Reversible bone marrow reticulin fibrosis as a side effect of romiplostim therapy for the treatment of chronic refractory immune thrombocytopenia

Pathology

Volumn 43, Issue 5, 2011, Pages 520-522

  Leung, Teresa ^a   Lokan, Julie ^b   Turner, Paul ^a   Smith, Carole ^a  

^a Departments of Haematology   (Australia)

^b AUSTIN HEALTH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 80052107032     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1097/PAT.0b013e328348fecc     Document Type: Letter

References (9)

1. Provan D, Stasi R, Newland A, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood 2010; 115: 168-86.
2. George JN. Management of patients with refractory immune thrombocytopenic purpura. J Thromb Haemost 2006; 4: 1664-72.
3. Cuker A. Toxicities of the thrombopoietic growth factors. Semin Haematol 2010; 47: 289-98.
4. Kimura A, Katoh O, Hyodo H, Kuramoto A. Transforming growth factorbeta regulates growth as well as collagen and fibronectin synthesis of human marrow fibroblasts. Br J Haematol 1989; 72: 486-91.
5. Mufti G, Hassaerjian R, Bain B, Kuter D, Dreiling L, Nichol J. Bone marrow reticulin in patient with immune thrombocytopenic pupura. Blood 2006; 108: Abstr 3982.
6. Swerdlow SH, Campo E, Harris NL, et al., editors. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th ed. Lyon: IARC, 2008; 45-6.
7. Thiele J, Kvasnicka HM, Facchetti F, Franco V, van der Walt J, Orazi A. European consensus on grading bone marrow fibrosis and assessment of cellularity. Haematologica 2005; 90: 1128-32.
8. Bussel JB, Kuter DJ, Pullarkat V, Lyons RM, Guo M, Nichol JL. Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP. Blood 2009; 113: 2161-71.
9. Kuter DJ, Mufti GJ, Bain BJ, Hasserjian RP, Davis W, Rutstein M. Evaluation of bone marrow reticulin formation in chronic immune thrombocytopenia patients treated with romiplostim. Blood 2009; 114: 3748-56.