-
1
-
-
80052244513
-
-
(Package insert) BP
-
Sorafenib, (Package insert) BP, 2009.
-
(2009)
Sorafenib
-
-
-
2
-
-
52949128348
-
Evolving Strategies for the Management of Hand-Foot Skin Reaction Associated with the Multitargeted Kinase Inhibitors Sorafenib and Sunitinib
-
Lacouture ME, Wu S, Robert C, et al. Evolving Strategies for the Management of Hand-Foot Skin Reaction Associated with the Multitargeted Kinase Inhibitors Sorafenib and Sunitinib. Oncologist 2008; 13(9): 1001-11.
-
(2008)
Oncologist
, vol.13
, Issue.9
, pp. 1001-1011
-
-
Lacouture, M.E.1
Wu, S.2
Robert, C.3
-
3
-
-
38349102230
-
Risk of hand-foot skin reaction with sorafenib: A systematic review and meta-analysis
-
Chu D, Lacouture ME, Fillos T, Wu S. Risk of hand-foot skin reaction with sorafenib: a systematic review and meta-analysis. Acta Oncol 2008; 47(2): 176-186.
-
(2008)
Acta Oncol
, vol.47
, Issue.2
, pp. 176-186
-
-
Chu, D.1
Lacouture, M.E.2
Fillos, T.3
Wu, S.4
-
4
-
-
65249140606
-
Risk of hand-foot skin reaction with the multitargeted kinase inhibitor sunitinib in patients with renal cell and non-renal cell carcinoma: A meta-analysis
-
Chu D, Lacouture ME, Weiner E, Wu S. Risk of hand-foot skin reaction with the multitargeted kinase inhibitor sunitinib in patients with renal cell and non-renal cell carcinoma: a meta-analysis. Clin Genitourin Cancer 2009; 7(1): 11-19.
-
(2009)
Clin Genitourin Cancer
, vol.7
, Issue.1
, pp. 11-19
-
-
Chu, D.1
Lacouture, M.E.2
Weiner, E.3
Wu, S.4
-
5
-
-
77953757715
-
Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma
-
Schmidinger M, Bellmunt J. Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma. Cancer Treat Rev 2010; 36(5): 416-424.
-
(2010)
Cancer Treat Rev
, vol.36
, Issue.5
, pp. 416-424
-
-
Schmidinger, M.1
Bellmunt, J.2
-
6
-
-
67449164582
-
Phase I trial of pazopanib in patients with advanced cancer
-
Hurwitz HI, Dowlati A, Saini S, et al. Phase I trial of pazopanib in patients with advanced cancer. Clin Cancer Res 2009; 15(12): 4220-4227.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.12
, pp. 4220-4227
-
-
Hurwitz, H.I.1
Dowlati, A.2
Saini, S.3
-
7
-
-
33644586050
-
Reversible posterior leukoencephalopathy syndrome and bevacizumab
-
2006; 354(9): 980-982; discussion -2
-
Glusker P, Recht L, Lane B. Reversible posterior leukoencephalopathy syndrome and bevacizumab. N Engl J Med 2006; 354(9): 980-982; discussion -2.
-
N Engl J Med
-
-
Glusker, P.1
Recht, L.2
Lane, B.3
-
8
-
-
34548169627
-
Reversible posterior leukoencephalopathy syndrome induced by sunitinib
-
Martin G, Bellido L, Cruz JJ. Reversible posterior leukoencephalopathy syndrome induced by sunitinib. J Clin Oncol 2007; 25(23): 3559.
-
(2007)
J Clin Oncol
, vol.25
, Issue.23
, pp. 3559
-
-
Martin, G.1
Bellido, L.2
Cruz, J.J.3
-
9
-
-
33644586050
-
Reversible posterior leukoencephalopa-thy syndrome and bevacizumab
-
discussion -2
-
Ozcan C, Wong SJ, Hari P. Reversible posterior leukoencephalopa-thy syndrome and bevacizumab. N Engl J Med 2006; 354(9): 980-982; discussion -2.
-
(2006)
N Engl J Med
, vol.354
, Issue.9
, pp. 980-982
-
-
Ozcan, C.1
Wong, S.J.2
Hari, P.3
-
10
-
-
12444304260
-
Angiogenic growth factors and hypertension
-
Sane DC, Anton L, Brosnihan KB. Angiogenic growth factors and hypertension. Angiogenesis 2004; 7(3): 193-201.
