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80052014650
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The structure of these unfluorinated byproducts retaining an aromatic skeleton is under study
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The structure of these unfluorinated byproducts retaining an aromatic skeleton is under study.
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30
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80051980081
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As already noted by Hu and co-workers, a stoichiometric or an excess amount of the electrophilic reagent was detrimental to the yield.
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As already noted by Hu and co-workers, a stoichiometric or an excess amount of the electrophilic reagent was detrimental to the yield.
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31
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80051966331
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Sulfoximine 7c was entirely recovered at the end of the process.
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Sulfoximine 7c was entirely recovered at the end of the process.
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32
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80051984398
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The use of sulfoximine 1 was not considered because of its very poor solubility under the reaction conditions.
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The use of sulfoximine 1 was not considered because of its very poor solubility under the reaction conditions.
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33
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77952859294
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For other direct methods for trifluoromethylation of alkynes, see and references cited therein
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For other direct methods for trifluoromethylation of alkynes, see: L. Chu, F.-L. Qing, J. Am. Chem. Soc. 2010, 132, 7262-7263 and references cited therein.
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80051995766
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We were not able to separate compound 11b from its dichlorofluoromethylated analog, but both structures were ascertained by NMR spectroscopy and mass spectrometry of the mixture (see Supporting Information)
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We were not able to separate compound 11b from its dichlorofluoromethylated analog, but both structures were ascertained by NMR spectroscopy and mass spectrometry of the mixture (see Supporting Information).
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