Motion sickness: A cholinomimetic agent hypothesis

Journal of Vestibular Research: Equilibrium and Orientation

Volumn 21, Issue 4, 2011, Pages 209-217

  Sheehan, Scott E ^a,b   Oman, Charles M ^b   Duda, Kevin R ^b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

autonomic; Etiology; ganglionic; mecamylamine; neural mismatch; nicotine; sensory conflict

Indexed keywords

CATECHOLAMINE; CHOLINERGIC RECEPTOR STIMULATING AGENT; NICOTINIC RECEPTOR;

ANIMAL; ARTICLE; AUTONOMIC GANGLION; BIOLOGICAL MODEL; DRUG EFFECT; HUMAN; MOTION SICKNESS; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION;

ANIMALS; CATECHOLAMINES; CHOLINERGIC AGENTS; GANGLIA, AUTONOMIC; HUMANS; MODELS, NEUROLOGICAL; MOTION SICKNESS; RECEPTORS, NICOTINIC;

EID: 80052247343     PISSN: 09574271     EISSN: None     Source Type: Journal    
DOI: 10.3233/VES-2011-0417     Document Type: Article

References (52)

1. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology, Circulation 93 (1996), 1043-1065.
2. I. Bacher, B. Wu, D.R. Shytle and T.P. George, Mecamylamine - a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders, Expert Opin Pharmacother 10 (2009), 2709-2721.
3. N.L. Benowitz, Drug therapy. Pharmacologic aspects of cigarette smoking and nicotine addition, N Engl J Med 319 (1988), 1318-1330. (Pubitemid 19003394)
4. M. Bernstein and R.R. Sonnenschein, Effects of autonomic ganglionic blocking drugs on cutaneous axone reflexes, J Appl Physiol 7 (1954), 279-282.
5. A.L. Bianchi, Mechanisms and control of emesis : a satellite symposium of the European Neuroscience Association: proceedings of an international meeting held in Marseille (France), 4-7 September 1992: "New Vistas on Mechanisms and Control of Emesis" = Mécanismes et contrôle du vomissement, J. Libbey Eurotext; Editions INSERM, Montrouge, France Paris, France, 1992.
6. O.L. Bock and C.M. Oman, Dynamics of subjective discomfort in motion sickness as measured with a magnitude estimation method, Aviat Space Environ Med 53 (1982), 773-777. (Pubitemid 12017893)
7. T.M. Brody, Human pharmacology: molecular to clinical, Mosby, St. Louis, 1994.
8. L.J.Casarett, J.Doull and C.D.Klaassen, Casarett and Doull"s toxicology: the basic science of poisons, McGraw-Hill, New York, 2008.
9. G.H. Crampton, Motion and space sickness, CRC Press, Boca Raton, Fla., 1990.
10. C.J. Davis, G.V. Lake-Bakaar and D.G. Grahame-Smith, Janssen Pharmaceutical Ltd.Medical Dept. and Janssen Pharmaceutica, Nausea and vomiting: mechanisms and treatment, Springer-Verlag, Berlin; New York, 1986.
11. J.E. Fowlkes, R.S. Kennedy, L.J. Hettinger and D.L. Harm, Changes in the dark focus of accommodation associated with simulator sickness, Aviat Space Environ Med 64 (1993), 612-618. (Pubitemid 23198712)
12. J. Golding et al., The effects of smoking nicotine tobacco versus smoking deprivation onmotion sickness, in: Aerospace Medical Association Meeting, Boston, USA, 2008.
13. S.L. Grainger and S.E. Smith, Dose-response relationships of intravenous hyoscine butylbromide and atropine sulphate on heart rate in healthy volunteers, Br J Clin Pharmacol 16 (1983), 623-626. (Pubitemid 14208197)
14. A. Graybiel, Structural elements in the concept of motion sickness, Aerosp Med 40 (1969), 351-367.
