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Angewandte Chemie - International Edition

Volumn 50, Issue 36, 2011, Pages 8407-8411

Synthesis of withanolide A, biological evaluation of its neuritogenic properties, and studies on secretase inhibition

(6) Jana, Chandan Kumar a Hoecker, Johannes a Woods, Tom M b Jessen, Henning J a Neuburger, Markus a Gademann, Karl a

a UNIVERSITY OF BASEL (Switzerland)

b UNIVERSITY OF AUCKLAND (New Zealand)

Author keywords

chemical biology; natural products; neurochemistry; steroids; total synthesis

Indexed keywords

CHEMICAL BIOLOGY; NATURAL PRODUCTS; NEUROCHEMISTRY; STEROIDS; TOTAL SYNTHESIS;

BIOCHEMISTRY; CONDENSATION REACTIONS; LIPIDS; NEURONS; STEREOCHEMISTRY; STEREOSELECTIVITY;

SYNTHESIS (CHEMICAL);

3 RHAMNOPYRANOSYL(1 4) GLUCOPYRANOSYL 12 DIACETOXY 20 HYDROXYWITHA 5,24 DIENOLIDE; 3-RHAMNOPYRANOSYL(1-4)-GLUCOPYRANOSYL-12-DIACETOXY-20-HYDROXYWITHA-5,24-DIENOLIDE; SECRETASE; SINGLET OXYGEN; WITHANOLIDE;

ARTICLE; CELL DIFFERENTIATION; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; METABOLISM; NEURITE; PHYSIOLOGY; STEREOISOMERISM; SYNTHESIS; TUMOR CELL LINE; WITHANIA; X RAY CRYSTALLOGRAPHY;

AMYLOID PRECURSOR PROTEIN SECRETASES; CELL DIFFERENTIATION; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; HUMANS; MOLECULAR CONFORMATION; NEURITES; SINGLET OXYGEN; STEREOISOMERISM; WITHANIA; WITHANOLIDES;

EID: 80052099473 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201101869 Document Type: Article

Times cited : (48)

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