-
(2004)
Angiogenesis
, vol.7
, Issue.3
, pp. 193-201
-
-
Sane, D.C.1
Anton, L.2
Brosnihan, K.B.3
-
11
-
-
34447635695
-
Angiogenesis inhibitor therapies: Focus on kidney toxicity and hypertension
-
Izzedine H, Rixe O, Billemont B, Baumelou A, Deray G. Angiogenesis inhibitor therapies: focus on kidney toxicity and hypertension. Am J Kidney Dis 2007; 50(2): 203-218.
-
(2007)
Am J Kidney Dis
, vol.50
, Issue.2
, pp. 203-218
-
-
Izzedine, H.1
Rixe, O.2
Billemont, B.3
Baumelou, A.4
Deray, G.5
-
12
-
-
3242660994
-
Inhaled nitric oxide attenuates pulmonary hypertension and improves lung growth in infant rats after neonatal treatment with a VEGF receptor inhibitor
-
Tang JR, Markham NE, Lin YJ, et al. Inhaled nitric oxide attenuates pulmonary hypertension and improves lung growth in infant rats after neonatal treatment with a VEGF receptor inhibitor. Am J Physiol Lung Cell Mol Physiol 2004; 287(2): L344-L351.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
, Issue.2
-
-
Tang, J.R.1
Markham, N.E.2
Lin, Y.J.3
-
13
-
-
33846638744
-
Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis
-
Zhu X, Wu S, Dahut WL, Parikh CR. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: systematic review and meta-analysis. Am J Kidney Dis 2007; 49(2): 186-193.
-
(2007)
Am J Kidney Dis
, vol.49
, Issue.2
, pp. 186-193
-
-
Zhu, X.1
Wu, S.2
Dahut, W.L.3
Parikh, C.R.4
-
14
-
-
77957231200
-
Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels
-
Kappers MH, van Esch JH, Sluiter W, Sleijfer S, Danser AH, van den Meiracker AH. Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels. Hypertension 2010; 56(4): 675-681.
-
(2010)
Hypertension
, vol.56
, Issue.4
, pp. 675-681
-
-
Kappers, M.H.1
van Esch, J.H.2
Sluiter, W.3
Sleijfer, S.4
Danser, A.H.5
van den, M.A.H.6
-
15
-
-
78649537524
-
Biomarkers to predict the clinical efficacy of bevacizumab in cancer
-
Jubb AM, Harris AL. Biomarkers to predict the clinical efficacy of bevacizumab in cancer. Lancet Oncol 2010; 11(12): 1172-1183.
-
(2010)
Lancet Oncol
, vol.11
, Issue.12
, pp. 1172-1183
-
-
Jubb, A.M.1
Harris, A.L.2
-
16
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003; 349(5): 427-434.
-
(2003)
N Engl J Med
, vol.349
, Issue.5
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
17
-
-
27944456516
-
Managing patients treated with bevacizumab combination therapy
-
Gordon MS, Cunningham D. Managing patients treated with bevacizumab combination therapy. Oncology 2005; 69 (Suppl 3): 25-33.
-
(2005)
Oncology
, vol.69
, Issue.3
, pp. 25-33
-
-
Gordon, M.S.1
Cunningham, D.2
-
18
-
-
37349080670
-
Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
-
Escudier B, Pluzanska A, Koralewski P, et al. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007; 370(9605): 2103-2111.
-
(2007)
Lancet
, vol.370
, Issue.9605
, pp. 2103-2111
-
-
Escudier, B.1
Pluzanska, A.2
Koralewski, P.3
-
19
-
-
56749161699
-
Bevacizumab plus inter-feron alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206
-
Rini BI, Halabi S, Rosenberg JE, et al. Bevacizumab plus inter-feron alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206. J Clin Oncol 2008; 26(33): 5422-5428.
-
(2008)
J Clin Oncol
, vol.26
, Issue.33
, pp. 5422-5428
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
-
20
-
-
79951762998
-
High-grade proteinuria associated with bevacizumab in patients with renal cell cancer and non-renal cell cancer
-
[abstract]. Abstract e16089
-
Kim CY, Chu D, Baer L, Wu S. High-grade proteinuria associated with bevacizumab in patients with renal cell cancer and non-renal cell cancer [abstract]. J Clin Oncol 2009; 27(15_Suppl): Abstract e16089.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15
-
-
Kim, C.Y.1
Chu, D.2
Baer, L.3
Wu, S.4
-
21
-
-
80052234567
-
Association between acute severe renal toxicity (ASRT) and survival in patients (pts)with metastatic renal cell carcinoma (mRCC) receiving sunitinib
-
[abstract]
-
Billemont B, Thibault F, Ropert S, et al. Association between acute severe renal toxicity (ASRT) and survival in patients (pts)with metastatic renal cell carcinoma (mRCC) receiving sunitinib. GU Cancer Symp [abstract] 2009.
