CCBE1 Is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-c in vivo

Circulation Research

Volumn 109, Issue 5, 2011, Pages 486-491

  Bos, Frank L ^a,b   Caunt, Maresa ^c   Peterson Maduro, Josi ^a   Planas Paz, Lara ^d   Kowalski, Joe ^c   Karpanen, Terhi ^a   Van Impel, Andreas ^a   Tong, Raymond ^c   Ernst, James A ^c   Korving, Jeroen ^a   Van Es, Johan H ^a   Lammert, Eckhard ^d   Duckers, Henricus J ^b   Schulte Merker, Stefan ^a,e  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c GENENTECH INC   (United States)

^d HEINRICH HEINE UNIVERSITY   (Germany)

^e WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Ccbe1; Hennekam syndrome; lymphangiogenesis; mouse model; VEGF C

Indexed keywords

COLLAGEN AND CALCIUM BINDING ENDOTHELIAL GROWTH FACTOR DOMAINS 1; MUTANT PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 3;

ANIMAL EXPERIMENT; ARTICLE; BIOASSAY; CONTROLLED STUDY; CORNEAL MICROPOCKET ASSAY; EMBRYO; EMBRYO DEVELOPMENT; EXTRACELLULAR MATRIX; IN VITRO STUDY; IN VIVO STUDY; LYMPH VESSEL ENDOTHELIUM; LYMPHANGIOGENESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; CALCIUM-BINDING PROTEINS; CORNEA; ENDOTHELIUM, LYMPHATIC; HUMANS; LYMPHANGIOGENESIS; LYMPHATIC VESSELS; MICE; MICE, KNOCKOUT; PROTEIN BINDING; TUMOR SUPPRESSOR PROTEINS; VASCULAR ENDOTHELIAL GROWTH FACTOR C;

EID: 80052161700     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.250738     Document Type: Article

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