G-protein coupled receptors virtual screening using genetic algorithm focused chemical space

Journal of Chemical Information and Modeling

Volumn 51, Issue 8, 2011, Pages 1754-1761

  Sage, Carleton ^a   Wang, Runtong ^a   Jones, Gareth ^a  

^a ARENA PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DATABASE SYSTEMS; LIGANDS; PROTEINS;

BIOLOGICAL TARGETS; CHEMICAL SPACE; EARLY SELECTION; G PROTEIN COUPLED RECEPTORS; HIGHLY-CORRELATED; IMPROVE PERFORMANCE; POTENTIAL DRUG TARGETS; VIRTUAL SCREENING;

GENETIC ALGORITHMS;

G PROTEIN COUPLED RECEPTOR; LIGAND;

ALGORITHM; ANIMAL; ARTICLE; BINDING SITE; CHEMISTRY; COMPUTER INTERFACE; COMPUTER PROGRAM; DRUG ANTAGONISM; DRUG DELIVERY SYSTEM; DRUG DEVELOPMENT; DRUG POTENTIATION; FACTUAL DATABASE; HIGH THROUGHPUT SCREENING; HUMAN; METABOLISM; METHODOLOGY; MOUSE; PROTEIN BINDING; RAT; STATISTICS;

ALGORITHMS; ANIMALS; BINDING SITES; CHEMISTRY, PHARMACEUTICAL; DATABASES, FACTUAL; DRUG DELIVERY SYSTEMS; DRUG DISCOVERY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; MICE; PROTEIN BINDING; RATS; RECEPTORS, G-PROTEIN-COUPLED; SOFTWARE; USER-COMPUTER INTERFACE;

EID: 80051995202     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci200043z     Document Type: Article

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