-
(2009)
GU Cancer Symp
-
-
Billemont, B.1
Thibault, F.2
Ropert, S.3
-
22
-
-
34250365240
-
Mechanisms of adverse effects of anti-VEGF therapy for cancer
-
Kamba T, McDonald DM. Mechanisms of adverse effects of anti-VEGF therapy for cancer. Br J Cancer 2007; 96(12): 1788-1795.
-
(2007)
Br J Cancer
, vol.96
, Issue.12
, pp. 1788-1795
-
-
Kamba, T.1
McDonald, D.M.2
-
23
-
-
77951269420
-
Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis of randomized controlled trials
-
Ranpura V, Hapani S, Chuang J, Wu S. Risk of cardiac ischemia and arterial thromboembolic events with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis of randomized controlled trials. Acta Oncol 2010; 49(3): 287-297.
-
(2010)
Acta Oncol
, vol.49
, Issue.3
, pp. 287-297
-
-
Ranpura, V.1
Hapani, S.2
Chuang, J.3
Wu, S.4
-
24
-
-
77952310126
-
Risk of arterial thromboembolic events with sunitinib and sorafenib: A systematic review and meta-analysis of clinical trials
-
Choueiri TK, Schutz FA, Je Y, Rosenberg JE, Bellmunt J. Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. J Clin Oncol 2010; 28(13): 2280-2285.
-
(2010)
J Clin Oncol
, vol.28
, Issue.13
, pp. 2280-2285
-
-
Choueiri, T.K.1
Schutz, F.A.2
Je, Y.3
Rosenberg, J.E.4
Bellmunt, J.5
-
25
-
-
34548141828
-
Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab
-
Scappaticci FA, Skillings JR, Holden SN, et al. Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab. J Natl Cancer Inst 2007; 99(16): 1232-1239.
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.16
, pp. 1232-1239
-
-
Scappaticci, F.A.1
Skillings, J.R.2
Holden, S.N.3
-
26
-
-
33744954585
-
Sunitinib in patients with metastatic renal cell carcinoma
-
Motzer RJ, Rini BI, Bukowski RM, et al. Sunitinib in patients with metastatic renal cell carcinoma. JAMA 2006; 295(21): 2516-2524.
-
(2006)
JAMA
, vol.295
, Issue.21
, pp. 2516-2524
-
-
Motzer, R.J.1
Rini, B.I.2
Bukowski, R.M.3
-
27
-
-
80052239151
-
-
(package insert) Pfizer Pharmaceuticals N
-
Sutent, (package insert) Pfizer Pharmaceuticals N. 2010.
-
(2010)
Sutent
-
-
-
28
-
-
33846148701
-
Sorafenib in advanced clear-cell renal-cell carcinoma
-
Escudier B, Stadler WM, et al Eisen T,. Sorafenib in advanced clear-cell renal-cell carcinoma. N Engl J Med 2007; 356(2): 125-134.
-
(2007)
N Engl J Med
, vol.356
, Issue.2
, pp. 125-134
-
-
Escudier, B.1
Stadler, W.M.2
Eisen, T.3
-
29
-
-
55949123335
-
Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma
-
Schmidinger M, Zielinski CC, Vogl UM, et al. Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma. J Clin Oncol 2008; 26(32): 5204-5212.
-
(2008)
J Clin Oncol
, vol.26
, Issue.32
, pp. 5204-5212
-
-
Schmidinger, M.1
Zielinski, C.C.2
Vogl, U.M.3
-
30
-
-
77952318310
-
Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
-
Rini BI, Halabi S, Rosenberg JE, et al. Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. J Clin Oncol 2010; 28(13): 2137-2143.
-
(2010)
J Clin Oncol
, vol.28
, Issue.13
, pp. 2137-2143
-
-
Rini, B.I.1
Halabi, S.2
Rosenberg, J.E.3
-
31
-
-
50849094516
-
Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate
-
Telli ML, Witteles RM, Fisher GA, Srinivas S. Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate. Ann Oncol 2008; 19(9): 1613-1618.
