-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A, Siegel R, Ward E, et al.: Cancer statistics, 2009. CA Cancer J Clin 2009; 59: 225-249
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
3
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J:, Tumor angiogenesis: Therapeutic implications. N Engl J Med 1971; 285: 1182-1186.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
4
-
-
23444434188
-
Microvessel density for melanoma prognosis
-
DOI 10.1111/j.1365-2559.2005.02193.x
-
Depasquale I, Thompson WD:, Microvessel density for melanoma prognosis. Histopathology 2005; 47: 186-194. (Pubitemid 41113122)
-
(2005)
Histopathology
, vol.47
, Issue.2
, pp. 186-194
-
-
Depasquale, I.1
Thompson, W.D.2
-
5
-
-
0015291143
-
Tumor angiogenesis: A quantitative method for histologic grading
-
Brem S, Cotran R, Folkman J:, Tumor angiogenesis: A quantitative method for histologic grading. J Natl Cancer Inst 1972; 48: 347-356.
-
(1972)
J Natl Cancer Inst
, vol.48
, pp. 347-356
-
-
Brem, S.1
Cotran, R.2
Folkman, J.3
-
6
-
-
0024208863
-
The prognostic significance of tumor vascularity in intermediate- thickness (0.76-4.0 mm thick) skin melanoma. A quantitative histologic study
-
Srivastava A, Laidler P, Davies RP, et al.: The prognostic significance of tumor vascularity in intermediate thickness (0.76-4.0 mm thick) skin melanoma. A quantitative histologic study. Am J Pathol 1988; 133: 419-423. (Pubitemid 19017504)
-
(1988)
American Journal of Pathology
, vol.133
, Issue.2
, pp. 419-423
-
-
Srivastava, A.1
Laidler, P.2
Davies, R.P.3
Horgan, K.4
Hughes, L.E.5
-
7
-
-
0031002117
-
Angiogenesis and malignant melanoma. Angiogenesis is related to the development of vertical (tumorigenic) growth phase
-
Marcoval P, Moreno A, Graelis J, et al.: Angiogenesis and malignant melanoma. Angiogenesis is related to the development of vertical (tumorigenic) growth phase. J Cutan Pathol 1997; 24: 212-218. (Pubitemid 27187016)
-
(1997)
Journal of Cutaneous Pathology
, vol.24
, Issue.4
, pp. 212-218
-
-
Marcoval, J.1
Moreno, A.2
Graells, J.3
Vidal, A.4
Escriba, J.M.5
Garcia-Ramirez, M.6
Fabra, A.7
-
8
-
-
0035863552
-
Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival
-
Ugurel S, Rappl G, Tilgen W, et al.: Increased serum concentration of angiogenic factors in malignant melanoma patients correlates with tumor progression and survival. J Clin Oncol 2001; 19: 577-583. (Pubitemid 32112873)
-
(2001)
Journal of Clinical Oncology
, vol.19
, Issue.2
, pp. 577-583
-
-
Ugurel, S.1
Rappl, G.2
Tilgen, W.3
Reinhold, U.4
-
9
-
-
77954668887
-
Angiogenesis inhibitors: Current strategies and future prospects
-
Cook KM, Figg WD:, Angiogenesis inhibitors: Current strategies and future prospects. CA Cancer J Clin 2010; 60: 222-243.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 222-243
-
-
Cook, K.M.1
Figg, W.2
-
10
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
DOI 10.1056/NEJMoa032691
-
Hurwitz H, Fehrenbacher L, Novotny W, et al.: Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-2342. (Pubitemid 38702844)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
Cartwright, T.4
Hainsworth, J.5
Heim, W.6
Berlin, J.7
Baron, A.8
Griffing, S.9
Holmgren, E.10
Ferrara, N.11
Fyfe, G.12
Rogers, B.13
Ross, R.14
Kabbinavar, F.15
-
11
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al.: Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007; 357: 2666-2676.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
12
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
DOI 10.1056/NEJMoa061884
-
Sandler A, Gray R, Perry MC, et al.: Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006; 355: 2542-2550. (Pubitemid 44917502)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
Lilenbaum, R.7
Johnson, D.H.8
-
13
-
-
34547451603
-
A randomized phase 2 trial of bevacizumab with or without daily low-dose interferon alfa-2b in metastatic malignant melanoma
-
DOI 10.1245/s10434-007-9389-5
-
Varker KA, Biber JE, Kefauver C, et al.: A randomized phase 2 trial of bevacizumab with or without daily low-dose interferon alfa-2b in metastatic malignant melanoma. Ann Surg Oncol 2007; 14: 2367-2376. (Pubitemid 47174913)
-
(2007)
Annals of Surgical Oncology
, vol.14
, Issue.8
, pp. 2367-2376
-
-
Varker, K.A.1
Biber, J.E.2
Kefauver, C.3
Jensen, R.4
Lehman, A.5
Young, D.6
Wu, H.7
Lesinski, G.B.8
Kendra, K.9
Chen, H.X.10
Walker, M.J.11
Carson III, W.E.12
-
14
-
-
80052004077
-
Phase II trial of nab-paclitaxel and bevacizumab as first-line therapy in patients with unresectable melanoma
-
abstract 8543.
