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Volumn 71, Issue 17, 2011, Pages 5827-5837

Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CD40 ANTIGEN; CD40 LIGAND; CD86 ANTIGEN; COXSACKIE VIRUS AND ADENOVIRUS RECEPTOR; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DENDRITIC CELL VACCINE; GAMMA INTERFERON; GLYCOPROTEIN GP 100; GLYCOPROTEIN P 15095; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TYROSINASE RELATED PROTEIN 2; TYROSINASE RELATED PROTEIN 2[180-188]; UNCLASSIFIED DRUG;

EID: 80052251198     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-0804     Document Type: Article
Times cited : (31)

References (49)
  • 1
    • 65249088470 scopus 로고    scopus 로고
    • Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients
    • Verdijk P, Aarntzen EH, Lesterhuis WJ, Boullart AC, Kok E, van Rossum MM, et al. Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clin Cancer Res 2009;15:2531-40.
    • (2009) Clin Cancer Res , vol.15 , pp. 2531-2540
    • Verdijk, P.1    Aarntzen, E.H.2    Lesterhuis, W.J.3    Boullart, A.C.4    Kok, E.5    Van Rossum, M.M.6
  • 4
    • 14844295742 scopus 로고    scopus 로고
    • Migration of dendritic cell based cancer vaccines: In vivo veritas?
    • DOI 10.1016/j.coi.2005.01.004, Lymphocyte Development - Tumor Immunology
    • Adema GJ, de Vries IJ, Punt CJ, Figdor CG. Migration of dendritic cell based cancer vaccines: in vivo veritas? Curr Opin Immunol 2005;17:170-4. (Pubitemid 40343104)
    • (2005) Current Opinion in Immunology , vol.17 , Issue.2 , pp. 170-174
    • Adema, G.J.1    De Vries, I.J.M.2    Punt, C.J.A.3    Figdor, C.G.4
  • 5
    • 34748886192 scopus 로고    scopus 로고
    • Dendritic-cell immunotherapy: From ex vivo loading to in vivo targeting
    • DOI 10.1038/nri2173, PII NRI2173
    • Tacken PJ, de Vries IJ, Torensma R, Figdor CG. Dendritic-cell immunotherapy: from ex vivo loading to in vivo targeting. Nat Rev Immunol 2007;7:790-802. (Pubitemid 47480309)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.10 , pp. 790-802
    • Tacken, P.J.1    De Vries, I.J.M.2    Torensma, R.3    Figdor, C.G.4
  • 6
    • 51349141264 scopus 로고    scopus 로고
    • Dendritic cells in vivo:A key target for a new vaccine science
    • Steinman RM. Dendritic cells in vivo: a key target for a new vaccine science. Immunity 2008;29:319-24.
    • (2008) Immunity , vol.29 , pp. 319-324
    • Steinman, R.M.1
  • 7
    • 23044463870 scopus 로고    scopus 로고
    • Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice
    • DOI 10.1158/0008-5472.CAN-05-0938
    • Mahnke K, Qian Y, Fondel S, Brueck J, Becker C, Enk AH. Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice. Cancer Res 2005;65:7007-12. (Pubitemid 41060741)
    • (2005) Cancer Research , vol.65 , Issue.15 , pp. 7007-7012
    • Mahnke, K.1    Qian, Y.2    Fondel, S.3    Brueck, J.4    Becker, C.5    Enk, A.H.6
  • 8
    • 58149355293 scopus 로고    scopus 로고
    • Inhibition of melanoma growth by targeting of antigen to dendritic cells via an anti-DEC-205 single-chain fragment variable molecule
    • Johnson TS, Mahnke K, Storn V, Schonfeld K, Ring S, Nettelbeck DM, et al. Inhibition of melanoma growth by targeting of antigen to dendritic cells via an anti-DEC-205 single-chain fragment variable molecule. Clin Cancer Res 2008;14:8169-77.