-
(2008)
Ann Oncol
, vol.19
, Issue.9
, pp. 1613-1618
-
-
Telli, M.L.1
Witteles, R.M.2
Fisher, G.A.3
Srinivas, S.4
-
32
-
-
36849091849
-
Cardiac toxicity of sunitinib
-
Joensuu H. Cardiac toxicity of sunitinib. Lancet 2007; 370(9604):1978-1980.
-
(2007)
Lancet
, vol.370
, Issue.9604
, pp. 1978-1980
-
-
Joensuu, H.1
-
33
-
-
55949101031
-
Tyrosine kinase inhibitors: Can promising new therapy associated with cardiac toxicity strengthen the concept of teamwork?
-
Lenihan DJ. Tyrosine kinase inhibitors: can promising new therapy associated with cardiac toxicity strengthen the concept of teamwork? J Clin Oncol 2008; 26(32): 5154-5155.
-
(2008)
J Clin Oncol
, vol.26
, Issue.32
, pp. 5154-5155
-
-
Lenihan, D.J.1
-
34
-
-
33846181370
-
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, et al. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007; 356(2): 115-124.
-
(2007)
N Engl J Med
, vol.356
, Issue.2
, pp. 115-124
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
35
-
-
0036791599
-
Gut mucosal healing: Is the science relevant?
-
Basson MD. Gut mucosal healing: is the science relevant? Am J Pathol 2002; 161(4): 1101-1105.
-
(2002)
Am J Pathol
, vol.161
, Issue.4
, pp. 1101-1105
-
-
Basson, M.D.1
-
36
-
-
0036790429
-
Esophageal ulceration triggers expression of hypoxia-inducible factor-1 alpha and activates vascular endothelial growth factor gene: Implications for angiogenesis and ulcer healing
-
Baatar D, Jones MK, Tsugawa K, et al. Esophageal ulceration triggers expression of hypoxia-inducible factor-1 alpha and activates vascular endothelial growth factor gene: implications for angiogenesis and ulcer healing. Am J Pathol 2002; 161(4): 1449-1457.
-
(2002)
Am J Pathol
, vol.161
, Issue.4
, pp. 1449-1457
-
-
Baatar, D.1
Jones, M.K.2
Tsugawa, K.3
-
37
-
-
0034767707
-
Gene therapy for gastric ulcers with single local injection of naked DNA encoding VEGF and angiopoietin-1
-
Jones MK, Kawanaka H, Baatar D, et al. Gene therapy for gastric ulcers with single local injection of naked DNA encoding VEGF and angiopoietin-1. Gastroenterology 2001; 121(5): 1040-1047.
-
(2001)
Gastroenterology
, vol.121
, Issue.5
, pp. 1040-1047
-
-
Jones, M.K.1
Kawanaka, H.2
Baatar, D.3
-
38
-
-
75749090050
-
Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma
-
Hutson TE, Davis ID, Machiels JP, et al. Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma. J Clin Oncol 2009; 28(3): 475-480.
-
(2009)
J Clin Oncol
, vol.28
, Issue.3
, pp. 475-480
-
-
Hutson, T.E.1
Davis, I.D.2
Machiels, J.P.3
-
39
-
-
77951666852
-
Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism
-
Xu CF, Reck BH, Xue Z, et al. Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. Br J Cancer 2010; 102(9): 1371-1377.
-
(2010)
Br J Cancer
, vol.102
, Issue.9
, pp. 1371-1377
-
-
Xu, C.F.1
Reck, B.H.2
Xue, Z.3
-
40
-
-
80052223567
-
-
(package Insert) GSKI, Research Triangle, NC
-
Pazopanib, (package insert) GSKI, Research Triangle, NC. 2010.
-
(2010)
Pazopanib
-
-
-
41
-
-
33750961647
-
Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors
-
Desai J, Yassa L, Marqusee E, et al. Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. Ann Intern Med 2006; 145(9): 660-664.
-
(2006)
Ann Intern Med
, vol.145
, Issue.9
, pp. 660-664
-
-
Desai, J.1
Yassa, L.2
Marqusee, E.3
-
42
-
-
47549084773
-
Sunitinib-associated lymphocytic thyroiditis without circulating antithyroid antibodies
-
Alexandrescu DT, Popoveniuc G, Farzanmehr H, Dasanu CA, Dawson N, Wartofsky L. Sunitinib-associated lymphocytic thyroiditis without circulating antithyroid antibodies. Thyroid 2008; 18(7): 809-812.