-
Boasberg PD:, Phase II trial of nab-paclitaxel and bevacizumab as first-line therapy in patients with unresectable melanoma. J Clin Oncol 2011; 29 (suppl): abstract 8543.
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Boasberg, P.1
-
15
-
-
33751583518
-
Drug Insight: Vascular disrupting agents and angiogenesis - Novel approaches for drug delivery
-
DOI 10.1038/ncponc0663, PII NCPONC0663
-
Cooney M, van Heeckeren W, Bhakta S, et al.: Drug insight: Vascular disrupting agents and angiogenesis-Novel approaches for drug delivery. Nat Rev Clin Oncol 2006; 3: 682-692. (Pubitemid 44843126)
-
(2006)
Nature Clinical Practice Oncology
, vol.3
, Issue.12
, pp. 682-692
-
-
Cooney, M.M.1
Van Heeckeren, W.2
Bhakta, S.3
Ortiz, J.4
Remick, S.C.5
-
16
-
-
78649593334
-
Final report: Combination of MPC-6827 with temozolomide for the treatment of patients with metastatic melanoma
-
abstract 8531
-
Hwu W, Akerley WL, Stephenson J, et al.: Final report: Combination of MPC-6827 with temozolomide for the treatment of patients with metastatic melanoma. J Clin Oncol 2010; 28 (15s): abstract 8531.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 S
-
-
Hwu, W.1
Akerley, W.L.2
Stephenson, J.3
-
17
-
-
33646155553
-
Kit and melanocyte migration
-
Grichnik JM:, Kit and melanocyte migration. Invest Dermatol 2006; 126: 945-947.
-
(2006)
Invest Dermatol
, vol.126
, pp. 945-947
-
-
Grichnik, J.1
-
18
-
-
42949128595
-
Major response to imatinib mesylate in KIT-mutated melanoma
-
Hodi FS:, Major response to imatinib mesylate in KIT-mutated melanoma. J Clin Oncol 2008; 26: 2046-2051.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2046-2051
-
-
Hodi, F.1
-
19
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
DOI 10.1038/nature00766
-
Davies H, Bignell GR, Cox C, et al.: Mutations of the BRAF gene in human cancer. Nature 2002; 417: 949-954. (Pubitemid 34716871)
-
(2002)
Nature
, vol.417
, Issue.6892
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
Teague, J.7
Woffendin, H.8
Garnett, M.J.9
Bottomley, W.10
Davis, N.11
Dicks, E.12
Ewing, R.13
Floyd, Y.14
Gray, K.15
Hall, S.16
Hawes, R.17
Hughes, J.18
Kosmidou, V.19
Menzies, A.20
Mould, C.21
Parker, A.22
Stevens, C.23
Watt, S.24
Hooper, S.25
Wilson, R.26
Jayatilake, H.27
Gusterson, B.A.28
Cooper, C.29
Shipley, J.30
Hargrave, D.31
Pritchard-Jones, K.32
Maitland, N.33
Chenevix-Trench, G.34
Riggins, G.J.35
Bigner, D.D.36
Palmleri, G.37
Cossu, A.38
Flanagan, A.39
Nicholson, A.40
Ho, J.W.C.41
Leung, S.Y.42
Yuen, S.T.43
Weber, B.L.44
Seigler, H.F.45
Darrow, T.L.46
Paterson, H.47
Marais, R.48
Marshall, C.J.49
Wooster, R.50
Stratton, M.R.51
Futreal, P.A.52
more..
