Prolonged hepatomegaly in mice that cannot inactivate bacterial endotoxin

Hepatology

Volumn 54, Issue 3, 2011, Pages 1051-1062

  Shao, Baomei ^a   Kitchens, Richard L ^a   Munford, Robert S ^a,b   Rogers, Thomas E ^a   Rockey, Don C ^a   Varley, Alan W ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLOXYACYL HYDROLASE; DEXAMETHASONE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IBUPROFEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; LOW MOLECULAR WEIGHT HEPARIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; N(G) NITRO DEXTRO ARGININE METHYL ESTER; N(G) NITROARGININE METHYL ESTER; PEGSUNERCEPT; RANTES; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; SUPPRESSOR OF CYTOKINE SIGNALING 1; TOCILIZUMAB; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL SELECTION; CONTROLLED STUDY; DENDRITIC CELL; ENDOTHELIUM CELL; HEPATOMEGALY; KUPFFER CELL; LEUKOCYTE AGGREGATION; LIVER CELL DAMAGE; LIVER LEVEL; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

ANIMALS; CARBOXYLIC ESTER HYDROLASES; CELL PROLIFERATION; CYTOKINES; ENDOTHELIAL CELLS; HEPATOMEGALY; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LYMPHOCYTE ANTIGEN 96; MICE; NITRIC OXIDE SYNTHASE; TOLL-LIKE RECEPTOR 4;

EID: 80052037518     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24488     Document Type: Article

References (31)

1. Bilzer M, Roggel F, Gerbes AL. Role of Kupffer cells in host defense and liver disease. Liver Int 2006; 26: 1175-1186.
2. Nolan JP. Endotoxin, reticuloendothelial function, and liver injury. HEPATOLOGY 1981; 1: 458-465.
3. Scott MJ, Billiar TR. Beta 2-integrin induced p38MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of LPS by hepatocytes. J Biol Chem 2008; 283: 29433-29446.
4. Szabo G, Romics L Jr, Frendl G. Liver in sepsis and systemic inflammatory response syndrome. Clin Liver Dis 2002; 6: 1045-1066, x.
5. Poelstra K, Bakker WW, Klok PA, Hardonk MJ, Meijer DKF. A physiologic function for alkaline phosphatase: endotoxin detoxification. Lab Invest 1997; 76: 319-327.
6. Shao B, Lu M, Katz SC, Varley AW, Hardwick J, Rogers TE, et al. A host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen. J Biol Chem 2007; 282: 13726-13735.
7. Su GL. Lipopolysaccharides in liver injury: molecular mechanisms of Kupffer cell activation. Am J Physiol Gastrointest Liver Physiol 2002; 283: G256-G265.
8. Szabo G, Bala S. Alcoholic liver disease and the gut-liver axis. World J Gastroenterol 2010; 16: 1321-1329.
9. Browning JD, Horton JD. Molecular mediators of hepatic steatosis and liver injury. J Clin Invest 2004; 114: 147-152.
10. Pastor CM, Billiar TR, Losser MR, Payen DM. Liver injury during sepsis. J Crit Care 1995; 10: 183-197.
11. Munford R, Lu M, Varley A. Chapter 2: kill the bacteria... and also their messengers? Adv Immunol 2009; 103: 29-48.
12. Minei JP, Fong Y, Marano MA, Moldawer LL, Jones WG, Wei H, et al. Hepatocellular membrane function during chronic burn injury. J Surg Res 1989; 46: 311-316.
13. Margenthaler JA, Landeros K, Kataoka M, Eilers M, Ku G, Flye MW. Effects of endotoxin tolerance on Propionibacterium acnes-primed lipopolysaccharide hepatic injury. J Surg Res 2003; 112: 102-110.
14. Vary TC, Kimball SR. Regulation of hepatic protein synthesis in chronic inflammation and sepsis. Am J Physiol 1992; 262(2 Pt 1): C445-C452.
15. Brosnan JT, Qian D. Endotoxin-induced increase in liver mass and hepatocyte volume. Biochem Soc Trans 1994; 22: 529-532.
16. Feingold KR, Grunfeld C. Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo. J Clin Invest 1987; 80: 184-190.
17. Hall CL, Munford RS. Enzymatic deacylation of the lipid A moiety of Salmonella typhimurium lipopolysaccharides by human neutrophils. Proc Natl Acad Sci U S A 1983; 80: 6671-6675.
18. Lu M, Zhang M, Kitchens RL, Fosmire S, Takashima A, Munford RS. Stimulus-dependent deacylation of bacterial lipopolysaccharide by dendritic cells. J Exp Med 2003; 197: 1745-1754.
19. Ohta S, Bahrun U, Shimazu R, Matsushita H, Fukudome K, Kimoto M. Induction of long-term lipopolysaccharide tolerance by an agonistic monoclonal antibody to the toll-like receptor 4/MD-2 complex. Clin Vaccine Immunol 2006; 13: 1131-1136.
20. Lu M, Varley AW, Ohta S, Hardwick J, Munford RS. Host inactivation of bacterial lipopolysaccharide prevents prolonged tolerance following gram-negative bacterial infection. Cell Host Microbe 2008; 4: 293-302.
21. Ledda-Columbano GM, Curto M, Piga R, Zedda AI, Menegazzi M, Sartori C, et al. In vivo hepatocyte proliferation is inducible through a TNF and IL-6-independent pathway. Oncogene 1998; 17: 1039-1044.
22. Vestweber D. VE-cadherin: the major endothelial adhesion molecule controlling cellular junctions and blood vessel formation. Arterioscler Thromb Vasc Biol 2008; 28: 223-232.
23. Sarphie TG, Deaciuc IV, Spitzer JJ, D'Souza NB. Liver sinusoid during chronic alcohol consumption in the rat: an electron microscopic study. Alcohol Clin Exp Res 1995; 19: 291-298.
24. Freudenberg MA, Freudenberg N, Galanos C. Time course of cellular distribution of endotoxin in liver, lungs and kidneys of rats. Br J Exp Pathol 1982; 63: 56-65.
25. Chen T, Zamora R, Zuckerbraun B, Billiar TR. Role of nitric oxide in liver injury. Curr Mol Med 2003; 3: 519-526.
26. Cauwels A, Buys ES, Thoonen R, Geary L, Delanghe J, Shiva S, et al. Nitrite protects against morbidity and mortality associated with TNF- or LPS-induced shock in a soluble guanylate cyclase-dependent manner. J Exp Med 2009; 206: 2915-2924.
27. Huber M, Kalis C, Keck S, Jiang Z, Georgel P, Du X, et al. R-form LPS, the master key to the activation ofTLR4/MD-2-positive cells. Eur J Immunol 2006; 36: 701-711.
28. Miyazawa Y, Tsutsui H, Mizuhara H, Fujiwara H, Kaneda K. Involvement of intrasinusoidal hemostasis in the development of concanavalin A-induced hepatic injury in mice. HEPATOLOGY 1998; 27: 497-506.
29. Izeboud CA, Hoebe KH, Grootendorst AF, Nijmeijer SM, van Miert AS, Witkamp RR, et al. Endotoxin-induced liver damage in rats is minimized by beta 2-adrenoceptor stimulation. Inflamm Res 2004; 53: 93-99.
30. Abraham E, Kaneko DJ, Shenkar R. Effects of endogenous and exogenous catecholamines on LPS-induced neutrophil trafficking and activation. Am J Physiol Lung Cell Mol Physiol 1999; 276: L1-L8.
31. Oben JA, Diehl AM. Sympathetic nervous system regulation of liver repair. Anat Rec A Discov Mol Cell Evol Biol 2004; 280: 874-883.