15. A.C. Guyton and J.E. Hall, Textbook of Medical Physiology, Elsevier Saunders, Philadelphia, 2006.
16. J. Herrstedt and P. Dombernowsky, Anti-emetic therapy in cancer chemotherapy: current status, Basic Clin Pharmacol Toxicol 101 (2007), 143-150. (Pubitemid 47256390)
17. N. Himi, T. Koga, E. Nakamura, M. Kobashi, M. Yamane and K. Tsujioka, Differences in autonomic responses between subjectswith andwithout nausea whilewatching an irregularly oscillating video, Auton Neurosci 116 (2004), 46-53. (Pubitemid 39535373)
18. P.J. Hornby, Central neurocircuitry associated with emesis, Am J Med 111 Suppl 8A (2001), 106S-112S. (Pubitemid 34032001)
19. M. Igarashi, S. Chae, S. MacDonald, T. Himi and N. Takeda, Autonomic indexes during the vestibular-visual conflict exposure: a squirrel monkey study, Auris Nasus Larynx 17 (1990), 69-76. (Pubitemid 20302584)
20. M. Igarashi, K. Kobayashi, W.B. Kulecz and T. Himi, Change in susceptibility to vestibular-visual conflict sickness in monkeys by repeated exposure, Acta Otolaryngol 102 (1986), 432-437. (Pubitemid 17173166)
21. D.S. Janowsky, S.C. Risch, M. Ziegler, B. Kennedy and L. Huey, A cholinomimetic model of motion sickness and space adaptation syndrome, Aviat Space Environ Med 55 (1984), 692-696. (Pubitemid 14038657)
22. D. Jezova, I. Skultetyova, D.I. Tokarev, P. Bakos and M. Vigas, Vasopressin and oxytocin in stress, Ann N Y Acad Sci 771 (1995), 192-203. (Pubitemid 26077407)
23. M.J. Joyner and N.M. Dietz, Sympathetic vasodilation in human muscle, Acta Physiol Scand 177 (2003), 329-336. (Pubitemid 36337635)
24. K.L.Koch, R.M. Stern,M.W.Vasey, J.F. Seaton, L.M.Demers and T.S. Harrison, Neuroendocrine and gastric myoelectrical responses to illusory self-motion in humans, Am J Physiol 258 (1990), E304-E310. (Pubitemid 20094645)
25. R.L. Kohl, Autonomic function and plasma catecholamines following stressful sensory stimuli, Aviat Space Environ Med 64 (1993), 921-927. (Pubitemid 23289427)
26. R.L. Kohl and J.L. Homick, Motion sickness: a modulatory role for the central cholinergic nervous system, Neurosci Biobehav Rev 7 (1983), 73-85. (Pubitemid 13154482)
27. I.M. Lang, S.K. Sarna and R. Shaker, Gastrointestinal motor and myoelectric correlates of motion sickness, Am J Physiol 277 (1999), G642-G652. (Pubitemid 29458238)
28. D.H. Malin, J.R. Lake, C.K. Schopen, J.W. Kirk, E.E. Sailer, B.A. Lawless, T.P. Upchurch, M. Shenoi and N. Rajan, Nicotine abstinence syndrome precipitated by central but not peripheral hexamethonium, Pharmacol Biochem Behav 58 (1997), 695-699. (Pubitemid 27438126)
29. B.R. Martin, E.S.Onaivi and T.J. Martin,What is the nature of mecamylamine"s antagonism of the central effects of nicotine? Biochemical Pharmacology 38 (1989), 3391-3397. (Pubitemid 19250188)
30. R.D. Miller, Miller"s anesthesia, Elsevier/Churchill Livingstone, New York, 2005.
31. K.E. Money, Motion sickness, Physiol Rev 50 (1970), 1-39.
32. K.E. Money and B.S. Cheung, Another function of the inner ear: facilitation of the emetic response to poisons, Aviat Space Environ Med 54 (1983), 208-211. (Pubitemid 13091112)
33. K.E. Money and J. Friedberg, The Role of the Semicircular Canals in Causation ofMotion Sickness and Nystagmus in the Dog, Can J Physiol Pharmacol 42 (1964), 793-801.