-
20
-
-
0242468891
-
CI-140 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)
-
Allen LF, Sebolt-Leopold J, Meyer MB:, CI-140 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK). Semin Oncol 2003; 30: 105-166.
-
(2003)
Semin Oncol
, vol.30
, pp. 105-166
-
-
Allen, L.F.1
Sebolt-Leopold, J.2
Meyer, M.3
-
21
-
-
36849085325
-
Genetics of melanoma tumorigenesis
-
DOI 10.1111/j.1365-2133.2007.08316.x
-
Singh M, Lin J, Hocker TL, et al.: Genetics of melanoma tumorigenesis. Br J Dermatol 2008; 158: 15-21. (Pubitemid 350221925)
-
(2008)
British Journal of Dermatology
, vol.158
, Issue.1
, pp. 15-21
-
-
Singh, M.1
Lin, J.2
Hocker, T.L.3
Tsao, H.4
-
22
-
-
67651246671
-
Phase i study of PLX4032: Proof of concept for V600E BRAF mutation as a therapeutic target in human cancer
-
abstract 9000.
-
Flaherty KT, Puzanov I, Sosman J, et al.: Phase I study of PLX4032: Proof of concept for V600E BRAF mutation as a therapeutic target in human cancer. J Clin Oncol 2009; 27 (15s): abstract 9000.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15 S
-
-
Flaherty, K.T.1
Puzanov, I.2
Sosman, J.3
-
23
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al.: Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011; 364: 2507-2516.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
24
-
-
34248227617
-
Towards a molecular classification of melanoma
-
Fecher LA, Cummings SD, Keefe MJ, et al.: Towards a molecular classification of melanoma. J Clin Oncol 2007; 25: 1606-1620.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1606-1620
-
-
Fecher, L.A.1
Cummings, S.D.2
Keefe, M.J.3
-
25
-
-
84878747070
-
Clinical aspects of a phase i study of PD-0325901, a selective oral MEK inhibitor, in patients with advanced cancer
-
LoRusso PM, Krishnamurthi SS, Rinehart JJ, et al.: Clinical aspects of a phase I study of PD-0325901, a selective oral MEK inhibitor, in patients with advanced cancer. Presented at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2007.
-
Presented at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2007
-
-
Lorusso, P.M.1
Krishnamurthi, S.S.2
Rinehart, J.J.3
-
26
-
-
65649152804
-
Efficacy and safety of AZD6244 (ARRY-142886) as second/third-line treatment of patients (pts) with advanced non-small cell lung cancer (NSCLC)
-
May 20 abstract 8029
-
Tzekova V, Cebotaru C, Ciuleanu TE, et al.: Efficacy and safety of AZD6244 (ARRY-142886) as second/third-line treatment of patients (pts) with advanced non-small cell lung cancer (NSCLC). J Clin Oncol 2008; 26 (May 20 suppl): abstract 8029.
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Tzekova, V.1
Cebotaru, C.2
Ciuleanu, T.E.3
-
27
-
-
23944439944
-
Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies
-
DOI 10.1200/JCO.2005.14.415
-
LoRusso PM, Adjei AA, Varterasian M, et al.: Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies. J Clin Oncol 2005; 23: 5281-5293. (Pubitemid 46206982)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.23
, pp. 5281-5293
-
-
LoRusso, P.M.1
Adjei, A.A.2
Varterasian, M.3
Gadgeel, S.4
Reid, J.5
Mitchell, D.Y.6
Hanson, L.7
DeLuca, P.8
Bruzek, L.9
Piens, J.10
Asbury, P.11
Van Becelaere, K.12
Herrera, R.13
Sebolt-Leopold, J.14
Meyer, M.B.15
-
28
-
-
33749021085
-
Somatic activation of KIT in distinct subtypes of melanoma
-
DOI 10.1200/JCO.2006.06.2984
-
Curtin JA, Busam K, Pinkel D, et al.: Somatic activation of KIT in distinct subtypes of melanoma. J Clin Oncol 2006; 24: 4340-4346. (Pubitemid 46630793)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.26
, pp. 4340-4346
-
-
Curtin, J.A.1
Busam, K.2
Pinkel, D.3
Bastian, B.C.4
-
29
-
-
65649108998
-
AZD6244 (ARRY-142886) vs temozolomide (TMZ) in patients (pts) with advanced melanoma: An open-label, randomized, multicenter, phase II study
-
May 20 abstract 9033.
