447. (Pubitemid 34436807)
36. Basso A, Capitani E, Laiacona M. Raven's coloured progressive matrices and brain damage: Normative values on 305 adult normal controls. Funct Neurol. 1987;II:189-194. (Pubitemid 18028273)
37. Caffarra P, Vezzadini G, Dieci F, et al. Una versione abbreviata del test di Stroop. Dati normativi nella popolazione italiana. Nuova Riv Neurol. 2002;12:111-115. (Pubitemid 35332213)
38. Morrison CM, Chappell TD, Ellis AW. Age of acquisition norms for a large set of object names and their relation to adult estimates and other variables. Qly J Exp Psychol. 1997;50A: 528-559.
39. Larochelle S, Richard S, Soulieres I. What some effects might not be: The time to verify membership in "Well defined" categories. Qly J Exp Psychol. 2000;53:929-961.
40. Ashburner J, Friston KJ. Unified segmentation. Neuroimage. 2005;26:839-851. (Pubitemid 40825026)
41. Ashburner J. A fast diffeomorphic image registration algorithm. Neuroimage. 2007;38:95-113. (Pubitemid 47440133)
42. Ashburner J, Friston KJ. Computing average shaped tissue probability templates. Neuroimage. 2009;45:333-341.
43. Evans AC, Collins DL, Mills SR, et al. 3D statistical neuroanatomical models from 305 MRI volumes. Proceedings IEEE-Nuclear Science Symposium and Mdeical Imaging Conference. San Francisco, CA, USA: IEEE, 1993:1813-1817.
44. Davatzikos C, Genc A, Xu D et al. Voxel-based morphometry using the RAVENS maps: Methods and validation using simulated longitudinal atrophy. Neuroimage. 2001;14:1361-1369. (Pubitemid 33124184)
45. Schlosser R, Hutchinson M, Joseffer S, et al. Functional magnetic resonance imaging of human brain activity in a verbal fluency task. J Neurol Neurosurg Psychiatry. 1998;64: 492-498. (Pubitemid 28195951)
46. Gourovitch ML, Kirkby BS, Goldberg TE, et al. A comparison of rCBF patterns during letter and semantic fluency. Neuropsychology. 2000;14:353-360.
47. Hubrich-Ungureanu P, Kaemmerer N, Henn FA, et al. Lateralized organization of the cerebellum in a silent verbal fluency task: A functional magnetic resonance imaging study in healthy volunteers. Neurosci Lett. 2002;319:91-94. (Pubitemid 34127938)
48. Ravnkilde B, Videbech P, Rosenberg R, et al. Putative tests of frontal lobe function: A PET-study of brain activation during Stroop's Test and verbal fluency. J Clin Exp Neuropsychol. 2002;24:534-547. (Pubitemid 34775557)
49. Richter S, Gerwig M, Aslan B, et al. Cognitive functions in patients with MR-defined chronic focal cerebellar lesions. J Neurol. 2007;254:1193-1203. (Pubitemid 350112346)
50. Ito M. Control of mental activities by internal models in the cerebellum. Nat Rev Neurosci. 2008;9:304-313. (Pubitemid 351430830)
51. Lehtovirta M, Laaksoa MP, Frisoni GB, et al. How does the apolipoprotein E genotype modulate the brain in aging and in Alzheimer's disease? A review of neuroimaging studies. Neurobiol Aging. 2000;21:293-300. (Pubitemid 30387088)
52. Filippini N, Rao A, Wetten S, et al. Anatomically-distinct genetic associations of APOE epsilon4 allele load with regional cortical atrophy in Alzheimer's disease. Neuroimage. 2009;44: 724-728.
53. Farlow MR, He Y, Tekin S, et al. Impact of APOE in mild cognitive impairment. Neurology. 2004;63:1898-1901. (Pubitemid 39532387)
54. Morra JH, Tu Z, Apostolova LG, et al. Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. Neuroimage. 2009;45:S3-S15.
55. van de Pol LA, Van Der Flier WM, Korf ESC, et al. Baseline predictors of rates of hippocampal atrophy in mild cognitive impairment. Neurology. 2007;69:1491-1497. (Pubitemid 47537855)
56. Fleisher A, Grundman M, Jack CR Jr, et al. Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment. Arch Neurol. 2005;62:953-957. (Pubitemid 40973457)
57. Hamalainen A, Grau-Olivares M, Tervo S, et al. Apolipoprotein E epsilon 4 allele is associated with increased atrophy in progressive mild cognitive impairment: A voxelbased morphometric study. Neurodegenerat Dis. 2008;5: 186-189. (Pubitemid 351347846)
58. Pennanen C, Testa C, Boccardi M, et al. The effect of apolipoprotein polymorphism on brain in mild cognitive impairment: A voxel-based morphometric study. Dement Geriatr Cogn Disord. 2006;22:60-66.
59. Bassett SS, Yousem DM, Cristinzio C, et al. Familial risk for Alzheimer's disease alters fMRI activation patterns. Brain. 2006;129:1229-1239.
60. Petersen RC, Smith GE, Ivnik RJ, et al. Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals. JAMA. 1995;273: 1274-1278.
61. Noppeney U, Patterson K, Tyler LK, et al. Temporal lobe lesions and semantic impairment: A comparison of herpes simplex virus encephalitis and semantic dementia. Brain. 2007; 130:1138-1147. (Pubitemid 47355584)
62. Williams GB, Nestor PJ, Hodges JR. Neural correlates of semantic and behavioural deficits in frontotemporal dementia. Neuroimage. 2005;24:1042-1051. (Pubitemid 40164506)
63. Desgranges B, Matuszewski V, Piolino P, et al. Anatomical and functional alterations in semantic dementia: A voxel-based MRI and PET study. Neurobiol Aging. 2007;28:1904-1913. (Pubitemid 47539693)
64. Birn RM, Kenworthy L, Case L, et al. Neural systems supporting lexical search guided by letter and semantic category cues: A self-paced overt response fMRI study of verbal fluency. Neuroimage. 2010;49:1099-1107.
65. Gaillard WD, Sachs BC, Whitnah JR, et al. Developmental aspects of language processing: FMRI of verbal fluency in children and adults. Hum Brain Mapp. 2003;18:176-185. (Pubitemid 36331573)
66. Mesulam MM. Neuroplasticity failure in Alzheimer's disease: Bridging the gap between plaques and tangles. Neuron. 1999; 24:521-529.
67. Mesulam MM. A plasticity-based theory of the pathogenesis of Alzheimer's disease. Ann N Y Acad Sci. 2000;924:42-52. (Pubitemid 32050182)
68. Lyketsos CG, Lopez O, Jones B, et al. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: Results from the cardiovascular health study. JAMA. 2002;288:1475-1483.
69. Palmer K, Berger AK, Monastero R, et al. Predictors of progression from mild cognitive impairment to Alzheimer disease. Neurology. 2007;68:1596-1602. (Pubitemid 46717984)
70. Bruen PD, McGeown WJ, Shanks MF, et al. Neuroanatomical correlates of neuropsychiatric symptoms in Alzheimer's disease. Brain. 2008;131:2455-2463.
71. Larner AJ. The cerebellum in Alzheimer's disease. Dement Geriatr Cogn Disord. 1997;8:203-209. (Pubitemid 27243704)
72. Verghese J, Robbins M, Holtzer R, et al. Gait dysfunction in mild cognitive impairment syndromes. J Am Geriatr Soc. 2008; 56:1244-1251.