The vesicle size of DDA:TDB liposomal adjuvants plays a role in the cell-mediated immune response but has no significant effect on antibody production

Journal of Controlled Release

Volumn 154, Issue 2, 2011, Pages 131-137

  Henriksen Lacey, Malou ^a   Devitt, Andrew ^a   Perrie, Yvonne ^a  

^a ASTON UNIVERSITY   (United Kingdom)

Author keywords

Adjuvant; Biodistribution; Cationic liposome; Immunostimulatory; Vaccine

Indexed keywords

ADJUVANT; ANTIBODY PRODUCTION; BIODISTRIBUTIONS; CATIONIC LIPOSOMES; CELL-MEDIATED IMMUNE; CELLULAR UPTAKE; CLINICAL TRIAL; CYTOKINE PRODUCTION; DELIVERY VEHICLE; HETEROGENEOUS POPULATIONS; IMMUNE RESPONSE; IMMUNOSTIMULATORY; IN-VITRO; IN-VIVO; LYMPH NODE; MACROPHAGE-LIKE CELLS; PHASE I; SIZE-DEPENDENT EFFECT; SPLENOCYTES; VESICLE SIZE;

ANTIGENS; CELL PROLIFERATION; COMPLEXATION; LIPOSOMES; PHOSPHOLIPIDS; VACCINES;

IMMUNOLOGY;

ADJUVANT; COLECALCIFEROL; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; INTERLEUKIN 10; INTERLEUKIN 1BETA; LIPOSOME; MYCOBACTERIUM ANTIGEN; TREHALOSE DIBEHENATE; TUBERCULOSIS ANTIGEN AG85B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOSTIMULATION; INJECTION SITE; LYMPH NODE; MACROPHAGE; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SPLEEN CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODY FORMATION; CELLS, CULTURED; GLYCOLIPIDS; HUMANS; IMMUNITY, CELLULAR; LIPOSOMES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PARTICLE SIZE; QUATERNARY AMMONIUM COMPOUNDS; SPLEEN;

EID: 80052209319     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.05.019     Document Type: Article

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