-
Dummer R, Robert C, Chapman PB, et al.: AZD6244 (ARRY-142886) vs temozolomide (TMZ) in patients (pts) with advanced melanoma: An open-label, randomized, multicenter, phase II study. J Clin Oncol 2008; 26 (May 20 suppl): abstract 9033.
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Dummer, R.1
Robert, C.2
Chapman, P.B.3
-
30
-
-
73949083834
-
MEK1 mutations confer resistance to MEK and B-RAF inhibition
-
Emery CM, Vijayendran KG, Zipser MC, et al.: MEK1 mutations confer resistance to MEK and B-RAF inhibition. Proc Natl Acad Sci USA 2009; 106: 20411-20416.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20411-20416
-
-
Emery, C.M.1
Vijayendran, K.G.2
Zipser, M.C.3
-
31
-
-
77954373338
-
Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function
-
Boni A, Cogdill A, Dang P, et al.: Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function. Cancer Res 2010; 70: 5213-5219.
-
(2010)
Cancer Res
, vol.70
, pp. 5213-5219
-
-
Boni, A.1
Cogdill, A.2
Dang, P.3
-
32
-
-
59649123810
-
Integrating BRAF/MEK inhibitors into combination therapy for melanoma
-
Smalley KS, Flaherty KT:, Integrating BRAF/MEK inhibitors into combination therapy for melanoma. Br J Cancer 2009; 100: 431-435.
-
(2009)
Br J Cancer
, vol.100
, pp. 431-435
-
-
Smalley, K.S.1
Flaherty, K.2
-
33
-
-
32644454916
-
Prognostic significance of autoimmunity during treatment of melanoma with interferon
-
DOI 10.1056/NEJMoa053007
-
Gogas H, Ioannovich J, Dafni U, et al.: Prognostic significance of autoimmunity during treatment of melanoma with interferon. N Engl J Med 2006; 354: 709-718. (Pubitemid 43247141)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.7
, pp. 709-718
-
-
Gogas, H.1
Ioannovich, J.2
Dafni, U.3
Stavropoulou-Giokas, C.4
Frangia, K.5
Tsoutsos, D.6
Panagiotou, P.7
Polyzos, A.8
Papadopoulos, O.9
Stratigos, A.10
Markopoulos, C.11
Bafaloukos, D.12
Pectasides, D.13
Fountzilas, G.14
Kirkwood, J.M.15
-
34
-
-
24944459890
-
Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4
-
Attia P, Phan GQ, Maker AV, et al.: Autoimmunity correlates with tumor regression in patients with metastatic melanoma treated with anti-cytotoxic T-lymphocyte antigen-4. J Clin Oncol 2005; 23: 6043-6053.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6043-6053
-
-
Attia, P.1
Phan, G.Q.2
Maker, A.V.3
-
35
-
-
27244460811
-
Increased incidence of melanoma in renal transplantation recipients
-
DOI 10.1002/cncr.21404
-
Hollenbeak CS, Todd MM, Bilingsley EM, et al.: Increased incidence of melanoma in renal transplantation recipients. Cancer 2005; 104: 1962-1967. (Pubitemid 41513181)
-
(2005)
Cancer
, vol.104
, Issue.9
, pp. 1962-1967
-
-
Hollenbeak, C.S.1
Todd, M.M.2
Billingsley, E.M.3
Harper, G.4
Dyer, A.-M.5
Lengerich, E.J.6
-
36
-
-
0035056017
-
CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
-
DOI 10.1146/annurev.immunol.19.1.565
-
Chambers CA, Kuhns MS, Egen JG, et al.: CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy. Annu Rev Immunol 2001; 19: 565-594. (Pubitemid 32368046)
-
(2001)
Annual Review of Immunology
, vol.19
, pp. 565-594
-
-
Chambers, C.A.1
Kuhns, M.S.2
Egen, J.G.3
Allison, J.P.4
-
37
-
-
0028791059
-
Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4
-
Waterhouse P, Penninger JM, Timms E, et al.: Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science 1995; 270: 985-988.