-
(2008)
Thyroid
, vol.18
, Issue.7
, pp. 809-812
-
-
Alexandrescu, D.T.1
Popoveniuc, G.2
Farzanmehr, H.3
Dasanu, C.A.4
Dawson, N.5
Wartofsky, L.6
-
43
-
-
36749072043
-
Sunitinib (sutent)-induced thyrotoxicosis due to destructive thyroiditis: A case report
-
Faris JE, Moore AF, Daniels GH. Sunitinib (sutent)-induced thyrotoxicosis due to destructive thyroiditis: a case report. Thyroid 2007; 17(11): 1147-1149.
-
(2007)
Thyroid
, vol.17
, Issue.11
, pp. 1147-1149
-
-
Faris, J.E.1
Moore, A.F.2
Daniels, G.H.3
-
44
-
-
51649122915
-
Thyrotoxicosis during sunitinib treatment for renal cell carcinoma
-
Grossmann M, Premaratne E, Desai J, Davis ID. Thyrotoxicosis during sunitinib treatment for renal cell carcinoma. Clin Endocrinol (Oxf) 2008; 69(4): 669-672.
-
(2008)
Clin Endocrinol (Oxf)
, vol.69
, Issue.4
, pp. 669-672
-
-
Grossmann, M.1
Premaratne, E.2
Desai, J.3
Davis, I.D.4
-
45
-
-
38849093794
-
Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib
-
Tamaskar I, Bukowski R, Elson P, et al. Thyroid function test abnormalities in patients with metastatic renal cell carcinoma treated with sorafenib. Ann Oncol 2008; 19(2): 265-268.
-
(2008)
Ann Oncol
, vol.19
, Issue.2
, pp. 265-268
-
-
Tamaskar, I.1
Bukowski, R.2
Elson, P.3
-
46
-
-
33846978108
-
Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib
-
Rini BI, Tamaskar I, Shaheen P, et al. Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. J Natl Cancer Inst 2007; 99(1): 81-83.
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.1
, pp. 81-83
-
-
Rini, B.I.1
Tamaskar, I.2
Shaheen, P.3
-
47
-
-
34248632840
-
Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity
-
Wong E, Rosen LS, Mulay M, et al. Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity. Thyroid 2007; 17(4): 351-355.
-
(2007)
Thyroid
, vol.17
, Issue.4
, pp. 351-355
-
-
Wong, E.1
Rosen, L.S.2
Mulay, M.3
-
48
-
-
34548764576
-
A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake
-
Mannavola D, Coco P, Vannucchi G, et al. A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake. J Clin Endocrinol Metab 2007; 92(9): 3531-3534.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, Issue.9
, pp. 3531-3534
-
-
Mannavola, D.1
Coco, P.2
Vannucchi, G.3
-
49
-
-
68949145218
-
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
-
Motzer RJ, Hutson TE, Tomczak P, et al. Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma. J Clin Oncol 2009, 2009; 27(22): 3584-3590.
-
(2009)
J Clin Oncol 2009
, vol.27
, Issue.22
, pp. 3584-3590
-
-
Motzer, R.J.1
Hutson, T.E.2
Tomczak, P.3
-
50
-
-
77949890945
-
Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
-
Sternberg CN, Davis ID, Mardiak J, et al. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010; 28(6): 1061-1068.
-
(2010)
J Clin Oncol
, vol.28
, Issue.6
, pp. 1061-1068
-
-
Sternberg, C.N.1
Davis, I.D.2
Mardiak, J.3
-
51
-
-
66149121478
-
Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: A meta-analysis
-
Hapani S, Chu D, Wu S. Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysis. Lancet Oncol 2009; 10(6): 559-568.
-
(2009)
Lancet Oncol
, vol.10
, Issue.6
, pp. 559-568
-
-
Hapani, S.1
Chu, D.2
Wu, S.3
-
52
-
-
80052229242
-
-
Bevacizumab (package insert) Soth San Francisco
-
Genentec I, Bevacizumab (package insert) Soth San Francisco. 2009.