34. T.J. Mullen, R.D. Berger, C.M. Oman and R.J. Cohen, Human heart rate variability relation is unchanged during motion sickness, J Vestib Res 8 (1998), 95-105. (Pubitemid 28078590)
35. E.R. Muth, Motion and space sickness: intestinal and autonomic correlates, Auton Neurosci 129 (2006), 58-66. (Pubitemid 44470860)
36. C.M. Oman, Motion sickness: a synthesis and evaluation of the sensory conflict theory, Can J Physiol Pharmacol 68 (1990), 294-303. (Pubitemid 20107633)
37. R.L. Papke, P.R. Sanberg and R.D. Shytle, Analysis of mecamylamine stereoisomers on human nicotinic receptor subtypes, J Pharmacol Exp Ther 297 (2001), 646-656. (Pubitemid 32377996)
38. D.M. Parker and W.E. Wilsoncroft, Intensity of motion sickness symptoms as a function of apparent autonomic balance, J Gen Psychol 98 (1978), 253-257.
39. J.T. Reason, Motion sickness adaptation: a neural mismatch model, J R Soc Med 71 (1978), 819-829. (Pubitemid 9047761)
40. B.J. Sadock, V.A. Sadock, P. Ruiz and H.I. Kaplan, Kaplan & Sadock"s comprehensive textbook of psychiatry, Wolters Kluwer Health/Lippincott Williams & Wilkins, Philadelphia, 2009.
41. A.M. Scott, J.E. Kellow, G.M. Eckersley, J.M. Nolan and M.P. Jones, Cigarette smoking and nicotine delay postprandial mouth-cecum transit time, Dig Dis Sci 37 (1992), 1544-1547.
42. A.B. Spinks, J. Wasiak, E.V. Villanueva and V. Bernath, Scopolamine (hyoscine) for preventing and treating motion sickness, Cochrane Database Syst Rev (2007), CD002851.
43. R.M. Stern, K.L. Koch, H.W. Leibowitz, I.M. Lindblad, C.L. Shupert and W.R. Stewart, Tachygastria and motion sickness, Aviat Space Environ Med 56 (1985), 1074-1077. (Pubitemid 16214693)
44. M. Uchino, K. Ishii, M. Kuwahara, S. Ebukuro and H. Tsubone, Role of autonomic nervous system for development and suppression ofmotion sickness in Suncusmurinus, AutonNeurosci 94 (2001), 46-51. (Pubitemid 33152716)
45. M. Wada, T. Arai, T. Takagaki and T. Nakagawa, Axon reflex mechanism in sweat responses to nicotine, acetylcholine and sodium chloride, J Appl Physiol 4 (1952), 745-752.
46. T.Weiser and S. Just, Hyoscine butylbromide potently blocks human nicotinic acetylcholine receptors in SH-SY5Y cells, Neurosci Lett 450 (2009), 258-261.
47. M.A. Wenger, Studies of autonomic balance: a summary, Psychophysiology 2 (1966), 173-186.
48. C.R.Wilpizeski, L.D. Lowry, R.A.Miller, B.D. Smith, Jr. and W. Goldman, Adaptation and habituation of motion-induced vomiting in squirrel monkeys, Aviat Space Environ Med 58 (1987), A22-A28.
49. J.E.Wolf and H.I.Maibach, Palmar eccrine sweating-the role of adrenergic and cholinergic mediators, Br J Dermatol 91 (1974), 439-446.
50. B.J. Yates and A.D. Miller, Vestibular Autonomic Regulation, CRC Press, Boca Raton, 1996.
51. B.J. Yates, A.D. Miller and J.B. Lucot, Physiological basis and pharmacology of motion sickness: an update, Brain Res Bull 47 (1998), 395-406. (Pubitemid 29095346)
52. V.C. Zingler, K. Denecke, K. Jahn, L. vonMeyer, S. Krafczyk, M. Krams, R. Elfont, T. Brandt, M. Strupp and S. Glasauer, The effect of nicotine on perceptual, ocular motor, postural, and vegetative functions at rest and in motion, J Neurol 254 (2007), 1689-1697.