-
(1995)
Science
, vol.270
, pp. 985-988
-
-
Waterhouse, P.1
Penninger, J.M.2
Timms, E.3
-
38
-
-
78449249018
-
Ipilimumab: Unleashing the power of the immune system through CTLA-4 blockade
-
Boasberg P, Hamid O, O'Day S:, Ipilimumab: Unleashing the power of the immune system through CTLA-4 blockade. Semin Oncol 2010; 37: 440-449.
-
(2010)
Semin Oncol
, vol.37
, pp. 440-449
-
-
Boasberg, P.1
Hamid, O.2
O'Day, S.3
-
39
-
-
0029947568
-
Enhancement of antitumor immunity by CTLA-4 blockade
-
Leach DR, Krummel MF, Allison JP:, Enhancement of antitumor immunity by CTLA-4 blockade. Science 1996; 271: 1734-1736. (Pubitemid 26102823)
-
(1996)
Science
, vol.271
, Issue.5256
, pp. 1734-1736
-
-
Leach, D.R.1
Krummel, M.F.2
Allison, J.P.3
-
40
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al.: Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363: 711-723.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
41
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert C, Thomas L, Bondarenko I, et al.: Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011; 364: 2517-2526.
-
(2011)
N Engl J Med
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
-
42
-
-
77955892831
-
Cytotoxic T lymphocyte-associated antigen 4 blockade with ipilimumab: Long-term follow-up of 179 patients with metastatic melanoma
-
Prieto PA, Yang JC, Sherry RM, et al.: Cytotoxic T lymphocyte-associated antigen 4 blockade with ipilimumab: Long-term follow-up of 179 patients with metastatic melanoma. J Clin Oncol 2010; 28: 15s.
-
(2010)
J Clin Oncol
, vol.28
-
-
Prieto, P.A.1
Yang, J.C.2
Sherry, R.M.3
-
44
-
-
77954899030
-
Phase i study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer J, Drake C, Wollner I, et al.: Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010; 28: 3167-3175.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.1
Drake, C.2
Wollner, I.3
-
45
-
-
77955598758
-
Phase i clinical experience of a targeted TCR-IL2 fusion protein in patients with metastatic malignancies
-
Pennock G, Fishman M, Gonzalez R, et al.: Phase I clinical experience of a targeted TCR-IL2 fusion protein in patients with metastatic malignancies. J Clin Oncol 2009; 27: 3040.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3040
-
-
Pennock, G.1
Fishman, M.2
Gonzalez, R.3
-
46
-
-
70350135349
-
A phase III multi-institutional randomized study of immunization with the gp100:209-217(210M) peptide followed by high-dose IL-2 compared with high-dose IL-2 alone in patients with metastatic melanoma
-
Schwartzentruber DJ, Lawson D, Richards J, et al.: A phase III multi-institutional randomized study of immunization with the gp100:209-217(210M) peptide followed by high-dose IL-2 compared with high-dose IL-2 alone in patients with metastatic melanoma. J Clin Oncol 2009; 27: 18s.
