Glycated hemoglobin predicts all-cause, cardiovascular, and cancer mortality in people without a history of diabetes undergoing coronary angiography

Diabetes Care

Volumn 34, Issue 6, 2011, Pages 1355-1361

  Silbernagel, Guenther ^a,b   Grammer, Tanja B ^c   Winkelmann, Bernhard R ^d   Boehm, Bernhard O ^e   März, Winfried ^c,f,g  

^a Ludwigshafen Risk and Cardiovascular Study Non profit LLC   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d Cardiology Group Frankfurt Sachsenhausen   (Germany)

^e UNIVERSITY OF ULM   (Germany)

^f MEDICAL UNIVERSITY OF GRAZ   (Austria)

^g SYNLAB ACADEMY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; C REACTIVE PROTEIN; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

AGE; ANGIOCARDIOGRAPHY; ARTICLE; BODY MASS; CANCER MORTALITY; CAUCASIAN; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORRELATION ANALYSIS; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; DISEASE SEVERITY; EXERCISE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERTENSION; INSULIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MORTALITY; ORAL GLUCOSE TOLERANCE TEST; PHYSICAL ACTIVITY; PREDICTION; PREDICTIVE VALUE; SEDENTARY LIFESTYLE; SEX DIFFERENCE; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE;

ADULT; AGED; BLOOD GLUCOSE; CARDIOVASCULAR DISEASES; COMORBIDITY; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DIABETES MELLITUS, TYPE 2; FEMALE; FOLLOW-UP STUDIES; GERMANY; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; RISK;

EID: 80052003268     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc10-2010     Document Type: Article

References (25)

1. Selvin E., Crainiceanu C.M., Brancati F.L., Coresh J. Short-term variability in measures of glycemia and implications for the classification of diabetes. Arch Intern Med 2007;167:1545-1551 (Pubitemid 47124186)
2. American Diabetes Association. Standards of medical care in diabetes-2009. Diabetes Care 2009;32(Suppl. 1):S13-S61
3. Nathan D.M., Kuenen J., Borg R., Zheng H., Schoenfeld D., Heine R.J.; A1c-Derived Average Glucose Study Group. Translating the A1C assay into estimated average glucose values. Diabetes Care 2008;31:1473-1478
4. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2010;33(Suppl. 1):S62-S69
5. Selvin E., Steffes M.W., Zhu H., et al. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med 2010;362:800-811
6. Winkelmann B.R., Marz W., Boehm B.O., et al.; LURIC Study Group (Ludwigshafen Risk and Cardiovascular Health). Rationale and design of the LURIC study - a resource for functional genomics, pharmacogenomics and long-term prognosis of cardiovascular disease. Pharmacogenomics 2001;2(Suppl. 1):S1-S73
7. Friesinger G.C., Page E.E., Ross R.S. Prognostic significance of coronary arteriography. Trans Assoc Am Physicians 1970;83:78-92
8. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2009;32(Suppl. 1):S62-S67
9. De Groot V., Beckerman H., Lankhorst G.J., Bouter L.M. How to measure comorbidity: A critical review of available methods. J Clin Epidemiol 2003;56:221-229 (Pubitemid 36513483)
10. De Vegt F., Dekker J.M., Ruhé H.G., et al. Hyperglycaemia is associated with allcause and cardiovascular mortality in the Hoorn population: The Hoorn Study. Diabetologia 1999;42:926-931 (Pubitemid 29369599)
11. Khaw K.T., Wareham N., Bingham S., Luben R., Welch A., Day N. Association of hemoglobin A1c with cardiovascular disease and mortality in adults: The European Prospective Investigation into Cancer in Norfolk. Ann Intern Med 2004;141:413-420
12. Levitan E.B., Liu S., Stampfer M.J., et al. HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women. Diabetologia 2008;51:267-275
13. Gerstein H.C., Swedberg K., Carlsson J., et al.; CHARM Program Investigators. The hemoglobin A1c level as a progressive risk factor for cardiovascular death, hospitalization for heart failure, or death in patients with chronic heart failure: An analysis of the Candesartan in Heart failure: An analysis of the Candesartan in Heart failureAssessment of Reduction in Mortality and Morbidity (CHARM) program. Arch Intern Med 2008;168:1699-1704
14. Sarwar N., Aspelund T., Eiriksdottir G., et al. Markers of dysglycaemia and risk of coronary heart disease in people without diabetes: Reykjavik prospective study and systematic review. PLoS Med 2010 25;7:e1000278
15. McNeely M.J., McClelland R.L., Bild D.E., et al. The association between A1C and subclinical cardiovascular disease: The multi-ethnic study of atherosclerosis. Diabetes Care 2009;32:1727-1733
16. Brewer N., Wright C.S., Travier N., et al. A New Zealand linkage study examining the associations between A1C concentration and mortality. Diabetes Care 2008;31:1144-1149
17. Stout R.L., Fulks M., Dolan V.F., Magee M.E., Suarez L. Relationship of hemoglobin A1c to mortality in nonsmoking insurance applicants. J Insur Med 2007;39:174-181
18. Wei M., Gibbons L.W., Mitchell T.L., Kampert J.B., Stern M.P., Blair S.N. Low fasting plasma glucose level as a predictor of cardiovascular disease and all-cause mortality. Circulation 2000;101:2047-2052 (Pubitemid 30233167)
19. Selvin E., Zhu H., Brancati F.L. Elevated A1C in adults without a history of diabetes in the U.S. Diabetes Care 2009;32:828-833
20. Zhang X., Gregg E.W., Williamson D.F., et al. A1C level and future risk of diabetes: A systematic review. Diabetes Care 2010;33:1665-1673
21. Carson A.P., Reynolds K., Fonseca V.A., Muntner P. Comparison of A1C and fasting glucose criteria to diagnose diabetes among U.S. adults. Diabetes Care 2010;33:95-97
22. Selvin E., Steffes M.W., Gregg E., Brancati F.L., Coresh J. Performance of A1C for the classification and prediction of diabetes. Diabetes Care 2011;34:84-89
23. Meigs J.B., Nathan D.M., D'Agostino R.B. Sr, Wilson P.W.; Framingham Offspring Study. Fasting and postchallenge glycemia and cardiovascular disease risk: The Framingham Offspring Study. Diabetes Care 2002;25:1845-1850 (Pubitemid 41071098)
24. Woerle H.J., Pimenta W.P., Meyer C., et al. Diagnostic and therapeutic implications of relationships between fasting, 2-hour postchallenge plasma glucose and hemoglobin A1c values. Arch Intern Med 2004;164:1627-1632 (Pubitemid 39037941)
25. Herman W.H., Ma Y., Uwaifo G., et al.; Diabetes Prevention Program Research Group. Differences in A1C by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program. Diabetes Care 2007;30:2453-2457 (Pubitemid 47547771)