    • (2008) Clin Cancer Res , vol.14 , pp. 8169-8177
    • Johnson, T.S.1    Mahnke, K.2    Storn, V.3    Schonfeld, K.4    Ring, S.5    Nettelbeck, D.M.6
  • 9
    • 68049111686 scopus 로고    scopus 로고
    • Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice
    • Wei H, Wang S, Zhang D, Hou S, Qian W, Li B, et al. Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice. Clin Cancer Res 2009;15:4612-21.
    • (2009) Clin Cancer Res , vol.15 , pp. 4612-4621
    • Wei, H.1    Wang, S.2    Zhang, D.3    Hou, S.4    Qian, W.5    Li, B.6
  • 10
    • 33947704632 scopus 로고    scopus 로고
    • Specific targeting of whole lymphoma cells to dendritic cells ex vivo provides a potent antitumor vaccine
    • Adam C, Mysliwietz J, Mocikat R. Specific targeting of whole lymphoma cells to dendritic cells ex vivo provides a potent antitumor vaccine. J Transl Med 2007;5:16.
    • (2007) J Transl Med , vol.5 , pp. 16
    • Adam, C.1    Mysliwietz, J.2    Mocikat, R.3
  • 11
    • 34249111217 scopus 로고    scopus 로고
    • Lentiviral vectors for cancer immunotherapy: Transforming infectious particles into therapeutics
    • DOI 10.1038/sj.gt.3302947, PII 3302947
    • Breckpot K, Aerts JL, Thielemans K. Lentiviral vectors for cancer immunotherapy: transforming infectious particles into therapeutics. Gene Ther 2007;14:847-62. (Pubitemid 46780068)
    • (2007) Gene Therapy , vol.14 , Issue.11 , pp. 847-862
    • Breckpot, K.1    Aerts, J.L.2    Thielemans, K.3
  • 12
    • 33748778266 scopus 로고    scopus 로고
    • Liposomal vaccines-targeting the delivery of antigen
    • DOI 10.1016/j.ymeth.2006.05.027, PII S1046202306001605
    • Altin JG, Parish CR. Liposomal vaccines-targeting the delivery of antigen. Methods 2006;40:39-52. (Pubitemid 44415497)
    • (2006) Methods , vol.40 , Issue.1 , pp. 39-52
    • Altin, J.G.1    Parish, C.R.2
  • 13
    • 34748840807 scopus 로고    scopus 로고
    • In vivo targeting of antigens to human dendritic cells through DC-SIGN elicits stimulatory immune responses and inhibits tumor growth in grafted mouse models
    • DOI 10.1097/CJI.0b013e318135472c, PII 0000237120071000000005
    • Kretz-Rommel A, Qin F, Dakappagari N, Torensma R, Faas S, Wu D, et al. In vivo targeting of antigens to human dendritic cells through DC-SIGN elicits stimulatory immune responses and inhibits tumor growth in grafted mouse models. J Immunother 2007;30:715-26. (Pubitemid 47480755)
    • (2007) Journal of Immunotherapy , vol.30 , Issue.7 , pp. 715-726
    • Kretz-Rommel, A.1    Qin, F.2    Dakappagari, N.3    Torensma, R.4    Faas, S.5    Wu, D.6    Bowdish, K.S.7
  • 17
    • 0034306991 scopus 로고    scopus 로고
    • Adenoviral vectors targeted to CD40 enhance the efficacy of dendritic cell-based vaccination against human papillomavirus 16-induced tumor cells in a murine model
    • Tillman BW, Hayes TL, DeGruijl TD, Douglas JT, Curiel DT. Adenoviral vectors targeted to CD40 enhance the efficacy of dendritic cell-based vaccination against human papillomavirus 16-induced tumor cells in a murine model. Cancer Res 2000;60:5456-63.