-
(2009)
-
-
Genentec, I.1
-
53
-
-
80052247095
-
Mammalian target of rapamycin (mTOR)-induced pneumonitis: Single-institution experience and treatment
-
Abstract e13520
-
Kahn DY, Mita AC, George BJ, et al. Mammalian target of rapamycin (mTOR)-induced pneumonitis: Single-institution experience and treatment. J Clin Oncol 2010; 28(suppl): Abstract e13520).
-
(2010)
J Clin Oncol
, vol.28
, Issue.1
-
-
Kahn, D.Y.1
Mita, A.C.2
George, B.J.3
-
54
-
-
1542398693
-
Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
-
Atkins MB, Hidalgo M, Stadler WM, et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J Clin Oncol 2004; 22(5): 909-918.
-
(2004)
J Clin Oncol
, vol.22
, Issue.5
, pp. 909-918
-
-
Atkins, M.B.1
Hidalgo, M.2
Stadler, W.M.3
-
55
-
-
66649133114
-
A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer
-
Amato RJ, Jac J, Giessinger S, Saxena S, Willis JP. A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer. Cancer 2009; 115(11): 2438-2446.
-
(2009)
Cancer
, vol.115
, Issue.11
, pp. 2438-2446
-
-
Amato, R.J.1
Jac, J.2
Giessinger, S.3
Saxena, S.4
Willis, J.P.5
-
56
-
-
77956626151
-
Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma
-
White DA, Camus P, Endo M, et al. Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma. Am J Respir Crit Care Med 2010; 182(3): 396-403.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, Issue.3
, pp. 396-403
-
-
White, D.A.1
Camus, P.2
Endo, M.3
-
57
-
-
48749128305
-
Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features
-
Bellmunt J, Szczylik C, Feingold J, Strahs A, Berkenblit A. Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features. Ann Oncol 2008; 19(8): 1387-1392.
-
(2008)
Ann Oncol
, vol.19
, Issue.8
, pp. 1387-1392
-
-
Bellmunt, J.1
Szczylik, C.2
Feingold, J.3
Strahs, A.4
Berkenblit, A.5
-
58
-
-
48649107474
-
Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
-
Motzer RJ, Escudier B, Oudard S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet2008; 372(9637): 449-456.
-
(2008)
Lancet
, vol.372
, Issue.9637
, pp. 449-456
-
-
Zer, R.J.1
Escudier, B.2
Oudard, S.3
-
59
-
-
34249779568
-
Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
-
Hudes G, Carducci M, Tomczak P, et al. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007; 356(22): 2271-2281.
-
(2007)
N Engl J Med
, vol.356
, Issue.22
, pp. 2271-2281
-
-
Hudes, G.1
Carducci, M.2
Tomczak, P.3
-
60
-
-
55049136730
-
Targeted therapies for metastatic renal cell carcinoma: An overview of toxicity and dosing strategies
-
Hutson TE, Figlin RA, Kuhn JG, Motzer RJ. Targeted therapies for metastatic renal cell carcinoma: an overview of toxicity and dosing strategies. Oncologist 2008; 13(10): 1084-1096.
-
(2008)
Oncologist
, vol.13
, Issue.10
, pp. 1084-1096
-
-
Hutson, T.E.1
Figlin, R.A.2
Kuhn, J.G.3
Motzer, R.J.4
-
61
-
-
0036014062
-
Effect of rifampin on apparent clearance of everolimus
-
Kovarik JM, Hartmann S, Figueiredo J, Rouilly M, Port A, Rordorf C. Effect of rifampin on apparent clearance of everolimus. Ann Pharmacother 2002; 36(6): 981-985.
-
(2002)
Ann Pharmacother
, vol.36
, Issue.6
, pp. 981-985
-
-
Kovarik, J.M.1
Hartmann, S.2
Figueiredo, J.3
Rouilly, M.4
Port, A.5
Rordorf, C.6
-
62
-
-
80052188603
-
-
(package insert) Novartis I
-
Everolimus, (package insert) Novartis I. 2010.
-
(2010)
Everolimus
-
-
-
63
-
-
2942735384
-
Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer
-
Raymond E, Alexandre J, Faivre S, et al. Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer. J Clin Oncol 2004; 22(12): 2336-2347.
-
(2004)
J Clin Oncol
, vol.22
, Issue.12
, pp. 2336-2347
-
-
Raymond, E.1
Alexandre, J.2
Faivre, S.3
-
64
-
-
79960359480
-
-
(package insert) WI
-
Temsirolimus, (package insert) WI. 2010.
-
(2010)
Temsirolimus
-
-
|