Axonal tracing of the normal and regenerating visual pathway of mouse, rat, frog, and fish using manganese-enhanced MRI (MEMRI)

Journal of Magnetic Resonance Imaging

Volumn 34, Issue 3, 2011, Pages 670-675

  Sandvig, Axel ^a,b   Sandvig, Ioanna ^a   Berry, Martin ^c   Olsen, Øystein ^a   Pedersen, Tina Bugge ^a   Brekken, Christian ^a   Thuen, Marte ^a  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b UMEÅ UNIVERSITY HOSPITAL   (Sweden)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

axon; CNS injury; in vivo imaging; MRI; optic nerve; regeneration

Indexed keywords

MANGANESE CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL MOUSE; CELL TRACKING; CONTRAST ENHANCEMENT; CONTROLLED STUDY; FEMALE; FISCHER 344 RAT; FISH; FROG; LENS DISEASE; LONGITUDINAL STUDY; MOUSE; NERVE FIBER REGENERATION; NERVE GRAFT; NERVE PROJECTION; NERVE TRANSECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OPTIC NERVE INJURY; PRIORITY JOURNAL; RAT; SPECIES COMPARISON;

ANIMALS; AXONS; CHLORIDES; CONTRAST MEDIA; DIFFUSION TENSOR IMAGING; FISHES; MANGANESE COMPOUNDS; MICE; NERVE REGENERATION; RANIDAE; RATS; SPECIES SPECIFICITY; VISUAL PATHWAYS;

EID: 80051953649     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.22631     Document Type: Article

References (22)

1. David S, Aguayo AJ,. Axonal elongation into peripheral nervous system bridges after central nervous system injury in rats. Science 1981; 214: 931-933. (Pubitemid 12220099)
2. Berry M, Ahmed Z, Lorber B, Douglas M, Logan A,. Regeneration of axons in the visual system. Restor Neurol Neurosci 2008; 26: 147-174.
3. Park KK, Liu K, Hu Y, et al. Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science 2008; 322: 963-966.
4. Liu K, Lu Y, Lee JK, et al. PTEN deletion enhances the regeneration ability of adult corticospinal neurons. Nat Neurosci 2010; 13: 1075-1081.
5. Kurimoto T, Yin Y, Omura K, et al. Long distance axon regeneration in the mature optic nerve: contributions of oncomodulin, cAMP, and pten gene deletion. J Neurosci 2010; 30: 15654-15663.
6. Christie JC, Webber CA, Martinez JA, Sing B, Zochodne DW,. PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons. J Neurosci 2010; 30: 9306-9315.
7. Sperry RW,. Optic nerve regeneration with return of vision in anurans. J Neurophysiol 1944; 7: 57-69.
8. Sperry RW,. Restoration of vision after crossing the optic nerves and after contralateral transplantation of eye. J Neurophysiol 1945; 8: 15-28.
9. Sperry RW, Arora HL,. Selectivity in regeneration of the oculomotor nerve in the cichlid fish, Astronotus ocellatus. J Embryol Exp Morphol 1965; 14: 307-317.
10. Paques M, Genevois O, Régnier A, et al. Axon-tracing properties of indocyanine green. Arch Ophthalmol 2003; 121: 367-370. (Pubitemid 36298119)
11. Neumann T, Hartig W, Frotscher M,. Retrograde tracing with fluorogold; different methods of tracer detection at the ultrastructural level and neurodegenerative changes of back-filled neurons in long-term studies. J Neurosci Methods 2000; 103: 11-21.
12. Thuen M, Singstad TE, Pedersen TB, et al. Manganese-enhanced MRI of the optic visual pathway and optic nerve injury in adult rats. J Magn Reson Imaging 2005; 22: 492-500. (Pubitemid 41416408)
13. Thuen M, Berry M, Pedersen TB, et al. Manganese-enhanced MRI of the rat visual pathway: acute neuronal toxicity, contrast enhancement, axon resolution, axonal transport and clearance of Mn(2+). J Magn Reson Imaging 2008; 28: 855-865.
14. Thuen M, Olsen O, Berry M, et al. Combination of Mn(2+)-enhanced and diffusion tensor MR imaging gives complementary information about injury and regeneration in the adult rat optic nerve. J Magn Reson Imaging 2009; 29: 39-51.
15. Olsen Ø, Thuen M, Berry M, et al. Axon tracing in the adult rat optic nerve and tract after intravitreal injection of MnDPDP using a semi-automatic segmentation technique. J Magn Reson Imaging 2008; 27: 34-42.
16. Pautler RG, Silva AC, Koretsky AP,. In vivo neuronal tract-tracing using manganese-enhanced magnetic resonance imaging. Magn Reson Med 1998; 40: 740-748. (Pubitemid 28493653)
17. Leergaard TB, Bjaalie JG, Devor A, Wald LL, Dale AM,. In vivo tracing of major rat brain pathways using manganese-enhanced magnetic resonance imaging and three-dimensional digital atlasing. Neuroimage 2003; 20: 1591-1600. (Pubitemid 37468266)
18. Watanabe T, Frahm J, Michaelis T,. Functional mapping of neural pathways in rodent brain in vivo using manganese-enhanced three-dimensional magnetic resonance imaging. NMR Biomed 2004; 17: 554-568. (Pubitemid 40124781)
19. Sloot WN, Gramsbergen JP,. Axonal transport of manganese and its relevance to selective neurotoxicity in the rat basal ganglia. Brain Res 1994; 657: 124-132.
20. Berry M, Carlile J, Hunter A, Tsang W-L, Rosustrei P, Sievers J,. Optic nerve regeneration after intravitreal peripheral nerve implants: trajectories of axons regrowing through the optic chiasm into the optic tracts. J Neurocytol 1999; 28: 721-741.
21. Olsen Ø, Kristoffersen A, Thuen M, et al. Manganese transport in the rat optic nerve evaluated with spatial and time-resolved magnetic resonance imaging. J Magn Reson Imaging 2010; 32: 551-560.
22. Schwalb JM,. Optic nerve glia secrete a low-molecular weight factor that stimulates retinal ganglion cells to regenerate axons in goldfish. Neuroscience 1996; 72: 901-910. (Pubitemid 26139837)