    • (2000) Cancer Res , vol.60 , pp. 5456-5463
    • Tillman, B.W.1    Hayes, T.L.2    DeGruijl, T.D.3    Douglas, J.T.4    Curiel, D.T.5
  • 18
    • 0036842008 scopus 로고    scopus 로고
    • MHC class I and class II presentation of tumor antigen in retrovirally and adenovirally transduced dendritic cells
    • DOI 10.1038/sj.cgt.7700509
    • Sloan JM, Kershaw MH, Touloukian CE, Lapointe R, Robbins PF, Restifo NP, et al. MHC class I and class II presentation of tumor antigen in retrovirally and adenovirally transduced dendritic cells. Cancer Gene Ther 2002;9:946-50. (Pubitemid 35278567)
    • (2002) Cancer Gene Therapy , vol.9 , Issue.11 , pp. 946-950
    • Sloan, J.M.1    Kershaw, M.H.2    Touloukian, C.E.3    Lapointe, R.4    Robbins, P.F.5    Restifo, N.P.6    Hwu, P.7
  • 20
    • 23344437656 scopus 로고    scopus 로고
    • Adenoviral vectors for mucosal vaccination against infectious diseases
    • DOI 10.1089/vim.2005.18.283
    • Santosuosso M, McCormick S, Xing Z. Adenoviral vectors for mucosal vaccination against infectious diseases. Viral Immunol 2005;18:283-91. (Pubitemid 41106007)
    • (2005) Viral Immunology , vol.18 , Issue.2 , pp. 283-291
    • Santosuosso, M.1    McCormick, S.2    Xing, Z.3
  • 21
    • 68949215573 scopus 로고    scopus 로고
    • Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 5
    • Abe S, Okuda K, Ura T, Kondo A, Yoshida A, Yoshizaki S, et al. Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 5. J Gene Med 2009;11:570-9.
    • (2009) J Gene Med , vol.11 , pp. 570-579
    • Abe, S.1    Okuda, K.2    Ura, T.3    Kondo, A.4    Yoshida, A.5    Yoshizaki, S.6
  • 22
    • 27144482675 scopus 로고    scopus 로고
    • Genetic targeting strategies for adenovirus
    • DOI 10.1021/mp050045c
    • Noureddini SC, Curiel DT. Genetic targeting strategies for adenovirus. Mol Pharm 2005;2:341-7. (Pubitemid 41503674)
    • (2005) Molecular Pharmaceutics , vol.2 , Issue.5 , pp. 341-347
    • Noureddini, S.C.1    Curiel, D.T.2
  • 25
    • 0034893581 scopus 로고    scopus 로고
    • + T cell-dependent mechanism
    • DOI 10.1038/sj.gt.3301521
    • Steitz J, Bruck J, Knop J, Tuting T. Adenovirus-transduced dendritic cells stimulate cellular immunity to melanoma via a CD4(+) T cell-dependent mechanism. Gene Ther 2001;8:1255-63. (Pubitemid 32780814)
    • (2001) Gene Therapy , vol.8 , Issue.16 , pp. 1255-1263
    • Steitz, J.1    Bruck, J.2    Knop, J.3    Tuting, T.4
  • 26
    • 14844341146 scopus 로고
    • Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression
    • Kawakami Y, Eliyahu S, Jennings C, Sakaguchi K, Kang X, Southwood S, et al. Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression. J Immunol 1995;154:3961-8.
