Kirenol upregulates nuclear Annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in rats

Journal of Ethnopharmacology

Volumn 137, Issue 1, 2011, Pages 774-782

  Wang, Zhe Ming ^a   Zhu, Shi Gong ^a   Wu, Zai Wang ^a   Lu, Yue ^a   Fu, Hong Zheng ^a   Qian, Rui Qin ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Annexin 1; Collagen induced arthritis (CIA); Glucocorticoid receptor (GR); Glucocorticoid resistance; Herba Siegesbeckia; Kirenol; NF B; Rheumatoid arthritis (RA)

Indexed keywords

ANNEXIN; ANNEXIN 1; ANTIRHEUMATIC AGENT; COLLAGEN; CORTICOTROPIN; GLUCOCORTICOID RECEPTOR ALPHA; HERBACEOUS AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; KIRENOL; PREDNISOLONE; PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; DNA BINDING; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; DRUG STRUCTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; HISTOPATHOLOGY; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SWELLING; SYNOVIAL FLUID; SYNOVITIS; SYNOVIUM; UPREGULATION; WESTERN BLOTTING;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ANNEXIN A1; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; BINDING SITES; BLOTTING, WESTERN; CELL NUCLEUS; COLLAGEN TYPE II; DITERPENES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MALE; NF-KAPPA B; PREDNISOLONE; RATS; RATS, WISTAR; RECEPTORS, GLUCOCORTICOID; SYNOVIAL MEMBRANE; TIME FACTORS; UP-REGULATION;

RATTUS; SIEGESBECKIA;

EID: 80052036737     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.06.037     Document Type: Article

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