Low safety index of domperidone: Mechanism for increased odds ratio for sudden cardiac death

Acta Cardiologica

Volumn 66, Issue 4, 2011, Pages 421-425

  Hondeghem, Luc M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Domperidone; QTC prolongation; Torsade de pointes (TdP); TRiaD

Indexed keywords

DOMPERIDONE;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG METABOLISM; DRUG SAFETY; FEMALE; HEART ARRHYTHMIA; HEART DISEASE; HEART PERFUSION; HEART REPOLARIZATION; HEART RHYTHM; ISOLATED HEART; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; QT PROLONGATION; RABBIT; RISK; SUDDEN DEATH; TORSADE DES POINTES; TRIANGULATION; TRIANGULATION, REVERSE USE DEPENDENCE, INSTABILITY AND DISPERSION OF THE ACTION POTENTIAL;

ACTION POTENTIALS; ANIMALS; DEATH, SUDDEN, CARDIAC; DOMPERIDONE; DOPAMINE ANTAGONISTS; HEART CONDUCTION SYSTEM; ODDS RATIO; RABBITS; TORSADES DE POINTES; VENTRICULAR FIBRILLATION;

EID: 80051969445     PISSN: 00015385     EISSN: None     Source Type: Journal    
DOI: 10.2143/AC.66.4.2126588     Document Type: Article

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