    • (1995) J Immunol , vol.154 , pp. 3961-3968
    • Kawakami, Y.1    Eliyahu, S.2    Jennings, C.3    Sakaguchi, K.4    Kang, X.5    Southwood, S.6
  • 29
    • 0036812719 scopus 로고    scopus 로고
    • Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes
    • DOI 10.1034/j.1600-065X.2002.18816.x
    • Melief CJ, Van Der Burg SH, Toes RE, Ossendorp F, Offringa R. Effective therapeutic anticancer vaccines based on precision guiding of cytolytic T lymphocytes. Immunol Rev 2002;188:177-82. (Pubitemid 35398875)
    • (2002) Immunological Reviews , vol.188 , pp. 177-182
    • Melief, C.J.M.1    Van Der, B.S.H.2    Toes, R.E.M.3    Ossendorp, F.4    Offringa, R.5
  • 32
    • 0037322502 scopus 로고    scopus 로고
    • + T cells: Implications for an efficient vaccination strategy
    • DOI 10.1038/sj.gt.3301880
    • Tuettenberg A, Jonuleit H, Tuting T, Bruck J, Knop J, Enk AH. Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: implications for an efficient vaccination strategy. Gene Ther 2003;10:243-50. (Pubitemid 36204413)
    • (2003) Gene Therapy , vol.10 , Issue.3 , pp. 243-250
    • Tuettenberg, A.1    Jonuleit, H.2    Tuting, T.3    Bruck, J.4    Knop, J.5    Enk, A.H.6
  • 33
    • 32844455349 scopus 로고    scopus 로고
    • Comparison of recombinant adenovirus and synthetic peptide for DC-based melanoma vaccination
    • DOI 10.1038/sj.cgt.7700894, PII 7700894
    • Steitz J, Tormo D, Schweichel D, Tuting T. Comparison of recombinant adenovirus and synthetic peptide for DC-based melanoma vaccination. Cancer Gene Ther 2006;13:318-25. (Pubitemid 43255769)
    • (2006) Cancer Gene Therapy , vol.13 , Issue.3 , pp. 318-325
    • Steitz, J.1    Tormo, D.2    Schweichel, D.3    Tuting, T.4
  • 34
    • 79951813688 scopus 로고    scopus 로고
    • Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine
    • Hangalapura BN, Oosterhoff D, Gupta T, de Groot J, Wijnands PG, van Beusechem VW, et al. Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine. Vaccine 2011;29:2313-21.
    • (2011) Vaccine , vol.29 , pp. 2313-2321
    • Hangalapura, B.N.1    Oosterhoff, D.2    Gupta, T.3    De Groot, J.4    Wijnands, P.G.5    Van Beusechem, V.W.6
  • 37
    • 0037246197 scopus 로고    scopus 로고
    • Simultaneous detection of EGFP and cell surface markers by fluorescence microscopy in lymphoid tissues
    • Kusser KL, Randall TD. Simultaneous detection of EGFP and cell surface markers by fluorescence microscopy in lymphoid tissues. J Histochem Cytochem 2003;51:5-14. (Pubitemid 36133482)
    • (2003) Journal of Histochemistry and Cytochemistry , vol.51 , Issue.1 , pp. 5-14
    • Kusser, K.L.1    Randall, T.D.2
  • 38
    • 0016413580 scopus 로고
    • Biological behavior of malignant melanoma cells correlated to their survival in vivo
    • Fidler IJ. Biological behavior of malignant melanoma cells correlated to their survival in vivo. Cancer Res 1975;35:218-24.
    • (1975) Cancer Res , vol.35 , pp. 218-224
    • Fidler, I.J.1
  • 41
    • 0031041233 scopus 로고    scopus 로고
    • Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma
    • BloomM.B., Perry-Lalley D.,Robbins P.F., Li Y., el-Gamil M., Rosenberg S.A., et al. Identification of tyrosinase-related protein 2 as a tumor rejection antigen for the B16 melanoma. J Exp Med 1997;185: 453-9.
    • (1997) J Exp Med , vol.185 , pp. 453-459
    • Bloom, M.B.1    Perry-Lalley, D.2    Robbins, P.F.3    Li, Y.4    El-Gamil, M.5    Rosenberg, S.A.6
  • 42
    • 0033375998 scopus 로고    scopus 로고
    • Enhanced immune response to the melanoma antigen gp100 using recombinant adenovirus-transduced dendritic cells
    • Wan Y, Emtage P, Zhu Q, Foley R, Pilon A, Roberts B, et al. Enhanced immune response to the melanoma antigen gp100 using recombinant adenovirus-transduced dendritic cells. Cell Immunol 1999;198:131-8.
