Multi-site monitoring of choline and glutamate using biosensor microprobe arrays in combination with CMOS circuitry

2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Volumn , Issue , 2011, Pages 1829-1832

  Frey, O ^a   Rothe, J ^a   Lewandowska, M K ^a   Van Der Wal, P D ^b   De Rooij, N F ^b   Hierlemann, A ^a  

^a ETH ZURICH   (Switzerland)

^b EPFL   (Switzerland)

Author keywords

Biosensor; choline; CMOS; L glutamate; microprobe

Indexed keywords

CHOLINE; CIRCUITRY CHIPS; CMOS; CMOS CHIPS; DETECTION LIMITS; ELECTROCHEMICAL DEPOSITION; FUNCTIONALIZATIONS; HIGH SIGNAL-TO-NOISE RATIO; IN-VIVO; L-GLUTAMATE; MICRO-PROBES; MICROPROBE ARRAYS; MULTI-SITE; MULTIPLE AREAS; ON-SITE MEASUREMENT; POTENTIOSTATICS;

ACTUATORS; ELECTROCHEMICAL ELECTRODES; ENZYME ELECTRODES; FADING (RADIO); MICROSYSTEMS; REDUCTION; SIGNAL TO NOISE RATIO;

SOLID-STATE SENSORS;

EID: 80052104975     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/TRANSDUCERS.2011.5969298     Document Type: Conference Paper

References (5)

1. M. Fillenz, "In vivo neurochemical monitoring and the study of behaviour," Neuroscience and Biobehavioral Reviews, Vol. 29, pp. 949-962, 2005.
2. S. Herwik, S. Kisban, A. A. A. Aarts, K. Seidl, G. Girardeau, K. Benchenane, M. B. Zugaro, S. I. Wiener, O. Paul, H. P. Neves, P. Ruther, "Fabrication technology for silicon-based microprobe arrays used in acute and sub-chronic neural recording", Journal of Micromechanics and Microengineering, Vol. 19, 074008, 2009.
3. O. Frey, T. Holtzman, R. M. McNamara, D. E. Theobald, P. D. van der Wal, N. F. de Rooij, J. W. Dalley, M. Koudelka-Hep, "Enzyme-based choline and L-glutamate biosensor electrodes on silicon microprobe arrays", Biosensors and Bioelectronics, Vol. 26, pp. 477-484, 2010.
4. F. Heer, M. Keller, G. Yu, J. Janata, M. Josowicz, A. Hierlemann, "CMOS electro-chemical DNA-detection array with on-chip ADC," Digest Tech Paper, IEEE Int. Solid-State Circuits Conference, San Francisco, USA, 2008, pp. 168-604.
5. J. Rothe, M. K. Lewandowska, F. Heer, O. Frey, A. Hierlemann, "Multi-target electrochemical biosensing enabled by integrated CMOS electronics", Journal of Micromechanics and Microengineering-Special issue: MEMS in Biology and Medicine (Expected online publication: April 2011; print May 2011)