-
(2009)
J Clin Oncol
, vol.27
-
-
Schwartzentruber, D.J.1
Lawson, D.2
Richards, J.3
-
47
-
-
0037058993
-
+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
-
DOI 10.1073/pnas.242600099
-
Yee C, Thompson JA, Byrd D, et al.: Adoptive T cell therapy using antigen-specific CD8 T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells. Proc Natl Acad Sci USA 2002; 99: 16168-16173. (Pubitemid 35462767)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 16168-16173
-
-
Yee, C.1
Thompson, J.A.2
Byrd, D.3
Riddell, S.R.4
Roche, P.5
Celis, E.6
Greenberg, P.D.7
-
48
-
-
0024166189
-
Use of tumor-infiltrating lymphocyts and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report
-
Rosenberg SA, Packard BS, Aebersold PM, et al.: Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report. N Engl J Med 1988; 319: 1676-1680. (Pubitemid 19015247)
-
(1988)
New England Journal of Medicine
, vol.319
, Issue.25
, pp. 1676-1680
-
-
Rosenberg, S.A.1
Packard, B.S.2
Aebersold, P.M.3
Solomon, D.4
Topalian, S.L.5
Toy, S.T.6
Simon, P.7
Lotze, M.T.8
Yang, J.C.9
Seipp, C.A.10
Simpson, C.11
Carter, C.12
Bock, S.13
Schwartzentruber, D.14
Wei, J.P.15
White, D.E.16
-
49
-
-
45549099784
-
Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1
-
DOI 10.1056/NEJMoa0800251
-
Hunder NN, Wallen H, Cao J, et al.: Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1. N Engl J Med 2008; 358: 2698-2703. (Pubitemid 351860862)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.25
, pp. 2698-2703
-
-
Hunder, N.N.1
Wallen, H.2
Cao, J.3
Hendricks, D.W.4
Reilly, J.Z.5
Rodmyre, R.6
Jungbluth, A.7
Gnjatic, S.8
Thompson, J.A.9
Yee, C.10
-
50
-
-
31044446360
-
PARP inhibitors for cancer therapy
-
Curtin NJ:, PARP inhibitors for cancer therapy. Expert Rev Mol Med 2005; 7: 1-20.
-
(2005)
Expert Rev Mol Med
, vol.7
, pp. 1-20
-
-
Curtin, N.1
-
51
-
-
34249070729
-
Oral administration of PARP inhibitor GPI18180 increases the anti-tumor activity of temozolomide against intracranial melanoma in mice
-
abstract 3136
-
Lapidus RG, Tentori L, Graziani G, et al.: Oral administration of PARP inhibitor GPI18180 increases the anti-tumor activity of temozolomide against intracranial melanoma in mice. J Clin Oncol 2005; 23 (16S, Part I): abstract 3136.
-
(2005)
J Clin Oncol
, vol.23
, Issue.16 PART I
-
-
Lapidus, R.G.1
Tentori, L.2
Graziani, G.3
-
52
-
-
68449096428
-
Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial
-
abstract 3
-
O'Shaughnessy J, Osborne C, Pippen J, et al.: Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial. J Clin Oncol 2009; 27 (18s): abstract 3.
-
(2009)
J Clin Oncol
, vol.27
, Issue.18 S
-
-
O'Shaughnessy, J.1
Osborne, C.2
Pippen, J.3
-
53
-
-
0018096512
-
Malignant melanoma and central nervous system metastases. Incidence, diagnosis, treatment and survival
-
Amer MH, Al-Sarraf M, Baker LH, et al.: Malignant melanoma and central nervous system metastases: incidence, diagnosis, treatment and survival. Cancer 1978; 42: 660-668. (Pubitemid 8405861)
-
(1978)
Cancer
, vol.42
, Issue.2
, pp. 660-668
-
-
Amer, M.H.1
Al-Sarraf, M.2
Baker, L.H.3
Vaitkevicius, V.K.4
-
54
-
-
77955253357
-
Association of baseline and on-study tumor biopsy markers with clinical activity in patients (pts) with advanced melanoma treated with ipilimumab
-
abstract 9008
-
Hamid O, Chasalow SD, Tsuchihashi Z, et al.: Association of baseline and on-study tumor biopsy markers with clinical activity in patients (pts) with advanced melanoma treated with ipilimumab. J Clin Oncol 2009; 27 (15s): abstract 9008.
-
(2009)
J Clin Oncol
, vol.27
, Issue.15 S
-
-
Hamid, O.1
Chasalow, S.D.2
Tsuchihashi, Z.3
-
55
-
-
77955874663
-
Treating cancer by targeting the immune system
-
Hwu P:, Treating cancer by targeting the immune system. N Engl J Med 2010; 363: 779-781.
-
(2010)
N Engl J Med
, vol.363
, pp. 779-781
-
-
Hwu, P.1
|