    • (1999) Cell Immunol , vol.198 , pp. 131-138
    • Wan, Y.1    Emtage, P.2    Zhu, Q.3    Foley, R.4    Pilon, A.5    Roberts, B.6
  • 43
    • 67650105908 scopus 로고    scopus 로고
    • Dendritic cells:A critical player in cancer therapy?
    • Palucka AK, Ueno H, Fay J, Banchereau J. Dendritic cells: a critical player in cancer therapy? J Immunother 2008;31:793-805.
    • (2008) J Immunother , vol.31 , pp. 793-805
    • Palucka, A.K.1    Ueno, H.2    Fay, J.3    Banchereau, J.4
  • 44
    • 78650153340 scopus 로고    scopus 로고
    • CD40- Targeted recombinant adenovirus significantly enhances the efficacy of DC and B cell-based anti-tumor vaccines
    • Kim YS, Kim YJ, Lee JM, Han SH, Ko HJ, Park HJ, et al. CD40- targeted recombinant adenovirus significantly enhances the efficacy of DC and B cell-based anti-tumor vaccines. Hum Gene Ther 2010;21:1697-706.
    • (2010) Hum Gene Ther , vol.21 , pp. 1697-1706
    • Kim, Y.S.1    Kim, Y.J.2    Lee, J.M.3    Han, S.H.4    Ko, H.J.5    Park, H.J.6
  • 45
    • 77952237095 scopus 로고    scopus 로고
    • Targeting of antigens to skin dendritic cells:Possibilities to enhance vaccine efficacy
    • Romani N, Thurnher M, Idoyaga J, Steinman RM, Flacher V. Targeting of antigens to skin dendritic cells: possibilities to enhance vaccine efficacy. Immunol Cell Biol 2010;88:424-30.
    • (2010) Immunol Cell Biol , vol.88 , pp. 424-430
    • Romani, N.1    Thurnher, M.2    Idoyaga, J.3    Steinman, R.M.4    Flacher, V.5
  • 47
    • 77955176713 scopus 로고    scopus 로고
    • Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus
    • Hangalapura BN, Oosterhoff D, Aggarwal S, Wijnands PG, van de Ven R, Santegoets SJ, et al. Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus. J Immunother 2010;33:706-15.
    • (2010) J Immunother , vol.33 , pp. 706-715
    • Hangalapura, B.N.1    Oosterhoff, D.2    Aggarwal, S.3    Wijnands, P.G.4    Van De Ven, R.5    Santegoets, S.J.6
  • 48
    • 34548606400 scopus 로고    scopus 로고
    • Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses
    • Lore K, Adams WC, Havenga MJ, Precopio ML, Holterman L, Goudsmit J, et al. Myeloid and plasmacytoid dendritic cells are susceptible to recombinant adenovirus vectors and stimulate polyfunctional memory T cell responses. J Immunol 2007;179:1721-9.
    • (2007) J Immunol , vol.179 , pp. 1721-1729
    • Lore, K.1    Adams, W.C.2    Havenga, M.J.3    Precopio, M.L.4    Holterman, L.5    Goudsmit, J.6
  • 49
    • 0037119944 scopus 로고    scopus 로고
    • Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake
    • Meier O, Boucke K, Hammer SV, Keller S, Stidwill RP, Hemmi S, et al. Adenovirus triggers macropinocytosis and endosomal leakage together with its clathrin-mediated uptake. J Cell Biol 2002;158:1119-31.
    • (2002) J Cell Biol , vol.158 , pp. 1119-1131
    • Meier, O.1    Boucke, K.2    Hammer, S.V.3    Keller, S.4    Stidwill, R.P.5    Hemmi, S.6


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