Diagnosis of fulminant type 1 diabetes mellitus in an autopsy case with postmortem changes

Legal Medicine

Volumn 13, Issue 5, 2011, Pages 250-253

  Mizutani, Tatsushi ^a   Yoshimoto, Takashi ^a   Kaneko, Rina ^a   Ishii, Akira ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Hydroxybutyrate; Fulminant type 1 diabetes mellitus; Immunohistochemistry; Postmortem change

Indexed keywords

3 HYDROXYBUTYRIC ACID; ACETOACETIC ACID; ANTACID AGENT; ANTIINFECTIVE AGENT; C PEPTIDE; CD3 ANTIGEN; CD68 ANTIGEN; ELASTASE; EOSIN; HEMATOXYLIN; HEMOGLOBIN A1C; INSULIN ANTIBODY; KETONE BODY;

ABDOMEN; ACUTE GASTROENTERITIS; ADULT; AMYLASE BLOOD LEVEL; ARTICLE; AUTOLYSIS; AUTOPSY; BLADDER; BLEEDING; BLOOD; BODY FLUID; BODY HEIGHT; BODY WEIGHT; BRAIN; CADAVER; CELL DESTRUCTION; CELL INVASION; CELL VACUOLE; CHEMICAL ANALYSIS; CONJUNCTIVA; CONSTIPATION; CONSULTATION; CORNEA; CYSTIC FIBROSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FAT NECROSIS; FATTY LIVER; FEMALE; FEVER; FLANK PAIN; FULMINANT TYPE 1 DIABETES MELLITUS; GAS CHROMATOGRAPHY; GENERAL PRACTITIONER; GLUCOSE BLOOD LEVEL; HEART; HISTOPATHOLOGY; HUMAN; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; INSULIN DEPENDENT DIABETES MELLITUS; KETOACIDOSIS; KIDNEY; KIDNEY TUBULE CELL; LATEX AGGLUTINATION TEST; LIQUID CHROMATOGRAPHY; LIVER WEIGHT; LUNG EDEMA; MASS SPECTROMETRY; NAUSEA; NEUTROPHIL; PANCREAS; PANCREAS ISLET; PANCREAS ISLET BETA CELL; RADIOIMMUNOASSAY; SKIN DISCOLORATION; STAINING; TANDEM MASS SPECTROMETRY; URINE; VITREOUS BODY;

3-HYDROXYBUTYRIC ACID; ADULT; AUTOPSY; BODY FLUIDS; DIABETES MELLITUS, TYPE 1; DIABETIC KETOACIDOSIS; FEMALE; FORENSIC PATHOLOGY; HUMANS; JAPAN; POSTMORTEM CHANGES;

EID: 80052164162     PISSN: 13446223     EISSN: 18734162     Source Type: Journal    
DOI: 10.1016/j.legalmed.2011.05.007     Document Type: Article

References (18)

1. Coe J.I. Postmortem chemistry update. Am J Forensic Med Pathol 1993, 14:91-117.
2. Madea B., Musshoff F. Postmortem biochemistry. Forensic Sci Int 2007, 165:165-171.
3. Felby S., Nielsen E., Thomsen J.L. The postmortem distribution of ketone bodies between blood, vitreous humor, spinal fluid, and urine. Forensic Sci Med Pathol 2008, 4(2):100-107.
4. Hess C., Musshoff F., Madea B. Disorders of glucose metabolism-post mortem analyses in forensic cases: part 1. Int J Legal Med 2011, 125(2):163-170.
5. Hess C., Musshoff F., Madea B. Disorders of glucose metabolism-post mortem analyses in forensic cases: part 2. Int J Legal Med 2011, 125(2):171-180.
6. Hanafusa T., Imagawa A. Fulminant type 1 diabetes: a novel clinical entity requiring special attention by all medical practitioners. Nat Clin Pract Endocrinol Metab 2007, 3(1):36-45.
7. Ro A., Hisashi Y., Kageyama N., Tanifuji T., Hayashi K., Fukunaga T., et al. Two autopsy cases of sudden death in adolescents by fulminant type1 diabetes mellitus. Jpn J Forensic Pathol 2006, 12:22-26. [in Japanese].
8. Goto S., Abiru H., Iino M., Tamaki K. An autopsy of fulminant type 1 diabetes mellitus. Jpn J Legal Med 2005, 59:p201. [in Japanese].
9. Pharmaceutical Society of Japan, editor. Standard methods of chemical analysis in poisoning-with commentary. 5th ed. Tokyo: Nanzando; 1995, p. 14.
10. Uemura K., Shintani-Ishida K., Saka K., Nakajima M., Ikegawa H., Kikuchi Y., et al. Biochemical blood markers and sampling sites in forensic autopsy. J Forensic Leg Med 2008, 15(5):312-317.
11. Kikuchi H. Urine glucose and urine ketone bodies. In: Nippon Rinsho, vol. 67, Suppl. 8. Osaka: Nippon Rinsho-sha; 2009, p. 101-4 [in Japanese].
12. Kanetake J., Kanawaku Y., Mimasaka S., Sakai J., Hashiyada M., Nata M., et al. The relationship of a high level of serum beta-hydroxybutyrate to cause of death. Leg Med 2005, 7(3):169-174.
13. Osuma E., Vivero G., Conejero J., Abenza J.M., Martínez P., Luna A., et al. Postmortem vitreous humor beta-hydroxybutyrate: its utility for the postmortem interpretation of diabetes mellitus. Forensic Sci Int 2005, 29(153):189-195.
14. Satoh F., Fujita M., Seto Y., Tsuboi A., Hasegawa I., Takeuchi S. An autopsy case: sudden death due to diabetic ketoacidosis in diabetes mellitus 2 type. Jpn J Forensic Pathol 2005, 11:72-77. [in Japanese].
15. Nagata M., Moriyama H., Kotani R., Yasuda H., Kishi M., Kurohara M. Immunological aspects of 'fulminant type 1 diabetes'. Diabetes Res Clin Pract 2007, 77S:S99-S103.
16. Dayan C., Williams G. Diabetes. Oxford textbook of medicine 2010, Oxford University Press, New York. 5th ed. M.T. Cox, D.J. Firth (Eds.).
17. Hanafusa T., Imagawa A. Insulitis in human type 1 diabetes. Ann NY Acad Sci 2008, 1150:297-299.
18. Shibasaki S., Imagawa A., Tauriainen S., Iino M., Oikarinen M., Abiru H., et al. Expression of toll-like receptors in the pancreas of recent-onset fulminant type 1 diabetes. Endocr J 2010, 57(3):211-219.